KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval

Heart Rhythm

Volumn 4, Issue 12, 2007, Pages 1532-1541

  Lundby, Alicia ^a   Ravn, Lasse Steen ^b   Svendsen, Jesper Hastrup ^b   Olesen, Søren Peter ^a   Schmitt, Nicole ^a  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b Copenhagen University Hospital ^*  (Denmark)

Author keywords

Arrhythmia; Atrial fibrillation; KCNE1; KCNE2; KCNQ1; Kv7.1; Potassium channel; QT interval; Two electrode voltage clamp

Indexed keywords

ARGININE; GENOMIC DNA; GLUTAMINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; CHANNEL GATING; CHO CELL; CONTROLLED STUDY; DNA ISOLATION; ELECTROCARDIOGRAPHY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPE PHENOTYPE CORRELATION; HEART ATRIUM FIBRILLATION; HEART DEPOLARIZATION; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MAMMAL CELL; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; RR INTERVAL; SINGLE STRAND CONFORMATION POLYMORPHISM; XENOPUS LAEVIS;

AGED, 80 AND OVER; ANIMALS; ATRIAL FIBRILLATION; CARDIAC ELECTROPHYSIOLOGY; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; KCNQ1 POTASSIUM CHANNEL; MUTATION; OOCYTES; PHENOTYPE; XENOPUS LAEVIS;

EID: 36549055058     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2007.07.022     Document Type: Article

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