Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: An in vivo microdialysis study in mutant mice

Neuroscience

Volumn 109, Issue 2, 2002, Pages 253-266

  Pealva, R G ^a   Flachskamm, C ^a   Zimmermann, S ^a   Wurst, W ^a   Holsboer, F ^a   Reul, J M H M ^a   Linthorst, A C E ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

5 hydroxyindoleacetic acid; Behaviour; Corticotropin releasing hormone; Forced swimming; Free corticosterone; Stress

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN LEVEL; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENOTYPE; HETEROZYGOSITY; HIPPOCAMPUS; HOMOZYGOSITY; HORMONE RECEPTOR INTERACTION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MICRODIALYSIS; MOUSE; MOUSE MUTANT; NEUROTRANSMISSION; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; STRESS; SWIMMING;

ANIMALS; BEHAVIOR, ANIMAL; CIRCADIAN RHYTHM; CORTICOTROPIN-RELEASING HORMONE; CORTISONE; EXTRACELLULAR SPACE; HIPPOCAMPUS; HYDROXYINDOLEACETIC ACID; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MICE; MICE, MUTANT STRAINS; MICRODIALYSIS; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SEROTONIN; STRESS; SWIMMING; SYNAPTIC TRANSMISSION;

EID: 0037185407     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00475-4     Document Type: Article

References (71)

1. The role of corticotropin-releasing factor in depression and anxiety disorders
2. Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: Dialysate serotonin reflects neuronal release
3. Corticosterone regulation of tryptophan hydroxylase in midbrain of the rat
4. Do centrally administered neuropeptides access cognate receptors? An analysis in the central corticotropin-releasing factor system
5. Expression of an mdr gene is associated with a new form of resistance to dexamethasone-induced apoptosis
6. Toward a unified theory of serotonin dysregulation in eating and related disorders
7. Effects of ganglionic blocking agents on behavioral responses to centrally administered CRF
8. Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty
9. Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test
10. Corticotropin-releasing factor: Actions on the sympathetic nervous system and metabolism
11. 1 receptor mRNA expression
12. Altered basal locomotor activity and improved motor coordination in corticotropin-releasing factor receptor 1-deficient mice
13. Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2
14. In vivo evidence that 5-hydroxytryptamine (5-HT) neuronal firing and release are not necessarily correlated with 5-HT metabolism
15. Corticotropin-releasing factor immunoreactivity is widely distributed within the central nervous system of the rat: An immunohistochemical study
16. Activation of the locus coeruleus noradrenergic system by intracoerulear microinfusion of corticotropin-releasing factor - Effects on discharge rate, cortical norepinephrine levels and cortical electroencephalographic activity
17. Corticotropin-releasing factor receptors: Physiology, pharmacology, biochemistry and role in central nervous system and immune disorders
18. The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress
19. Endogenous regulation of serotonin release in the hamster suprachiasmatic nucleus
20. Physiological and behavioral responses to corticotropin-releasing factor administration - Is CRF a mediator of anxiety or stress responses
21. Serotonergic mechanisms in anxiety
22. How important is the synthesis of brain 5-hydroxytryptamine in the physiological control of its central function?
23. The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety
24. Structure and function of the brain serotonin system
25. Eating disorders and depression: Is there a serotonin connection?
26. The behavioural effects of corticotropin-releasing factor-related peptides in rats
27. Regional differences in the effects of forced swimming on extracellular levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid
28. Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus
29. Lack of effect of various endocrine manipulations on tryptophan hydroxylase activity of individual nuclei of the hypothalamus, limbic system, and midbrain of the rat
30. Corticotropin-releasing factor, norepinephrine, and stress
31. A role for corticotropin releasing factor and urocortin in behavioral responses to stressors
32. Distribution of urocortin-like immunoreactivity in the central nervous system of the rat
33. Serotonin neurochemistry revisited: A new look at some old axioms
34. Corticotropin-releasing factor stimulates catecholamine release in hypothalamus and prefrontal cortex in freely moving rats as assessed by microdialysis
35. The hypothalamic-pituitary-adrenal axis in anorexia nervosa
36. Glucocorticoid receptor impairment alters CNS responses to a psychological stressor: An in vivo microdialysis study in transgenic mice
37. Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature
38. Long-term intracerebroventricular infusion of corticotropin-releasing hormone alters neuroendocrine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge
39. Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: An in vivo microdialysis study
40. Effect of forced swimming on hippocampal serotonergic neurotransmission in the rat: Role of corticotropin-releasing hormone
41. Corticotropin-releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus: Evidence for activation of a topographically organized mesolimbocortical serotonergic system
42. The serotonin hypothesis of major depression
43. Neuronal release of serotonin in the cerebellum of behaving rats: An in vivo microdialysis study
44. Urocortin, a novel neuropeptide with anxiogenic-like properties
45. Regulation of 5-hydroxytryptamine metabolism in mouse brain by adrenal glucocorticoids
46. Physiology and pharmacology of corticotropin-releasing factor
47. Distribution of corticotropin-releasing factor in rat brain
48. The central distribution of a corticotropin-releasing factor (CRF)-binding protein predicts multiple sites and modes of interaction with CRF
49. Effects of corticotropin-releasing factor on brain serotonergic activity
50. The brain mineralocorticoid receptor: Greedy for ligand, mysterious in function
51. Central administration of corticotropin-releasing hormone profoundly stimulates rat hippocampal serotonergic neurotransmission and behavioral activity: No effect of adrenalectomy
52. Inhibition of adrenocorticotropic hormone secretion in the rat by immunoneutralization of corticotropin-releasing factor
53. Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin
54. The functions of corticosteroid-binding globulin and sex hormone-binding globulin: Recent advances
55. A critical review of 5-HT brain microdialysis and behavior
56. Changes in forebrain serotonin at the light-dark transition: Correlation with behaviour
57. CP-154,526: A potent and selective nonpeptide antagonist of corticotropin releasing factor receptors
58. Increases in the activity of tryptophan hydroxylase from rat cortex and midbrain in response to acute or repeated sound stress are blocked by adrenalectomy and restored by dexamethasone treatment
59. Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
60. Corticotropin-releasing hormone receptor subtypes and emotion
61. Corticotropin releasing factor produces behavioural activation in rats
62. Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: An immunohistochemical study
63. Glucocorticoids as a regulatory factor for brain tryptophan hydroxylase
64. Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
65. CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation
66. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
67. Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus
68. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
69. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH
70. Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze
71. Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated