메뉴 건너뛰기




Volumn 9, Issue 10 I, 2003, Pages 3749-3755

Enhanced cell killing induced by the combination of radiation and the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin: A multitarget approach to radiosensitization

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HEAT SHOCK PROTEIN 90; PROTEIN; PROTEIN KINASE B; RAF PROTEIN; UNCLASSIFIED DRUG;

EID: 0141568014     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (107)

References (25)
  • 1
    • 0031550257 scopus 로고    scopus 로고
    • Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells
    • Pirollo, K. F., Hao, Z., Rait, A., Ho, C. W., and Chang, E. H. Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells. Biochem. Biophys. Res. Commun., 230: 196-201, 1997.
    • (1997) Biochem. Biophys. Res. Commun. , vol.230 , pp. 196-201
    • Pirollo, K.F.1    Hao, Z.2    Rait, A.3    Ho, C.W.4    Chang, E.H.5
  • 3
    • 0037089516 scopus 로고    scopus 로고
    • Inhibition of radiation-induced nuclear factor-κB activation by an anti-Ras single-chain antibody fragment: Lack of involvement in radiosensitization
    • Russell, J. S., Raju, U., Gumin, G. J., Lang, F. F., Wilson, D. R., Huet, T., and Tofilon, P. J. Inhibition of radiation-induced nuclear factor-κB activation by an anti-Ras single-chain antibody fragment: lack of involvement in radiosensitization. Cancer Res., 62: 2318-2326, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 2318-2326
    • Russell, J.S.1    Raju, U.2    Gumin, G.J.3    Lang, F.F.4    Wilson, D.R.5    Huet, T.6    Tofilon, P.J.7
  • 5
    • 0036219609 scopus 로고    scopus 로고
    • Hsp90 inhibitors as novel cancer chemotherapeutic agents
    • Neckers, L. Hsp90 inhibitors as novel cancer chemotherapeutic agents. Trends Mol. Med., 8: S55-S61, 2002.
    • (2002) Trends Mol. Med. , vol.8
    • Neckers, L.1
  • 7
    • 0033559619 scopus 로고    scopus 로고
    • Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene
    • Pietras, R. J., Poen, J. C., Gallardo, D., Wongvipat, P. N., Lee, H. J., and Slamon, D. J. Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene. Cancer Res., 59: 1347-1355, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 1347-1355
    • Pietras, R.J.1    Poen, J.C.2    Gallardo, D.3    Wongvipat, P.N.4    Lee, H.J.5    Slamon, D.J.6
  • 8
    • 0036091221 scopus 로고    scopus 로고
    • Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: A novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts
    • Neckers, L. Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: a novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res., 8: 986-993, 2002. Clin. Cancer Res., 8: 962-966, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 986-993
    • Neckers, L.1
  • 9
    • 0036098002 scopus 로고    scopus 로고
    • Neckers, L. Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: a novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res., 8: 986-993, 2002. Clin. Cancer Res., 8: 962-966, 2002.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 962-966
  • 10
    • 0021244486 scopus 로고
    • Mean inactivation dose: A useful concept for intercomparison of human cell survival curves
    • Fertil, B., Dertinger, H., Courdi, A., and Malaise, E. P. Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat. Res., 99: 73-84, 1984.
    • (1984) Radiat. Res. , vol.99 , pp. 73-84
    • Fertil, B.1    Dertinger, H.2    Courdi, A.3    Malaise, E.P.4
  • 12
    • 0035872396 scopus 로고    scopus 로고
    • Disruption of the EF-2 kinase/Hsp90 protein complex: A possible mechanism to inhibit glioblastoma by geldanamycin
    • Yang, J., Yang, J. M., Iannone, M., Shih, W. J., Lin, Y., and Hait, W. N. Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin. Cancer Res., 61: 4010-4016, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 4010-4016
    • Yang, J.1    Yang, J.M.2    Iannone, M.3    Shih, W.J.4    Lin, Y.5    Hait, W.N.6
  • 13
    • 0031875042 scopus 로고    scopus 로고
    • The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
    • Schulte, T. W., and Neckers, L. M. The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin. Cancer Chemother. Pharmacol., 42: 273-279, 1998.
    • (1998) Cancer Chemother. Pharmacol. , vol.42 , pp. 273-279
    • Schulte, T.W.1    Neckers, L.M.2
  • 14
    • 0035872442 scopus 로고    scopus 로고
    • Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis
    • Hostein, I., Robertson, D., DiStefano, F., Workman, P., and Clarke, P. A. Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. Cancer Res., 61: 4003-4009, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 4003-4009
    • Hostein, I.1    Robertson, D.2    DiStefano, F.3    Workman, P.4    Clarke, P.A.5
  • 15
    • 0034886833 scopus 로고    scopus 로고
    • Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: Sequence and tumor biology matters
    • Munster, P. N., Basso, A., Solit, D., Norton, L., and Rosen, N. Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. Clin. Cancer Res., 7: 2228-2236, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2155-2158
    • Munster, P.N.1    Basso, A.2    Solit, D.3    Norton, L.4    Rosen, N.5
  • 16
    • 0034890377 scopus 로고    scopus 로고
    • Munster, P. N., Basso, A., Solit, D., Norton, L., and Rosen, N. Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. Clin. Cancer Res., 7: 2228-2236, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2228-2236
  • 19
    • 0036606332 scopus 로고    scopus 로고
    • Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway
    • Munster, P. N., Marchion, D. C., Basso, A. D., and Rosen, N. Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway. Cancer Res., 62: 3132-3137, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 3132-3137
    • Munster, P.N.1    Marchion, D.C.2    Basso, A.D.3    Rosen, N.4
  • 20
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., Jr., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend, S.11    Fornace A.J., Jr.12    Kohn, K.W.13
  • 21
    • 0034800172 scopus 로고    scopus 로고
    • Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after γ-irradiation
    • Tezuka, M., Watanabe, H., Nakamura, S., Yu, D., Aung, W., Sasaki, T., Shibuya, H., and Miura, M. Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after γ-irradiation. Clin. Cancer Res., 7: 3206-3214, 2001.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3206-3214
    • Tezuka, M.1    Watanabe, H.2    Nakamura, S.3    Yu, D.4    Aung, W.5    Sasaki, T.6    Shibuya, H.7    Miura, M.8
  • 22
    • 0036568414 scopus 로고    scopus 로고
    • Independent prognostic significance of HER-2 oncoprotein expression in pNO prostate cancer undergoing curative radiotherapy
    • Fossa, A., Lilleby, W., Fossa, S. D. Gaudemack G., Torlakovic, G., and Berner, A. Independent prognostic significance of HER-2 oncoprotein expression in pNO prostate cancer undergoing curative radiotherapy. Int. J. Cancer, 99: 100-105, 2002.
    • (2002) Int. J. Cancer , vol.99 , pp. 100-105
    • Fossa, A.1    Lilleby, W.2    Fossa, S.D.3    Gaudemack, G.4    Torlakovic, G.5    Berner, A.6
  • 23
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Wash. DC), 235: 177-182, 1987.
    • (1987) Science (Wash. DC) , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 24
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer, P. J., Jin, J., and Woodgett, J. R. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J., 335: 1-13, 1998.
    • (1998) Biochem. J. , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 25
    • 0024363796 scopus 로고
    • Radioresistance induced by oncogenic transformation
    • Ling, C. C., and Endlich, B. Radioresistance induced by oncogenic transformation. Radiat. Res., 120: 267-279, 1989.
    • (1989) Radiat. Res. , vol.120 , pp. 267-279
    • Ling, C.C.1    Endlich, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.