Irritable bowel syndrome: A model of the brain-gut interactions

Medical Science Monitor

Volumn 10, Issue 4, 2004, Pages

  Mulak, Agata ^a   Bonaz, Bruno ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Brain gut axis; Irritable bowel syndrome; Neuroimmune interactions

Indexed keywords

AUTONOMIC DYSFUNCTION; BEHAVIOR; BRAIN FUNCTION; COGNITION; DIGESTIVE SYSTEM INFLAMMATION; DISEASE ASSOCIATION; EMOTION; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL SECRETION; HEALTH BEHAVIOR; HEALTH STATUS; HUMAN; IMMUNE RESPONSE; INTESTINE INNERVATION; IRRITABLE COLON; NERVE CONDUCTION; NERVE TRACT; NEUROENDOCRINE SYSTEM; NEUROIMAGING; NEUROIMMUNOLOGY; NEUROPHYSIOLOGY; REVIEW; SEX DIFFERENCE; SOCIAL PSYCHOLOGY; STRESS; TREATMENT OUTCOME;

BRAIN; EMOTIONS; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL MOTILITY; HUMANS; INTESTINES; IRRITABLE BOWEL SYNDROME;

EID: 1942470635     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (65)

1. Drossman DA, Corazziari E, Halley NJ et al: A multinational consensus document on functional gastrointestinal disorders. Gut. 1999; 45(Suppl II): II1-II81
2. American Gastroenterological Association Medical Position Statement: Irritable Bowel Syndrome (document approved by the Clinical Practise Committee and the AGA Governing Board). Gastroenterology, 2002; 123: 2105-7
3. Mayer EA, Naliboff B D, Chang L: Basic pathophysiologic mechanisms in irritable bowel syndrome. Dig Dis, 2001; 19: 212-18
4. Black PH: Stress and the inflammatory response: A review of neurogenic inflammation. Brain Behav Immun, 2002; 16: 622-53
5. Mayer EA, Naliboff BD, Chang L, Coutinho SV: Stress and irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol, 2001; 280: G519-24
6. Mayer EA, Collins AM: Evolving pathophysiologic models of functional gastrointestinal disorders. Gastroenterology, 2002; 122: 2032-48
7. Hart A, Kamm MA: Review article: mechanisms of initiation and perpetuation of gut inflammation by stress. Aliment Pharmacol Ther, 2002; 16: 2017-28
8. nd ed. Milano: Messaggi, 2000, p. 143-51
9. nd ed. McLean: Degon and Associates, 2000, p. 31-90
10. Azpiroz F: Hypersensitivity in functional gastrointestinal disorders. Gut, 2002;51(Suppl 1): i25-i28
11. Bonaz B, Riviere PJ, Sinniger V et al: Fedotozine, a kappa-opioid agonist, prevents spinal and supra-spinal Fos expression induced by a noxious visceral stimulus in the rat. Neurogastroenterol Motil, 2000; 12: 13547
12. Ward SM: Interstitial cells of Cajal in enteric neurotransmission. Gut, 2000; 47(Suppl IV): iv40-iv43
13. Tougas G: The autonomic nervous system in functional bowel disorders. Gut, 2000; 47(Suppl IV): iv78-iv80
14. Aggarwal A, Cutts TF, Abell AL et al: Predominant symptoms in irritable bowel syndrome correlate with specific autonomic nervous system abnormalities. Gastroenterolgy, 1994; 106: 945-50
15. Heitkemper M, Jarret M, Cain KC et al: Autonomic nervous system in women with irritable bowel syndrome. Dig Dis Sci, 2001; 46: 1276-84
16. Elsenbruch S, Orr WC: Diarrhea- and constipation-predominant IBS patients in postprandrial autonomic and cortisol responses. Am J Gastroenterol, 2001; 96: 460-66
17. Straub RH, Antoniou E, Zeuner M et al: Association of autonomic nervous hyperreflexia and systemic inflammation in patients with Crohn's disease and ulcerative colitis. J Neuroimmunol, 1997; 80: 149-57
18. Orr WC, Crowell MD, Lin B et al: Sleep and gastric function in irritable bowel syndrome: derailing the brain-gut axis. Gut, 1997; 41: 390-93
19. Thompson JJ, Elsenbruch S, Hatnish MJ, Orr WC. Autonomic functioning during REM sleep differentiates IBS symptom subgroups. Am J Gastroenterol, 2002; 97: 147-53
20. Cook IJ, Eden A, Collins SM: Patients with irritable bowel syndrome have greater pain tolerance than normal subjects. Gastroenterology, 1987; 93: 727-33
21. Gupta V, Sheffield D, Verne GN: Evidence for autonomic dysregulation in irritable bowel syndrome. Dig Dis Sci, 2002; 47: 1716-22
22. Chang L, Berman S, Mayer EA et al: Brain responses to visceral and somatic stimuli in patients with irritable bowel syndrome with and without fibromyalgia. Am J Gastroenterol, 2003; 98: 1354-61
23. Jarret ME, Burr RL et al: Anxiety and depression are related to autonomic nervous system function in women with irritable bowel syndrome. Dig Dis Sci, 2003; 48: 386-94
24. Mazzon E, Sturniolo GC, Puzzolo D et al: Effect of stress on the paracellular barrier in the rat ileum. Gut, 2002; 51: 507-13
25. Collins SM: Stress and the gastrointestinal tract IV. Modulation of intestinal inflammation by stress: basic mechanism and clinical relevance. Am J Physiol Gastrointest Liver Physiol, 2001; 280: G315-18
26. Santos J, Yang PC, Soderholm J D et al: Role of mast cells in chronic stress-induced colonic epithelial barrier dysfunction in the rat. Gut, 2001; 48: 630-36
27. Neal KR, Hebden J, Spiller R: Prevalence of gastrointestinal symptoms six month after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: Postal survey of patients. BMJ, 1997; 314: 779-82
28. Isgar B, Harman M, Kaye MD, Whorwell PJ; Symptoms of irritable bowel syndrome in ulcerative colitis in remission. Gut, 1983; 24: 190-92
29. O'Sullivan M, Clayton N, Breslin NP et al: Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil, 2000; 12: 449-57
30. Spiller RC, Jenkins D, Thornley JP et al: Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut, 2000; 47: 804-11
31. Gwee KA, Collins SM, Read NW et al: Increased rectal mucosal expression of interleukin 1beta in recent acquired post-infectious irritable bowel syndrome. Gut, 2003; 53: 523-26
32. Törnblom H, Lindberg G, Nyberg B, Veress B: Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Gastroenterology, 2002; 123: 1978-79
33. Bueno L, Fioramonti J: Visceral perception: inflammatory and non-inflammatory mediators. Gut, 2002; 51(Suppl 1): i19-i23
34. Gui XY: Mast cells: a possible link between psychological stress, enteric infection, food allergy and gut hypersensitivity in the irritable bowel syndrome. J Gastroenterol Hepatol, 1998; 13: 980-89
35. Gwee KA, Leon YL, Graham C et al: The role of psychological and biological factors in postinfective gut dysfunction. Gut, 1999; 44:400-6
36. Elenkov IJ, Wilder RL, Chrousos GP, Vizi ES: The sympathetic nerve-an integrative interface between two supersystems: the brain and the immune system. Pharmacol Rev, 2000; 52: 595-638
37. Wood JD: Neuropathophysiology of irritable bowel syndrome. J Clin Gastroenterol, 2002; 35(Suppl 1): S11-22
38. Chrousos MD: Stress, chronic inflammation, and emotional and physical well-being: concurrent effects and chronic sequelae. J Allergy Clin Immunol, 2000; 106: S275-291
39. nd ed. Philadelphia: Lippincott Co, 1995, p. 620-37
40. Monnikes H, Tebbe JJ, Hidebrandt M et al: Role of stress in functional gastrointestinal disorders. Evidence for stress-induced alteration in gastrointestinal motility and sensitivity. Dig Dis, 2001; 19: 201-11
41. Bonaz B, Rivest S: Effect of a chronic stress on CRF neuronal activity and expression of its type 1 receptor in the rat brain. Am J Physiol, 1998; 275: R1438-49
42. Tache Y, Martinez V, Million M, Wang L: Stress and the gastrointestinal tract III. Stress-related alterations of gut motor function: role of brain corticotropin-releasing factor receptors. Am J Physiol Gastrointest Liver Physiol, 2001; 280: G173-77
43. Tache Y, Monnikes H, Bonaz B, Rivier J: Role of CRF in stress-related alterations of gastric and colonic motor function. Ann NY Acad Sci, 1993; 697: 233-43
44. Bonaz B, Tache Y: Water-avoidance stress-induced c-fos expression in the rat brain and stimulation of fecal output: role of corticotropin-releasing factor. Brain Res, 1994; 641: 21-28
45. Barquist E, Bonaz B, Martinez V et al: Neuronal pathways involved in abdominal surgery-induced gastric ileus in rats. Am J Physiol, 1996; 270: R888-94
46. Radulovic J, Ruhmann A, Liepold T, Spiess J: Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2. J Neurosci, 1999; 19: 5016-25
47. Nemeroff CB: New directions in the development of antidepressants: the interface of neurobiology and psychiatry. Hum Psychopharmacol, 2002; 17(Suppl 1): S13-16
48. nd ed. McLean: Degon and Associates, 2000, p. 157-245
49. Drossman DA, Li Z, Leserman Z et al: Health status by gastrointestinal diagnosis and abuse history. Gastroenterology, 1996; 113: 823-33
50. Drossman DA: Irritable bowel syndrome and sexual/physical abuse history. Eur J Gastroenterol Hepat, 1997; 9: 327-30
51. Garakani A, Win T, Virk S et al: Comorbidity of irritable bowel syndrome in psychiatric patients: a review. Am J Ther, 2003; 10: 61-67
52. Whitehead WE, Palsson O, Jones KR: Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications? Gastroenterology, 2002; 122: 1140-56
53. Prior A, Colgan SM, Whorwell PJ: Changes in rectal sensitivity after hypnotherapy with irritable bowel syndrome. Gut, 1990; 31: 896-98
54. Houghton LA, Calvert EL, Jackson NA et al: Visceral sensation and emotion: a study using hypnosis. Gut, 2002; 51: 701-4
55. Poitras P, Riberdy Poitras M et al: Evolution of visceral sensitivity in patients with irritable bowel syndrome. Dig Dis Sci, 2002; 47: 914-20
56. Drossman DA: Review article: an integrated approach to the irritable bowel syndrome. Aliment Pharmacol Ther, 1999; 13(Suppl 2): 3-14
57. Aziz Q,Thompson AG: Brain-gut axis in health and disease. Gastroenterology, 1999; 114: 559-78
58. Ringel Y: Brain research in functional gastrointestinal disorders. J Clin Gastroenterol, 2002; 35: S23-25
59. Silverman DH, Munakata JA, Ennes H et al: Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology, 1997; 112: 64-72
60. Mertz H, Morgan V, Tanner G et al: Regional cerebral activation in irritable bowel syndrome and control subjects with painful and non-painful rectal distension. Gastroenterology, 2000; 118: 842-48
61. Baciu MV, Bonaz BL, Papillon E et al: Central processing of rectal pain: a functional MR imaging study. Am J Neuroradiol, 1999; 20: 1920-24
62. Bonaz B, Baciu M, Papillon E et al: Central processing of rectal pain in patients with irritable bowel syndrome: an fMRI study. Am J Gastroenterol, 2002, 97: 654-61
63. Drossman DA, Ringel Y, Vogt BA et al: Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome. Gastroenterology, 2003; 124: 754-61
64. Berman S, Munakata J, Naliboff BD et al: Gender differences in regional brain response to visceral pressure in IBS patients. Eur J Pain, 2000; 4: 157-72
65. Naliboff BD, Berman S, Chang L et al: Sex-related differences in IBS patients: central processing of visceral stimuli. Gastroenterology, 2003; 124: 1738-47