Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies

International Journal of Hyperthermia

Volumn 28, Issue 6, 2012, Pages 509-517

  Eppink, Berina ^a   Krawczyk, Przemek M ^b   Stap, Jan ^b   Kanaar, Roland ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

DNA double strand breaks; Heat shock protein inhibitors; Homologous recombination; Hyperthermia; PARP inhibitors

Indexed keywords

ALVESPIMYCIN; ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; CHECKPOINT KINASE 1; CISPLATIN; FANCONI ANEMIA GROUP A PROTEIN; HEAT SHOCK PROTEIN 100; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; RAD51 PROTEIN; XRCC3 PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER THERAPY; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL VIABILITY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HEAT SENSITIVITY; HEAT SHOCK; HEAT STRESS; HOMOLOGOUS RECOMBINATION; HUMAN; HYPERTHERMIC THERAPY; NONHUMAN; SINGLE STRANDED DNA BREAK;

DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR-DEFICIENCY DISORDERS; HEAT-SHOCK RESPONSE; HOMOLOGOUS RECOMBINATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYPERTHERMIA, INDUCED; POLY(ADP-RIBOSE) POLYMERASES;

EID: 84865332443     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656736.2012.695427     Document Type: Article

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