메뉴 건너뛰기




Volumn 57, Issue 2, 2003, Pages 553-562

Selective targeting of homologous DNA recombination repair by gemcitabine

Author keywords

Double strand break repair; Homologous recombination; Rad51

Indexed keywords

CELLS; DNA; RADIOTHERAPY;

EID: 0041881891     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(03)00503-0     Document Type: Article
Times cited : (76)

References (37)
  • 1
    • 0028240063 scopus 로고
    • Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
    • Shewach D.S., Hahn T.M., Chang E., et al. Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Res. 54:1994;3218-3223.
    • (1994) Cancer Res , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3
  • 2
    • 0030005273 scopus 로고    scopus 로고
    • Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine
    • Lawrence T.S., Chang E.Y., Hahn T.M., et al. Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine. Int J Radiat Oncol Biol Phys. 34:1996;867-872.
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , pp. 867-872
    • Lawrence, T.S.1    Chang, E.Y.2    Hahn, T.M.3
  • 3
    • 0030751501 scopus 로고    scopus 로고
    • Enhancement of radiation-induced regrowth delay by gemcitabine in a human tumor xenograft model
    • Joschko M.A., Webster L.K., Groves J., et al. Enhancement of radiation-induced regrowth delay by gemcitabine in a human tumor xenograft model. Radiat Oncol Investig. 5:1997;62-71.
    • (1997) Radiat Oncol Investig , vol.5 , pp. 62-71
    • Joschko, M.A.1    Webster, L.K.2    Groves, J.3
  • 4
    • 0032948219 scopus 로고    scopus 로고
    • Enhancement of tumor radioresponse in vivo by gemcitabine
    • Milas L., Fujii T., Hunter N., et al. Enhancement of tumor radioresponse in vivo by gemcitabine. Cancer Res. 59:1999;107-114.
    • (1999) Cancer Res , vol.59 , pp. 107-114
    • Milas, L.1    Fujii, T.2    Hunter, N.3
  • 5
    • 0033194695 scopus 로고    scopus 로고
    • Chemo-radiotherapy: Radiosensitizing nucleoside analogues (review)
    • Gregoire V., Hittelman W.N., Rosier J.F., et al. Chemo-radiotherapy Radiosensitizing nucleoside analogues (review) . Oncol Rep. 6:1999;949-957.
    • (1999) Oncol Rep , vol.6 , pp. 949-957
    • Gregoire, V.1    Hittelman, W.N.2    Rosier, J.F.3
  • 6
    • 0031230507 scopus 로고    scopus 로고
    • Molecular processes and radiosensitivity
    • Zdzienicka M.Z. Molecular processes and radiosensitivity. Strahlenther Onkol. 173:1997;457-461.
    • (1997) Strahlenther Onkol , vol.173 , pp. 457-461
    • Zdzienicka, M.Z.1
  • 7
    • 0035866412 scopus 로고    scopus 로고
    • End-joining deficiency and radiosensitization induced by gemcitabine
    • Van Putten J.W.G., Groen H.J.M., Smid K., et al. End-joining deficiency and radiosensitization induced by gemcitabine. Cancer Res. 61:2001;1585-1591.
    • (2001) Cancer Res , vol.61 , pp. 1585-1591
    • Van Putten, J.W.G.1    Groen, H.J.M.2    Smid, K.3
  • 8
    • 0028839329 scopus 로고
    • Radiosensitization of human tumor cells by gemcitabine in vitro
    • Shewach D.S., Lawrence T.S. Radiosensitization of human tumor cells by gemcitabine in vitro. Semin Oncol. 22:1995;68-71.
    • (1995) Semin Oncol , vol.22 , pp. 68-71
    • Shewach, D.S.1    Lawrence, T.S.2
  • 9
    • 0034059127 scopus 로고    scopus 로고
    • Expression of ERCC1 antisense RNA abrogates gemcitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair
    • Yang L.Y., Li L., Jiang H., et al. Expression of ERCC1 antisense RNA abrogates gemcitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair. Clin Cancer Res. 6:2000;773-781.
    • (2000) Clin Cancer Res , vol.6 , pp. 773-781
    • Yang, L.Y.1    Li, L.2    Jiang, H.3
  • 10
    • 0034706917 scopus 로고    scopus 로고
    • Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants
    • Asaad N.A., Zeng Z.C., Guan J., et al. Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells Reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants . Oncogene. 19:2000;5788-5800.
    • (2000) Oncogene , vol.19 , pp. 5788-5800
    • Asaad, N.A.1    Zeng, Z.C.2    Guan, J.3
  • 11
    • 0033065174 scopus 로고    scopus 로고
    • The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells
    • Cui X., Brenneman M., Meyne J., et al. The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells. Mutat Res. 434:1999;75-88.
    • (1999) Mutat Res , vol.434 , pp. 75-88
    • Cui, X.1    Brenneman, M.2    Meyne, J.3
  • 12
    • 0032061317 scopus 로고    scopus 로고
    • XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
    • Liu N., Lamerdin J.E., Tebbs R.S., et al. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol Cell. 1:1998;783-793.
    • (1998) Mol Cell , vol.1 , pp. 783-793
    • Liu, N.1    Lamerdin, J.E.2    Tebbs, R.S.3
  • 13
    • 45949121186 scopus 로고
    • Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells
    • Jones N.J., Cox R., Thacker J. Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells. Mutat Res. 183:1987;279-286.
    • (1987) Mutat Res , vol.183 , pp. 279-286
    • Jones, N.J.1    Cox, R.2    Thacker, J.3
  • 14
    • 0032126530 scopus 로고    scopus 로고
    • The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family
    • Cartwright R., Tambini C.E., Simpson P.J., et al. The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family. Nucleic Acids Res. 26:1998;3084-3089.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3084-3089
    • Cartwright, R.1    Tambini, C.E.2    Simpson, P.J.3
  • 15
    • 0031127146 scopus 로고    scopus 로고
    • The XRCC2 DNA repair gene: Identification of a positional candidate
    • Tambini C.E., George A.M., Rommens J.M., et al. The XRCC2 DNA repair gene Identification of a positional candidate . Genomics. 41:1997;84-92.
    • (1997) Genomics , vol.41 , pp. 84-92
    • Tambini, C.E.1    George, A.M.2    Rommens, J.M.3
  • 16
    • 0033598437 scopus 로고    scopus 로고
    • Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
    • Johnson R.D., Liu N., Jasin M. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination. Nature. 401:1999;397-399.
    • (1999) Nature , vol.401 , pp. 397-399
    • Johnson, R.D.1    Liu, N.2    Jasin, M.3
  • 17
    • 0023905947 scopus 로고
    • A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
    • Fuller L.F., Painter R.B. A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat Res. 193:1988;109-121.
    • (1988) Mutat Res , vol.193 , pp. 109-121
    • Fuller, L.F.1    Painter, R.B.2
  • 18
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce A.J., Johnson R.D., Thompson L.H., et al. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev. 13:1999;2633-2638.
    • (1999) Genes Dev , vol.13 , pp. 2633-2638
    • Pierce, A.J.1    Johnson, R.D.2    Thompson, L.H.3
  • 19
    • 0032803238 scopus 로고    scopus 로고
    • The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage
    • Kooistra R., Pastink A., Zonneveld J.B., et al. The Drosophila melanogaster DmRAD54 gene plays a crucial role in double-strand break repair after P-element excision and acts synergistically with Ku70 in the repair of X-ray damage. Mol Cell Biol. 19:1999;6269-6275.
    • (1999) Mol Cell Biol , vol.19 , pp. 6269-6275
    • Kooistra, R.1    Pastink, A.2    Zonneveld, J.B.3
  • 20
    • 0030948789 scopus 로고    scopus 로고
    • Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination
    • Essers J., Hendriks R.W., Swagemakers S.M., et al. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell. 89:1997;195-204.
    • (1997) Cell , vol.89 , pp. 195-204
    • Essers, J.1    Hendriks, R.W.2    Swagemakers, S.M.3
  • 21
    • 0034599981 scopus 로고    scopus 로고
    • Homologous and non-homologous recombination differentially affect DNA damage repair in mice
    • Essers J., Van Steeg H., De Wit J., et al. Homologous and non-homologous recombination differentially affect DNA damage repair in mice. EMBO J. 19:2000;1703-1710.
    • (2000) EMBO J , vol.19 , pp. 1703-1710
    • Essers, J.1    Van Steeg, H.2    De Wit, J.3
  • 22
    • 0028151464 scopus 로고
    • DNA damages processed by base excision repair: Biological consequences
    • Wallace S.S. DNA damages processed by base excision repair Biological consequences . Int J Radiat Biol. 66:1994;579-589.
    • (1994) Int J Radiat Biol , vol.66 , pp. 579-589
    • Wallace, S.S.1
  • 23
    • 0031773901 scopus 로고    scopus 로고
    • Enzymatic processing of radiation-induced free radical damage in DNA
    • Wallace S.S. Enzymatic processing of radiation-induced free radical damage in DNA. Radiat Res. 150:1998;S60-S79.
    • (1998) Radiat Res , vol.150
    • Wallace, S.S.1
  • 24
    • 0026651211 scopus 로고
    • A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges
    • Zdzienicka M.Z., Van der Schans G.P., Natarajan A.T., et al. A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges. Mutagenesis. 7:1992;265-269.
    • (1992) Mutagenesis , vol.7 , pp. 265-269
    • Zdzienicka, M.Z.1    Van Der Schans, G.P.2    Natarajan, A.T.3
  • 25
    • 0030863307 scopus 로고    scopus 로고
    • Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair
    • Cappelli E., Taylor R., Cevasco M., et al. Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair. J Biol Chem. 272:1997;23970-23975.
    • (1997) J Biol Chem , vol.272 , pp. 23970-23975
    • Cappelli, E.1    Taylor, R.2    Cevasco, M.3
  • 26
    • 0033514993 scopus 로고    scopus 로고
    • Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
    • Raderschall E., Golub E.I., Haaf T. Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc Natl Acad Sci USA. 96:1999;1921-1926.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1921-1926
    • Raderschall, E.1    Golub, E.I.2    Haaf, T.3
  • 27
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine
    • Heinemann V., Hertel L.W., Grindey G.B., et al. Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine. Cancer Res. 48:1988;4024-4031.
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3
  • 28
    • 0033781210 scopus 로고    scopus 로고
    • Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells
    • De Silva I.U., McHugh P.J., Clingen P.H., et al. Defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells. Mol Cell Biol. 20:2000;7980-7990.
    • (2000) Mol Cell Biol , vol.20 , pp. 7980-7990
    • De Silva, I.U.1    McHugh, P.J.2    Clingen, P.H.3
  • 29
    • 0035933877 scopus 로고    scopus 로고
    • XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding
    • O'Regan P., Wilson C., Townsend S., et al. XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding. J Biol Chem. 276:2001;22148-22153.
    • (2001) J Biol Chem , vol.276 , pp. 22148-22153
    • O'Regan, P.1    Wilson, C.2    Townsend, S.3
  • 30
    • 0035070587 scopus 로고    scopus 로고
    • Hyperthermic radiosensitization: Mode of action and clinical relevance
    • Kampinga H.H., Dikomey E. Hyperthermic radiosensitization Mode of action and clinical relevance . Int J Radiat Biol. 77:2001;399-408.
    • (2001) Int J Radiat Biol , vol.77 , pp. 399-408
    • Kampinga, H.H.1    Dikomey, E.2
  • 31
    • 0034710152 scopus 로고    scopus 로고
    • Rad51 accumulation at sites of DNA damage and in postreplicative chromatin
    • Tashiro S., Walter J., Shinohara A., et al. Rad51 accumulation at sites of DNA damage and in postreplicative chromatin. J Cell Biol. 150:2000;283-291.
    • (2000) J Cell Biol , vol.150 , pp. 283-291
    • Tashiro, S.1    Walter, J.2    Shinohara, A.3
  • 32
    • 0035802230 scopus 로고    scopus 로고
    • In vitro evidence for homologous recombinational repair in resistance to melphalan
    • Wang Z.M., Chen Z.P., Xu Z.Y., et al. In vitro evidence for homologous recombinational repair in resistance to melphalan. J Natl Cancer Inst. 93:2001;1473-1478.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1473-1478
    • Wang, Z.M.1    Chen, Z.P.2    Xu, Z.Y.3
  • 33
    • 0028957889 scopus 로고
    • Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes
    • Haaf T., Golub E.I., Reddy G., et al. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc Natl Acad Sci USA. 92:1995;2298-2302.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2298-2302
    • Haaf, T.1    Golub, E.I.2    Reddy, G.3
  • 34
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature. 411:2001;366-374.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.1
  • 35
    • 0031804603 scopus 로고    scopus 로고
    • Radiosensitizing potential of gemcitabine (2′,2′-difluoro-2′-deoxycytidine) within the cell cycle in vitro
    • Latz D., Fleckenstein K., Eble M., et al. Radiosensitizing potential of gemcitabine (2′,2′-difluoro-2′-deoxycytidine) within the cell cycle in vitro. Int J Radiat Oncol Biol Phys. 41:1998;875-882.
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , pp. 875-882
    • Latz, D.1    Fleckenstein, K.2    Eble, M.3
  • 36
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M., Sasaki M.S., Sonoda E., et al. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 17:1998;5497-5508.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3
  • 37
    • 0037090535 scopus 로고    scopus 로고
    • Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage
    • Essers J., Houtsmuller A.B., Van Veelen L., et al. Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J. 21:2002;2030-2037.
    • (2002) EMBO J , vol.21 , pp. 2030-2037
    • Essers, J.1    Houtsmuller, A.B.2    Van Veelen, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.