Delaying S-phase progression rescues cells from heat-induced S-phase hypertoxicity

Journal of Cellular Physiology

Volumn 187, Issue 2, 2001, Pages 236-243

  Vanderwaal, R P ^a   Griffith, C L ^a   Wright, W D ^a   Borrelli, M J ^b   Roti Roti, J L ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WILLIAM BEAUMONT HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; NUCLEAR PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL KILLING; CELL NUCLEUS MATRIX; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOTOXICITY; DNA DAMAGE; DNA METABOLISM; DNA REPLICATION; HEAT SHOCK; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DENATURATION; STRESS;

APHIDICOLIN; CELL DIVISION; CELL NUCLEUS; CELL SURVIVAL; CYCLIN A; DNA REPLICATION; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ENZYME INHIBITORS; EXODEOXYRIBONUCLEASES; FUNGAL PROTEINS; HEAT-SHOCK RESPONSE; HELA CELLS; HUMANS; PROLIFERATING CELL NUCLEAR ANTIGEN; REPLICATION PROTEIN A; S PHASE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0035057404     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.1073     Document Type: Article

References (42)

1. Sensitivity of different cell lines and of different phases in the cell cycle of hyperthermia
2. The effect of hyperthermia on the protein content of HeLa cell nuclei: A flow cytometric analysis
3. Excess protein in nuclei isolated from heat-shocked cells results from a reduced extractability of nuclear proteins
4. Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: Association with DNA replication sites
5. Heat induced protein denaturation in the particulate fraction of HeLa S3 cells: Effect of thermotolerance
6. Possible role of localize protein denaturation in the mechanism of induction of thermotolerance by heat, sodium-arsenite and ethanol
7. Content of nonhistone protein in nuclei after hyperthermic treatment
8. Formation of a complex between nucleolin and replication protein A after cell stress prevents initiation of DNA replication
9. Heat-induced lethality and chromosomal damage in synchronized Chinese hamster cell streated with 5-bromodeoxyuridine
10. Hyperthermic radio-sensitization of synchronous Chinese hamster cells: Relationship between lethality and chromosomal aberrations
11. Cell killing, chromosomal aberrations and division delay as thermal sensitivity is modified during the cycle
12. Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex
13. Binding of the protein disulfide isomerase isoform ERp 60 to the nuclear matrix-associated regions of DNA
14. Accelerated G1-transit following transient inhibition of DNA replication is dependent on two processes
15. Alterations in nuclear protein mass and macromolecular synthesis following heat shock
16. The relationship of increased nuclear protein content induced by hyperthermia to killing of HeLa S3 cells
17. Thermotolerance in mammalian cells: Protein denaturation and aggregation, and stress proteins
18. Thermal protein denaturation and protein aggregation in cells made thermotolerant by various chemicals: Role of heat shock proteins
19. The effects of hyperthermia on mammalian cell structure and function
20. Initial characterization of heat-induced nuclear proteins in HeLa cells
21. Mechanism(s) of heat killing: Accumulation of nascent polypeptides in the nucleus?
22. Protein denaturation during heat shock
23. Involvement of membranes in cellular responses to hyperthermia
24. Uncoupling of M-phase kinase activation from the completion of S-phase by heat shock
25. Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese hamster cell lines
26. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double strand breaks
27. Hsp70 and hsp40 chaperone activites in the cytoplasm and the nucleus of mammalian cells
28. Hyperthermia
29. Immunolocalization in three dimensions: Immunogold staining of cytoskeletal and nuclear matrix proteins in resinless electron microscopy sections
30. The mammalian Mre11-Rad50-Nbs1 protein complex: Integration of functions in the cellular DNA-damage response
31. The kinetics of increase in chromatin protein content in heated cells: A possible role in cell killing
32. The effects of alcohols, procaine and hyperthermia on the protein content of nuclei and chromatin
33. The effect of hyperthermia on cellular macromolecules
34. Heat-shock-induced changes in nuclear protein and cell killing in thermotolerant HeLa cells
35. Nuclear matrix as a target for hyperthermic killing of cancer cells
36. Localization of cyclin A at the sites of cellular DNA replication
37. Spontaneous premature chromosome condensation, micronucleus formation, and non-apoptotic cell death in heated HeLa S3 cells: Ultrastructural observations
38. Heat-induced modifications in the association of specific proteins with the nuclear matrix
39. A comparison of the modes and kinetics of heat-induced cell killing in HeLa and L5178Y cells
40. Mammalian stress response: Cell physiology structure/function of stress proteins and implications for medicine and disease
41. Replication protein A: A heterotrimeric single-stranded DNA-binding protein required for Eukaryotic DNA metabolism
42. Fluorescent methods for studying subnuclear particles