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Volumn 3 JUL, Issue , 2012, Pages

Brain-gut interactions in IBS

Author keywords

Autonomic nervous system; Brain gut axis; Hypothalam opituitary adrenal axis; Irritable bowel syndrome; Pathophysiology

Indexed keywords

AZD 7371; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BUSPIRONE; CISAPRIDE; CORTICOTROPIN RELEASING FACTOR; PLACEBO; ROBALZOTAN; SEROTONIN 3 ANTAGONIST; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; TACHYKININ RECEPTOR ANTAGONIST; TEGASEROD; TOLL LIKE RECEPTOR; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UROCORTIN;

EID: 84866174286     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00127     Document Type: Article
Times cited : (112)

References (182)
  • 1
    • 77955780557 scopus 로고    scopus 로고
    • Meta-analysis: do irritable bowel syndrome symptoms vary between men and women?
    • Adeyemo, M. A., Spiegel, B. M., and Chang, L. (2010). Meta-analysis: do irritable bowel syndrome symptoms vary between men and women? Aliment. Pharmacol. Ther. 32, 738-755.
    • (2010) Aliment Pharmacol. Ther. , vol.32 , pp. 738-755
    • Adeyemo, M.A.1    Spiegel, B.M.2    Chang, L.3
  • 2
    • 47549085728 scopus 로고    scopus 로고
    • The parvo-cellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress. Prog
    • Aguilera, G., Subburaju, S., Young, S., and Chen, J. (2008). The parvo-cellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress. Prog. Brain Res. 170, 29-39.
    • (2008) Brain Res , vol.170 , pp. 29-39
    • Aguilera, G.1    Subburaju, S.2    Young, S.3    Chen, J.4
  • 3
    • 3142724031 scopus 로고    scopus 로고
    • Tolllike receptor signalling
    • Akira, S., and Takeda, K. (2004). Tolllike receptor signalling. Nat. Rev. Immunol. 4, 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 4
    • 0032899957 scopus 로고    scopus 로고
    • The role of corticotropin-releasing factor in depression and anxiety disorders
    • Arborelius, L., Owens, M. J., Plotsky, P. M., and Nemeroff, C. B. (1999). The role of corticotropin-releasing factor in depression and anxiety disorders. J. Endocrinol. 160, 1-12.
    • (1999) J. Endocrinol. , vol.160 , pp. 1-12
    • Arborelius, L.1    Owens, M.J.2    Plotsky, P.M.3    Nemeroff, C.B.4
  • 5
    • 50849102261 scopus 로고    scopus 로고
    • Review article: the psy-choneuroimmunology of irritable bowel syndrome - an exploration of interactions between psychological, neurological and immunologi-cal observations
    • Arebi, N., Gurmany, S., Bullas, D., Hobson, A., Stagg, A., and Kamm, M. (2008). Review article: the psy-choneuroimmunology of irritable bowel syndrome - an exploration of interactions between psychological, neurological and immunologi-cal observations. Aliment. Pharmacol. Ther. 28, 830-840.
    • (2008) Aliment. Pharmacol. Ther. , vol.28 , pp. 830-840
    • Arebi, N.1    Gurmany, S.2    Bullas, D.3    Hobson, A.4    Stagg, A.5    Kamm, M.6
  • 6
    • 58849084736 scopus 로고    scopus 로고
    • Design and synthesis of piperazinylpyridine derivatives as novel 5-HT1A agonists/5-HT3 antagonists for the treatment of irritable bowel syndrome (IBS)
    • Asagarasu, A., Matsui, T., Hayashi, H., Tamaoki, S., Yamauchi, Y., and Sato, M. (2009). Design and synthesis of piperazinylpyridine derivatives as novel 5-HT1A agonists/5-HT3 antagonists for the treatment of irritable bowel syndrome (IBS). Chem. Pharm. Bull. 57, 34-42.
    • (2009) Chem. Pharm. Bull. , vol.57 , pp. 34-42
    • Asagarasu, A.1    Matsui, T.2    Hayashi, H.3    Tamaoki, S.4    Yamauchi, Y.5    Sato, M.6
  • 7
    • 30044442329 scopus 로고    scopus 로고
    • Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome
    • Atkinson, W., Lockhart, S., Whor-well, P. J., Keevil, B., and Houghton, L. A. (2006). Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome. Gastroenterology 130, 34-43.
    • (2006) Gastroenterology , vol.130 , pp. 34-43
    • Atkinson, W.1    Lockhart, S.2    Whor-well, P.J.3    Keevil, B.4    Houghton, L.A.5
  • 8
    • 4644287837 scopus 로고    scopus 로고
    • Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial
    • Atkinson, W., Sheldon, T. A., Shaath, N., and Whorwell, P. J. (2004). Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut. 53, 1459-1464.
    • (2004) Gut , vol.53 , pp. 1459-1464
    • Atkinson, W.1    Sheldon, T.A.2    Shaath, N.3    Whorwell, P.J.4
  • 9
    • 0036016831 scopus 로고    scopus 로고
    • Gastrointestinal perception: pathophysiological implications
    • Azpiroz, F. (2002). Gastrointestinal perception: pathophysiological implications. Neurogastroenterol. Motil. 14, 229-239.
    • (2002) Neurogastroenterol. Motil. , vol.14 , pp. 229-239
    • Azpiroz, F.1
  • 11
    • 1342281225 scopus 로고    scopus 로고
    • CRF and CRF receptors: roleinstress responsivity and other behaviors
    • Bale, T. L., and Vale, W. W. (2004). CRF andCRF receptors: roleinstress responsivity and other behaviors. Annu. Rev. Pharmacol. Toxicol. 44, 525-557.
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 525-557
    • Bale, T.L.1    Vale, W.W.2
  • 15
    • 58049215463 scopus 로고    scopus 로고
    • The 5-HT3 receptor - the relation-shipbetween structure andfunction
    • Barnes, N. M., Hales, T. G., Lummis, S. C., and Peters, J. A. (2009). The 5-HT3 receptor - the relation-shipbetween structure andfunction. Neuropharmacology. 56, 273-284.
    • (2009) Neuropharmacology , vol.56 , pp. 273-284
    • Barnes, N.M.1    Hales, T.G.2    Lummis, S.C.3    Peters, J.A.4
  • 18
    • 77951667119 scopus 로고    scopus 로고
    • Altered brain structure in irritable bowel syndrome: potential contributions of pre-existing and disease-driven factors
    • Blankstein, U., Chen, J., Diamant, N. E., and Davis, K. D. (2010). Altered brain structure in irritable bowel syndrome: potential contributions of pre-existing and disease-driven factors. Gastroenterology 138, 1783-1789.
    • (2010) Gastroenterology , vol.138 , pp. 1783-1789
    • Blankstein, U.1    Chen, J.2    Diamant, N.E.3    Davis, K.D.4
  • 19
    • 79955996102 scopus 로고    scopus 로고
    • Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders
    • Bravo, J. A., Dinan, T. G., and Cryan, J. F. (2011). Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders. Int. J. Neuropsychopharmacol. 14, 666-683.
    • (2011) Int. J. Neuropsychopharma-col. , vol.14 , pp. 666-683
    • Bravo, J.A.1    Dinan, T.G.2    Cryan, J.F.3
  • 20
    • 79751499345 scopus 로고    scopus 로고
    • Differential expression of toll-like receptors in patients with irritable bowel syndrome
    • Brint, E. K., MacSharry, J., Fanning, A., Shanahan, F., and Quigley, E. M. (2011). Differential expression of toll-like receptors in patients with irritable bowel syndrome. Am. J. Gastroenterol. 106, 329-336.
    • (2011) Am. J. Gastroenterol. , vol.106 , pp. 329-336
    • Brint, E.K.1    MacSharry, J.2    Fanning, A.3    Shanahan, F.4    Quigley, E.M.5
  • 21
    • 0034672322 scopus 로고    scopus 로고
    • Variations in maternal care in infancy regulate the development of stress reactivity
    • Caldji, C., Diorio, J., and Meaney, M. J. (2000). Variations in maternal care in infancy regulate the development of stress reactivity. Biol. Psychiatry 48, 1164-1174.
    • (2000) Biol. Psychiatry. , vol.48 , pp. 1164-1174
    • Caldji, C.1    Diorio, J.2    Meaney, M.J.3
  • 22
    • 79551714477 scopus 로고    scopus 로고
    • LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin
    • Camilleri, M. (2011). LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin. Neurogastroenterol. Motil. 23, 193-200.
    • (2011) Neurogastroenterol. Motil. , vol.23 , pp. 193-200
    • Camilleri, M.1
  • 23
    • 70350567652 scopus 로고    scopus 로고
    • Current and novel therapeutic options for irritable bowel syndrome management
    • Camilleri, M., and Andresen, V. (2009). Current and novel therapeutic options for irritable bowel syndrome management. Dig. Liver Dis. 41, 854-862.
    • (2009) Dig. Liver Dis. , vol.41 , pp. 854-862
    • Camilleri, M.1    Andresen, V.2
  • 24
    • 0031030741 scopus 로고    scopus 로고
    • Review article: irritable bowel syndrome
    • Camilleri, M., and Choi, M. G. (1997). Review article: irritable bowel syndrome. Aliment. Pharmacol. Ther. 11, 3-15.
    • (1997) Aliment. Pharmacol. Ther. , vol.11 , pp. 3-15
    • Camilleri, M.1    Choi, M.G.2
  • 25
    • 44349130441 scopus 로고    scopus 로고
    • A placebo-controlled trial of prucalopride for severe chronic constipation
    • Camilleri,M., Kerstens, R., Rykx, A., and Vandeplassche, L. (2008). A placebo-controlled trial of prucalopride for severe chronic constipation. N. Engl. J. Med. 358, 2344-2354.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2344-2354
    • Camilleri, M.1    Kerstens, R.2    Rykx, A.3    Vandeplassche, L.4
  • 26
    • 0029024923 scopus 로고
    • Characterization of a postjunctional 5-HT receptor mediating relaxation of guineapig isolated ileum
    • Carter, D., Champney, M., Hwang, B., and Eglen, R. M. (1995). Characterization of a postjunctional 5-HT receptor mediating relaxation of guineapig isolated ileum. Eur. J. Pharmacol. 280, 243-250.
    • (1995) Eur. J. Pharmacol. , vol.280 , pp. 243-250
    • Carter, D.1    Champney, M.2    Hwang, B.3    Eglen, R.M.4
  • 29
    • 77950520996 scopus 로고    scopus 로고
    • Ischemic colitis and complications of constipation associated with the use of alosetron under a risk management plan: clinical characteristics, outcomes, and incidences
    • Chang, L., Tong, K., and Ameen, V. (2010). Ischemic colitis and complications of constipation associated with the use of alosetron under a risk management plan: clinical characteristics, outcomes, and incidences. Am. J. Gastroenterol. 105, 866-875.
    • (2010) Am. J. Gastroenterol. , vol.105 , pp. 866-875
    • Chang, L.1    Tong, K.2    Ameen, V.3
  • 30
    • 79955933357 scopus 로고    scopus 로고
    • White matter abnormalities in irritable bowel syndrome and relation to individual factors
    • Chen, J. Y., Blankstein, U., Diamant, N. E., and Davis, K. D. (2011). White matter abnormalities in irritable bowel syndrome and relation to individual factors. Brain Res. 1392, 121-131.
    • (2011) Brain Res , vol.1392 , pp. 121-131
    • Chen, J.Y.1    Blankstein, U.2    Diamant, N.E.3    Davis, K.D.4
  • 31
    • 80052427809 scopus 로고    scopus 로고
    • Pharmaco-logic and complementary and alternative medicine therapies for irritable bowel syndrome
    • Chey, W. D., Maneerattaporn, M., and Saad, R. (2011). Pharmaco-logic and complementary and alternative medicine therapies for irritable bowel syndrome. Gut Liver 5, 253-266.
    • (2011) Gut Liver , vol.5 , pp. 253-266
    • Chey, W.D.1    Maneerattaporn, M.2    Saad, R.3
  • 32
    • 70350004219 scopus 로고    scopus 로고
    • Irritable bowel syndrome: towards biomarker identification
    • Clarke, G., Quigley, E. M., Cryan, J. F., and Dinan, T. G. (2009). Irritable bowel syndrome: towards biomarker identification. Trends Mol. Med. 15, 478-489.
    • (2009) Trends Mol. Med. , vol.15 , pp. 478-489
    • Clarke, G.1    Quigley, E.M.2    Cryan, J.F.3    Dinan, T.G.4
  • 34
    • 65449159712 scopus 로고    scopus 로고
    • The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease
    • Collins, S. M., and Bercik, P. (2009). The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 136, 2003-2014.
    • (2009) Gastroenterology , vol.136 , pp. 2003-2014
    • Collins, S.M.1    Bercik, P.2
  • 35
    • 19944418868 scopus 로고    scopus 로고
    • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
    • Cryan, J. F., Valentino, R. J., and Lucki, I. (2005). Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci. Biobehav. Rev. 29, 547-569.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 547-569
    • Cryan, J.F.1    Valentino, R.J.2    Lucki, I.3
  • 36
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., and Kelley, K. W. (2008). From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 9, 46-56.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 37
    • 3142604662 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of the mouse CRF2(a) receptor splice variant
    • Dautzenberg, F. M., Higelin, J., Wille, S., and Brauns, O. (2004). Molecular cloning and functional expression of the mouse CRF2(a) receptor splice variant. Regul. Pept. 121, 89-97.
    • (2004) Regul. Pept. , vol.121 , pp. 89-97
    • Dautzenberg, F.M.1    Higelin, J.2    Wille, S.3    Brauns, O.4
  • 38
    • 37849029806 scopus 로고    scopus 로고
    • Cortical thinning in IBS: implications for homeostatic, attention, and pain processing
    • Davis,K.D., Pope, G., Chen, J., Kwan,C. L., Crawley, A. P., and Diamant, N. E. (2008). Cortical thinning in IBS: implications for homeostatic, attention, and pain processing. Neurology 70, 153-154.
    • (2008) Neurology , vol.70 , pp. 153-154
    • Davis, K.D.1    Pope, G.2    Chen, J.3    Kwan, C.L.4    Crawley, A.P.5    Diamant, N.E.6
  • 39
    • 54749094008 scopus 로고    scopus 로고
    • Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of mus-carinic receptors
    • Dinan, T. G., Clarke, G., Quigley, E. M., Scott, L. V., Shanahan, F., Cryan, J., Cooney, J., and Keeling, P. W. (2008). Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of mus-carinic receptors. Am. J. Gastroen-terol. 103, 2570-2576.
    • (2008) Am. J. Gastroen-terol. , vol.103 , pp. 2570-2576
    • Dinan, T.G.1    Clarke, G.2    Quigley, E.M.3    Scott, L.V.4    Shanahan, F.5    Cryan, J.6    Cooney, J.7    Keeling, P.W.8
  • 42
    • 0031812434 scopus 로고    scopus 로고
    • Presidential address: gastrointestinal illness and the biopsychosocial model
    • Drossman, D. A. (1998). Presidential address: gastrointestinal illness and the biopsychosocial model. Psycho-som. Med. 60, 258-267.
    • (1998) Psycho-som. Med. , vol.60 , pp. 258-267
    • Drossman, D.A.1
  • 44
    • 0032830546 scopus 로고    scopus 로고
    • Psychosocial aspects of the functional gastrointestinal disorders
    • Drossman, D. A., Creed, F. H., Olden, K. W., Svedlund, J., Toner, B. B., and Whitehead, W. E. (1999). Psychosocial aspects of the functional gastrointestinal disorders. Gut 45(Suppl. 2), 225-230.
    • (1999) Gut , vol.45 , Issue.SUPPL. 2 , pp. 225-230
    • Drossman, D.A.1    Creed, F.H.2    Olden, K.W.3    Svedlund, J.4    Toner, B.B.5    Whitehead, W.E.6
  • 45
    • 53149147052 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trialof the 5-HT1A receptor antagonist AZD7371 tartrate monohydrate (robalzotan tartrate monohydrate) in patients with irritable bowel syndrome
    • Drossman, D. A., Danilewitz, M., Naesdal, J., Hwang, C., Adler, J., and Silberg, D. G. (2008). Randomized, double-blind, placebo-controlled trialof the 5-HT1A receptor antagonist AZD7371 tartrate monohydrate (robalzotan tartrate monohydrate) in patients with irritable bowel syndrome. Am. J. Gastroenterol. 103, 2562-2569.
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 2562-2569
    • Drossman, D.A.1    Danilewitz, M.2    Naesdal, J.3    Hwang, C.4    Adler, J.5    Silberg, D.G.6
  • 46
    • 33749256469 scopus 로고    scopus 로고
    • Rome III new standard for functional gastrointestinal disorders
    • Drossman, D. A., and Dumitrascu, D. L. (2006). Rome III new standard for functional gastrointestinal disorders. J. Gastrointestin. Liver Dis. 15, 237-241.
    • (2006) J. Gastrointestin. Liver Dis , vol.15 , pp. 237-241
    • Drossman, D.A.1    Dumitrascu, D.L.2
  • 50
    • 0017576627 scopus 로고
    • The need for a new medical model: a challenge for biomedicine
    • Engel, G. L. (1977). The need for a new medical model: a challenge for biomedicine. Science 196, 129-136.
    • (1977) Science , vol.196 , pp. 129-136
    • Engel, G.L.1
  • 51
    • 0032032515 scopus 로고    scopus 로고
    • The excitatory effects of the amygdala on hypothalamo-pituitary-adrenocortical responses are mediated by hypothalamic nor-epinephrine,serotonin,and CRF-41
    • Feldman, S., and Weidenfeld, J. (1998). The excitatory effects of the amygdala on hypothalamo-pituitary-adrenocortical responses are mediated by hypothalamic nor-epinephrine,serotonin,and CRF-41. Brain Res. Bull. 45, 389-393.
    • (1998) Brain Res. Bull , vol.45 , pp. 389-393
    • Feldman, S.1    Weidenfeld, J.2
  • 52
    • 72449132032 scopus 로고    scopus 로고
    • Selective natural kappa opioid and cannabinoid receptor agonists with a potential role in the treatment of gastrointestinal dysfunction
    • Fichna, J., Schicho, R., Janecka,A., Zjaw-iony, J. K., and Storr, M. (2009). Selective natural kappa opioid and cannabinoid receptor agonists with a potential role in the treatment of gastrointestinal dysfunction. Drug News Perspect. 22, 383-392.
    • (2009) Drug News Perspect , vol.22 , pp. 383-392
    • Fichna, J.1    Schicho, R.2    Janecka, A.3    Zjaw-iony, J.K.4    Storr, M.5
  • 53
    • 61649089108 scopus 로고    scopus 로고
    • Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis
    • Ford, A. C., Talley, N. J., Schoenfeld, P. S., Quigley, E. M., and Moayyedi, P. (2009). Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis. Gut 58, 367-378.
    • (2009) Gut , vol.58 , pp. 367-378
    • Ford, A.C.1    Talley, N.J.2    Schoenfeld, P.S.3    Quigley, E.M.4    Moayyedi, P.5
  • 54
    • 33846434057 scopus 로고    scopus 로고
    • Role of corticotropin-releasing hormone in irritable bowel syndrome and intestinal inflammation
    • Fukudo, S. (2007). Role of corticotropin-releasing hormone in irritable bowel syndrome and intestinal inflammation. J. Gastroenterol. 42(Suppl. 17), 48-51.
    • (2007) J. Gastroenterol. , vol.42 , Issue.SUPPL. 17 , pp. 48-51
    • Fukudo, S.1
  • 55
    • 79953086768 scopus 로고    scopus 로고
    • Gene, environment, and brain-gut interactions in irritable bowel syndrome
    • Fukudo, S., and Kanazawa, M. (2011). Gene, environment, and brain-gut interactions in irritable bowel syndrome. J. Gastroenterol. Hepatol. 26(Suppl. 3), 110-115.
    • (2011) J. Gastroenterol. Hepatol. , vol.26 , Issue.SUPPL 3 , pp. 110-115
    • Fukudo, S.1    Kanazawa, M.2
  • 56
    • 0031807954 scopus 로고    scopus 로고
    • Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome
    • Fukudo, S., Nomura, T., and Hongo, M. (1998). Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome. Gut 42, 845-849.
    • (1998) Gut , vol.42 , pp. 845-849
    • Fukudo, S.1    Nomura, T.2    Hongo, M.3
  • 57
    • 53749094942 scopus 로고    scopus 로고
    • Neuromodulatory processes of the brain-gut axis
    • Gaman, A., and Kuo, B. (2008). Neuromodulatory processes of the brain-gut axis. Neuromodulation 11, 249-259.
    • (2008) Neuromodulation , vol.11 , pp. 249-259
    • Gaman, A.1    Kuo, B.2
  • 58
    • 52049090187 scopus 로고    scopus 로고
    • The role of serotonin in irritable bowel syndrome: implications for management
    • Garvin, B., and Wiley, J. W. (2008). The role of serotonin in irritable bowel syndrome: implications for management. Curr. Gastroenterol. Rep. 10, 363-368.
    • (2008) Curr. Gastroenterol. Rep. , vol.10 , pp. 363-368
    • Garvin, B.1    Wiley, J.W.2
  • 59
    • 33846347644 scopus 로고    scopus 로고
    • The serotonin signaling system: from basic understanding to drug development for functional GI disorders
    • Gershon, M. D., and Tack, J. (2007). The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 132, 397-414.
    • (2007) Gastroenterology , vol.132 , pp. 397-414
    • Gershon, M.D.1    Tack, J.2
  • 60
    • 0035206886 scopus 로고    scopus 로고
    • Coex-pression of ER beta with ER alpha and progestin receptor proteins in the female rat forebrain: effects of estradiol treatment
    • Greco, B., Allegretto, E. A., Tetel, M. J., and Blaustein, J. D. (2001). Coex-pression of ER beta with ER alpha and progestin receptor proteins in the female rat forebrain: effects of estradiol treatment. Endocrinology 142, 5172-5181.
    • (2001) Endocrinology , vol.142 , pp. 5172-5181
    • Greco, B.1    Allegretto, E.A.2    Tetel, M.J.3    Blaustein, J.D.4
  • 61
    • 0035793937 scopus 로고    scopus 로고
    • Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats
    • Greenwood-Van, M. B., Gibson, M., Gunter, W., Shepard, J., Foreman, R., and Myers, D. (2001). Stereotaxic delivery of corticosterone to the amygdala modulates colonic sensitivity in rats. Brain Res. 893, 135-142.
    • (2001) Brain Res , vol.893 , pp. 135-142
    • Greenwood-Van, M.B.1    Gibson, M.2    Gunter, W.3    Shepard, J.4    Foreman, R.5    Myers, D.6
  • 62
    • 58849083649 scopus 로고    scopus 로고
    • Frequency and severity of the symptoms of irritable bowel syndrome across the anxiety disorders and depression
    • Gros, D. F., Antony, M. M., McCabe, R. E., and Swinson, R. P. (2009). Frequency and severity of the symptoms of irritable bowel syndrome across the anxiety disorders and depression. J. Anxiety Disord. 23, 290-296.
    • (2009) J. Anxiety Disord. , vol.23 , pp. 290-296
    • Gros, D.F.1    Antony, M.M.2    McCabe, R.E.3    Swinson, R.P.4
  • 63
    • 79951562467 scopus 로고    scopus 로고
    • Centrally acting therapies for irritable bowel syndrome
    • Grover, M., and Drossman, D. A. (2011). Centrally acting therapies for irritable bowel syndrome. Gas-troenterol. Clin. North Am. 40, 183-206.
    • (2011) Gas-troenterol. Clin. North Am. , vol.40 , pp. 183-206
    • Grover, M.1    Drossman, D.A.2
  • 64
    • 79955686853 scopus 로고    scopus 로고
    • Current developments for the diagnosis and treatment of irritable bowel syndrome
    • Grundmann, O., Yoon, S. L., and Moshiree, B. (2010). Current developments for the diagnosis and treatment of irritable bowel syndrome. Curr. Pharm. Des. 16, 3638-3645.
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 3638-3645
    • Grundmann, O.1    Yoon, S.L.2    Moshiree, B.3
  • 65
    • 0025793195 scopus 로고
    • Conditioned emotional response in rats enhances colonic motility through the central release of corticotropin-releasing factor
    • Gue, M., Junien, J. L., and Bueno, L. (1991). Conditioned emotional response in rats enhances colonic motility through the central release of corticotropin-releasing factor. Gastroenterology 100, 964-970.
    • (1991) Gastroenterology , vol.100 , pp. 964-970
    • Gue, M.1    Junien, J.L.2    Bueno, L.3
  • 66
    • 79957969679 scopus 로고    scopus 로고
    • Amygdala activation by corticosterone alters visceral and somatic pain in cycling female rats
    • Gustafsson, J. K., and Greenwood-Van, M. B. (2011). Amygdala activation by corticosterone alters visceral and somatic pain in cycling female rats. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G1080-G1085.
    • (2011) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.300
    • Gustafsson, J.K.1    Greenwood-Van, M.B.2
  • 69
    • 0242352373 scopus 로고    scopus 로고
    • Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness
    • doi:10.1016/j.yfrne.2003.07.001
    • Herman, J. P., Figueiredo, H., Mueller, N. K., Ulrich-Lai, Y., Ostrander, M. M., Choi, D. C., and Cullinan, W. E. (2003). Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front. Neuroendocrinol. 24:7. doi:10.1016/j.yfrne.2003.07.001
    • (2003) Front. Neuroendocrinol. , vol.24 , pp. 7
    • Herman, J.P.1    Figueiredo, H.2    Mueller, N.K.3    Ulrich-Lai, Y.4    Ostrander, M.M.5    Choi, D.C.6    Cullinan, W.E.7
  • 70
    • 0036282244 scopus 로고    scopus 로고
    • The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers
    • Houghton, L. A., Lea, R., Jackson, N., and Whorwell,P.J. (2002).The menstrual cycle affects rectal sensitivity in patients with irritable bowel syndrome but not healthy volunteers. Gut 50, 471-474.
    • (2002) Gut , vol.50 , pp. 471-474
    • Houghton, L.A.1    Lea, R.2    Jackson, N.3    Whorwell, P.J.4
  • 71
    • 0000432665 scopus 로고    scopus 로고
    • Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor
    • Hsu, S. Y., and Hsueh, A. J. (2001). Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor. Nat. Med. 7, 605-611.
    • (2001) Nat. Med. , vol.7 , pp. 605-611
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 73
    • 77649275461 scopus 로고    scopus 로고
    • Cannabinoids and the gut: new developments and emerging concepts
    • Izzo, A. A., and Sharkey, K. A. (2010). Cannabinoids and the gut: new developments and emerging concepts. Pharmacol. Ther. 126, 21-38.
    • (2010) Pharmacol. Ther. , vol.126 , pp. 21-38
    • Izzo, A.A.1    Sharkey, K.A.2
  • 75
    • 0037326780 scopus 로고    scopus 로고
    • Anxiety and depression are related to autonomic nervous system function in women with irritable bowel syndrome
    • Jarrett, M. E., Burr, R. L., Cain, K. C., Hertig, V., Weisman, P., and Heitkemper, M. M. (2003). Anxiety and depression are related to autonomic nervous system function in women with irritable bowel syndrome. Dig. Dis. Sci. 48, 386-394.
    • (2003) Dig. Dis. Sci. , vol.48 , pp. 386-394
    • Jarrett, M.E.1    Burr, R.L.2    Cain, K.C.3    Hertig, V.4    Weisman, P.5    Heitkemper, M.M.6
  • 76
    • 0037302873 scopus 로고    scopus 로고
    • Cytokines: regulation of the hypothalamo - pituitary - adrenocortical axis
    • John, C. D., and Buckingham, J. C. (2003). Cytokines: regulation of the hypothalamo - pituitary - adrenocortical axis. Curr. Opin. Pharmacol. 3, 78-84.
    • (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 78-84
    • John, C.D.1    Buckingham, J.C.2
  • 77
    • 77649092390 scopus 로고    scopus 로고
    • Brain activation in response to visceral stimulation in rats with amygdala implants of corticosterone: an FMRI study
    • doi:10.1371/journal.pone.0008573
    • Johnson, A. C., Myers, B., Lazovic, J., Towner, R., and Greenwood-Van, M. B. (2010). Brain activation in response to visceral stimulation in rats with amygdala implants of corticosterone: an FMRI study. PLoS ONE 5, e8573. doi:10.1371/journal.pone.0008573
    • (2010) PLoS ONE , vol.5
    • Johnson, A.C.1    Myers, B.2    Lazovic, J.3    Towner, R.4    Greenwood-Van, M.B.5
  • 78
    • 0032418777 scopus 로고    scopus 로고
    • The menstrual cycle and its effect oninflammatorybowel disease and irritable bowel syndrome: a prevalence study
    • Kane, S. V., Sable, K., and Hanauer, S. B. (1998). The menstrual cycle and its effect oninflammatorybowel disease and irritable bowel syndrome: a prevalence study. Am. J. Gastroen-terol. 93, 1867-1872.
    • (1998) Am. J. Gastroen-terol. , vol.93 , pp. 1867-1872
    • Kane, S.V.1    Sable, K.2    Hanauer, S.B.3
  • 82
    • 0034141638 scopus 로고    scopus 로고
    • Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus
    • Kirby, L. G., Rice, K. C., and Valentino, R. J. (2000). Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus. Neuropsychopharmacology 22, 148-162.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 148-162
    • Kirby, L.G.1    Rice, K.C.2    Valentino, R.J.3
  • 83
    • 0032230337 scopus 로고    scopus 로고
    • Molecular identification and analysis of a novel human corticotropin-releasing factor (CRF) receptor: the CRF2gamma receptor
    • Kostich, W. A., Chen, A., Sperle, K., and Largent, B. L. (1998). Molecular identification and analysis of a novel human corticotropin-releasing factor (CRF) receptor: the CRF2gamma receptor. Mol. Endocrinol. 12, 1077-1085.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1077-1085
    • Kostich, W.A.1    Chen, A.2    Sperle, K.3    Largent, B.L.4
  • 84
    • 0034066325 scopus 로고    scopus 로고
    • The 5-HT(3) receptor antagonist alosetron inhibits the col-orectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat
    • Kozlowski, C. M., Green, A., Grundy, D., Boissonade, F. M., and Bountra, C. (2000). The 5-HT(3) receptor antagonist alosetron inhibits the col-orectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat. Gut 46, 474-480.
    • (2000) Gut , vol.46 , pp. 474-480
    • Kozlowski, C.M.1    Green, A.2    Grundy, D.3    Boissonade, F.M.4    Bountra, C.5
  • 85
    • 27144513213 scopus 로고    scopus 로고
    • Abnormal fore-brain activity in functional bowel disorder patients with chronic pain
    • Kwan, C. L., Diamant, N. E., Pope, G., Mikula, K., Mikulis, D. J., and Davis, K. D. (2005). Abnormal fore-brain activity in functional bowel disorder patients with chronic pain. Neurology 65, 1268-1277.
    • (2005) Neurology , vol.65 , pp. 1268-1277
    • Kwan, C.L.1    Diamant, N.E.2    Pope, G.3    Mikula, K.4    Mikulis, D.J.5    Davis, K.D.6
  • 86
    • 44449100027 scopus 로고    scopus 로고
    • Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: a network analysis
    • Labus, J. S., Naliboff, B. N., Fallon, J., Berman, S. M., Suyenobu, B., Bueller, J. A., Mandelkern, M., and Mayer, E. A. (2008). Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: a network analysis. Neuroimage 41, 1032-1043.
    • (2008) Neuroimage , vol.41 , pp. 1032-1043
    • Labus, J.S.1    Naliboff, B.N.2    Fallon, J.3    Berman, S.M.4    Suyenobu, B.5    Bueller, J.A.6    Mandelkern, M.7    Mayer, E.A.8
  • 88
    • 84856190424 scopus 로고    scopus 로고
    • Stress and visceral pain: from animal models to clinical therapies
    • Larauche, M., Mulak, A., and Tache, Y. (2012). Stress and visceral pain: from animal models to clinical therapies. Exp. Neurol. 233, 49-67.
    • (2012) Exp. Neurol. , vol.233 , pp. 49-67
    • Larauche, M.1    Mulak, A.2    Tache, Y.3
  • 89
    • 30044439350 scopus 로고    scopus 로고
    • Novel evidence for hypersensitivity of visceral sensory neural circuitry in irritable bowel syndrome patients
    • Lawal, A., Kern, M., Sidhu, H., Hof-mann, C., and Shaker, R. (2006). Novel evidence for hypersensitivity of visceral sensory neural circuitry in irritable bowel syndrome patients. Gastroenterology 130, 26-33.
    • (2006) Gastroenterology , vol.130 , pp. 26-33
    • Lawal, A.1    Kern, M.2    Sidhu, H.3    Hof-mann, C.4    Shaker, R.5
  • 90
    • 36148968922 scopus 로고    scopus 로고
    • Irritable bowel syndrome is more common in women regardless of the menstrual phase: a Rome II-based survey
    • Lee, S. Y., Kim, J. H., Sung, I. K., Park, H. S., Jin, C. J., Choe, W. H., Kwon, S. Y., Lee, C. H., and Choi, K. W. (2007). Irritable bowel syndrome is more common in women regardless of the menstrual phase: a Rome II-based survey. J. Korean Med. Sci. 22, 851-854.
    • (2007) J. Korean Med. Sci. , vol.22 , pp. 851-854
    • Lee, S.Y.1    Kim, J.H.2    Sung, I.K.3    Park, H.S.4    Jin, C.J.5    Choe, W.H.6    Kwon, S.Y.7    Lee, C.H.8    Choi, K.W.9
  • 93
    • 66749157266 scopus 로고    scopus 로고
    • The selective 5-hydroxytryptamine 1A antagonist, AZD7371 [3(R)-(N,N-dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide (R,R)-tartrate monohydrate] (robalzotan tartrate monohydrate), inhibits visceral pain-related visceromotor, but not autonomic cardiovascular, responses to colorectal distension in rats
    • Lindstrom, E., Ravnefjord, A., Brus-berg, M., Hjorth, S., Larsson, H., and Martinez, V. (2009). The selective 5-hydroxytryptamine 1A antagonist, AZD7371 [3(R)-(N,N-dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide (R,R)-tartrate monohydrate] (robalzotan tartrate monohydrate), inhibits visceral pain-related visceromotor, but not autonomic cardiovascular, responses to colorectal distension in rats. J. Pharmacol. Exp. Ther. 329, 1048-1055.
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 1048-1055
    • Lindstrom, E.1    Ravnefjord, A.2    Brus-berg, M.3    Hjorth, S.4    Larsson, H.5    Martinez, V.6
  • 94
    • 32644477565 scopus 로고    scopus 로고
    • Regulation of behavioral responses by corticotropin-releasing factor
    • Lowry, C. A., and Moore, F. L. (2006). Regulation of behavioral responses by corticotropin-releasing factor. Gen. Comp. Endocrinol. 146, 19-27.
    • (2006) Gen. Comp. Endocrinol. , vol.146 , pp. 19-27
    • Lowry, C.A.1    Moore, F.L.2
  • 95
    • 37349126918 scopus 로고    scopus 로고
    • Corticotropin-releasing factor 1 and 2 receptors in the dorsal raphe differentially affect serotonin release in the nucleus accumbens
    • Lukkes, J. L., Forster, G. L., Renner, K. J., and Summers, C. H. (2008). Corticotropin-releasing factor 1 and 2 receptors in the dorsal raphe differentially affect serotonin release in the nucleus accumbens. Eur. J. Pharmacol. 578, 185-193.
    • (2008) Eur. J. Pharmacol. , vol.578 , pp. 185-193
    • Lukkes, J.L.1    Forster, G.L.2    Renner, K.J.3    Summers, C.H.4
  • 96
    • 3042853382 scopus 로고    scopus 로고
    • The brain-gut axis in irritable bowel syndrome - clinical aspects
    • Mach, T. (2004). The brain-gut axis in irritable bowel syndrome - clinical aspects. Med. Sci. Monit. 10, RA125-RA131.
    • (2004) Med. Sci. Monit. , vol.10
    • Mach, T.1
  • 98
    • 33750537247 scopus 로고    scopus 로고
    • CRF1 receptors as a therapeutic target for irritable bowel syndrome
    • Martinez, V., and Tache, Y. (2006). CRF1 receptors as a therapeutic target for irritable bowel syndrome. Curr. Pharm. Des. 12, 4071-4088.
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 4071-4088
    • Martinez, V.1    Tache, Y.2
  • 99
    • 1942453392 scopus 로고    scopus 로고
    • Central CRF, urocortins and stress increase colonic transit via CRF1 receptors while activation of CRF2 receptors delays gastric transit in mice
    • Martinez, V., Wang, L., Rivier, J., Grigoriadis, D., and Tache, Y. (2004). Central CRF, urocortins and stress increase colonic transit via CRF1 receptors while activation of CRF2 receptors delays gastric transit in mice. J. Physiol. (Lond.) 556(Pt 1), 221-234.
    • (2004) J. Physiol. (Lond. ) , vol.556 , Issue.PART 1 , pp. 221-234
    • Martinez, V.1    Wang, L.2    Rivier, J.3    Grigoriadis, D.4    Tache, Y.5
  • 100
    • 0036083295 scopus 로고    scopus 로고
    • Evolving pathophysiologic models of functional gastrointestinal disorders
    • Mayer, E. A., and Collins, S. M. (2002). Evolving pathophysiologic models of functional gastrointestinal disorders. Gastroenterology 122, 2032-2048.
    • (2002) Gastroenterology , vol.122 , pp. 2032-2048
    • Mayer, E.A.1    Collins, S.M.2
  • 101
    • 0032894179 scopus 로고    scopus 로고
    • Review article: gender-related differences in functional gastrointestinal disorders
    • Mayer, E. A., Naliboff, B., Lee, O., Munakata, J., and Chang, L. (1999). Review article: gender-related differences in functional gastrointestinal disorders. Aliment. Pharmacol. Ther. 13(Suppl. 2), 65-69.
    • (1999) Aliment. Pharmacol. Ther. , vol.13 , Issue.SUPPL. 2 , pp. 65-69
    • Mayer, E.A.1    Naliboff, B.2    Lee, O.3    Munakata, J.4    Chang, L.5
  • 102
    • 33845722200 scopus 로고    scopus 로고
    • Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders
    • Mayer, E. A., Naliboff, B. D., and Craig, A. D. (2006). Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology 131, 1925-1942.
    • (2006) Gastroenterology , vol.131 , pp. 1925-1942
    • Mayer, E.A.1    Naliboff, B.D.2    Craig, A.D.3
  • 103
    • 34447629382 scopus 로고    scopus 로고
    • Physiology and neurobiology of stress and adaptation: central role of the brain
    • McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol. Rev. 87, 873-904.
    • (2007) Physiol. Rev. , vol.87 , pp. 873-904
    • McEwen, B.S.1
  • 105
    • 77953975713 scopus 로고    scopus 로고
    • Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome
    • doi:10.1371/journal.pone.0008226
    • McKernan, D. P., Nolan, A., Brint, E. K., O'Mahony, S. M., Hyland, N. P., Cryan, J. F., and Dinan, T. G. (2009). Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. PLoS ONE 4, e8226. doi:10.1371/journal.pone.0008226
    • (2009) PLoS ONE , vol.4
    • McKernan, D.P.1    Nolan, A.2    Brint, E.K.3    O'Mahony, S.M.4    Hyland, N.P.5    Cryan, J.F.6    Dinan, T.G.7
  • 106
    • 0034107656 scopus 로고    scopus 로고
    • Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention
    • Mertz, H., Morgan, V., Tanner, G., Pick-ens, D., Price, R., Shyr, Y., and Kessler, R. (2000). Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention. Gastroenterology 118, 842-848.
    • (2000) Gastroenterology , vol.118 , pp. 842-848
    • Mertz, H.1    Morgan, V.2    Tanner, G.3    Pick-ens, D.4    Price, R.5    Shyr, Y.6    Kessler, R.7
  • 107
    • 0037183764 scopus 로고    scopus 로고
    • 5-HT7 receptors are involved in mediating 5-HT-induced activation of rat primary afferent neurons
    • Meuser, T., Pietruck, C., Gabriel, A., Xie, G. X., Lim, K. J., and Pierce, P. P. (2002). 5-HT7 receptors are involved in mediating 5-HT-induced activation of rat primary afferent neurons. Life Sci. 71, 2279-2289.
    • (2002) Life Sci , vol.71 , pp. 2279-2289
    • Meuser, T.1    Pietruck, C.2    Gabriel, A.3    Xie, G.X.4    Lim, K.J.5    Pierce, P.P.6
  • 108
    • 0142122206 scopus 로고    scopus 로고
    • A novel water-soluble selective CRF1 receptor antagonist, NBI 35965 blunts stress-induced visceral hyperalgesia and colonic motor function in rats
    • Million, M., Grigoriadis, D. E., Sullivan, S., Crowe, P. D., McRoberts, J. A., Zhou, H., Saunders, P. R., Maillot, C., Mayer, E. A., and Taché, Y. (2003). A novel water-soluble selective CRF1 receptor antagonist, NBI 35965, blunts stress-induced visceral hyperalgesia and colonic motor function in rats. Brain Res. 985, 32-42.
    • (2003) Brain Res , vol.985 , pp. 32-42
    • Million, M.1    Grigoriadis, D.E.2    Sullivan, S.3    Crowe, P.D.4    McRoberts, J.A.5    Zhou, H.6    Saunders, P.R.7    Maillot, C.8    Mayer, E.A.9    Taché, Y.10
  • 109
    • 46349098219 scopus 로고    scopus 로고
    • Nuclear and extranuclear estrogen binding sites in the rat forebrain and auto-nomic medullary areas
    • Milner, T. A., Lubbers, L. S., Alves, S. E., and McEwen, B. S. (2008). Nuclear and extranuclear estrogen binding sites in the rat forebrain and auto-nomic medullary areas. Endocrinology 149, 3306-3312.
    • (2008) Endocrinology , vol.149 , pp. 3306-3312
    • Milner, T.A.1    Lubbers, L.S.2    Alves, S.E.3    McEwen, B.S.4
  • 110
    • 0030897376 scopus 로고    scopus 로고
    • Urocortin, a novel neuropeptide with anxiogenic-like properties
    • Moreau, J. L., Kilpatrick, G., and Jenck, F. (1997). Urocortin, a novel neuropeptide with anxiogenic-like properties. Neuroreport 8, 1697-1701.
    • (1997) Neuroreport , vol.8 , pp. 1697-1701
    • Moreau, J.L.1    Kilpatrick, G.2    Jenck, F.3
  • 111
    • 0033000181 scopus 로고    scopus 로고
    • Dif ferential distribution of urocortin-and corticotropin-releasing factor-like immunoreactivities in the rat brain
    • Morin, S. M., Ling, N., Liu, X. J., Kahl, S. D., and Gehlert, D. R. (1999). Dif ferential distribution of urocortin-and corticotropin-releasing factor-like immunoreactivities in the rat brain. Neuroscience 92, 281-291.
    • (1999) Neuroscience , vol.92 , pp. 281-291
    • Morin, S.M.1    Ling, N.2    Liu, X.J.3    Kahl, S.D.4    Gehlert, D.R.5
  • 112
    • 1942470635 scopus 로고    scopus 로고
    • Irritable bowel syndrome: a model of the brain-gut interactions
    • Mulak, A., and Bonaz, B. (2004). Irritable bowel syndrome: a model of the brain-gut interactions. Med. Sci. Monit. 10, RA55-RA62.
    • (2004) Med. Sci. Monit. , vol.10
    • Mulak, A.1    Bonaz, B.2
  • 113
    • 33645729806 scopus 로고    scopus 로고
    • Effect of 5-HT1 agonist (sumatriptan) on anorectal function in irritable bowel syndrome patients
    • Mulak, A., and Paradowski, L. (2006). Effect of 5-HT1 agonist (sumatriptan) on anorectal function in irritable bowel syndrome patients. World J. Gastroenterol. 12, 1591-1596.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 1591-1596
    • Mulak, A.1    Paradowski, L.2
  • 114
    • 34447530937 scopus 로고    scopus 로고
    • Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity
    • Myers, B., and Greenwood-Van, M. B. (2007). Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity. Am. J. Physiol. Gastroin-test. Liver Physiol. 292, G1622- G1629.
    • (2007) Am. J. Physiol. Gastroin-test. Liver Physiol. , vol.292
    • Myers, B.1    Greenwood-Van, M.B.2
  • 115
    • 84865422250 scopus 로고    scopus 로고
    • Role of anxiety in the pathophysiology of irritable bowel syndrome: importance of the amygdala
    • doi:10.3389/neuro.21.002.2009
    • Myers, B., and Greenwood-Van, M. B. (2009). Role of anxiety in the pathophysiology of irritable bowel syndrome: importance of the amygdala. Front. Neurosci. 3:47. doi:10.3389/neuro.21.002.2009
    • (2009) Front. Neurosci. , vol.3 , pp. 47
    • Myers, B.1    Greenwood-Van, M.B.2
  • 116
    • 77955275041 scopus 로고    scopus 로고
    • Elevated corticosterone in the amygdala leads to persis tent increases in anxiety-like behav ior and pain sensitivity
    • Myers, B., and Greenwood-Van, M. B. (2010). Elevated corticosterone in the amygdala leads to persis tent increases in anxiety-like behav ior and pain sensitivity. Behav. Brain Res. 214, 465-469.
    • (2010) Behav Brain Res , vol.214 , pp. 465-469
    • Myers, B.1    Greenwood-Van, M.B.2
  • 117
    • 79953267328 scopus 로고    scopus 로고
    • Sex steroids localized to the amygdala increase pain responses to visceral stimulation in rats
    • Myers, B., Schulkin, J., and Greenwood-Van, M. B. (2011). Sex steroids localized to the amygdala increase pain responses to visceral stimulation in rats. J. Pain. 12, 486-494.
    • (2011) J. Pain. , vol.12 , pp. 486-494
    • Myers, B.1    Schulkin, J.2    Greenwood-Van, M.B.3
  • 119
    • 0034999733 scopus 로고    scopus 로고
    • Cerebral activation in patients with irritable bowel syndrome and control subjects during rectosigmoid stimulation
    • Naliboff, B. D., Derbyshire, S. W., Munakata, J., Berman, S., Mandelkern, M., Chang, L., and Mayer, E. A. (2001). Cerebral activation in patients with irritable bowel syndrome and control subjects during rectosigmoid stimulation. Psy-chosom. Med. 63, 365-375.
    • (2001) Psy-chosom. Med. , vol.63 , pp. 365-375
    • Naliboff, B.D.1    Derbyshire, S.W.2    Munakata, J.3    Berman, S.4    Mandelkern, M.5    Chang, L.6    Mayer, E.A.7
  • 120
    • 85027944400 scopus 로고    scopus 로고
    • Reduced hippocampal glutamate-glutamine levels in irri table bowel syndrome: preliminary findings using magnetic resonance spectroscopy
    • Niddam, D. M., Tsai, S. Y., Lu, C L., Ko, C. W., and Hsieh, J. C. (2011). Reduced hippocampal glutamate-glutamine levels in irri table bowel syndrome: preliminary findings using magnetic resonance spectroscopy. Am. J. Gastroenterol. 106, 1503-1511.
    • (2011) Am. J. Gastroenterol. , vol.106 , pp. 1503-1511
    • Niddam, D.M.1    Tsai, S.Y.2    Lu, C.L.3    Ko, C.W.4    Hsieh, J.C.5
  • 121
    • 77949263115 scopus 로고    scopus 로고
    • Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions
    • Ohman, L., and Simren, M. (2010). Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat. Rev. Gastroenterol. Hepatol. 7, 163-173.
    • (2010) Nat. Rev. Gastroenterol. Hepatol. , vol.7 , pp. 163-173
    • Ohman, L.1    Simren, M.2
  • 125
    • 0027353096 scopus 로고
    • The role of corticotropin-releasing factor in the pathophys-iology of affective and anxiety disorders: laboratory and clinical studies
    • Owens, M. J., and Nemeroff, C. B. (1993). The role of corticotropin-releasing factor in the pathophys-iology of affective and anxiety disorders: laboratory and clinical studies. Ciba Found. Symp. 172, 296-308.
    • (1993) Ciba Found. Symp. , vol.172 , pp. 296-308
    • Owens, M.J.1    Nemeroff, C.B.2
  • 126
    • 33748131853 scopus 로고    scopus 로고
    • Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors
    • Pandey, S. C., Zhang, H., Roy, A., and Misra, K. (2006). Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors. J. Neurosci. 26, 8320-8331.
    • (2006) J. Neurosci. , vol.26 , pp. 8320-8331
    • Pandey, S.C.1    Zhang, H.2    Roy, A.3    Misra, K.4
  • 127
    • 0037185407 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice
    • Penalva, R. G., Flachskamm, C., Zimmermann, S., Wurst, W., Holsboer, F., Reul, J. M., and Linthorst, A. C. (2002). Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice. Neuroscience 109, 253-266.
    • (2002) Neuroscience , vol.109 , pp. 253-266
    • Penalva, R.G.1    Flachskamm, C.2    Zimmermann, S.3    Wurst, W.4    Holsboer, F.5    Reul, J.M.6    Linthorst, A.C.7
  • 128
    • 84861526537 scopus 로고    scopus 로고
    • Irritable bowel syndrome - an inflammatory disease involving mast cells
    • Philpott, H., Gibson, P., and Thien, F. (2011). Irritable bowel syndrome - an inflammatory disease involving mast cells. Asia Pac. Allergy 1, 36-42.
    • (2011) Asia Pac. Allergy. , vol.1 , pp. 36-42
    • Philpott, H.1    Gibson, P.2    Thien, F.3
  • 129
    • 80053563770 scopus 로고    scopus 로고
    • Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes
    • Piche, M., Bouin, M., Arsenault, M., Poitras, P., and Rainville, P. (2011). Decreased pain inhibition in irritable bowel syndrome depends on altered descending modulation and higher-order brain processes. Neuro-science 195, 166-175.
    • (2011) Neuro-science , vol.195 , pp. 166-175
    • Piche, M.1    Bouin, M.2    Arsenault, M.3    Poitras, P.4    Rainville, P.5
  • 130
    • 0022363376 scopus 로고
    • An assessment of the antinociceptive and aversive effects of stimulating identified sites in the rat brain
    • Prado,W.A.,and Roberts, M.H. (1985). An assessment of the antinociceptive and aversive effects of stimulating identified sites in the rat brain. Brain Res. 340, 219-228.
    • (1985) Brain Res , vol.340 , pp. 219-228
    • Prado, W.A.1    Roberts, M.H.2
  • 132
    • 43649107573 scopus 로고    scopus 로고
    • Brain imaging of visceral functions in healthy volunteers and IBS patients
    • Rapps, N., van Oudenhove, L., Enck, P., and Aziz, Q. (2008). Brain imaging of visceral functions in healthy volunteers and IBS patients. J. Psychosom. Res. 64, 599-604.
    • (2008) J. Psychosom. Res. , vol.64 , pp. 599-604
    • Rapps, N.1    van Oudenhove, L.2    Enck, P.3    Aziz, Q.4
  • 133
    • 0015861210 scopus 로고
    • A comparison of the pituitary adrenal activity elicited by electrical stimulation of preoptic, amygdaloid and hypothalamic sites in the ratbrain
    • Redgate, E. S., and Fahringer, E. E. (1973). A comparison of the pituitary adrenal activity elicited by electrical stimulation of preoptic, amygdaloid and hypothalamic sites in the ratbrain.Neuroendocrinology 12, 334-343.
    • (1973) Neuroendocrinology , vol.12 , pp. 334-343
    • Redgate, E.S.1    Fahringer, E.E.2
  • 134
    • 33947315932 scopus 로고    scopus 로고
    • Effects of neonatal maternal separation on neurochemicaland sensoryresponse to colonic distension in a rat model of irritable bowel syndrome
    • Ren, T. H., Wu, J., Yew, D., Ziea, E., Lao, L., Leung, W. K., Berman, B., Hu, P. J., and Sung, J. J. (2007). Effects of neonatal maternal separation on neurochemicaland sensoryresponse to colonic distension in a rat model of irritable bowel syndrome. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G849-G856.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.292
    • Ren, T.H.1    Wu, J.2    Yew, D.3    Ziea, E.4    Lao, L.5    Leung, W.K.6    Berman, B.7    Hu, P.J.8    Sung, J.J.9
  • 136
    • 27944463696 scopus 로고    scopus 로고
    • Interface of physical and emotional stress reg ulation through the endogenous opioid system and mu-opioid receptors Prog Neuropsy-chopharmacol
    • Ribeiro, S. C., Kennedy, S. E., Smith, Y. R., Stohler, C. S., and Zubieta, J. K. (2005). Interface of physical and emotional stress reg ulation through the endogenous opioid system and mu-opioid receptors Prog Neuropsy-chopharmacol. Biol. Psychiatry 29, 1264-1280.
    • (2005) Biol. Psychiatry. , vol.29 , pp. 1264-1280
    • Ribeiro, S.C.1    Kennedy, S.E.2    Smith, Y.R.3    Stohler, C.S.4    Zubieta, J.K.5
  • 137
    • 0036084392 scopus 로고    scopus 로고
    • Brain research in functional gastrointestinal disorders
    • Ringel,Y. (2002). Brain research in functional gastrointestinal disorders. J. Clin. Gastroenterol. 35(1 Suppl.), S23-S25.
    • (2002) J. Clin. Gastroenterol. , vol.35 , Issue.1 SUPPL.
    • Ringel, Y.1
  • 139
    • 70349816648 scopus 로고    scopus 로고
    • The neurology of the immune system: neural reflexes regulate immunity
    • Rosas-Ballina, M., and Tracey, K. J. (2009). The neurology of the immune system: neural reflexes regulate immunity. Neuron 64, 28-32.
    • (2009) Neuron , vol.64 , pp. 28-32
    • Rosas-Ballina, M.1    Tracey, K.J.2
  • 140
    • 2442549192 scopus 로고    scopus 로고
    • Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome
    • Sagami, Y., Shimada, Y., Tayama, J., Nomura, T., Satake, M., Endo, Y., Shoji, T., Karahashi, K., Hongo, M., and Fukudo, S. (2004). Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome. Gut 53, 958-964.
    • (2004) Gut , vol.53 , pp. 958-964
    • Sagami, Y.1    Shimada, Y.2    Tayama, J.3    Nomura, T.4    Satake, M.5    Endo, Y.6    Shoji, T.7    Karahashi, K.8    Hongo, M.9    Fukudo, S.10
  • 141
    • 0037162970 scopus 로고    scopus 로고
    • Colorectal distention induces hippocampal noradrenaline release in rats: an in vivo microdialysis study
    • Saito, K., Kanazawa, M., and Fukudo, S. (2002). Colorectal distention induces hippocampal noradrenaline release in rats: an in vivo microdialysis study. Brain Res. 947, 146-149.
    • (2002) Brain Res , vol.947 , pp. 146-149
    • Saito, K.1    Kanazawa, M.2    Fukudo, S.3
  • 142
    • 80955151296 scopus 로고    scopus 로고
    • Systematic review of modulators of benzodiazepine receptors in irritable bowel syndrome: is there hope?
    • Salari, P., and Abdollahi, M. (2011). Systematic review of modulators of benzodiazepine receptors in irritable bowel syndrome: is there hope? World J. Gastroenterol. 17, 4251-4257.
    • (2011) World J Gastroenterol , vol.17 , pp. 4251-4257
    • Salari, P.1    Abdollahi, M.2
  • 144
    • 0037169164 scopus 로고    scopus 로고
    • Peripheral corticotropin-releasing factor induces diarrhea in rats: role of CRF1 receptor in fecal watery excretion
    • Saunders, P. R., Maillot, C., Million, M., and Tache, Y. (2002). Peripheral corticotropin-releasing factor induces diarrhea in rats: role of CRF1 receptor in fecal watery excretion. Eur. J. Pharmacol. 435, 231-235.
    • (2002) Eur. J. Pharmacol. , vol.435 , pp. 231-235
    • Saunders, P.R.1    Maillot, C.2    Million, M.3    Tache, Y.4
  • 146
    • 0037435876 scopus 로고    scopus 로고
    • Stereotaxic localization of corticosterone to the amygdala enhances hypothalamo-pituitaryadrenal responses to behavioral stress
    • Shepard,J.D., Barron,K.W.,and Myers, D. A. (2003). Stereotaxic localization of corticosterone to the amygdala enhances hypothalamo-pituitaryadrenal responses to behavioral stress. Brain Res. 963, 203-213.
    • (2003) Brain Res , vol.963 , pp. 203-213
    • Shepard, J.D.1    Barron, K.W.2    Myers, D.A.3
  • 147
    • 2942547568 scopus 로고    scopus 로고
    • Effect of the 5HT1A receptor partial agonist bus-pirone on colorectal distension-induced pseudoaffective and behavioral responses in the female Wistar rat
    • Sivarao, D. V., Newberry, K., and Lodge, N. J. (2004). Effect of the 5HT1A receptor partial agonist bus-pirone on colorectal distension-induced pseudoaffective and behavioral responses in the female Wistar rat. Eur. J. Pharmacol. 494, 23-29.
    • (2004) Eur. J. Pharmacol. , vol.494 , pp. 23-29
    • Sivarao, D.V.1    Newberry, K.2    Lodge, N.J.3
  • 148
    • 8144230420 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphoryla-tion via ERK and PKC in the rat spinal cord
    • Slack, S. E., Pezet, S., McMahon, S. B., Thompson, S. W., and Mal-cangio, M. (2004). Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphoryla-tion via ERK and PKC in the rat spinal cord. Eur. J. Neurosci. 20, 1769-1778.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1769-1778
    • Slack, S.E.1    Pezet, S.2    McMahon, S.B.3    Thompson, S.W.4    Mal-cangio, M.5
  • 149
    • 0032805592 scopus 로고    scopus 로고
    • Neurophys-iological effects of intracerebroven-tricular administration of urocortin
    • Slawecki, C. J., Somes, C., Rivier, J. E., and Ehlers,C. L. (1999). Neurophys-iological effects of intracerebroven-tricular administration of urocortin. Peptides 20, 211-218.
    • (1999) Peptides , vol.20 , pp. 211-218
    • Slawecki, C.J.1    Somes, C.2    Rivier, J.E.3    Ehlers, C.L.4
  • 153
    • 34447136135 scopus 로고    scopus 로고
    • Recent advances in understanding the role of serotonin in gastrointestinal motility in functional bowel disorders: alterations in 5-HT signalling and metabolism in human disease
    • Spiller, R. (2007). Recent advances in understanding the role of serotonin in gastrointestinal motility in functional bowel disorders: alterations in 5-HT signalling and metabolism in human disease. Neurogastroenterol. Motil. 19(Suppl. 2), 25-31.
    • (2007) Neurogastroenterol. Motil. , vol.19 , Issue.SUPPL. 2 , pp. 25-31
    • Spiller, R.1
  • 154
    • 70350569462 scopus 로고    scopus 로고
    • Infection, inflammation, and the irritable bowel syndrome
    • Spiller, R., and Garsed, K. (2009). Infection, inflammation, and the irritable bowel syndrome. Dig. Liver Dis. 41, 844-849.
    • (2009) Dig. Liver Dis. , vol.41 , pp. 844-849
    • Spiller, R.1    Garsed, K.2
  • 156
    • 57649183357 scopus 로고    scopus 로고
    • From Hans Selye's discovery of biological stress to the identification of corticotropin-releasing factor signaling pathways: implication in stress-related functional bowel diseases
    • Tache, Y., and Brunnhuber, S. (2008). From Hans Selye's discovery of biological stress to the identification of corticotropin-releasing factor signaling pathways: implication in stress-related functional bowel diseases. Ann. N. Y. Acad. Sci. 1148, 29-41.
    • (2008) Ann. N. Y. Acad. Sci , vol.1148 , pp. 29-41
    • Tache, Y.1    Brunnhuber, S.2
  • 157
    • 67849089070 scopus 로고    scopus 로고
    • A role for corticotropin-releasing factor in functional gastrointestinal disorders
    • Tache, Y., Kiank, C., and Stengel, A. (2009). A role for corticotropin-releasing factor in functional gastrointestinal disorders. Curr. Gastroenterol. Rep. 11, 270-277.
    • (2009) Curr. Gastroenterol. Rep. , vol.11 , pp. 270-277
    • Tache, Y.1    Kiank, C.2    Stengel, A.3
  • 158
    • 0036961118 scopus 로고    scopus 로고
    • Role of cor-ticotropin releasing factor receptor subtype 1instress-related functional colonic alterations: implications in irritable bowel syndrome
    • Tache, Y., Martinez, V., Million, M., and Maillot, C. (2002). Role of cor-ticotropin releasing factor receptor subtype 1instress-related functional colonic alterations: implications in irritable bowel syndrome. Eur. J. Surg. 168 (Suppl. 1), 16-22.
    • (2002) Eur. J. Surg. , vol.168 , Issue.SUPPL. 1 , pp. 16-22
    • Tache, Y.1    Martinez, V.2    Million, M.3    Maillot, C.4
  • 159
    • 2442539352 scopus 로고    scopus 로고
    • CRF1 receptor signaling pathways are involved in stress-related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome
    • Tache, Y., Martinez, V., Wang, L., and Million, M. (2004). CRF1 receptor signaling pathways are involved in stress-related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome. Br. J. Pharmacol. 141, 1321-1330.
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 1321-1330
    • Tache, Y.1    Martinez, V.2    Wang, L.3    Million, M.4
  • 160
    • 33746162460 scopus 로고    scopus 로고
    • A controlled crossover study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome
    • Tack, J., Broekaert, D., Fischler, B., van Oudenhove, L., Gevers, A. M., and Janssens, J. (2006). A controlled crossover study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome. Gut 55, 1095-1103.
    • (2006) Gut , vol.55 , pp. 1095-1103
    • Tack, J.1    Broekaert, D.2    Fischler, B.3    van Oudenhove, L.4    Gevers, A.M.5    Janssens, J.6
  • 161
    • 0034070874 scopus 로고    scopus 로고
    • Influence of sumatriptan on gastric fun-dus tone and on the perception of gastric distension in man
    • Tack, J., Coulie, B., Wilmer, A., Andri-oli, A., and Janssens, J. (2000). Influence of sumatriptan on gastric fun-dus tone and on the perception of gastric distension in man. Gut 46, 468-473.
    • (2000) Gut , vol.46 , pp. 468-473
    • Tack, J.1    Coulie, B.2    Wilmer, A.3    Andri-oli, A.4    Janssens, J.5
  • 162
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O., and Akira, S. (2010). Pattern recognition receptors and inflammation. Cell 140, 805-820.
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 163
    • 0034124615 scopus 로고    scopus 로고
    • Irritable bowel syndrome in general practice: prevalence, characteristics, and referral
    • Thompson, W. G., Heaton, K. W., Smyth, G. T., and Smyth, C. (2000). Irritable bowel syndrome in general practice: prevalence, characteristics, and referral. Gut 46, 78-82.
    • (2000) Gut , vol.46 , pp. 78-82
    • Thompson, W.G.1    Heaton, K.W.2    Smyth, G.T.3    Smyth, C.4
  • 164
    • 84855354656 scopus 로고    scopus 로고
    • Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study
    • Tillisch, K., Labus, J., Nam, B., Bueller, J., Smith, S., Suyenobu, B., Sif-fert, J., McKelvy, J., Naliboff, B., and Mayer, E. (2012). Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study. Aliment. Pharmacol. Ther. 35, 360-367.
    • (2012) Aliment. Pharmacol. Ther. , vol.35 , pp. 360-367
    • Tillisch, K.1    Labus, J.2    Nam, B.3    Bueller, J.4    Smith, S.5    Suyenobu, B.6    Sif-fert, J.7    McKelvy, J.8    Naliboff, B.9    Mayer, E.10
  • 165
    • 78650505214 scopus 로고    scopus 로고
    • Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome
    • Tillisch, K., Mayer, E. A., and Labus, J. S. (2011). Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology 140, 91-100.
    • (2011) Gastroenterology , vol.140 , pp. 91-100
    • Tillisch, K.1    Mayer, E.A.2    Labus, J.S.3
  • 166
    • 25444499721 scopus 로고    scopus 로고
    • Sex specific alterations in autonomic function among patients with irritable bowel syndrome
    • Tillisch, K., Mayer, E. A., Labus, J. S., Stains, J., Chang, L., and Naliboff, B. D. (2005). Sex specific alterations in autonomic function among patients with irritable bowel syndrome. Gut 54, 1396-1401.
    • (2005) Gut , vol.54 , pp. 1396-1401
    • Tillisch, K.1    Mayer, E.A.2    Labus, J.S.3    Stains, J.4    Chang, L.5    Naliboff, B.D.6
  • 167
    • 77952403817 scopus 로고    scopus 로고
    • Neonatal maternal separation elevates thalamic corticotrophin releasing factor type 1 receptor expression response to colonic distension in rat
    • Tjong, Y. W., Ip, S. P., Lao, L., Wu, J., Fong, H. H., Sung, J. J., Berman, B., and Che, C. T. (2010). Neonatal maternal separation elevates thalamic corticotrophin releasing factor type 1 receptor expression response to colonic distension in rat. Neuro Endocrinol. Lett. 31, 215-220.
    • (2010) Neuro Endocrinol. Lett. , vol.31 , pp. 215-220
    • Tjong, Y.W.1    Ip, S.P.2    Lao, L.3    Wu, J.4    Fong, H.H.5    Sung, J.J.6    Berman, B.7    Che, C.T.8
  • 169
    • 34548192035 scopus 로고    scopus 로고
    • Corticotropin-releasing factor receptor 1-deficient mice show decreased anxiety and colonic sensitivity
    • Trimble, N., Johnson, A. C., Foster, A., and Greenwood-Van, M. B. (2007). Corticotropin-releasing factor receptor 1-deficient mice show decreased anxiety and colonic sensitivity. Neurogastroenterol. Motil. 19, 754-760.
    • (2007) Neurogastroenterol. Motil. , vol.19 , pp. 754-760
    • Trimble, N.1    Johnson, A.C.2    Foster, A.3    Greenwood-Van, M.B.4
  • 170
    • 34548147061 scopus 로고    scopus 로고
    • Long-term colonic hyper-sensitivity in adult rats induced by neonatal unpredictable vs predictable shock
    • Tyler, K., Moriceau, S., Sullivan, R. M., and Greenwood-Van, M. B. (2007). Long-term colonic hyper-sensitivity in adult rats induced by neonatal unpredictable vs predictable shock. Neurogastroenterol. Motil. 19, 761-768.
    • (2007) Neurogastroenterol. Motil. , vol.19 , pp. 761-768
    • Tyler, K.1    Moriceau, S.2    Sullivan, R.M.3    Greenwood-Van, M.B.4
  • 171
    • 0019782980 scopus 로고
    • Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of cor-ticotropin and beta-endorphin
    • Vale, W., Spiess, J., Rivier, C., and Riv-ier, J. (1981). Characterization of a 41-residue ovine hypothalamic pep-tide that stimulates secretion of cor-ticotropin and beta-endorphin. Science 213, 1394-1397.
    • (1981) Science , vol.213 , pp. 1394-1397
    • Vale, W.1    Spiess, J.2    Rivier, C.3    Rivier, J.4
  • 172
    • 14644442955 scopus 로고    scopus 로고
    • Peptides that fine-tune the serotonin system
    • Valentino, R. J., and Commons, K. G. (2005). Peptides that fine-tune the serotonin system. Neuropeptides 39, 1-8.
    • (2005) Neuropeptides , vol.39 , pp. 1-8
    • Valentino, R.J.1    Commons, K.G.2
  • 174
    • 77950937264 scopus 로고    scopus 로고
    • Exposure of the amygdala to elevated levels of corti-costerone alters colonic motility in response to acute psychological stress
    • Venkova, K., Johnson, A. C., Myers, B., and Greenwood-Van, M. B. (2010). Exposure of the amygdala to elevated levels of corti-costerone alters colonic motility in response to acute psychological stress. Neuropharmacology 58, 1161-1167.
    • (2010) Neuropharmacology , vol.58 , pp. 1161-1167
    • Venkova, K.1    Johnson, A.C.2    Myers, B.3    Greenwood-Van, M.B.4
  • 175
    • 53049104302 scopus 로고    scopus 로고
    • Reversal of inflammatory and noninflammatory visceral pain by central or peripheral actions of sumatriptan
    • Vera-Portocarrero, L. P., Ossipov, M. H., King, T., and Porreca, F. (2008). Reversal of inflammatory and noninflammatory visceral pain by central or peripheral actions of sumatriptan. Gastroenterology 135, 1369-1378.
    • (2008) Gastroenterology , vol.135 , pp. 1369-1378
    • Vera-Portocarrero, L.P.1    Ossipov, M.H.2    King, T.3    Porreca, F.4
  • 177
    • 70749155622 scopus 로고    scopus 로고
    • Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome
    • Videlock, E. J., Adeyemo, M., Licudine, A., Hirano, M., Ohning, G., Mayer, M., Mayer, E. A., and Chang, L. (2009). Childhood trauma is associated with hypothalamic-pituitary-adrenal axis responsiveness in irritable bowel syndrome. Gastroenterol-ogy 137, 1954-1962.
    • (2009) Gastroenterology , vol.137 , pp. 1954-1962
    • Videlock, E.J.1    Adeyemo, M.2    Licudine, A.3    Hirano, M.4    Ohning, G.5    Mayer, M.6    Mayer, E.A.7    Chang, L.8
  • 178
    • 7244223149 scopus 로고    scopus 로고
    • Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls
    • Wilder-Smith, C. H., Schindler, D., Lovblad, K., Redmond, S. M., and Nirkko, A. (2004). Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls. Gut 53, 1595-1601.
    • (2004) Gut , vol.53 , pp. 1595-1601
    • Wilder-Smith, C.H.1    Schindler, D.2    Lovblad, K.3    Redmond, S.M.4    Nirkko, A.5
  • 179
    • 72549115234 scopus 로고    scopus 로고
    • Adrenergic stimulation mediates visceral hypersensitiv-ity to colorectal distension following heterotypic chronic stress
    • Winston, J. H., Xu, G. Y., and Sarna, S. K. (2010). Adrenergic stimulation mediates visceral hypersensitivity to colorectal distension following heterotypic chronic stress. Gastroen-terology 138, 294-304.
    • (2010) Gastroenterology , vol.138 , pp. 294-304
    • Winston, J.H.1    Xu, G.Y.2    Sarna, S.K.3
  • 180
    • 84859575178 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor contributes to abdominal pain in irritable bowel syndrome
    • Yu, Y. B., Zuo, X. L., Zhao, Q. J., Chen, F. X., Yang, J., Dong, Y. Y., Wang, P., and Li, Y.Q. (2012). Brain-derived neurotrophic factor contributes to abdominal pain in irritable bowel syndrome. Gut 61, 685-694.
    • (2012) Gut , vol.61 , pp. 685-694
    • Yu, Y.B.1    Zuo, X.L.2    Zhao, Q.J.3    Chen, F.X.4    Yang, J.5    Dong, Y.Y.6    Wang, P.7    Li, Y.Q.8
  • 181
    • 0030749030 scopus 로고    scopus 로고
    • Peripheral-type benzodi-azepine receptors
    • Zisterer, D. M., and Williams, D. C. (1997). Peripheral-type benzodi-azepine receptors. Gen. Pharmacol. 29, 305-314.
    • (1997) Gen. Pharmacol. , vol.29 , pp. 305-314
    • Zisterer, D.M.1    Williams, D.C.2
  • 182
    • 37249051304 scopus 로고    scopus 로고
    • Expression and role of 5-HT7 receptor in brain and intestine in rats with irritable bowel syndrome
    • Zou, B. C., Dong, L., Wang, Y., Wang, S. H., and Cao, M. B. (2007). Expression and role of 5-HT7 receptor in brain and intestine in rats with irritable bowel syndrome. Chin. Med. J. 120, 2069-2074.
    • (2007) Chin. Med. J. , vol.120 , pp. 2069-2074
    • Zou, B.C.1    Dong, L.2    Wang, Y.3    Wang, S.H.4    Cao, M.B.5


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