MinK residues line a potassium channel pore

Neuron

Volumn 16, Issue 3, 1996, Pages 571-577

  Wang, Ke Wei ^a   Tai, Kwok Keung ^a   Goldstein, Steve A N ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; POTASSIUM CHANNEL; POTASSIUM ION; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; BINDING SITE; CHANNEL GATING; GENE MUTATION; INHIBITION KINETICS; ION CONDUCTANCE; MEMBRANE BINDING; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029939875     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80076-8     Document Type: Article

References (42)

1. Akabas, M.H., Stauffer, D.A., Xu, M., and Karlin, A. (1992). Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258, 307-310.
2. Akabas, M.H., Kaufmann, C., Archdeacon, P., and Karlin, A. (1994a). Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit. Neuron 13, 919-927.
3. Akabas, M.H., Kaufmann, C., Cook, T.A., and Archdeacon, P. (1994b). Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 269, 14865-14868.
4. Armstrong, C.M. (1969). Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons. J. Gen. Physiol 54, 553-575.
5. - channels. Nature 365, 850-852.
6. Blumenthal, E.M., and Kaczmarek, L.K. (1992). Modulation by cAMP of a slowly activating potassium channel expressed in Xenopus oocytes. J. Neurosci 12, 290-296.
7. Blumenthal, E.M., and Kaczmarek, L.K. (1994). The minK potassium channel exists in functional and nonfunctional forms when expressed in the plasma membrane of Xenopus oocytes. J. Neurosci 14, 3097-3105.
8. Busch, A.E., Varnum, M.D., North, R.A., and Adelman, J.P. (1992a). An amino acid mutation in a potassium channel that prevents inhibition by protein kinase C. Science 255, 1705-1707.
9. Busch, A.E., Kavanaugh, M.P., Varnum, M.D., Adelman, J.P., and North, R.A. (1992b). Regulation by second messengers of the slowly activating, voltage-dependent potassium current expressed in Xenopus oocytes. J. Physiol. 450, 491-502.
10. Busch, A.E., Waldegger, S., Herzer, T., Raber, G., Gulbins, E., Takumi, T., Moriyoshi, K., Nakanishi, S., and Lang, F. (1995). Molecular basis of IsK protein regulation by oxidation or chelation. J. Biol. Chem. 270, 3638-3641.
11. Folander, K., Smith, J.S., Antanavage, J., Bennett, C., Stein, R.B., and Swanson, R. (1990). Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus. Proc. Natl. Acad. Sci. USA 87, 2975-2979.
12. + channel protein in mammalian cells and immunolocalization in guinea pig heart. Circ. Res. 73, 968-973.
13. + current in guinea pig sino-atrial node and transfected HEK-293 cells. Biophys. J 66, A143.
14. + channel alter ion selectivity and open-channel block. Neuron 7, 403-408.
15. + channel expressed from a synthetic gene. Biochemistry 30, 3341-3346.
16. + channel pore through mutant cycles with a peptide inhibitor. Science 268, 307-310.
17. Hille, B. (1992). Ionic Channels of Excitable Membranes, 2nd Edition (Sunderland, MA: Sinauer).
18. + channel in mouse heart. EMBO J. 10, 2805-2811.
19. + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys. J. 68, 900-905.
20. Lau, Y.T., Yassin, R.R., and Horowitz, S.B. (1988). Potassium salt microinjection into Xenopus oocytes mimics gonadotropin treatment. Science 240, 1321-1323.
21. Lesage, F., Attali, B., Lakey, J., Honore, E., Romey, G., Faurobert, E., Lazdunski, M., and Barhanin, J. (1993). Are Xenopus oocytes unique in displaying functional IsK channel heterologous expression? Recept. Channels 1, 143-152.
22. + channel. J. Gen. Physiol. 91, 335-349.
23. + channels. Science 250, 276-279.
24. + secretion in vestibular dark cells. Am. J. Physiol. 267, C857-C864.
25. + channel-blocking peptides. Neuron 15, 5-10.
26. Murai, T., Kakizuka, A., Takumi, T., Ohkubo, H., and Nakanishi, S. (1989). Molecular cloning and sequence analysis of human genomic DNA encoding a novel membrane protein which exhibits a slowly activating potassium channel activity. Biochem. Biophys. Res. Comm. 161, 176-181.
27. + pore structure revealed by reporter cysteines at inner and outer surfaces. Neuron 14, 1055-1063.
28. Sakagami, M., Fukazawa, K., Matsunaga, T., Fujita, H., Mori, N., Takumi, T., Ohkubo, H., and Nakanishi, S. (1991). Cellular localization of rat Isk protein in the stria vascularis by immunohistochemical observation. Hearing Res. 56, 168-172.
29. Shimbo, K., Brassard, D.L., Lamb, R.A., and Pinto, L.H. (1995). Viral and cellular small integral membrane proteins can modify ion channels endogenous to Xenopus oocytes. Biophys. J. 69, 1819-1829.
30. Stauffer, D.A., and Karlin, A. (1994). Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates. Biochemistry 33, 6840-6849.
31. + channel. Semin. Neurosci. 5, 117-124.
32. Tai, K.-K., Wang, K.-K., and Goldstein, S.A.N. (1996). Scanning cysteine mutagenesis implicates both minK and non-minK protein in pore formation. Biophys. J. 70, A151.
33. Takumi, T., Ohkubo, H., and Nakanishi, S. (1988). Cloning of a membrane protein that induces a slow voltage-gated potassium current. Science 242, 1042-1045.
34. Takumi, T., Moriyoshi, K., Aramori, I., Ishii, T., Oiki, S., Okada, Y., Ohkubo, H., and Nakanishi, S. (1991). Alteration of channel activities and gating by mutations of slow ISK potassium channel. J. Biol. Chem. 266, 22192-22198.
35. Tzounopoulos, T., Maylie, J., and Adelman, J. (1995a). Induction of endogenous channels by high levels of heterologous membrane proteins in Xenopus oocytes. Biophys. J. 69, 904-908.
36. Tzounopoulos, T., Guy, H.R., Durell, S., Adelman, J.P., and Maylie, J. (1995b). minK channels form by assembly of at least 14 subunits. Proc. Natl. Acad. Sci. USA 92, 9593-9597.
37. Varnum, M.D., Busch, A.E., Bond, C.T., Maylie, J., and Adelman, J.P. (1993). The min K channel underlies the cardiac potassium current IKs and mediates species-specific responses to protein kinase C. Proc. Natl. Acad. Sci. USA 90, 11528-11532.
38. Wang, K.-W., and Goldstein, S.A.N. (1995). Subunit composition of minK potassium channels. Neuron 14, 1303-1309.
39. Xu, M., and Akabas, M.H. (1993). Amino acids lining the channel of the γ-aminobutyric acid type A receptor identified by cysteine substitution. J. Biol. Chem. 268, 21505-21508.
40. Yang, Y., and Sigworth, F.J. (1995). The conductance of minK 'channels' is very small. Biophys. J. 68, A22.
41. Yeh, T.S., Morley, G.E., Taffet, S.M., Delmar, M., and Anumonwo, J.M.B. (1994). Intracellular acidification inhibits murine IsK. Biophys. J. 66, A143.
42. + channel. Science 251, 939-942.