메뉴 건너뛰기




Volumn 133, Issue 3, 2009, Pages 263-282

N-terminal inactivation domains of βsubunits are protected from trypsin digestion by binding within the antechamber of BK channels

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; TRYPSIN;

EID: 64549088411     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200810079     Document Type: Article
Times cited : (10)

References (25)
  • 1
    • 31744435788 scopus 로고    scopus 로고
    • Direct observation of a preinactivated, open state in BK channels with B2 subunits
    • Benzinger , G.R. , X.M. Xia , and CJ. Lingle . 2006 . Direct observation of a preinactivated, open state in BK channels with B2 subunits. J. Gen. Physiol. 127 : 119 - 131 .
    • (2006) J. Gen. Physiol , vol.127 , pp. 119-131
    • Benzinger, G.R.1    Xia, X.M.2    Lingle, C.J.3
  • 2
    • 0031982539 scopus 로고    scopus 로고
    • Inactivating BK channels in rat chromaff n cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits
    • Ding , J.P. , Z.W. Li , and CJ. Lingle . 1998 . Inactivating BK channels in rat chromaff n cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits. Biophys. J. 74 : 268 - 289 .
    • (1998) Biophys. J , vol.74 , pp. 268-289
    • Ding, J.P.1    Li, Z.W.2    Lingle, C.J.3
  • 4
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • Hamill , O.P. , A. Marty , E. Neher , B. Sakmann , and FJ. Sigworth . 1981 . Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391 : 85 - 100 .
    • (1981) Pflugers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 5
    • 0037198626 scopus 로고    scopus 로고
    • Crystal structure and mechanism of a calcium-gated potas- sium channel
    • Jiang , Y , A. Lee , J. Chen , M. Cadene , B.T. Chait , and R. MacKinnon . 2002 . Crystal structure and mechanism of a calcium-gated potas- sium channel. Nature . 417 : 515 - 522 .
    • (2002) Nature , vol.417 , pp. 515-522
    • Jiang, Y.1    Lee, A.2    Chen, J.3    Cadene, M.4    Chait, B.T.5    MacKinnon, R.6
  • 7
    • 34848911947 scopus 로고    scopus 로고
    • Studying the structural properties of polyalanine and poly- glutamine peptides
    • Leitgeb , B. , A. Kerenyi , F. Bogar , G. Paragi , B. Penke , and G. Rakhely 2007 . Studying the structural properties of polyalanine and poly- glutamine peptides. J. Mol. Model. 13 : 1141 - 1150 .
    • (2007) J. Mol. Model , vol.13 , pp. 1141-1150
    • Leitgeb, B.1    Kerenyi, A.2    Bogar, F.3    Paragi, G.4    Penke, B.5    Rakhely, G.6
  • 8
    • 3142682254 scopus 로고    scopus 로고
    • Unique inner pore properties of BK channels revealed by quaternary ammonium block
    • Li , W. , and R.W. Aldrich . 2004 . Unique inner pore properties of BK channels revealed by quaternary ammonium block. J. Gen. Physiol. 124 : 43 - 57 .
    • (2004) J. Gen. Physiol , vol.124 , pp. 43-57
    • Li, W.1    Aldrich, R.W.2
  • 9
    • 0034967181 scopus 로고    scopus 로고
    • Inactivation of BK channels mediated by the N-terminus of the B3b auxiliary subunit involves a two-step mechanism: Possible separation of binding and blockade
    • Lingle , CJ. , X.-H. Zeng , J.-P Ding , and X.-M. Xia . 2001 . Inactivation of BK channels mediated by the N-terminus of the B3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockade. J. Gen. Physiol. 117 : 583 - 605 .
    • (2001) J. Gen. Physiol , vol.117 , pp. 583-605
    • Lingle, C.J.1    Zeng, X.-H.2    Ding, J.-P.3    Xia, X.-M.4
  • 11
    • 0030748370 scopus 로고    scopus 로고
    • The cytosolic inactivation domains of BK channels in rat chromaff n cells do not behave like simple, open-channel blockers
    • Solaro , CR. , J.P Ding , Z.W. Li , and CJ. Lingle . 1997 . The cytosolic inactivation domains of BK channels in rat chromaff n cells do not behave like simple, open-channel blockers. Biophys. J. 73 : 819 - 830 .
    • (1997) Biophys. J , vol.73 , pp. 819-830
    • Solaro, C.R.1    Ding, J.P.2    Li, Z.W.3    Lingle, C.J.4
  • 12
    • 0034725701 scopus 로고    scopus 로고
    • + channel. J. Biol. Chem. 275 : 23211 - 23218 .
    • + channel. J. Biol. Chem. 275 : 23211 - 23218 .
  • 13
    • 34548757409 scopus 로고    scopus 로고
    • Quantitative character- ization of intrinsic disorder in polyglutamine: Insights from analy- sis based on polymer theories
    • Vitalis , A. , X. Wang , and R.V. Pappu . 2007 . Quantitative character- ization of intrinsic disorder in polyglutamine: insights from analy- sis based on polymer theories. Biophys. J. 93 : 1923 - 1937 .
    • (2007) Biophys. J , vol.93 , pp. 1923-1937
    • Vitalis, A.1    Wang, X.2    Pappu, R.V.3
  • 15
    • 33645281939 scopus 로고    scopus 로고
    • Characterizing the conformational ensemble of monomeric poly- glutamine
    • Wang , X. , A. Vitalis , M.A Wyczalkowski , and RV. Pappu . 2006 . Characterizing the conformational ensemble of monomeric poly- glutamine. Proteins . 63 : 297 - 311 .
    • (2006) Proteins , vol.63 , pp. 297-311
    • Wang, X.1    Vitalis, A.2    Wyczalkowski, M.A.3    Pappu, R.V.4
  • 17
    • 33748094494 scopus 로고    scopus 로고
    • State-independent block of BK channels by an intracellular quaternary ammonium
    • Wilkens , CM. , and R.W. Aldrich . 2006 . State-independent block of BK channels by an intracellular quaternary ammonium. J. Gen. Physiol. 128 : 347 - 364 .
    • (2006) J. Gen. Physiol , vol.128 , pp. 347-364
    • Wilkens, C.M.1    Aldrich, R.W.2
  • 18
    • 0345298282 scopus 로고    scopus 로고
    • 2+ - and voltage-dependent BK channels in adre- nal chromaff n cells and rat insulinoma tumor cells
    • 2+ - and voltage-dependent BK channels in adre- nal chromaff n cells and rat insulinoma tumor cells. J. Neurosci. 19 : 5255 - 5264 .
    • (1999) J. Neurosci , vol.19 , pp. 5255-5264
    • Xia, X.-M.1    Ding, J.P.2    Lingle, C.J.3
  • 19
    • 0034234522 scopus 로고    scopus 로고
    • 2+ -activated, voltage-dependent BK currents: Consequences of rapid inactiva- tion by a novel B subunit
    • 2+ -activated, voltage-dependent BK currents: consequences of rapid inactiva- tion by a novel B subunit. J. Neurosci. 20 : 4890 - 4903 .
    • (2000) J. Neurosci , vol.20 , pp. 4890-4903
    • Xia, X.-M.1    Ding, J.-P.2    Zeng, X.-H.3    Duan, K.-L.4    Lingle, C.J.5
  • 20
    • 0037158754 scopus 로고    scopus 로고
    • Multiple regulatory sites in large-conductance calcium-activated potassium channels
    • Xia , X.-M. , X.-H. Zeng , and CJ. Lingle . 2002 . Multiple regulatory sites in large-conductance calcium-activated potassium channels. Nature . 418 : 880 - 884 .
    • (2002) Nature , vol.418 , pp. 880-884
    • Xia, X.-M.1    Zeng, X.-H.2    Lingle, C.J.3
  • 21
    • 0037327215 scopus 로고    scopus 로고
    • 2 terminus of the B2 auxiliary subunit: An essential role of a terminal peptide segment of three hydrophobic resi- dues
    • 2 terminus of the B2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic resi- dues. J. Gen. Physiol. 121 : 125 - 148 .
    • (2003) J. Gen. Physiol , vol.121 , pp. 125-148
    • Xia, X.-M.1    Ding, J.P.2    Lingle, C.J.3
  • 22
    • 3042639555 scopus 로고    scopus 로고
    • Ligand-dependent acti- vation of Slo family channels is defined by interchangeable cyto- solic domains
    • Xia , X.-M. , X. Zhang , and CJ. Lingle . 2004 . Ligand-dependent acti- vation of Slo family channels is defined by interchangeable cyto- solic domains. J. Neurosci. 24 : 5585 - 5591 .
    • (2004) J. Neurosci , vol.24 , pp. 5585-5591
    • Xia, X.-M.1    Zhang, X.2    Lingle, C.J.3
  • 23
    • 48749112359 scopus 로고    scopus 로고
    • Species-specif c differ- ences among KCNMB3 BK B3 auxiliary subunits: Some B3 variants may be primate-specif c subunits
    • Zeng , X. , X.M. Xia , and CJ. Lingle . 2008 . Species-specif c differ- ences among KCNMB3 BK B3 auxiliary subunits: some B3 variants may be primate-specif c subunits. J. Gen. Physiol. 132 : 115 - 129 .
    • (2008) J. Gen. Physiol , vol.132 , pp. 115-129
    • Zeng, X.1    Xia, X.M.2    Lingle, C.J.3
  • 24
    • 33751112239 scopus 로고    scopus 로고
    • A lim- ited access compartment between the pore domain and cytosolic domain of the BK channel
    • Zhang , Z. , Y Zhou , J.P. Ding , X.M. Xia , and CJ. Lingle . 2006 . A lim- ited access compartment between the pore domain and cytosolic domain of the BK channel. J. Neurosci. 26 : 11833 - 11843 .
    • (2006) J. Neurosci , vol.26 , pp. 11833-11843
    • Zhang, Z.1    Zhou, Y.2    Ding, J.P.3    Xia, X.M.4    Lingle, C.J.5
  • 25
    • 0035822048 scopus 로고    scopus 로고
    • Potassium channel receptor site for the inactivation gate and qua- ternary amine inhibitors
    • Zhou , M. , J.H. Morais-Cabral , S. Mann , and R MacKinnon . 2001 . Potassium channel receptor site for the inactivation gate and qua- ternary amine inhibitors. Nature . 411 : 657 - 661 . 283-294
    • (2001) Nature , vol.411
    • Zhou, M.1    Morais-Cabral, J.H.2    Mann, S.3    MacKinnon, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.