The 5-HT3 receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat

Gut

Volumn 46, Issue 4, 2000, Pages 474-480

  Kozlowski, C M ^a   Green, A ^a   Grundy, D ^b   Boissonade, F M ^c   Bountra, C ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

5 HT3; Alosetron; Colorectal distention; Fos; Pseudoaffective reflex; Spinal cord

Indexed keywords

ALOSETRON; PROTEIN C FOS; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SODIUM CHLORIDE;

ABDOMINAL DISTENSION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON DILATATION; COLORECTAL DISEASE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; LUMBOSACRAL SPINE; MALE; NOCICEPTION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; SPINAL CORD NERVE CELL; VISCERA;

ANIMALS; BALLOON DILATATION; BLOOD PRESSURE; CARBOLINES; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; GENES, FOS; MALE; RATS; RATS, WISTAR; RECTUM; SEROTONIN ANTAGONISTS; SPINAL CORD;

EID: 0034066325     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.46.4.474     Document Type: Article

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