-
1
-
-
0033574273
-
MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia
-
Abbott, G. W., Sesti, F., Splawski, I., Buck, M. E., Lehmann, M. H., Timothy, K. W., Keating, M. T., and Goldstein, S. A. (1999). MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. Cell 97, 175-187.
-
(1999)
Cell
, vol.97
, pp. 175-187
-
-
Abbott, G.W.1
Sesti, F.2
Splawski, I.3
Buck, M.E.4
Lehmann, M.H.5
Timothy, K.W.6
Keating, M.T.7
Goldstein, S.A.8
-
2
-
-
0036789419
-
KCNE5 induces timeand voltage-dependent modulation of the KCNQ1 current
-
Angelo, K., Jespersen, T., Grunnet, M., Nielsen, M. S., Klaerke, D. A., and Olesen, S.-P. (2002). KCNE5 induces timeand voltage-dependent modulation of the KCNQ1 current. Biophys. J. 83, 1997-2006.
-
(2002)
Biophys. J.
, vol.83
, pp. 1997-2006
-
-
Angelo, K.1
Jespersen, T.2
Grunnet, M.3
Nielsen, M.S.4
Klaerke, D.A.5
Olesen, S.-P.6
-
3
-
-
25444519458
-
2+ sensitivity is enhanced by its beta1 subunit
-
2+ sensitivity is enhanced by its beta1 subunit. J. Gen. Physiol. 126, 393-412.
-
(2005)
J. Gen. Physiol.
, vol.126
, pp. 393-412
-
-
Bao, L.1
Cox, D.H.2
-
4
-
-
0029952101
-
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
-
Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., and Romey, G. (1996). K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384, 78-80.
-
(1996)
Nature
, vol.384
, pp. 78-80
-
-
Barhanin, J.1
Lesage, F.2
Guillemare, E.3
Fink, M.4
Lazdunski, M.5
Romey, G.6
-
5
-
-
0034717111
-
hKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calciumactivated potassium channel beta subunit family
-
Behrens, R., Nolting, A., Reimann, F., Schwarz, M., Waldschutz, R., and Pongs, O. (2000). hKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calciumactivated potassium channel beta subunit family. FEBS Lett. 474, 99-106.
-
(2000)
FEBS Lett.
, vol.474
, pp. 99-106
-
-
Behrens, R.1
Nolting, A.2
Reimann, F.3
Schwarz, M.4
Waldschutz, R.5
Pongs, O.6
-
6
-
-
2542491002
-
Mutation in the KCNQ1 gene leading to the short QT-interval syndrome
-
Bellocq, C., Van Ginneken, A. C. G., Bezzina, C. R., Alders, M., Escande, D., Mannens, M. M. A. M., Baro, I., and Wilde, A. A. M. (2004). Mutation in the KCNQ1 gene leading to the short QT-interval syndrome. Circulation 109, 2394-2397.
-
(2004)
Circulation
, vol.109
, pp. 2394-2397
-
-
Bellocq, C.1
Van Ginneken, A.C.G.2
Bezzina, C.R.3
Alders, M.4
Escande, D.5
Mannens, M.M.A.M.6
Baro, I.7
Wilde, A.A.M.8
-
8
-
-
41149095488
-
How membrane proteins sense voltage
-
Bezanilla, F. (2008). How membrane proteins sense voltage. Nat. Rev. Mol. Cell Biol. 9, 323-332.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 323-332
-
-
Bezanilla, F.1
-
9
-
-
36649017644
-
Role of the S6 C-terminus in KCNQ1 channel gating
-
Boulet, I. R., Labro, A. J., Raes, A. L., and Snyders, D. J. (2007). Role of the S6 C-terminus in KCNQ1 channel gating. J. Physiol. 585, 325-337.
-
(2007)
J. Physiol.
, vol.585
, pp. 325-337
-
-
Boulet, I.R.1
Labro, A.J.2
Raes, A.L.3
Snyders, D.J.4
-
10
-
-
0026575435
-
Regulation of arterial tone by activation of calcium-dependent potassium channels
-
Brayden, J. E., and Nelson, M. T. (1992). Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256, 532-535.
-
(1992)
Science
, vol.256
, pp. 532-535
-
-
Brayden, J.E.1
Nelson, M.T.2
-
11
-
-
0034009387
-
Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4
-
Brenner, R., Jegla, T. J., Wickenden, A., Liu, Y., and Aldrich, R. W. (2000). Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4. J. Biol. Chem. 275, 6453-6461.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6453-6461
-
-
Brenner, R.1
Jegla, T.J.2
Wickenden, A.3
Liu, Y.4
Aldrich, R.W.5
-
12
-
-
0030610509
-
The role of the IsK protein in the specific pharmacological properties of the IKs channel complex
-
Busch, A. E., Busch, G. L., Ford, E., Suessbrich, H., Lang, H. J., Greger, R., Kunzelmann, K., Attali, B., and Stühmer, W. (1997). The role of the IsK protein in the specific pharmacological properties of the IKs channel complex. Br. J. Pharmacol. 122, 187-189.
-
(1997)
Br. J. Pharmacol.
, vol.122
, pp. 187-189
-
-
Busch, A.E.1
Busch, G.L.2
Ford, E.3
Suessbrich, H.4
Lang, H.J.5
Greger, R.6
Kunzelmann, K.7
Attali, B.8
Stühmer, W.9
-
13
-
-
84858110206
-
Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1
-
Chan, P. J., Osteen, J. D., Xiong, D., Bohnen, M. S., Doshi, D., Sampson, K. J., Marx, S. O., Karlin, A., and Kass, R. S. (2012). Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1. J. Gen. Physiol. 139, 135-144.
-
(2012)
J. Gen. Physiol.
, vol.139
, pp. 135-144
-
-
Chan, P.J.1
Osteen, J.D.2
Xiong, D.3
Bohnen, M.S.4
Doshi, D.5
Sampson, K.J.6
Marx, S.O.7
Karlin, A.8
Kass, R.S.9
-
14
-
-
64549110297
-
Functional interactions between KCNE1 C-terminus and the KCNQ1 channel
-
doi:10.1371/journal.pone.000514
-
Chen, J., Zheng, R., Melman, Y. F., and McDonald, T. V. (2009). Functional interactions between KCNE1 C-terminus and the KCNQ1 channel. PLoS ONE 4, e5143. doi:10.1371/journal.pone.0005143
-
(2009)
PLoS ONE
, vol.4
-
-
Chen, J.1
Zheng, R.2
Melman, Y.F.3
McDonald, T.V.4
-
15
-
-
47749111365
-
Lysine-rich extracellular rings formed by hβ2 subunits confer the outward rectification of BK channels
-
doi:10.1371/journal.pone.000211
-
Chen, M., Gan, G., Wu,Y., Wang, L., and Ding, J. (2008). Lysine-rich extracellular rings formed by hβ2 subunits confer the outward rectification of BK channels. PLoS ONE 3, e2114. doi:10.1371/journal.pone.0002114
-
(2008)
PLoS ONE
, vol.3
-
-
Chen, M.1
Gan, G.2
Wu, Y.3
Wang, L.4
Ding, J.5
-
16
-
-
0037428218
-
KCNQ1 gain-of-function mutation in familial atrial fibrillation
-
Chen, Y.-H., Xu, S.-J., Bendahhou, S., Wang, X.-L., Wang, Y., Xu, W.Y., Jin, H.-W., Sun, H., Su, X.-Y., Zhuang, Q.-N., Yang, Y.-Q., Li, Y.B., Liu, Y., Xu, H.-J., Li, X.-F., Ma, N., Mou, C.-P., Chen, Z., Barhanin, J., and Huang, W. (2003). KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science 299, 251-254.
-
(2003)
Science
, vol.299
, pp. 251-254
-
-
Chen, Y.-H.1
Xu, S.-J.2
Bendahhou, S.3
Wang, X.-L.4
Wang, Y.5
Xu, W.Y.6
Jin, H.-W.7
Sun, H.8
Su, X.-Y.9
Zhuang, Q.-N.10
Yang, Y.-Q.11
Li, Y.B.12
Liu, Y.13
Xu, H.-J.14
Li, X.-F.15
Ma, N.16
Mou, C.-P.17
Chen, Z.18
Barhanin, J.19
Huang, W.20
more..
-
17
-
-
58849133458
-
Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide crosslinking of substituted cysteines
-
Chung, D. Y., Chan, P. J., Bankston, J. R., Yang, L., Liu, G., Marx, S. O., Karlin, A., and Kass, R. S. (2009). Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide crosslinking of substituted cysteines. Proc. Natl. Acad. Sci. U.S.A. 106, 743-748.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 743-748
-
-
Chung, D.Y.1
Chan, P.J.2
Bankston, J.R.3
Yang, L.4
Liu, G.5
Marx, S.O.6
Karlin, A.7
Kass, R.S.8
-
18
-
-
0033624549
-
Role of the beta1 subunit in large-conductance Ca(2+)- activatedK(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity
-
Cox, D. H., and Aldrich, R. W. (2000). Role of the beta1 subunit in large-conductance Ca(2+)- activatedK(+) channel gating energetics. Mechanisms of enhanced Ca(2+) sensitivity. J. Gen. Physiol. 116, 411-432.
-
(2000)
J. Gen. Physiol.
, vol.116
, pp. 411-432
-
-
Cox, D.H.1
Aldrich, R.W.2
-
19
-
-
67650738504
-
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation
-
Das, S., Makino, S., Melman, Y. F., Shea, M. A., Goyal, S. B., Rosenzweig, A., Macrae, C. A., and Ellinor, P. T. (2009). Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart rhythm 6, 1146-1153.
-
(2009)
Heart rhythm
, vol.6
, pp. 1146-1153
-
-
Das, S.1
Makino, S.2
Melman, Y.F.3
Shea, M.A.4
Goyal, S.B.5
Rosenzweig, A.6
Macrae, C.A.7
Ellinor, P.T.8
-
20
-
-
39049099153
-
The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns
-
doi:10.1186/1471-2164-10-230
-
Dolan, J., Walshe, K., Alsbury, S., Hokamp, K., O'Keeffe, S., Okafuji, T., Miller, S. F. C., Tear, G., and Mitchell, K. J. (2007). The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genomics 8, 320. doi:10.1186/1471-2164-10-230
-
(2007)
BMC Genomics
, vol.8
, pp. 320
-
-
Dolan, J.1
Walshe, K.2
Alsbury, S.3
Hokamp, K.4
O'Keeffe, S.5
Okafuji, T.6
Miller, S.F.C.7
Tear, G.8
Mitchell, K.J.9
-
21
-
-
0033597857
-
Long QT syndromeassociated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits
-
Franqueza,L.,Lin,M.,Shen,J.,Splawski, I., Keating, M. T., and Sanguinetti, M. C. (1999). Long QT syndromeassociated mutations in the S4-S5 linker of KvLQT1 potassium channels modify gating and interaction with minK subunits. J. Biol. Chem. 274, 21063-21070.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21063-21070
-
-
Franqueza, L.1
Lin, M.2
Shen, J.3
Splawski, I.4
Keating, M.T.5
Sanguinetti, M.C.6
-
22
-
-
10344225088
-
KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels
-
Gage, S. D., and Kobertz, W. R. (2004). KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels. J. Gen. Physiol. 124, 759-771.
-
(2004)
J. Gen. Physiol.
, vol.124
, pp. 759-771
-
-
Gage, S.D.1
Kobertz, W.R.2
-
23
-
-
0026059250
-
Site-specific mutations in a minimal voltage-dependent K+ channel alter ion selectivity and open-channel block
-
Goldstein, S. A., and Miller, C. (1991). Site-specific mutations in a minimal voltage-dependent K+ channel alter ion selectivity and open-channel block. Neuron 7, 403-408.
-
(1991)
Neuron
, vol.7
, pp. 403-408
-
-
Goldstein, S.A.1
Miller, C.2
-
24
-
-
33846694346
-
Structure prediction for the down state of a potassium channel voltage sensor
-
Grabe, M., Lai, H. C., Jain, M., Jan,Y. N., and Jan, L. Y. (2007). Structure prediction for the down state of a potassium channel voltage sensor. Nature 445, 550-553.
-
(2007)
Nature
, vol.445
, pp. 550-553
-
-
Grabe, M.1
Lai, H.C.2
Jain, M.3
Jan, Y.N.4
Jan, L.Y.5
-
25
-
-
0036660596
-
KCNE4 is an inhibitory subunit to the KCNQ1 channel
-
Grunnet, M., Jespersen, T., Rasmussen, H. B., Ljungstrøm, T., Jorgensen, N. K., Olesen, S.-P., and Klaerke, D. A. (2002). KCNE4 is an inhibitory subunit to the KCNQ1 channel. J. Physiol. 542, 119-130.
-
(2002)
J. Physiol.
, vol.542
, pp. 119-130
-
-
Grunnet, M.1
Jespersen, T.2
Rasmussen, H.B.3
Ljungstrøm, T.4
Jorgensen, N.K.5
Olesen, S.-P.6
Klaerke, D.A.7
-
26
-
-
84862970522
-
An extracellular domain of the accessory beta1 subunit is required for modulating BK channel voltage sensor and gate
-
Gruslova, A., Semenov, I., and Wang, B. (2012). An extracellular domain of the accessory beta1 subunit is required for modulating BK channel voltage sensor and gate. J. Gen. Physiol. 139, 57-67.
-
(2012)
J. Gen. Physiol.
, vol.139
, pp. 57-67
-
-
Gruslova, A.1
Semenov, I.2
Wang, B.3
-
27
-
-
79956125732
-
Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain
-
Haddad, G. A., and Blunck, R. (2011). Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain. J. Gen. Physiol. 137, 455-472.
-
(2011)
J. Gen. Physiol.
, vol.137
, pp. 455-472
-
-
Haddad, G.A.1
Blunck, R.2
-
28
-
-
67651151053
-
Intracellular domains interactions and gated motions of I(KS) potassium channel subunits
-
Haitin, Y., Wiener, R., Shaham, D., Peretz, A., Cohen, E. B.-T., Shamgar, L., Pongs, O., Hirsch, J. A., and Attali, B. (2009). Intracellular domains interactions and gated motions of I(KS) potassium channel subunits. EMBO J. 28, 1994-2005.
-
(2009)
EMBO J.
, vol.28
, pp. 1994-2005
-
-
Haitin, Y.1
Wiener, R.2
Shaham, D.3
Peretz, A.4
Cohen, E.B.-T.5
Shamgar, L.6
Pongs, O.7
Hirsch, J.A.8
Attali, B.9
-
29
-
-
0032569024
-
The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding
-
Hanner, M., Vianna-Jorge, R., Kamassah, A., Schmalhofer, W. A., Knaus, H. G.,Kaczorowski,G. J.,and Garcia, M. L. (1998). The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding. J. Biol. Chem. 273, 16289-16296.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16289-16296
-
-
Hanner, M.1
Vianna-Jorge, R.2
Kamassah, A.A.3
Knaus, H.G.4
Kaczorowski, G.J.5
Garcia, M.L.6
-
30
-
-
70449435450
-
The genetic basis of long QT and short QT syndromes: a mutation update
-
Hedley,P. L.,Jørgensen,P.,Schlamowitz, S.,Wangari, R., Moolman-Smook, J., Brink,P.A.,Kanters,J. K.,Corfield,V. A., and Christiansen, M. (2009). The genetic basis of long QT and short QT syndromes: a mutation update. Hum. Mutat. 30, 1486-1511.
-
(2009)
Hum. Mutat.
, vol.30
, pp. 1486-1511
-
-
Hedley, P.L.1
Jørgensen, P.2
Schlamowitz, S.3
Wangari, R.4
Moolman-Smook, J.5
Brink, P.A.6
Kanters, J.K.7
Corfield, V.A.8
Christiansen, M.9
-
31
-
-
27644587864
-
De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero
-
Hong, K., Piper, D. R., Diaz-Valdecantos, A., Brugada, J., Oliva, A., Burashnikov, E., Santos- De-Soto, J., Grueso-Montero, J., Diaz-Enfante, E., Brugada, P., Sachse, F., Sanguinetti, M. C., and Brugada, R. (2005). De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero. Cardiovasc. Res. 68, 433-440.
-
(2005)
Cardiovasc. Res.
, vol.68
, pp. 433-440
-
-
Hong, K.1
Piper, D.R.A.2
Brugada, J.3
Oliva, A.4
Burashnikov, E.5
Santos-De-Soto, J.6
Grueso-Montero, J.7
Diaz-Enfante, E.8
Brugada, P.9
Sachse, F.10
Sanguinetti, M.C.11
Brugada, R.12
-
32
-
-
0036714915
-
2+ binding and channel opening in large conductance (BK) potassium channels
-
2+ binding and channel opening in large conductance (BK) potassium channels. J. Gen. Physiol. 120, 267-305.
-
(2002)
J. Gen. Physiol.
, vol.120
, pp. 267-305
-
-
Horrigan, F.T.1
Aldrich, R.W.2
-
33
-
-
0032811552
-
Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+)
-
Horrigan, F. T., Cui, J., and Aldrich, R. W. (1999). Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+). J. Gen. Physiol. 114, 277-304.
-
(1999)
J. Gen. Physiol.
, vol.114
, pp. 277-304
-
-
Horrigan, F.T.1
Cui, J.2
Aldrich, R.W.3
-
34
-
-
33846613319
-
Slow delayed rectifier potassium current (IKs) and the repolarization reserve
-
Jost, N., Papp, J. G., and Varró, A. (2007). Slow delayed rectifier potassium current (IKs) and the repolarization reserve. Ann. Noninvasive Electrocardiol. 12, 64-78.
-
(2007)
Ann. Noninvasive Electrocardiol.
, vol.12
, pp. 64-78
-
-
Jost, N.1
Papp, J.G.2
Varró, A.3
-
35
-
-
48649098982
-
Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel
-
Kang, C., Tian, C., Sönnichsen, F. D., Smith, J. A., Meiler, J., George, A. L., Vanoye, C. G., Kim, H. J., and Sanders, C. R. (2008). Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel. Biochemistry 47, 7999-8006.
-
(2008)
Biochemistry
, vol.47
, pp. 7999-8006
-
-
Kang, C.1
Tian, C.2
Sönnichsen, F.D.3
Smith, J.A.4
Meiler, J.5
George, A.L.6
Vanoye, C.G.7
Kim, H.J.8
Sanders, C.R.9
-
36
-
-
0028318835
-
+ channel from smooth muscle
-
+ channel from smooth muscle. J. Biol. Chem. 269, 17274-17278.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17274-17278
-
-
Knaus, H.G.1
Folander, K.2
Garcia Calvo, M.3
Garcia, M.L.4
Kaczorowski, G.J.5
Smith, M.6
Swanson, R.7
-
37
-
-
33847340188
-
A role for the S0 transmembrane segment in voltage-dependent gating of BK channels
-
Koval, O. M., Fan,Y., and Rothberg, B. S. (2007). A role for the S0 transmembrane segment in voltage-dependent gating of BK channels. J. Gen. Physiol. 129, 209-220.
-
(2007)
J. Gen. Physiol.
, vol.129
, pp. 209-220
-
-
Koval, O.M.1
Fan, Y.2
Rothberg, B.S.3
-
38
-
-
0037451123
-
AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucinerich repeats
-
Kuja-Panula, J. (2003). AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucinerich repeats. J. Cell Biol. 160, 963-973.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 963-973
-
-
Kuja-Panula, J.1
-
39
-
-
66149104516
-
KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel
-
Kurokawa, J., Bankston, J. R., Kaihara, A., Chen, L., Furukawa, T., and Kass, R. S. (2009). KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. Channels (Austin) 3, 16-24.
-
(2009)
Channels (Austin)
, vol.3
, pp. 16-24
-
-
Kurokawa, J.1
Bankston, J.R.2
Kaihara, A.3
Chen, L.4
Furukawa, T.5
Kass, R.S.6
-
40
-
-
0037452722
-
Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel
-
Kurokawa, J., Chen, L., and Kass, R. S. (2003). Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel. Proc. Natl. Acad. Sci. U.S.A. 100, 2122-2127.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 2122-2127
-
-
Kurokawa, J.1
Chen, L.2
Kass, R.S.3
-
41
-
-
78650959213
-
The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure
-
Labro, A. J., Boulet, I. R., Choveau, F. S., Mayeur, E., Bruyns, T., Loussouarn, G., Raes, A. L., and Snyders, D. J. (2011). The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure. J. Biol. Chem. 286, 717-725.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 717-725
-
-
Labro, A.J.1
Boulet, I.R.2
Choveau, F.S.3
Mayeur, E.4
Bruyns, T.5
Loussouarn, G.6
Raes, A.L.7
Snyders, D.J.8
-
42
-
-
0023159115
-
Properties of two calciumactivated hyperpolarizations in rat hippocampal neurones
-
Lancaster, B., and Nicoll, R. A. (1987). Properties of two calciumactivated hyperpolarizations in rat hippocampal neurones. J. Physiol. 389, 187-203.
-
(1987)
J. Physiol.
, vol.389
, pp. 187-203
-
-
Lancaster, B.1
Nicoll, R.A.2
-
43
-
-
0032894433
-
Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation
-
Ledwell, J. L., and Aldrich, R. W. (1999). Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J. Gen. Physiol. 113, 389-414.
-
(1999)
J. Gen. Physiol.
, vol.113
, pp. 389-414
-
-
Ledwell, J.L.1
Aldrich, R.W.2
-
45
-
-
63849267426
-
{beta} subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia
-
Lee, U. S., and Cui, J. (2009). {beta} subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia. J. Physiol. 587, 1481-1498.
-
(2009)
J. Physiol.
, vol.587
, pp. 1481-1498
-
-
Lee, U.S.1
Cui, J.2
-
46
-
-
78649728181
-
Modulation of BK channel gating by the ss2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1
-
Lee, U. S., Shi, J., and Cui, J. (2010). Modulation of BK channel gating by the ss2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1. J. Neurosci. 30, 16170-16179.
-
(2010)
J. Neurosci.
, vol.30
, pp. 16170-16179
-
-
Lee, U.S.1
Shi, J.2
Cui, J.3
-
47
-
-
0034537358
-
Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols
-
Lerche, C., Seebohm, G., Wagner, C. I., Scherer, C. R., Dehmelt, L., Abitbol, I., Gerlach, U., Brendel, J., Attali, B., and Busch, A. E. (2000). Molecular impact of MinK on the enantiospecific block of I(Ks) by chromanols. Br. J. Pharmacol. 131, 1503-1506.
-
(2000)
Br. J. Pharmacol.
, vol.131
, pp. 1503-1506
-
-
Lerche, C.1
Seebohm, G.2
Wagner, C.I.3
Scherer, C.R.4
Dehmelt, L.5
Abitbol, I.6
Gerlach, U.7
Brendel, J.8
Attali, B.9
Busch, A.E.10
-
48
-
-
34547100546
-
Interaction sites between the Slo1 pore and the NH2 terminus of the beta2 subunit, probed with a three-residue sensor
-
Li, H., Yao, J., Tong, X., Guo, Z., Wu, Y., Sun, L., Pan, N., Wu, H., Xu, T., and Ding, J. (2007). Interaction sites between the Slo1 pore and the NH2 terminus of the beta2 subunit, probed with a three-residue sensor. J. Biol. Chem. 282, 17720-17728.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17720-17728
-
-
Li, H.1
Yao, J.2
Tong, X.3
Guo, Z.4
Wu, Y.5
Sun, L.6
Pan, N.7
Wu, H.8
Xu, T.9
Ding, J.10
-
49
-
-
79959352977
-
KCNE1 enhances phosphatidylinositol 4,5- bisphosphate (PIP2) sensitivity of IKs to modulate channel activity
-
Li, Y., Zaydman, M. A., Wu, D., Shi, J., Guan, M., Virgin-Downey, B., and Cui, J. (2011). KCNE1 enhances phosphatidylinositol 4,5- bisphosphate (PIP2) sensitivity of IKs to modulate channel activity. Proc. Natl. Acad. Sci. U.S.A. 108, 9095-9100.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 9095-9100
-
-
Li, Y.1
Zaydman, M.A.2
Wu, D.3
Shi, J.4
Guan, M.5
Virgin-Downey, B.6
Cui, J.7
-
50
-
-
77951728181
-
Location of modulatory beta subunits in BK potassium channels
-
Liu, G., Niu, X., Wu, R. S., Chudasama, N., Yao, Y., Jin, X., Weinberg, R., Zakharov, S. I., Motoike, H., Marx, S. O., and Karlin, A. (2010). Location of modulatory beta subunits in BK potassium channels. J. Gen. Physiol. 135, 449-459.
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 449-459
-
-
Liu, G.1
Niu, X.2
Wu, R.S.3
Chudasama, N.4
Jin, X.5
Weinberg, R.6
Zakharov, S.I.7
Motoike, H.8
Marx, S.O.9
Karlin, A.10
-
51
-
-
44349137529
-
Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking
-
Liu, G., Zakharov, S. I., Yang, L., Deng, S. X., Landry, D. W., Karlin, A., and Marx, S. O. (2008a). Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking. J. Gen. Physiol. 131, 537-548.
-
(2008)
J. Gen. Physiol.
, vol.131
, pp. 537-548
-
-
Liu, G.1
Zakharov, S.I.2
Yang, L.3
Deng, S.X.4
Landry, D.W.5
Karlin, A.6
Marx, S.O.7
-
52
-
-
49449117056
-
Locations of the 1 transmembrane helices in the BK potassium channel
-
Liu, G., Zakharov, S. I., Yang, L., Wu, R. S., Deng, S. X., Landry, D. W., Karlin, A., and Marx, S. O. (2008b). Locations of the 1 transmembrane helices in the BK potassium channel. Proc. Natl. Acad. Sci. U.S.A. 105, 10727-10732.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 10727-10732
-
-
Liu, G.1
Zakharov, S.I.2
Yang, L.3
Wu, R.S.4
Deng, S.X.5
Landry, D.W.6
Karlin, A.7
Marx, S.O.8
-
53
-
-
23244441222
-
Voltage sensor of Kv1.2: structural basis of electromechanical coupling
-
Long, S. B., Campbell, E. B., and Mackinnon, R. (2005). Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 309, 903-908.
-
(2005)
Science
, vol.309
, pp. 903-908
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
54
-
-
0035950089
-
Ion conduction pore is conserved among potassium channels
-
Lu,Z.,Klem,A. M.,and Ramu,Y. (2001). Ion conduction pore is conserved among potassium channels. Nature 413, 809-813.
-
(2001)
Nature
, vol.413
, pp. 809-813
-
-
Lu, Z.1
Klem, A.M.2
Ramu, Y.3
-
55
-
-
36549055058
-
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval
-
Lundby, A., Ravn, L. S., Svendsen, J. H., Olesen,S.-P.,and Schmitt,N. (2007). KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval. Heart rhythm 4, 1532-1541.
-
(2007)
Heart rhythm
, vol.4
, pp. 1532-1541
-
-
Lundby, A.1
Ravn, L.S.2
Svendsen, J.H.3
Olesen, S.-P.4
Schmitt, N.5
-
56
-
-
77953041426
-
Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1
-
Lvov, A., Gage, S. D., Berrios, V. M., and Kobertz, W. R. (2010). Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1. J. Gen. Physiol. 135, 607-618.
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 607-618
-
-
Lvov, A.1
Gage, S.D.2
Berrios, V.M.3
Kobertz, W.R.4
-
57
-
-
33644610046
-
Role of charged residues in the S1-S4 voltage sensor of BK channels
-
Ma, Z., Lou, X. J., and Horrigan, F. T. (2006). Role of charged residues in the S1-S4 voltage sensor of BK channels. J. Gen. Physiol. 127, 309-328.
-
(2006)
J. Gen. Physiol.
, vol.127
, pp. 309-328
-
-
Ma, Z.1
Lou, X.J.2
Horrigan, F.T.3
-
58
-
-
0019827872
-
Ca-dependent K channels with large unitary conductance in chromaffin cell membranes
-
Marty,A. (1981). Ca-dependent K channels with large unitary conductance in chromaffin cell membranes. Nature 291, 497-500.
-
(1981)
Nature
, vol.291
, pp. 497-500
-
-
Marty, A.1
-
59
-
-
0037127028
-
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1- KCNE1 potassium channel
-
Marx, S. O., Kurokawa, J., Reiken, S., Motoike, H., D'Armiento, J., Marks, A. R.,and Kass,R. S. (2002). Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1- KCNE1 potassium channel. Science 295, 496-499.
-
(2002)
Science
, vol.295
, pp. 496-499
-
-
Marx, S.O.1
Kurokawa, J.2
Reiken, S.3
Motoike, H.4
D'Armiento, J.5
Marks, A.R.6
Kass, R.S.7
-
60
-
-
0028926916
-
Functional role of the beta subunit of high conductance calcium-activated potassium channels
-
McManus, O. B., Helms, L. M., Pallanck, L., Ganetzky, B., Swanson, R., and Leonard,R. J. (1995). Functional role of the beta subunit of high conductance calcium-activated potassium channels. Neuron 14, 645-650.
-
(1995)
Neuron
, vol.14
, pp. 645-650
-
-
McManus, O.B.1
Helms, L.M.2
Pallanck, L.3
Ganetzky, B.4
Swanson, R.5
Leonard, R.J.6
-
61
-
-
0034625068
-
+ channel resistant to charybdotoxin and iberiotoxin
-
+ channel resistant to charybdotoxin and iberiotoxin. Proc. Natl. Acad. Sci. U.S.A. 97, 5562-5567.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 5562-5567
-
-
Meera, P.1
-
62
-
-
0035794229
-
Structural determinants of KvLQT1 control by the KCNE family of proteins
-
Melman, Y. F., Domènech, A., De La Luna, S., and McDonald, T. V. (2001). Structural determinants of KvLQT1 control by the KCNE family of proteins. J. Biol. Chem. 276, 6439-6444.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6439-6444
-
-
Melman, Y.F.1
Domènech, A.2
De La Luna, S.3
McDonald, T.V.4
-
63
-
-
0037067686
-
A single transmembrane site in the KCNE- encoded proteins controls the specificity of KvLQT1 channel gating
-
Melman, Y. F., Krumerman, A., and McDonald, T. V. (2002). A single transmembrane site in the KCNE- encoded proteins controls the specificity of KvLQT1 channel gating. J. Biol. Chem. 277, 25187-25194.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25187-25194
-
-
Melman, Y.F.1
Krumerman, A.2
McDonald, T.V.3
-
64
-
-
2942746320
-
KCNE1 binds to the KCNQ1 pore to regulate potassium channel activity
-
Melman, Y. F., Um, S. Y., Krumerman, A., Kagan, A., and McDonald, T. V. (2004). KCNE1 binds to the KCNQ1 pore to regulate potassium channel activity. Neuron 42, 927-937.
-
(2004)
Neuron
, vol.42
, pp. 927-937
-
-
Melman, Y.F.1
Um, S.Y.2
Krumerman, A.3
Kagan, A.4
McDonald, T.V.5
-
65
-
-
33645519955
-
Defining the BK channel domains required for beta1-subunit modulation
-
Morrow, J. P., Zakharov, S. I., Liu, G., Yang, L., Sok, A. J., and Marx, S. O. (2006). Defining the BK channel domains required for beta1-subunit modulation. Proc. Natl. Acad. Sci. U.S.A. 103, 5096-5101.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 5096-5101
-
-
Morrow, J.P.1
Zakharov, S.I.2
Liu, G.3
Yang, L.4
Sok, A.J.5
Marx, S.O.6
-
66
-
-
34548825159
-
KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel
-
Nakajo, K., and Kubo, Y. (2007). KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel. J. Gen. Physiol. 130, 269-281.
-
(2007)
J. Gen. Physiol.
, vol.130
, pp. 269-281
-
-
Nakajo, K.1
Kubo, Y.2
-
67
-
-
80555144260
-
KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue
-
Nakajo, K., Nishino, A., Okamura, Y., and Kubo, Y. (2011). KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue. J. Gen. Physiol. 138, 521-535.
-
(2011)
J. Gen. Physiol.
, vol.138
, pp. 521-535
-
-
Nakajo, K.1
Nishino, A.2
Okamura, Y.3
Kubo, Y.4
-
69
-
-
0034046234
-
2+-independent mechanism
-
2+-independent mechanism. J. Gen. Physiol. 115, 719-736.
-
(2000)
J. Gen. Physiol.
, vol.115
, pp. 719-736
-
-
Nimigean, C.M.1
-
70
-
-
0032948417
-
+-activated potassium channels by retaining the gating in the bursting states
-
2+-activated potassium channels by retaining the gating in the bursting states. J. Gen. Physiol. 113, 425-440.
-
(1999)
J. Gen. Physiol.
, vol.113
, pp. 425-440
-
-
Nimigean, C.M.1
Magleby, K.L.2
-
71
-
-
17044420817
-
Differential effects of beta 1 and beta 2 subunits on BK channel activity
-
Orio, P., and Latorre, R. (2005). Differential effects of beta 1 and beta 2 subunits on BK channel activity. J. Gen. Physiol. 125, 395-411.
-
(2005)
J. Gen. Physiol.
, vol.125
, pp. 395-411
-
-
Orio, P.1
Latorre, R.2
-
72
-
-
0036667281
-
New disguises for an old channel: MaxiK channel beta-subunits
-
Orio, P., Rojas, P., Ferreira, G., and Latorre, R. (2002). New disguises for an old channel: MaxiK channel beta-subunits. News Physiol. Sci. 17, 156-161.
-
(2002)
News Physiol. Sci.
, vol.17
, pp. 156-161
-
-
Orio, P.1
Rojas, P.2
Ferreira, G.3
Latorre, R.4
-
73
-
-
31744439840
-
+ (BK) channel
-
+ (BK) channel. J. Gen. Physiol. 127, 191-204.
-
(2006)
J. Gen. Physiol.
, vol.127
, pp. 191-204
-
-
Orio, P.1
Torres, Y.2
Rojas, P.3
Carvacho, I.4
Garcia, M.L.5
Toro, L.6
Valverde, M.A.7
Latorre, R.8
-
74
-
-
78651087721
-
KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate
-
Osteen, J. D., Gonzalez, C., Sampson, K. J., Iyer, V., Rebolledo, S., Larsson, H. P., and Kass, R. S. (2010). KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate. Proc. Natl. Acad. Sci. U.S.A. 107, 22710-22715.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 22710-22715
-
-
Osteen, J.D.1
Gonzalez, C.2
Sampson, K.J.3
Iyer, V.4
Rebolledo, S.5
Larsson, H.P.6
Kass, R.S.7
-
75
-
-
82555168278
-
AMIGO is an auxiliary subunit of the Kv2.1 potassium channel
-
Peltola, M. A., Kuja-Panula, J., Lauri, S. E., Taira, T., and Rauvala, H. (2011). AMIGO is an auxiliary subunit of the Kv2.1 potassium channel. EMBO Rep. 12, 1293-1299.
-
(2011)
EMBO Rep.
, vol.12
, pp. 1293-1299
-
-
Peltola, M.A.1
Kuja-Panula, J.2
Lauri, S.E.3
Taira, T.4
Rauvala, H.5
-
76
-
-
0033568148
-
KCNE1-like gene is deleted in AMME contiguous gene syndrome: identification and characterization of the human and mouse homologs
-
Piccini, M., Vitelli, F., Seri, M., Galietta, L. J., Moran, O., Bulfone, A., Banfi, S., Pober, B., and Renieri, A. (1999). KCNE1-like gene is deleted in AMME contiguous gene syndrome: identification and characterization of the human and mouse homologs. Genomics 60, 251-257.
-
(1999)
Genomics
, vol.60
, pp. 251-257
-
-
Piccini, M.1
Vitelli, F.2
Seri, M.3
Galietta, L.J.4
Moran, O.5
Bulfone, A.6
Banfi, S.7
Pober, B.8
Renieri, A.9
-
78
-
-
0031848480
-
Activation and inactivation of homomeric KvLQT1 potassium channels
-
Pusch, M., Magrassi, R., Wollnik, B., and Conti, F. (1998). Activation and inactivation of homomeric KvLQT1 potassium channels. Biophys. J. 75, 785-792.
-
(1998)
Biophys. J.
, vol.75
, pp. 785-792
-
-
Pusch, M.1
Magrassi, R.2
Wollnik, B.3
Conti, F.4
-
80
-
-
0029854263
-
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
-
Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Spector, P. S., Atkinson, D. L., and Keating, M. T. (1996). Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 384, 80-83.
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Zou, A.3
Shen, J.4
Spector, P.S.5
Atkinson, D.L.6
Keating, M.T.7
-
81
-
-
0025351245
-
+ current. Differential sensitivity to block by class III antiarrhythmic agents
-
+ current. Differential sensitivity to block by class III antiarrhythmic agents. J. Gen. Physiol. 96, 195-215.
-
(1990)
J. Gen. Physiol.
, vol.96
, pp. 195-215
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
-
82
-
-
34347233126
-
Modes of operation of the BKCa channel beta2 subunit
-
Savalli, N., Kondratiev, A., De Quintana, S. B., Toro, L., and Olcese, R. (2007). Modes of operation of the BKCa channel beta2 subunit. J. Gen. Physiol. 130, 117-131.
-
(2007)
J. Gen. Physiol.
, vol.130
, pp. 117-131
-
-
Savalli, N.1
Kondratiev, A.2
De Quintana, S.B.3
Toro, L.4
Olcese, R.5
-
84
-
-
0034642569
-
A constitutively open potassium channel formed by KCNQ1 and KCNE3
-
Schroeder, B. C., Waldegger, S., Fehr, S., Bleich, M., Warth, R., Greger, R., and Jentsch, T. J. (2000). A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature 403, 196-199.
-
(2000)
Nature
, vol.403
, pp. 196-199
-
-
Schroeder, B.C.1
Waldegger, S.2
Fehr, S.3
Bleich, M.4
Warth, R.5
Greger, R.6
Jentsch, T.J.7
-
85
-
-
0032435823
-
Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome
-
Sesti, F., and Goldstein, S. A. (1998). Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome. J. Gen. Physiol. 112, 651-663.
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 651-663
-
-
Sesti, F.1
Goldstein, S.A.2
-
86
-
-
44849116726
-
+ channels
-
doi:10.1371/journal.pone.000194
-
+ channels. PLoS ONE 3, e1943. doi:10.1371/journal.pone.0001943
-
(2008)
PLoS ONE
, vol.3
-
-
Shamgar, L.1
Haitin, Y.2
Yisharel, I.3
Malka, E.4
Schottelndreier, H.5
Peretz, A.6
Paas, Y.7
Attali, B.8
-
87
-
-
24744448000
-
Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve
-
Silva, J., and Rudy, Y. (2005). Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve. Circulation 112, 1384-1391.
-
(2005)
Circulation
, vol.112
, pp. 1384-1391
-
-
Silva, J.1
Rudy, Y.2
-
88
-
-
33750975638
-
Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel
-
Soler-Llavina, G. J., Chang, T. H., and Swartz, K. J. (2006). Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel. Neuron 52, 623-634.
-
(2006)
Neuron
, vol.52
, pp. 623-634
-
-
Soler-Llavina, G.J.1
Chang, T.H.2
Swartz, K.J.3
-
89
-
-
0030723260
-
Mutations in the hminK gene cause long QT syndrome and suppress IKs function
-
Splawski, I., Tristani-Firouzi, M., Lehmann, M. H., Sanguinetti, M. C., and Keating, M. T. (1997). Mutations in the hminK gene cause long QT syndrome and suppress IKs function. Nat. Genet. 17, 338-340.
-
(1997)
Nat. Genet.
, vol.17
, pp. 338-340
-
-
Splawski, I.1
Tristani-Firouzi, M.2
Lehmann, M.H.3
Sanguinetti, M.C.4
Keating, M.T.5
-
90
-
-
0023162293
-
Action potential repolarization and a fast afterhyperpolarization in rat hippocampal pyramidal cells
-
Storm, J. F. (1987). Action potential repolarization and a fast afterhyperpolarization in rat hippocampal pyramidal cells. J. Physiol. 385, 733-759.
-
(1987)
J. Physiol.
, vol.385
, pp. 733-759
-
-
Storm, J.F.1
-
91
-
-
79959415230
-
Structural basis of slow activation gating in the cardiac I Ks channel complex
-
Strutz-Seebohm, N., Pusch, M., Wolf, S., Stoll, R., Tapken, D., Gerwert, K., Attali, B., and Seebohm, G. (2011). Structural basis of slow activation gating in the cardiac I Ks channel complex. Cell. Physiol. Biochem. 27, 443-452.
-
(2011)
Cell. Physiol. Biochem.
, vol.27
, pp. 443-452
-
-
Strutz-Seebohm, N.1
Pusch, M.2
Wolf, S.3
Stoll, R.4
Tapken, D.5
Gerwert, K.6
Attali, B.7
Seebohm, G.8
-
92
-
-
0032484982
-
The conduction pore of a cardiac potassium channel
-
Tai, K. K., and Goldstein, S. A. (1998). The conduction pore of a cardiac potassium channel. Nature 391, 605-608.
-
(1998)
Nature
, vol.391
, pp. 605-608
-
-
Tai, K.K.1
Goldstein, S.A.2
-
93
-
-
0025838752
-
Alteration of channel activities and gating by mutations of slow ISK potassium channel
-
Takumi, T., Moriyoshi, K., Aramori, I., Ishii, T., Oiki, S., Okada, Y., Ohkubo, H., and Nakanishi, S. (1991). Alteration of channel activities and gating by mutations of slow ISK potassium channel. J. Biol. Chem. 266, 22192-22198.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22192-22198
-
-
Takumi, T.1
Moriyoshi, K.2
Aramori, I.3
Ishii, T.4
Oiki, S.5
Okada, Y.6
Ohkubo, H.7
Nakanishi, S.8
-
94
-
-
0023734276
-
Cloning of a membrane protein that induces a slow voltagegated potassium current
-
Takumi, T., Ohkubo, H., and Nakanishi, S. (1988). Cloning of a membrane protein that induces a slow voltagegated potassium current. Science 242, 1042-1045.
-
(1988)
Science
, vol.242
, pp. 1042-1045
-
-
Takumi, T.1
Ohkubo, H.2
Nakanishi, S.3
-
95
-
-
0033811345
-
MinK subdomains that mediate modulation of and association with KvLQT1
-
Tapper, A. R., and George, A. L. (2000). MinK subdomains that mediate modulation of and association with KvLQT1. J. Gen. Physiol. 116, 379-390.
-
(2000)
J. Gen. Physiol.
, vol.116
, pp. 379-390
-
-
Tapper, A.R.1
George, A.L.2
-
96
-
-
0035851152
-
Location and orientation of minK within the I(Ks) potassium channel complex
-
Tapper, A. R., and George, A. L. (2001). Location and orientation of minK within the I(Ks) potassium channel complex. J. Biol. Chem. 276, 38249-38254.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38249-38254
-
-
Tapper, A.R.1
George, A.L.2
-
97
-
-
0034383396
-
KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel
-
Tinel, N., Diochot, S., Borsotto, M., Lazdunski, M., and Barhanin, J. (2000). KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel. EMBO J. 19, 6326-6330.
-
(2000)
EMBO J.
, vol.19
, pp. 6326-6330
-
-
Tinel, N.1
Diochot, S.2
Borsotto, M.3
Lazdunski, M.4
Barhanin, J.5
-
98
-
-
28744445631
-
How far will you go to sense voltage?
-
Tombola, F., Pathak, M. M., and Isacoff, E. Y. (2005). How far will you go to sense voltage? Neuron 48, 719-725.
-
(2005)
Neuron
, vol.48
, pp. 719-725
-
-
Tombola, F.1
Pathak, M.M.2
Isacoff, E.Y.3
-
99
-
-
34548321727
-
A marriage of convenience: betasubunits and voltage-dependent K+ channels
-
Torres, Y. P., Morera, F. J., Carvacho, I., and Latorre, R. (2007). A marriage of convenience: betasubunits and voltage-dependent K+ channels. J. Biol. Chem. 282, 24485-24489.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24485-24489
-
-
Torres, Y.P.1
Morera, F.J.2
Latorre, R.3
-
102
-
-
0033578667
-
Acute activation of MaxiK channels (hSlo) by estradiol binding to the beta subunit
-
Valverde, M. A., Rojas, P.,Amigo, J., Cosmelli, D., Orio, P., Bahamonde, M. I., Mann,G. E.,Vergara,C.,and Latorre, R. (1999). Acute activation of MaxiK channels (hSlo) by estradiol binding to the beta subunit. Science 285, 1929-1931.
-
(1999)
Science
, vol.285
, pp. 1929-1931
-
-
Valverde, M.A.1
Rojas, P.2
Amigo, J.3
Cosmelli, D.4
Orio, P.5
Bahamonde, M.I.6
Mann, G.E.7
Vergara, C.8
Latorre, R.9
-
103
-
-
79953117902
-
Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel
-
Van Horn, W. D., Vanoye, C. G., and Sanders, C. R. (2011). Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel. Curr. Opin. Struct. Biol. 21, 283-291.
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 283-291
-
-
Van Horn, W.D.1
Vanoye, C.G.2
Sanders, C.R.3
-
104
-
-
0030461289
-
Inner ear defects induced by null mutation of the isk gene
-
Vetter, D. E., Mann, J. R., Wangemann, P.,Liu,J.,Mclaughlin,K. J.,Lesage,F., Marcus,D. C.,Lazdunski,M.,Heinemann, S. F., and Barhanin, J. (1996). Inner ear defects induced by null mutation of the isk gene. Neuron 17, 1251-1264.
-
(1996)
Neuron
, vol.17
, pp. 1251-1264
-
-
Vetter, D.E.1
Mann, J.R.2
Wangemann, P.3
Liu, J.4
Mclaughlin, K.J.5
Lesage, F.6
Marcus, D.C.7
Lazdunski, M.8
Heinemann, S.F.9
Barhanin, J.10
-
105
-
-
0037566347
-
Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation
-
Volders, P. G. A., Stengl, M., Van Opstal, J. M., Gerlach, U., Spätjens, R. L. H. M. G., Beekman, J. D. M., Sipido, K. R., and Vos, M. A. (2003). Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation. Circulation 107, 2753-2760.
-
(2003)
Circulation
, vol.107
, pp. 2753-2760
-
-
Volders, P.G.A.1
Stengl, M.2
Van Opstal, J.M.3
Gerlach, U.4
Spätjens, R.L.H.M.G.5
Beekman, J.D.M.6
Sipido, K.R.7
Vos, M.A.8
-
108
-
-
33751545568
-
An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating
-
Wang, B., and Brenner, R. (2006). An S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gating. J. Gen. Physiol. 128, 731-744.
-
(2006)
J. Gen. Physiol.
, vol.128
, pp. 731-744
-
-
Wang, B.1
Brenner, R.2
-
109
-
-
33645324028
-
Mechanism of beta4 subunit modulation of BK channels
-
Wang, B., Rothberg, B. S., and Brenner, R. (2006). Mechanism of beta4 subunit modulation of BK channels. J. Gen. Physiol. 127, 449-465.
-
(2006)
J. Gen. Physiol.
, vol.127
, pp. 449-465
-
-
Wang, B.1
Rothberg, B.S.2
Brenner, R.3
-
110
-
-
0029939875
-
MinK residues line a potassium channel pore
-
Wang, K. W., Tai, K. K., and Goldstein, S. A. (1996a). MinK residues line a potassium channel pore. Neuron 16, 571-577.
-
(1996)
Neuron
, vol.16
, pp. 571-577
-
-
Wang, K.W.1
Tai, K.K.2
Goldstein, S.A.3
-
111
-
-
9044240040
-
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
-
Wang, Q., Curran, M. E., Splawski, I., Burn, T. C., Millholland, J. M., Vanraay, T. J., Shen, J., Timothy, K. W., Vincent, G. M., De Jager, T., Schwartz, P. J., Toubin, J. A., Moss, A. J., Atkinson, D. L., Landes, G. M., Connors, T. D., and Keating, M. T. (1996b). Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat. Genet. 12, 17-23.
-
(1996)
Nat. Genet.
, vol.12
, pp. 17-23
-
-
Wang, Q.1
Curran, M.E.2
Splawski, I.3
Burn, T.C.4
Millholland, J.M.5
Vanraay, T.J.6
Shen, J.7
Timothy, K.W.8
Vincent, G.M.9
De Jager, T.10
Schwartz, P.J.11
Toubin, J.A.12
Moss, A.J.13
Atkinson, D.L.14
Landes, G.M.15
Connors, T.D.16
Keating, M.T.17
-
112
-
-
79957480803
-
Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy
-
Wang, Y. H., Jiang, M., Xu, X. L., Hsu, K.-L., Zhang, M., and Tseng, G.-N. (2011). Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy. J. Membr. Biol. 239, 137-156.
-
(2011)
J. Membr. Biol.
, vol.239
, pp. 137-156
-
-
Wang, Y.H.1
Jiang, M.2
Xu, X.L.3
Hsu, K.-L.4
Zhang, M.5
Tseng, G.-N.6
-
113
-
-
77953037714
-
State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation
-
Wu, D., Delaloye, K., Zaydman, M. A., Nekouzadeh, A., Rudy, Y., and Cui, J. (2010a). State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation. J. Gen. Physiol. 135, 595-606.
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 595-606
-
-
Wu, D.1
Delaloye, K.2
Zaydman, M.A.3
Nekouzadeh, A.4
Rudy, Y.5
Cui, J.6
-
114
-
-
78649867712
-
KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function
-
Wu, D., Pan, H., Delaloye, K., and Cui, J. (2010b). KCNE1 remodels the voltage sensor of Kv7.1 to modulate channel function. Biophys. J. 99, 3599-3608.
-
(2010)
Biophys. J.
, vol.99
, pp. 3599-3608
-
-
Wu, D.1
Pan, H.2
Delaloye, K.3
Cui, J.4
-
115
-
-
67649949508
-
Location of the beta 4 transmembrane helices in the BK potassium channel
-
Wu, R. S., Chudasama, N., Zakharov, S. I., Doshi, D., Motoike, H., Liu, G., Yao, Y., Niu, X., Deng, S. X., Landry, D. W., Karlin, A., and Marx, S. O. (2009). Location of the beta 4 transmembrane helices in the BK potassium channel. J. Neurosci. 29, 8321-8328.
-
(2009)
J. Neurosci.
, vol.29
, pp. 8321-8328
-
-
Wu, R.S.1
Chudasama, N.2
Zakharov, S.I.3
Doshi, D.4
Motoike, H.5
Liu, G.6
Yao, Y.7
Niu, X.8
Deng, S.X.9
Landry, D.W.10
Karlin, A.11
Marx, S.O.12
-
116
-
-
78049465933
-
The BK potassium channel in the vascular smooth muscle and kidney: alpha- and beta-subunits
-
Wu, R. S., and Marx, S. O. (2010). The BK potassium channel in the vascular smooth muscle and kidney: alpha- and beta-subunits. Kidney Int. 78, 963-974.
-
(2010)
Kidney Int.
, vol.78
, pp. 963-974
-
-
Wu, R.S.1
Marx, S.O.2
-
117
-
-
0345298282
-
2+- and voltagedependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells
-
2+- and voltagedependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells. J. Neurosci. 19, 5255-5264.
-
(1999)
J. Neurosci.
, vol.19
, pp. 5255-5264
-
-
Xia, X.M.1
Ding, J.P.2
Lingle, C.J.3
-
118
-
-
0037327215
-
Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues
-
Xia, X. M., Ding, J. P., and Lingle, C. J. (2003). Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues. J. Gen. Physiol. 121, 125-148.
-
(2003)
J. Gen. Physiol.
, vol.121
, pp. 125-148
-
-
Xia, X.M.1
Ding, J.P.2
Lingle, C.J.3
-
119
-
-
0034234522
-
2+-activated, voltagedependent BK currents: consequences of rapid inactivation by a novel beta subunit
-
2+-activated, voltagedependent BK currents: consequences of rapid inactivation by a novel beta subunit. J. Neurosci. 20, 4890-4903.
-
(2000)
J. Neurosci.
, vol.20
, pp. 4890-4903
-
-
Xia, X.M.1
Ding, J.P.2
Zeng, X.H.3
Duan, K.L.4
Lingle, C.J.5
-
120
-
-
44349127924
-
KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains
-
Xu, X., Jiang, M., Hsu, K.-L., Zhang, M., and Tseng, G.-N. (2008). KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains. J. Gen. Physiol. 131, 589-603.
-
(2008)
J. Gen. Physiol.
, vol.131
, pp. 589-603
-
-
Xu, X.1
Jiang, M.2
Hsu, K.-L.3
Zhang, M.4
Tseng, G.-N.5
-
121
-
-
77954954506
-
LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium
-
Yan, J., and Aldrich, R. W. (2010). LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 466, 513-516.
-
(2010)
Nature
, vol.466
, pp. 513-516
-
-
Yan, J.1
Aldrich, R.W.2
-
122
-
-
82755195901
-
LRRC52 (leucine-rich- repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel
-
Yang, C., Zeng, X.-H., Zhou, Y., Xia, X.-M., and Lingle, C. J. (2011). LRRC52 (leucine-rich- repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc. Natl. Acad. Sci. U.S.A. 108, 19419-19424.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 19419-19424
-
-
Yang, C.1
Zeng, X.-H.2
Zhou, Y.3
Xia, X.-M.4
Lingle, C.J.5
-
124
-
-
0032408075
-
Single-channel properties of IKs potassium channels
-
Yang, Y., and Sigworth, F. J. (1998). Single-channel properties of IKs potassium channels. J. Gen. Physiol. 112, 665-678.
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 665-678
-
-
Yang, Y.1
Sigworth, F.J.2
-
125
-
-
0032417420
-
The moving parts of voltage-gated ion channels
-
Yellen, G. (1998). The moving parts of voltage-gated ion channels. Q. Rev. Biophys. 31, 239-295.
-
(1998)
Q. Rev. Biophys.
, vol.31
, pp. 239-295
-
-
Yellen, G.1
-
126
-
-
0028140472
-
Shaker potassium channel gating. III: Evaluation of kinetic models for activation
-
Zagotta,W. N.,Hoshi,T.,andAldrich,R. W. (1994). Shaker potassium channel gating. III: Evaluation of kinetic models for activation. J. Gen. Physiol. 103, 321-362.
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 321-362
-
-
Zagotta, W.N.1
Hoshi, T.2
Aldrich, R.W.3
-
127
-
-
78649758166
-
Locations of the Beta2 transmembrane helices in the BK potassium channel
-
Boston, MA
-
Zakharov, S. I., Wu, R. S., Liu, G., Motoike, H., Karlin, A., and Marx, S. O. (2009). "Locations of the Beta2 transmembrane helices in the BK potassium channel," in 53rd Annual Biophysical Society Meeting, Boston, MA.
-
(2009)
53rd Annual Biophysical Society Meeting
-
-
Zakharov, S.I.1
Wu, R.S.2
Liu, G.3
Motoike, H.4
Karlin, A.5
Marx, S.O.6
-
128
-
-
0038103596
-
Redox-sensitive extracellular gates formed by auxiliary beta subunits of calcium-activated potassium channels
-
Zeng, X. H., Xia, X. M., and Lingle, C. J. (2003). Redox-sensitive extracellular gates formed by auxiliary beta subunits of calcium-activated potassium channels. Nat. Struct. Biol. 10, 448-454.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 448-454
-
-
Zeng, X.H.1
Xia, X.M.2
Lingle, C.J.3
-
129
-
-
64549088411
-
N-terminal inactivation domains of beta subunits are protected from trypsin digestion by binding within the antechamber of BK channels
-
Zhang, Z., Zeng, X. H., Xia, X. M., and Lingle, C. J. (2009). N-terminal inactivation domains of beta subunits are protected from trypsin digestion by binding within the antechamber of BK channels. J. Gen. Physiol. 133, 263-282.
-
(2009)
J. Gen. Physiol.
, vol.133
, pp. 263-282
-
-
Zhang, Z.1
Zeng, X.H.2
Xia, X.M.3
Lingle, C.J.4
-
130
-
-
33751112239
-
A limited access compartment between the pore domain and cytosolic domain of the BK channel
-
Zhang, Z., Zhou, Y., Ding, J. P., Xia, X. M.,and Lingle,C. J. (2006).A limited access compartment between the pore domain and cytosolic domain of the BK channel. J. Neurosci. 26, 11833-11843.
-
(2006)
J. Neurosci
, vol.26
, pp. 11833-11843
-
-
Zhang, Z.1
Zhou, Y.2
Ding, J.P.3
Xia, X.M.4
Lingle, C.J.5
|