-
1
-
-
0031550257
-
Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells
-
Pirollo, K. F., Hao, Z., Rait, A., Ho, C. W., and Chang, E. H. Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells. Biochem. Biophys. Res. Commun., 230: 196-201, 1997.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.230
, pp. 196-201
-
-
Pirollo, K.F.1
Hao, Z.2
Rait, A.3
Ho, C.W.4
Chang, E.H.5
-
2
-
-
0035890610
-
2 checkpoint abrogator
-
2 checkpoint abrogator. Cancer Res., 61: 8211-8217, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 8211-8217
-
-
Wang, Y.1
Li, J.2
Booller, R.N.3
Kraker, A.4
Lawrence, T.5
Leopold, W.R.6
Sun, Y.7
-
3
-
-
0037089516
-
Inhibition of radiation-induced nuclear factor-κB activation by an anti-Ras single-chain antibody fragment: Lack of involvement in radiosensitization
-
Russell, J. S., Raju, U., Gumin, G. J., Lang, F. F., Wilson, D. R., Huet, T., and Tofilon, P. J. Inhibition of radiation-induced nuclear factor-κB activation by an anti-Ras single-chain antibody fragment: lack of involvement in radiosensitization. Cancer Res., 62: 2318-2326, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 2318-2326
-
-
Russell, J.S.1
Raju, U.2
Gumin, G.J.3
Lang, F.F.4
Wilson, D.R.5
Huet, T.6
Tofilon, P.J.7
-
4
-
-
0036261727
-
2/M phase, and protection from apoptosis
-
2/M phase, and protection from apoptosis. Mol. Cell. Biol., 22: 4189-4201, 2002.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4189-4201
-
-
Slupianek, A.1
Hoser, G.2
Majsterek, I.3
Bronisz, A.4
Malecki, M.5
Blasiak, J.6
Fishel, R.7
Skorski, T.8
-
5
-
-
0036219609
-
Hsp90 inhibitors as novel cancer chemotherapeutic agents
-
Neckers, L. Hsp90 inhibitors as novel cancer chemotherapeutic agents. Trends Mol. Med., 8: S55-S61, 2002.
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Neckers, L.1
-
6
-
-
0035872443
-
The Ras radiation resistance pathway
-
Gupta, A. K., Bakanauskas, V. J., Cerniglia, G. J., Cheng, Y., Bernhard, E. J., Muschel, R. J., and McKenna, W. G. The Ras radiation resistance pathway. Cancer Res., 61: 4278-4282, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 4278-4282
-
-
Gupta, A.K.1
Bakanauskas, V.J.2
Cerniglia, G.J.3
Cheng, Y.4
Bernhard, E.J.5
Muschel, R.J.6
McKenna, W.G.7
-
7
-
-
0033559619
-
Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene
-
Pietras, R. J., Poen, J. C., Gallardo, D., Wongvipat, P. N., Lee, H. J., and Slamon, D. J. Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene. Cancer Res., 59: 1347-1355, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 1347-1355
-
-
Pietras, R.J.1
Poen, J.C.2
Gallardo, D.3
Wongvipat, P.N.4
Lee, H.J.5
Slamon, D.J.6
-
8
-
-
0036091221
-
Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: A novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts
-
Neckers, L. Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: a novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res., 8: 986-993, 2002. Clin. Cancer Res., 8: 962-966, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 986-993
-
-
Neckers, L.1
-
9
-
-
0036098002
-
-
Neckers, L. Heat shock protein 90 inhibition by 17-allylamino-17-demethoxy-eldanamycin: a novel therapeutic approach for treating hormone-refractory prostate cancer. Commentary re: D. B. Solit et al., 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and Her-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res., 8: 986-993, 2002. Clin. Cancer Res., 8: 962-966, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 962-966
-
-
-
10
-
-
0021244486
-
Mean inactivation dose: A useful concept for intercomparison of human cell survival curves
-
Fertil, B., Dertinger, H., Courdi, A., and Malaise, E. P. Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat. Res., 99: 73-84, 1984.
-
(1984)
Radiat. Res.
, vol.99
, pp. 73-84
-
-
Fertil, B.1
Dertinger, H.2
Courdi, A.3
Malaise, E.P.4
-
11
-
-
0030996827
-
Discrimination of late apoptotic/necrotic cells (type III) by flow cytometry in solid tumors
-
O'Brien, M. C., Healy, S. F., Raney, S. R., Hurst, J. M., Avner, B., Hanly, A., Mies, C., Freeman, J. W., Snow, C., Koester, S. K., and Bolton, W. E. Discrimination of late apoptotic/necrotic cells (type III) by flow cytometry in solid tumors. Cytometry, 28: 81-89, 1997.
-
(1997)
Cytometry
, vol.28
, pp. 81-89
-
-
O'Brien, M.C.1
Healy, S.F.2
Raney, S.R.3
Hurst, J.M.4
Avner, B.5
Hanly, A.6
Mies, C.7
Freeman, J.W.8
Snow, C.9
Koester, S.K.10
Bolton, W.E.11
-
12
-
-
0035872396
-
Disruption of the EF-2 kinase/Hsp90 protein complex: A possible mechanism to inhibit glioblastoma by geldanamycin
-
Yang, J., Yang, J. M., Iannone, M., Shih, W. J., Lin, Y., and Hait, W. N. Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin. Cancer Res., 61: 4010-4016, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 4010-4016
-
-
Yang, J.1
Yang, J.M.2
Iannone, M.3
Shih, W.J.4
Lin, Y.5
Hait, W.N.6
-
13
-
-
0031875042
-
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
-
Schulte, T. W., and Neckers, L. M. The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin. Cancer Chemother. Pharmacol., 42: 273-279, 1998.
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, pp. 273-279
-
-
Schulte, T.W.1
Neckers, L.M.2
-
14
-
-
0035872442
-
Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis
-
Hostein, I., Robertson, D., DiStefano, F., Workman, P., and Clarke, P. A. Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. Cancer Res., 61: 4003-4009, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 4003-4009
-
-
Hostein, I.1
Robertson, D.2
DiStefano, F.3
Workman, P.4
Clarke, P.A.5
-
15
-
-
0034886833
-
Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: Sequence and tumor biology matters
-
Munster, P. N., Basso, A., Solit, D., Norton, L., and Rosen, N. Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. Clin. Cancer Res., 7: 2228-2236, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2155-2158
-
-
Munster, P.N.1
Basso, A.2
Solit, D.3
Norton, L.4
Rosen, N.5
-
16
-
-
0034890377
-
-
Munster, P. N., Basso, A., Solit, D., Norton, L., and Rosen, N. Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See The Biology Behind: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001. Clin. Cancer Res., 7: 2228-2236, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2228-2236
-
-
-
17
-
-
0036091221
-
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts
-
Solit, D. B., Zheng, F. F., Drobnjak, M., Munster, P. N., Higgins, B., Verbel, D., Heller, G., Tong, W., Cordon-Cardo, C., Agus, D. B., Scher, H. I., and Rosen, N. 17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts. Clin. Cancer Res., 8: 986-993, 2002.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 986-993
-
-
Solit, D.B.1
Zheng, F.F.2
Drobnjak, M.3
Munster, P.N.4
Higgins, B.5
Verbel, D.6
Heller, G.7
Tong, W.8
Cordon-Cardo, C.9
Agus, D.B.10
Scher, H.I.11
Rosen, N.12
-
19
-
-
0036606332
-
Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway
-
Munster, P. N., Marchion, D. C., Basso, A. D., and Rosen, N. Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3′-kinase-AKT-dependent pathway. Cancer Res., 62: 3132-3137, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 3132-3137
-
-
Munster, P.N.1
Marchion, D.C.2
Basso, A.D.3
Rosen, N.4
-
20
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
O'Connor, P. M., Jackman, J., Bae, I., Myers, T. G., Fan, S., Mutoh, M., Scudiero, D. A., Monks, A., Sausville, E. A., Weinstein, J. N., Friend, S., Fornace, A. J., Jr., and Kohn, K. W. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res., 57: 4285-4300, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
Myers, T.G.4
Fan, S.5
Mutoh, M.6
Scudiero, D.A.7
Monks, A.8
Sausville, E.A.9
Weinstein, J.N.10
Friend, S.11
Fornace A.J., Jr.12
Kohn, K.W.13
-
21
-
-
0034800172
-
Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after γ-irradiation
-
Tezuka, M., Watanabe, H., Nakamura, S., Yu, D., Aung, W., Sasaki, T., Shibuya, H., and Miura, M. Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after γ-irradiation. Clin. Cancer Res., 7: 3206-3214, 2001.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3206-3214
-
-
Tezuka, M.1
Watanabe, H.2
Nakamura, S.3
Yu, D.4
Aung, W.5
Sasaki, T.6
Shibuya, H.7
Miura, M.8
-
22
-
-
0036568414
-
Independent prognostic significance of HER-2 oncoprotein expression in pNO prostate cancer undergoing curative radiotherapy
-
Fossa, A., Lilleby, W., Fossa, S. D. Gaudemack G., Torlakovic, G., and Berner, A. Independent prognostic significance of HER-2 oncoprotein expression in pNO prostate cancer undergoing curative radiotherapy. Int. J. Cancer, 99: 100-105, 2002.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 100-105
-
-
Fossa, A.1
Lilleby, W.2
Fossa, S.D.3
Gaudemack, G.4
Torlakovic, G.5
Berner, A.6
-
23
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Wash. DC), 235: 177-182, 1987.
-
(1987)
Science (Wash. DC)
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
24
-
-
0032189381
-
Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
-
Coffer, P. J., Jin, J., and Woodgett, J. R. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J., 335: 1-13, 1998.
-
(1998)
Biochem. J.
, vol.335
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
25
-
-
0024363796
-
Radioresistance induced by oncogenic transformation
-
Ling, C. C., and Endlich, B. Radioresistance induced by oncogenic transformation. Radiat. Res., 120: 267-279, 1989.
-
(1989)
Radiat. Res.
, vol.120
, pp. 267-279
-
-
Ling, C.C.1
Endlich, B.2
|