Altered Brain Structure in Irritable Bowel Syndrome: Potential Contributions of Pre-Existing and Disease-Driven Factors

Gastroenterology

Volumn 138, Issue 5, 2010, Pages 1783-1789

  Blankstein, Udi ^a,b   Chen, Jerry ^a,b   Diamant, Nicholas E ^c   Davis, Karen D ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Gray Matter; Irritable Bowel Syndrome; Magnetic Resonance Imaging; Pain

Indexed keywords

ADULT; ARTICLE; BRAIN REGION; CHRONIC PAIN; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GRAY MATTER; HUMAN; HYPOTHALAMUS; INSULA; IRRITABLE COLON; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 77951667119     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.12.043     Document Type: Article

References (34)

1. Drossman D.A. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 130 (2006) 1377-1390
2. Rapps N., van Oudenhove L., Enck P., et al. Brain imaging of visceral functions in healthy volunteers and IBS patients. J Psychosom Res 64 (2008) 599-604
3. Mayer E.A., Naliboff B.D., and Craig A.D. Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders. Gastroenterology 131 (2006) 1925-1942
4. Knowles C.H., and Aziz Q. Basic and clinical aspects of gastrointestinal pain. Pain 141 (2009) 191-209
5. Mayer E.A., Naliboff B.D., Chang L., et al. V. Stress and irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 280 (2001) G519-G524
6. Tache Y., and Bonaz B. Corticotropin-releasing factor receptors and stress-related alterations of gut motor function. J Clin Invest 117 (2007) 33-40
7. Hazlett-Stevens H., Craske M.G., Mayer E.A., et al. Prevalence of irritable bowel syndrome among university students: the roles of worry, neuroticism, anxiety sensitivity and visceral anxiety. J Psychosom Res 55 (2003) 501-505
8. Apkarian A.V., Bushnell M.C., Treede R.D., et al. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 9 (2005) 463-484
9. Kwan C.L., Diamant N.E., Pope G., et al. Abnormal forebrain activity in functional bowel disorder patients with chronic pain. Neurology 65 (2005) 1268-1277
10. Tracey I. Imaging pain. Br J Anaesth 101 (2008) 32-39
11. Silverman D.H., Munakata J.A., Ennes H., et al. Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 112 (1997) 64-72
12. Apkarian A.V., Sosa Y., Sonty S., et al. Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci 24 (2004) 10410-10415
13. Schmidt-Wilcke T., Leinisch E., Straube A., et al. Gray matter decrease in patients with chronic tension type headache. Neurology 65 (2005) 1483-1486
14. Geha P.Y., Baliki M.N., Harden R.N., et al. The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regions. Neuron 60 (2008) 570-581
15. Kuchinad A., Schweinhardt P., Seminowicz D.A., et al. Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?. J Neurosci 27 (2007) 4004-4007
16. Davis K.D., Pope G., Chen J., et al. Cortical thinning in IBS: implications for homeostatic, attention, and pain processing. Neurology 70 (2008) 153-154
17. May A. Chronic pain may change the structure of the brain. Pain 137 (2008) 7-15
18. Taylor K.S., Anastakis D.J., and Davis K.D. Cutting your nerve changes your brain. Brain 132 (2009) 3122-3133
19. Millan M.J. Descending control of pain. Prog Neurobiol 66 (2002) 355-474
20. Wiech K., Ploner M., and Tracey I. Neurocognitive aspects of pain perception. Trends Cogn Sci 12 (2008) 306-313
21. Wamsley J.K., Zarbin M.A., Young III W.S., et al. Distribution of opiate receptors in the monkey brain: an autoradiographic study. Neuroscience 7 (1982) 595-613
22. Pfeiffer A., Pasi A., Mehraein P., et al. Opiate receptor binding sites in human brain. Brain Res 248 (1982) 87-96
23. Lackner J.M., Quigley B.M., and Blanchard E.B. Depression and abdominal pain in IBS patients: the mediating role of catastrophizing. Psychosom Med 66 (2004) 435-441
24. Sullivan M.J., Bishop S.R., and Pivik J. The pain catastrophizing scale: development and validation. Psychol Assess 7 (1995) 524-532
25. Severeijns R., Vlaeyen J.W., van den Hout M.A., et al. Pain catastrophizing predicts pain intensity, disability, and psychological distress independent of the level of physical impairment. Clin J Pain 17 (2001) 165-172
26. Fukudo S. Role of corticotropin-releasing hormone in irritable bowel syndrome and intestinal inflammation. J Gastroenterol 42 Suppl 17 (2007) 48-51
27. Heitkemper M., Jarrett M., Cain K., et al. Increased urine catecholamines and cortisol in women with irritable bowel syndrome. Am J Gastroenterol 91 (1996) 906-913
28. Walter S.A., Ardal-Eriksson E., Thorell L.H., et al. Pre-experimental stress in patients with irritable bowel syndrome: high cortisol values already before symptom provocation with rectal distensions. Neurogastroenterol Motil 18 (2006) 1069-1077
29. Coutinho S.V., Plotsky P.M., Sablad M., et al. Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat. Am J Physiol Gastrointest Liver Physiol 282 (2002) G307-G316
30. Soderholm J.D., Yates D.A., Gareau M.G., et al. Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress. Am J Physiol Gastrointest Liver Physiol 283 (2002) G1257-G1263
31. O'Mahony S.M., Marchesi J.R., Scully P., et al. Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol Psychiatry 65 (2008) 263-267
32. Jones M.P., Dilley J.B., Drossman D., et al. Brain-gut connections in functional GI disorders: anatomic and physiologic relationships. Neurogastroenterol Motil 18 (2006) 91-103
33. Taylor K.S., Seminowicz D.A., and Davis K.D. Two systems of resting state connectivity between the insula and cingulate cortex. Hum Brain Mapp 30 (2008) 2731-2745
34. Craig A.D. How do you feel-now?. The anterior insula and human awareness. Nat Rev Neurosci 10 (2009) 59-70