-
1
-
-
0642317080
-
Regulation of the eukaryotic cell cycle
-
McGowan, C. H. 2003 Regulation of the eukaryotic cell cycle. Prog. Cell Cycle Res. 5, 1-4.
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 1-4
-
-
McGowan, C.H.1
-
2
-
-
0035902180
-
Oncogenic kinase signalling
-
doi:10.1038/ 35077225
-
Blume-Jensen, P. & Hunter, T. 2001 Oncogenic kinase signalling. Nature 411, 355-365. (doi:10.1038/ 35077225)
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
3
-
-
20444383859
-
Protein phosphorylation in signaling: 50 years and counting
-
doi:10.1016/j.tibs.2005.04.013
-
Pawson, T. & Scott, J. D. 2005 Protein phosphorylation in signaling: 50 years and counting. Trends Biochem. Sci. 30, 286-290. (doi:10.1016/j.tibs.2005.04.013)
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 286-290
-
-
Pawson, T.1
Scott, J.D.2
-
4
-
-
0036769119
-
Regulation and targets of receptor tyrosine kinases
-
doi:10.1016/S0959-8049(02)80597-4
-
Pawson, T. 2002 Regulation and targets of receptor tyrosine kinases. Eur. J. Cancer 38(Suppl. 5), S3-S10. (doi:10.1016/S0959-8049(02)80597-4)
-
(2002)
Eur. J. Cancer
, vol.38
, Issue.SUPPL. 5
-
-
Pawson, T.1
-
5
-
-
0037013143
-
The conformational plasticity of protein kinases
-
doi:10. 1016/S0092-8674(02)00741-9
-
Huse, M. & Kuriyan, J. 2002 The conformational plasticity of protein kinases. Cell 109, 275-282. (doi:10. 1016/S0092-8674(02)00741-9)
-
(2002)
Cell
, vol.109
, pp. 275-282
-
-
Huse, M.1
Kuriyan, J.2
-
6
-
-
0035413608
-
Dynamics of cAMP-dependent protein kinase
-
doi:10.1021/cr000226k
-
Johnson, D. A., Akamine, P., Radzio-Andzelm, E., Madhusudan, M. & Taylor, S. S. 2001 Dynamics of cAMP-dependent protein kinase. Chem. Rev. 101, 2243-2270. (doi:10.1021/cr000226k)
-
(2001)
Chem. Rev.
, vol.101
, pp. 2243-2270
-
-
Johnson, D.A.1
Akamine, P.2
Radzio-Andzelm, E.3
Madhusudan, M.4
Taylor, S.S.5
-
7
-
-
0029993727
-
Active and inactive protein kinases: Structural basis for regulation
-
doi:10.1016/S0092-8674 (00)81092-2
-
Johnson, L. N., Noble, M. E. & Owen, D. J. 1996 Active and inactive protein kinases: structural basis for regulation. Cell 85, 149-158. (doi:10.1016/S0092-8674 (00)81092-2)
-
(1996)
Cell
, vol.85
, pp. 149-158
-
-
Johnson, L.N.1
Noble, M.E.2
Owen, D.J.3
-
8
-
-
0028568989
-
Domain movements in protein kinases
-
doi:10.1016/0959-440X(94) 90272-0
-
Cox, S., Radzio-Andzelm, E. & Taylor, S. S. 1994 Domain movements in protein kinases. Curr. Opin. Struct. Biol. 4, 893-901. (doi:10.1016/0959-440X(94) 90272-0)
-
(1994)
Curr. Opin. Struct. Biol.
, vol.4
, pp. 893-901
-
-
Cox, S.1
Radzio-Andzelm, E.2
Taylor, S.S.3
-
9
-
-
1542269006
-
PKA: A portrait of protein kinase dynamics
-
Taylor, S. S., Yang, J., Wu, J., Haste, N. M., Radzio-Andzelm, E. & Anand, G. 2004 PKA: a portrait of protein kinase dynamics. Biochim. Biophys. Acta 1697, 259-269.
-
(2004)
Biochim. Biophys. Acta
, vol.1697
, pp. 259-269
-
-
Taylor, S.S.1
Yang, J.2
Wu, J.3
Haste, N.M.4
Radzio-Andzelm, E.5
Anand, G.6
-
10
-
-
79551594605
-
Protein kinases: Evolution of dynamic regulatory proteins
-
doi:10.1016/j.tibs.2010.09.006
-
Taylor, S. S. & Kornev, A. P. 2010 Protein kinases: evolution of dynamic regulatory proteins. Trends Biochem. Sci. 36, 65-77. (doi:10.1016/j.tibs.2010.09.006)
-
(2010)
Trends Biochem. Sci.
, vol.36
, pp. 65-77
-
-
Taylor, S.S.1
Kornev, A.P.2
-
11
-
-
33847061197
-
Networks for the allosteric control of protein kinases
-
doi:10.1016/j.sbi.2006.10.011
-
Shi, Z., Resing, K. A. & Ahn, N.G. 2006 Networks for the allosteric control of protein kinases. Curr. Opin. Struct. Biol. 16, 686-692. (doi:10.1016/j.sbi.2006.10.011)
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 686-692
-
-
Shi, Z.1
Resing, K.A.2
Ahn, N.G.3
-
12
-
-
0029767016
-
Structural basis of cyclin-dependent kinase activation by phosphorylation
-
doi:10.1038/nsb0896-696
-
Russo, A. A., Jeffrey, P. D. & Pavletich, N. P. 1996 Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat. Struct. Biol. 3, 696-700. (doi:10.1038/nsb0896-696)
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 696-700
-
-
Russo, A.A.1
Jeffrey, P.D.2
Pavletich, N.P.3
-
13
-
-
0028931265
-
Principles of CDK regulation
-
doi:10.1038/374131a0
-
Morgan, D. O. 1995 Principles of CDK regulation. Nature 374, 131-134. (doi:10.1038/374131a0)
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
14
-
-
0033574614
-
Mechanisms of cyclin-dependent kinase regulation: Structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
-
doi:10.1006/jmbi.1999.2640
-
Pavletich, N. P. 1999 Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J. Mol. Biol. 287, 821-828. (doi:10.1006/jmbi.1999.2640)
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 821-828
-
-
Pavletich, N.P.1
-
15
-
-
4444353636
-
Regulation of protein kinases; controlling activity through activation segment conformation
-
doi:10. 1016/j.molcel.2004.08.024
-
Nolen, B., Taylor, S. & Ghosh, G. 2004 Regulation of protein kinases; controlling activity through activation segment conformation. Mol. Cell 15, 661-675. (doi:10. 1016/j.molcel.2004.08.024)
-
(2004)
Mol. Cell
, vol.15
, pp. 661-675
-
-
Nolen, B.1
Taylor, S.2
Ghosh, G.3
-
16
-
-
0030830868
-
Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases
-
doi:10.1016/S0092-8674(00)80274-3
-
Hon, W. C., McKay, G. A., Thompson, P. R., Sweet, R. M., Yang, D. S., Wright, G. D. & Berghuis, A. M. 1997 Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases. Cell 89, 887-895. (doi:10.1016/S0092-8674(00)80274-3)
-
(1997)
Cell
, vol.89
, pp. 887-895
-
-
Hon, W.C.1
McKay, G.A.2
Thompson, P.R.3
Sweet, R.M.4
Yang, D.S.5
Wright, G.D.6
Berghuis, A.M.7
-
17
-
-
0036100787
-
Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases
-
doi:10. 1110/ps.3560102
-
Krupa, A. & Srinivasan, N. 2002 Lipopolysaccharide phosphorylating enzymes encoded in the genomes of Gram-negative bacteria are related to the eukaryotic protein kinases. Protein Sci. 11, 1580-1584. (doi:10. 1110/ps.3560102)
-
(2002)
Protein Sci.
, vol.11
, pp. 1580-1584
-
-
Krupa, A.1
Srinivasan, N.2
-
18
-
-
0142039652
-
The crystal structure of choline kinase reveals a eukaryotic protein kinase fold
-
Peisach, D., Gee, P., Kent, C. & Xu, Z. 2003 The crystal structure of choline kinase reveals a eukaryotic protein kinase fold. Structure (Camb). 11, 703-713.
-
(2003)
Structure (Camb)
, vol.11
, pp. 703-713
-
-
Peisach, D.1
Gee, P.2
Kent, C.3
Xu, Z.4
-
19
-
-
33947226782
-
Structural and functional diversity of the microbial kinome
-
doi:10. 1371/journal.pbio.0050017
-
Kannan, N., Taylor, S. S., Zhai, Y., Venter, J. C. & Manning, G. 2007 Structural and functional diversity of the microbial kinome. PLoS Biol. 5, e17. (doi:10. 1371/journal.pbio.0050017)
-
(2007)
PLoS Biol.
, vol.5
-
-
Kannan, N.1
Taylor, S.S.2
Zhai, Y.3
Venter, J.C.4
Manning, G.5
-
20
-
-
77951216666
-
Genomics, evolution, and crystal structure of a new family of bacterial spore kinases
-
doi:10.1002/prot.22663
-
Scheeff, E. D., Axelrod, H. L., Miller, M. D., Chiu, H. J., Deacon, A. M., Wilson, I. A. & Manning, G. 2010 Genomics, evolution, and crystal structure of a new family of bacterial spore kinases. Proteins 78, 1470-1482. (doi:10.1002/prot.22663)
-
(2010)
Proteins
, vol.78
, pp. 1470-1482
-
-
Scheeff, E.D.1
Axelrod, H.L.2
Miller, M.D.3
Chiu, H.J.4
Deacon, A.M.5
Wilson, I.A.6
Manning, G.7
-
21
-
-
0031722706
-
Novel families of putative protein kinases in bacteria and archaea: Evolution of the 'eukaryotic' protein kinase superfamily
-
Leonard, C. J., Aravind, L. & Koonin, E. V. 1998 Novel families of putative protein kinases in bacteria and archaea: evolution of the 'eukaryotic' protein kinase superfamily. Genome Res. 8, 1038-1047.
-
(1998)
Genome Res.
, vol.8
, pp. 1038-1047
-
-
Leonard, C.J.1
Aravind, L.2
Koonin, E.V.3
-
22
-
-
0032774575
-
Aminoglycoside antibiotic phosphotransferases are also serine protein kinases
-
doi:10.1016/S1074-5521(99)80016-7
-
Daigle, D. M., McKay, G. A., Thompson, P. R. & Wright, G. D. 1999 Aminoglycoside antibiotic phosphotransferases are also serine protein kinases. Chem. Biol. 6, 11-18. (doi:10.1016/S1074-5521(99)80016-7)
-
(1999)
Chem. Biol.
, vol.6
, pp. 11-18
-
-
Daigle, D.M.1
McKay, G.A.2
Thompson, P.R.3
Wright, G.D.4
-
23
-
-
0035979336
-
Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase
-
doi:10.1021/bi010504p
-
Burk, D. L., Hon, W. C., Leung, A. K. & Berghuis, A. M. 2001 Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase. Biochemistry 40, 8756-8764. (doi:10.1021/bi010504p)
-
(2001)
Biochemistry
, vol.40
, pp. 8756-8764
-
-
Burk, D.L.1
Hon, W.C.2
Leung, A.K.3
Berghuis, A.M.4
-
24
-
-
23444440823
-
Inactivation of antibiotics and the dissemination of resistance genes
-
doi:10.1126/science.8153624
-
Davies, J. 1994 Inactivation of antibiotics and the dissemination of resistance genes. Science 264, 375-382. (doi:10.1126/science.8153624)
-
(1994)
Science
, vol.264
, pp. 375-382
-
-
Davies, J.1
-
25
-
-
41849110846
-
Structural evolution of the protein kinase-like superfamily
-
doi:10.1371/journal.pcbi.0010049
-
Scheeff, E. D. & Bourne, P. E. 2005 Structural evolution of the protein kinase-like superfamily. PLoS Comput. Biol. 1, e49. (doi:10.1371/journal.pcbi.0010049)
-
(2005)
PLoS Comput. Biol.
, vol.1
-
-
Scheeff, E.D.1
Bourne, P.E.2
-
26
-
-
0033152604
-
The crystal structure of the Physarum polycephalum actin-fragmin kinase: An atypical protein kinase with a specialized substrate-binding domain
-
doi:10.1093/emboj/18.11. 2923
-
Steinbacher, S., Hof, P., Eichinger, L., Schleicher, M., Gettemans, J., Vandekerckhove, J., Huber, R. & Benz, J. 1999 The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain. Embo J. 18, 2923-2929. (doi:10.1093/emboj/18.11. 2923)
-
(1999)
Embo J.
, vol.18
, pp. 2923-2929
-
-
Steinbacher, S.1
Hof, P.2
Eichinger, L.3
Schleicher, M.4
Gettemans, J.5
Vandekerckhove, J.6
Huber, R.7
Benz, J.8
-
27
-
-
0033634827
-
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
-
doi:10.1016/S1097-2765(05)00089-4
-
Walker, E. H., Pacold, M. E., Perisic, O., Stephens, L., Hawkins, P. T., Wymann, M. P. & Williams, R. L. 2000 Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol. Cell 6, 909-919. (doi:10.1016/S1097-2765(05)00089-4)
-
(2000)
Mol. Cell
, vol.6
, pp. 909-919
-
-
Walker, E.H.1
Pacold, M.E.2
Perisic, O.3
Stephens, L.4
Hawkins, P.T.5
Wymann, M.P.6
Williams, R.L.7
-
28
-
-
77953720173
-
Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase
-
doi:10.1038/nature09088
-
Zheng, J. & Jia, Z. 2010 Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase. Nature 465, 961-965. (doi:10.1038/nature09088)
-
(2010)
Nature
, vol.465
, pp. 961-965
-
-
Zheng, J.1
Jia, Z.2
-
29
-
-
80053002310
-
Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/ phosphatase
-
doi:10. 1021/bi200809p
-
Yates, S. P., Edwards, T. E., Bryan, C. M., Stein, A. J., Van Voorhis, W. C., Myler, P. J., Stewart, L. J., Zheng, J. & Jia, Z. 2011 Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/ phosphatase. Biochemistry 50, 8103-8106. (doi:10. 1021/bi200809p)
-
(2011)
Biochemistry
, vol.50
, pp. 8103-8106
-
-
Yates, S.P.1
Edwards, T.E.2
Bryan, C.M.3
Stein, A.J.4
van Voorhis, W.C.5
Myler, P.J.6
Stewart, L.J.7
Zheng, J.8
Jia, Z.9
-
30
-
-
34250878954
-
Mechanisms of specificity in protein phosphorylation
-
doi:10.1038/nrm2203
-
Ubersax, J. A. & Ferrell Jr, J. E. 2007 Mechanisms of specificity in protein phosphorylation. Nat. Rev. Mol. Cell Biol. 8, 530-541. (doi:10.1038/nrm2203)
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 530-541
-
-
Ubersax, J.A.1
Ferrell Jr., J.E.2
-
31
-
-
79960255057
-
Crystal structures of antibiotic-bound complexes of aminoglycoside 2"-phosphotransferase IVa highlight the diversity in substrate binding modes among aminoglycoside kinases
-
doi:10.1021/ bi200747f
-
Shi, K., Houston, D. R. & Berghuis, A. M. 2011 Crystal structures of antibiotic-bound complexes of aminoglycoside 2"-phosphotransferase IVa highlight the diversity in substrate binding modes among aminoglycoside kinases. Biochemistry 50, 6237-6244. (doi:10.1021/ bi200747f)
-
(2011)
Biochemistry
, vol.50
, pp. 6237-6244
-
-
Shi, K.1
Houston, D.R.2
Berghuis, A.M.3
-
32
-
-
0037032835
-
The protein kinase complement of the human genome
-
doi:10. 1126/science.1075762
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T. & Sudarsanam, S. 2002 The protein kinase complement of the human genome. Science 298, 1912-1934. (doi:10. 1126/science.1075762)
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
33
-
-
23644452511
-
Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?
-
doi:10.1016/j.jmb.2005.06.057
-
Kannan, N. & Neuwald, A. F. 2005 Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component? J. Mol. Biol. 351, 956-972. (doi:10.1016/j.jmb.2005.06.057)
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 956-972
-
-
Kannan, N.1
Neuwald, A.F.2
-
34
-
-
0029020282
-
Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
-
Hanks, S. K. & Hunter, T. 1995 Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. Faseb J. 9, 576-596.
-
(1995)
Faseb J.
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
35
-
-
0033224309
-
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
-
doi:10.1038/15674
-
Brown, N. R., Noble, M. E., Endicott, J. A. & Johnson, L. N. 1999 The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat. Cell Biol. 1, 438-443. (doi:10.1038/15674)
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 438-443
-
-
Brown, N.R.1
Noble, M.E.2
Endicott, J.A.3
Johnson, L.N.4
-
36
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
doi:10.1126/science.1862342
-
Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S. & Sowadski, J. 1991 Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253, 407-414. (doi:10.1126/science.1862342)
-
(1991)
Science
, vol.253
, pp. 407-414
-
-
Knighton, D.R.1
Zheng, J.H.2
Ten Eyck, L.F.3
Ashford, V.A.4
Xuong, N.H.5
Taylor, S.S.6
Sowadski, J.7
-
37
-
-
33745002702
-
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
-
doi:10.1016/j.cell.2006.05.013
-
Zhang, X., Gureasko, J., Shen, K., Cole, P. A. & Kuriyan, J. 2006 An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 125, 1137-1149. (doi:10.1016/j.cell.2006.05.013)
-
(2006)
Cell
, vol.125
, pp. 1137-1149
-
-
Zhang, X.1
Gureasko, J.2
Shen, K.3
Cole, P.A.4
Kuriyan, J.5
-
38
-
-
0034476899
-
Structure and mechanism of homoserine kinase: Prototype for the GHMP kinase superfamily
-
doi:10.1016/ S0969-2126(00)00533-5
-
Zhou, T., Daugherty, M., Grishin, N. V., Osterman, A. L. & Zhang, H. 2000 Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily. Structure 8, 1247-1257. (doi:10.1016/ S0969-2126(00)00533-5)
-
(2000)
Structure
, vol.8
, pp. 1247-1257
-
-
Zhou, T.1
Daugherty, M.2
Grishin, N.V.3
Osterman, A.L.4
Zhang, H.5
-
39
-
-
22544465251
-
Structure and activity of the atypical serine kinase Rio1
-
doi:10. 1111/j.1742-4658.2005.04796.x
-
Laronde-Leblanc, N., Guszczynski, T., Copeland, T. & Wlodawer, A. 2005 Structure and activity of the atypical serine kinase Rio1. Febs J. 272, 3698-3713. (doi:10. 1111/j.1742-4658.2005.04796.x)
-
(2005)
Febs J.
, vol.272
, pp. 3698-3713
-
-
Laronde-Leblanc, N.1
Guszczynski, T.2
Copeland, T.3
Wlodawer, A.4
-
40
-
-
0035947077
-
Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity
-
doi:10.1016/S1097-2765(01)00256-8
-
Yamaguchi, H., Matsushita, M., Nairn, A. C. & Kuriyan, J. 2001 Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol. Cell 7, 1047-1057. (doi:10.1016/S1097-2765(01)00256-8)
-
(2001)
Mol. Cell
, vol.7
, pp. 1047-1057
-
-
Yamaguchi, H.1
Matsushita, M.2
Nairn, A.C.3
Kuriyan, J.4
-
41
-
-
0027457571
-
A template for the protein kinase family
-
doi:10.1016/0968-0004(93)80001-R
-
Taylor, S. S., Knighton, D. R., Zheng, J., Sowadski, J. M., Gibbs, C. S. & Zoller, M. J. 1993 A template for the protein kinase family. Trends Biochem. Sci. 18, 84-89. (doi:10.1016/0968-0004(93)80001-R)
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 84-89
-
-
Taylor, S.S.1
Knighton, D.R.2
Zheng, J.3
Sowadski, J.M.4
Gibbs, C.S.5
Zoller, M.J.6
-
42
-
-
0028773477
-
Three protein kinase structures define a common motif
-
doi:10.1016/S0969-2126(00)00036-8
-
Taylor, S. S. & Radzio-Andzelm, E. 1994 Three protein kinase structures define a common motif. Structure 2, 345-355. (doi:10.1016/S0969-2126(00)00036-8)
-
(1994)
Structure
, vol.2
, pp. 345-355
-
-
Taylor, S.S.1
Radzio-Andzelm, E.2
-
43
-
-
80052256972
-
Molecular basis of actin nucleation factor cooperativity: Crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND)*-formin-2 formin SPIR interaction motif (FSI) complex
-
doi:10.1074/jbc. M111.257782
-
Zeth, K., Pechlivanis, M., Samol, A., Pleiser, S., Vonrhein, C. & Kerkhoff, E. 2011 Molecular basis of actin nucleation factor cooperativity: crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND)*-formin-2 formin SPIR interaction motif (FSI) complex. J. Biol. Chem. 286, 30 732-30 739. (doi:10.1074/jbc. M111.257782)
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30732-30739
-
-
Zeth, K.1
Pechlivanis, M.2
Samol, A.3
Pleiser, S.4
Vonrhein, C.5
Kerkhoff, E.6
-
44
-
-
0038825338
-
The KIND module: A putative signalling domain evolved from the C-lobe of the protein kinase fold
-
doi:10.1016/S0968-0004(03) 00116-6
-
Ciccarelli, F. D., Bork, P. & Kerkhoff, E. 2003 The KIND module: a putative signalling domain evolved from the C-lobe of the protein kinase fold. Trends Biochem. Sci. 28, 349-352. (doi:10.1016/S0968-0004(03) 00116-6)
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 349-352
-
-
Ciccarelli, F.D.1
Bork, P.2
Kerkhoff, E.3
-
45
-
-
35948999631
-
Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2
-
doi:10.1083/jcb.200702036
-
Huang, J., Furuya, A. & Furuichi, T. 2007 Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2. J. Cell Biol. 179, 539-552. (doi:10.1083/jcb.200702036)
-
(2007)
J. Cell Biol.
, vol.179
, pp. 539-552
-
-
Huang, J.1
Furuya, A.2
Furuichi, T.3
-
46
-
-
79961081154
-
Structure and function of the interacting domains of Spire and Fmn-family formins
-
doi:10.1073/pnas.1105703108
-
Vizcarra, C. L., Kreutz, B., Rodal, A. A., Toms, A. V., Lu, J., Zheng, W., Quinlan, M. E. & Eck, M. J. 2011 Structure and function of the interacting domains of Spire and Fmn-family formins. Proc. Natl Acad. Sci. USA 108, 11 884-11 889. (doi:10.1073/pnas.1105703108)
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 11884-11889
-
-
Vizcarra, C.L.1
Kreutz, B.2
Rodal, A.A.3
Toms, A.V.4
Lu, J.5
Zheng, W.6
Quinlan, M.E.7
Eck, M.J.8
-
47
-
-
79955529278
-
Mitogenactivated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38a
-
doi:10.1074/jbc.M110. 203786
-
Zhang, Y. Y., Wu, J. W. & Wang, Z. X. 2011 Mitogenactivated protein kinase (MAPK) phosphatase 3-mediated cross-talk between MAPKs ERK2 and p38a. J. Biol. Chem. 286, 16150-16162. (doi:10.1074/jbc.M110. 203786)
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16150-16162
-
-
Zhang, Y.Y.1
Wu, J.W.2
Wang, Z.X.3
-
48
-
-
77951689893
-
Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases
-
doi:10.1021/bi100070r
-
Namboodiri, H. V., Bukhtiyarova, M., Ramcharan, J., Karpusas, M., Lee, Y. & Springman, E. B. 2010 Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry 49, 3611-3618. (doi:10.1021/bi100070r)
-
(2010)
Biochemistry
, vol.49
, pp. 3611-3618
-
-
Namboodiri, H.V.1
Bukhtiyarova, M.2
Ramcharan, J.3
Karpusas, M.4
Lee, Y.5
Springman, E.B.6
-
49
-
-
33845197964
-
Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism
-
doi:10.1073/pnas.0607656103
-
Kornev, A. P., Haste, N. M., Taylor, S. S. & Eyck, L. F. 2006 Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism. Proc. Natl Acad. Sci. USA 103, 17 783-17 788. (doi:10.1073/pnas.0607656103)
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17783-17788
-
-
Kornev, A.P.1
Haste, N.M.2
Taylor, S.S.3
Eyck, L.F.4
-
50
-
-
55749102720
-
A helix scaffold for the assembly of active protein kinases
-
doi:10. 1073/pnas.0807988105
-
Kornev, A. P., Taylor, S. S. & Ten Eyck, L. F. 2008 A helix scaffold for the assembly of active protein kinases. Proc. Natl Acad. Sci. USA 105, 14 377-14 382. (doi:10. 1073/pnas.0807988105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 14377-14382
-
-
Kornev, A.P.1
Taylor, S.S.2
Ten Eyck, L.F.3
-
51
-
-
53549104402
-
Activation of tyrosine kinases by mutation of the gatekeeper threonine
-
doi:10.1038/nsmb.1486
-
Azam, M., Seeliger, M. A., Gray, N. S., Kuriyan, J. & Daley, G. Q. 2008 Activation of tyrosine kinases by mutation of the gatekeeper threonine. Nat. Struct. Mol. Biol. 15, 1109-1118. (doi:10.1038/nsmb.1486)
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 1109-1118
-
-
Azam, M.1
Seeliger, M.A.2
Gray, N.S.3
Kuriyan, J.4
Daley, G.Q.5
-
52
-
-
78651361760
-
Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue
-
doi:10.1021/bi101379m
-
Joseph, R. E. & Andreotti, A. H. 2010 Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue. Biochemistry 50, 221-229. (doi:10.1021/bi101379m)
-
(2010)
Biochemistry
, vol.50
, pp. 221-229
-
-
Joseph, R.E.1
Andreotti, A.H.2
-
53
-
-
58549114067
-
A conserved protonation-dependent switch controls drug binding in the Abl kinase
-
doi:10.1073/pnas.0811223106
-
Shan, Y., Seeliger, M. A., Eastwood, M. P., Frank, F., Xu, H., Jensen, M. O., Dror, R. O., Kuriyan, J. & Shaw, D. E. 2009 A conserved protonation-dependent switch controls drug binding in the Abl kinase. Proc. Natl Acad. Sci. USA 106, 139-144. (doi:10.1073/pnas.0811223106)
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 139-144
-
-
Shan, Y.1
Seeliger, M.A.2
Eastwood, M.P.3
Frank, F.4
Xu, H.5
Jensen, M.O.6
Dror, R.O.7
Kuriyan, J.8
Shaw, D.E.9
-
54
-
-
33646755174
-
A Src-like inactive conformation in the abl tyrosine kinase domain
-
doi:10.1371/journal.pbio.0040144
-
Levinson, N. M., Kuchment, O., Shen, K., Young, M. A., Koldobskiy, M., Karplus, M., Cole, P. A. & Kuriyan, J. 2006 A Src-like inactive conformation in the abl tyrosine kinase domain. PLoS Biol. 4, e144. (doi:10.1371/journal.pbio.0040144)
-
(2006)
PLoS Biol.
, vol.4
-
-
Levinson, N.M.1
Kuchment, O.2
Shen, K.3
Young, M.A.4
Koldobskiy, M.5
Karplus, M.6
Cole, P.A.7
Kuriyan, J.8
-
55
-
-
32044462537
-
NMR characterization of kinase p38 dynamics in free and ligand-bound forms
-
doi:10.1002/anie. 200502770
-
Vogtherr, M. et al. 2006 NMR characterization of kinase p38 dynamics in free and ligand-bound forms. Angew. Chem. Int. Ed. Engl. 45, 993-997. (doi:10.1002/anie. 200502770)
-
(2006)
Angew. Chem. Int. Ed. Engl.
, vol.45
, pp. 993-997
-
-
Vogtherr, M.1
-
56
-
-
0037436388
-
Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure
-
doi:10. 1016/S0022-2836(02)01446-8
-
Akamine, P., Madhusudan, Wu, J., Xuong, N. H., Ten Eyck, L. F. & Taylor, S. S. 2003 Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure. J. Mol. Biol. 327, 159-171. (doi:10. 1016/S0022-2836(02)01446-8)
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 159-171
-
-
Akamine, P.1
Madhusudan, W.J.2
Xuong, N.H.3
Ten Eyck, L.F.4
Taylor, S.S.5
-
57
-
-
20044379405
-
Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase
-
doi:10.1074/jbc.M409123200
-
Qian, K. C. et al. 2005 Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase. J. Biol. Chem. 280, 6130-6137. (doi:10.1074/jbc.M409123200)
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6130-6137
-
-
Qian, K.C.1
-
58
-
-
34548250374
-
A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases
-
doi:10.1016/j.molcel.2007.06.028
-
Chen, H., Ma, J., Li, W., Eliseenkova, A. V., Xu, C., Neubert, T. A., Miller, W. Â. T. & Mohammadi, M. 2007 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol. Cell. 27, 717-730. (doi:10.1016/j.molcel.2007.06.028)
-
(2007)
Mol. Cell.
, vol.27
, pp. 717-730
-
-
Chen, H.1
Ma, J.2
Li, W.3
Eliseenkova, A.V.4
Xu, C.5
Neubert, T.A.6
Miller, W.A.T.7
Mohammadi, M.8
-
59
-
-
0026640184
-
Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit
-
Gibbs, C. S., Knighton, D. R., Sowadski, J. M., Taylor, S. S. & Zoller, M. J. 1992 Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit. J. Biol. Chem. 267, 4806-4814.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 4806-4814
-
-
Gibbs, C.S.1
Knighton, D.R.2
Sowadski, J.M.3
Taylor, S.S.4
Zoller, M.J.5
-
60
-
-
84856232223
-
A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryote protein kinase fold
-
doi:10.1016/j. jmb.2011.11.035
-
Yang, J., Wu, J., Steichen, J. M., Kornev, A. P., Deal, M. S., Li, S., Sankaran, B., Woods Jr, V. L. & Taylor, S. S. 2011 A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryote protein kinase fold. J. Mol. Biol. 415, 666-679. (doi:10.1016/j. jmb.2011.11.035)
-
(2011)
J. Mol. Biol.
, vol.415
, pp. 666-679
-
-
Yang, J.1
Wu, J.2
Steichen, J.M.3
Kornev, A.P.4
Deal, M.S.5
Li, S.6
Sankaran, B.7
Woods Jr., V.L.8
Taylor, S.S.9
-
61
-
-
48249116424
-
Congenital disease SNPs target lineage specific structural elements in protein kinases
-
doi:10.1073/pnas. 0802403105
-
Torkamani, A., Kannan, N., Taylor, S. S. & Schork, N. J. 2008 Congenital disease SNPs target lineage specific structural elements in protein kinases. Proc. Natl Acad. Sci. USA 105, 9011-9016. (doi:10.1073/pnas. 0802403105)
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9011-9016
-
-
Torkamani, A.1
Kannan, N.2
Taylor, S.S.3
Schork, N.J.4
-
62
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
doi:10.1016/S0959-440X(97)80146-7
-
Sicheri, F. & Kuriyan, J. 1997 Structures of Src-family tyrosine kinases. Curr. Opin. Struct. Biol. 7, 777-785. (doi:10.1016/S0959-440X(97)80146-7)
-
(1997)
Curr. Opin. Struct. Biol.
, vol.7
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
63
-
-
13244291292
-
Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA
-
doi:10.1126/science.1104607
-
Kim, C., Xuong, N. H. & Taylor, S. S. 2005 Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA. Science 307, 690-696. (doi:10.1126/science.1104607)
-
(2005)
Science
, vol.307
, pp. 690-696
-
-
Kim, C.1
Xuong, N.H.2
Taylor, S.S.3
-
64
-
-
0023885305
-
The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
-
doi:10.1126/science.3291115
-
Hanks, S. K., Quinn, A. M. & Hunter, T. 1988 The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241, 42-52. (doi:10.1126/science.3291115)
-
(1988)
Science
, vol.241
, pp. 42-52
-
-
Hanks, S.K.1
Quinn, A.M.2
Hunter, T.3
-
65
-
-
0030581751
-
How do protein kinases recognize their substrates?
-
doi:10.1016/S0167-4889(96)00083-3
-
Pinna, L. A. & Ruzzene, M. 1996 How do protein kinases recognize their substrates? Biochim. Biophys. Acta 1314, 191-225. (doi:10.1016/S0167-4889(96)00083-3)
-
(1996)
Biochim. Biophys. Acta
, vol.1314
, pp. 191-225
-
-
Pinna, L.A.1
Ruzzene, M.2
-
66
-
-
0029644242
-
Activity of theMAP kinaseERK2 is controlled by a flexible surface loop
-
doi:10.1016/ S0969-2126(01)00160-5
-
Zhang, J., Zhang, F., Ebert, D., Cobb, M.H. &Goldsmith, E. J. 1995 Activity of theMAP kinaseERK2 is controlled by a flexible surface loop. Structure 3, 299-307. (doi:10.1016/ S0969-2126(01)00160-5)
-
(1995)
Structure
, vol.3
, pp. 299-307
-
-
Zhang, J.1
Zhang, F.2
Ebert, D.3
Cobb, M.H.4
Goldsmith, E.J.5
-
67
-
-
0034743516
-
Structure of GSK3beta reveals a primed phosphorylation mechanism
-
doi:10.1038/89624
-
ter Haar, E., Coll, J. T., Austen, D. A., Hsiao, H. M., Swenson, L. & Jain, J. 2001 Structure of GSK3beta reveals a primed phosphorylation mechanism. Nat. Struct. Biol. 8, 593-596. (doi:10.1038/89624)
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 593-596
-
-
ter Haar, E.1
Coll, J.T.2
Austen, D.A.3
Hsiao, H.M.4
Swenson, L.5
Jain, J.6
-
68
-
-
0035665719
-
The structure of phosphorylated GSK-3b complexed with a peptide, FRATtide, that inhibits b-catenin phosphorylation
-
doi:10.1016/S0969-2126(01)00679-7
-
Bax, B. et al. 2001 The structure of phosphorylated GSK-3b complexed with a peptide, FRATtide, that inhibits b-catenin phosphorylation. Structure 9, 1143-1152. (doi:10.1016/S0969-2126(01)00679-7)
-
(2001)
Structure
, vol.9
, pp. 1143-1152
-
-
Bax, B.1
-
69
-
-
3343024236
-
Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2a
-
doi:10.1110/ps.04637904
-
Kannan, N. & Neuwald, A. F. 2004 Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2a. Protein Sci. 13, 2059-2077. (doi:10.1110/ps.04637904)
-
(2004)
Protein Sci.
, vol.13
, pp. 2059-2077
-
-
Kannan, N.1
Neuwald, A.F.2
-
70
-
-
33747359918
-
The role of the phospho-CDK2/ cyclin A recruitment site in substrate recognition
-
doi:10.1074/jbc. M600480200
-
Cheng, K. Y. et al. 2006 The role of the phospho-CDK2/ cyclin A recruitment site in substrate recognition. J. Biol. Chem. 281, 23 167-23 179. (doi:10.1074/jbc. M600480200)
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23167-23179
-
-
Cheng, K.Y.1
-
71
-
-
0030866897
-
Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
-
doi:10.1016/S0092-8674(00)80351-7
-
Canagarajah, B. J., Khokhlatchev, A., Cobb, M. H. & Goldsmith, E. J. 1997 Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell 90, 859-869. (doi:10.1016/S0092-8674(00)80351-7)
-
(1997)
Cell
, vol.90
, pp. 859-869
-
-
Canagarajah, B.J.1
Khokhlatchev, A.2
Cobb, M.H.3
Goldsmith, E.J.4
-
72
-
-
0347520938
-
Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A
-
doi:10.1021/bi0268910
-
Lowe, E. D., Tews, I., Cheng, K. Y., Brown, N. R., Gul, S., Noble, M. E., Gamblin, S. J. & Johnson, L. N. 2002 Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. Biochemistry 41, 15 625-15 634. (doi:10.1021/bi0268910)
-
(2002)
Biochemistry
, vol.41
, pp. 15625-15634
-
-
Lowe, E.D.1
Tews, I.2
Cheng, K.Y.3
Brown, N.R.4
Gul, S.5
Noble, M.E.6
Gamblin, S.J.7
Johnson, L.N.8
-
73
-
-
53149130515
-
The crystal structure of JNK2 reveals conformational flexibility in the MAP kinase insert and indicates its involvement in the regulation of catalytic activity
-
doi:10.1016/j.jmb. 2008.08.086
-
Shaw, D., Wang, S. M., Villasenor, A. G., Tsing, S., Walter, D., Browner, M. F., Barnett, J. & Kuglstatter, A. 2008 The crystal structure of JNK2 reveals conformational flexibility in the MAP kinase insert and indicates its involvement in the regulation of catalytic activity. J. Mol. Biol. 383, 885-893. (doi:10.1016/j.jmb. 2008.08.086)
-
(2008)
J. Mol. Biol.
, vol.383
, pp. 885-893
-
-
Shaw, D.1
Wang, S.M.2
Villasenor, A.G.3
Tsing, S.4
Walter, D.5
Browner, M.F.6
Barnett, J.7
Kuglstatter, A.8
-
74
-
-
36348961352
-
A novel lipid binding site formed by the MAP kinase insert in p38 alpha
-
doi:10.1016/j. jmb.2007.09.002
-
Diskin, R., Engelberg, D. & Livnah, O. 2008 A novel lipid binding site formed by the MAP kinase insert in p38 alpha. J. Mol. Biol. 375, 70-79. (doi:10.1016/j. jmb.2007.09.002)
-
(2008)
J. Mol. Biol.
, vol.375
, pp. 70-79
-
-
Diskin, R.1
Engelberg, D.2
Livnah, O.3
-
75
-
-
33846590132
-
The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module
-
doi:10. 1073/pnas.0610251104
-
Kannan, N., Haste, N., Taylor, S. S. & Neuwald, A. F. 2007 The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proc. Natl Acad. Sci. USA 104, 1272-1277. (doi:10. 1073/pnas.0610251104)
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1272-1277
-
-
Kannan, N.1
Haste, N.2
Taylor, S.S.3
Neuwald, A.F.4
-
76
-
-
33750047550
-
The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Ca
-
doi:10.1074/jbc. M511278200
-
Yeong, S. S. et al. 2006 The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Ca. J. Biol. Chem. 281, 30 768-30 781. (doi:10.1074/jbc. M511278200)
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30768-30781
-
-
Yeong, S.S.1
-
77
-
-
64149128633
-
The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail
-
doi:10.1074/jbc.M808436200
-
Gould, C. M., Kannan, N., Taylor, S. S. & Newton, A. C. 2009 The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. J. Biol. Chem. 284, 4921-4935. (doi:10.1074/jbc.M808436200)
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4921-4935
-
-
Gould, C.M.1
Kannan, N.2
Taylor, S.S.3
Newton, A.C.4
-
78
-
-
79958045176
-
Characterization of the mechanisms controlling Greatwall activity
-
doi:10.1128/MCB.00753-10
-
Vigneron, S., Gharbi-Ayachi, A., Raymond, A. A., Burgess, A., Labbe, J. C., Labesse, G., Monsarrat, B., Lorca, T. & Castro, A. 2011 Characterization of the mechanisms controlling Greatwall activity. Mol. Cell Biol. 31, 2262-2275. (doi:10.1128/MCB.00753-10)
-
(2011)
Mol. Cell Biol.
, vol.31
, pp. 2262-2275
-
-
Vigneron, S.1
Gharbi-Ayachi, A.2
Raymond, A.A.3
Burgess, A.4
Labbe, J.C.5
Labesse, G.6
Monsarrat, B.7
Lorca, T.8
Castro, A.9
-
79
-
-
1342342993
-
PDK1, the master regulator of AGC kinase signal transduction
-
doi:10.1016/j.semcdb.2003.12.022
-
Mora, A., Komander, D., van Aalten, D. M. & Alessi, D. R. 2004 PDK1, the master regulator of AGC kinase signal transduction. Semin. Cell Dev. Biol. 15, 161-170. (doi:10.1016/j.semcdb.2003.12.022)
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 161-170
-
-
Mora, A.1
Komander, D.2
van Aalten, D.M.3
Alessi, D.R.4
-
80
-
-
67650082449
-
A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1
-
doi:10.1002/pro.146
-
Romano, R. A., Kannan, N., Kornev, A. P., Allison, C. J. & Taylor, S. S. 2009 A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1. Protein Sci. 18, 1486-1497. (doi:10.1002/pro.146)
-
(2009)
Protein Sci.
, vol.18
, pp. 1486-1497
-
-
Romano, R.A.1
Kannan, N.2
Kornev, A.P.3
Allison, C.J.4
Taylor, S.S.5
-
81
-
-
0035929146
-
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region
-
doi:10.1016/S0092-8674(01)00496-2
-
Wybenga-Groot, L. E., Baskin, B., Ong, S. H., Tong, J., Pawson, T. & Sicheri, F. 2001 Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region. Cell 106, 745-757. (doi:10.1016/S0092-8674(01)00496-2)
-
(2001)
Cell
, vol.106
, pp. 745-757
-
-
Wybenga-Groot, L.E.1
Baskin, B.2
Ong, S.H.3
Tong, J.4
Pawson, T.5
Sicheri, F.6
-
82
-
-
0842310394
-
The structural basis for autoinhibition of FLT3 by the juxtamembrane domain
-
doi:10.1016/S1097-2765(03)00505-7
-
Griffith, J., Black, J., Faerman, C., Swenson, L., Wynn, M., Lu, F., Lippke, J. & Saxena, K. 2004 The structural basis for autoinhibition of FLT3 by the juxtamembrane domain. Mol. Cell 13, 169-178. (doi:10.1016/S1097-2765(03)00505-7)
-
(2004)
Mol. Cell
, vol.13
, pp. 169-178
-
-
Griffith, J.1
Black, J.2
Faerman, C.3
Swenson, L.4
Wynn, M.5
Lu, F.6
Lippke, J.7
Saxena, K.8
-
83
-
-
0036710123
-
Crystal structure of the MuSK tyrosine kinase: Insights into receptor autoregulation
-
doi:10.1016/S0969-2126(02)00814-6
-
Till, J. H., Becerra, M., Watty, A., Lu, Y., Ma, Y., Neubert, T. A., Burden, S. J. & Hubbard, S. R. 2002 Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation. Structure 10, 1187-1196. (doi:10.1016/S0969-2126(02)00814-6)
-
(2002)
Structure
, vol.10
, pp. 1187-1196
-
-
Till, J.H.1
Becerra, M.2
Watty, A.3
Lu, Y.4
Ma, Y.5
Neubert, T.A.6
Burden, S.J.7
Hubbard, S.R.8
-
84
-
-
67449146917
-
The juxtamembrane region of the EGF receptor functions as an activation domain
-
doi:10.1016/j.molcel.2009.04.034
-
Red Brewer, M., Choi, S. H., Alvarado, D., Moravcevic, K., Pozzi, A., Lemmon, M. A. & Carpenter, G. 2009 The juxtamembrane region of the EGF receptor functions as an activation domain. Mol. Cell 34, 641-651. (doi:10.1016/j.molcel.2009.04.034)
-
(2009)
Mol. Cell
, vol.34
, pp. 641-651
-
-
Red Brewer, M.1
Choi, S.H.2
Alvarado, D.3
Moravcevic, K.4
Pozzi, A.5
Lemmon, M.A.6
Carpenter, G.7
-
85
-
-
67549145398
-
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment
-
doi:10.1016/j.cell.2009.04.025
-
Jura, N., Endres, N. F., Engel, K., Deindl, S., Das, R., Lamers, M. H., Wemmer, D. E., Zhang, X. & Kuriyan, J. 2009 Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 137, 1293-1307. (doi:10.1016/j.cell.2009.04.025)
-
(2009)
Cell
, vol.137
, pp. 1293-1307
-
-
Jura, N.1
Endres, N.F.2
Engel, K.3
Deindl, S.4
Das, R.5
Lamers, M.H.6
Wemmer, D.E.7
Zhang, X.8
Kuriyan, J.9
-
86
-
-
78650767757
-
Co-conserved features associated with cis regulation of ErbB tyrosine kinases
-
doi:10. 1371/journal.pone.0014310
-
Mirza, A., Mustafa, M., Talevich, E. & Kannan, N. 2010 Co-conserved features associated with cis regulation of ErbB tyrosine kinases. PLoS ONE 5, e14310. (doi:10. 1371/journal.pone.0014310)
-
(2010)
PLoS ONE
, vol.5
-
-
Mirza, A.1
Mustafa, M.2
Talevich, E.3
Kannan, N.4
-
87
-
-
76349120152
-
Evolution of domain combinations in protein kinases and its implications for functional diversity
-
doi:10.1016/j.pbiomolbio. 2009.12.009
-
Deshmukh, K., Anamika, K. & Srinivasan, N. 2009 Evolution of domain combinations in protein kinases and its implications for functional diversity. Prog. Biophys. Mol. Biol. 102, 1-15. (doi:10.1016/j.pbiomolbio. 2009.12.009)
-
(2009)
Prog. Biophys. Mol. Biol.
, vol.102
, pp. 1-15
-
-
Deshmukh, K.1
Anamika, K.2
Srinivasan, N.3
-
88
-
-
77951159012
-
Rapid diversification of cell signaling phenotypes by modular domain recombination
-
doi:10.1126/science.1182376
-
Peisajovich, S. G., Garbarino, J. E., Wei, P. & Lim, W. A. 2010 Rapid diversification of cell signaling phenotypes by modular domain recombination. Science 328, 368-372. (doi:10.1126/science.1182376)
-
(2010)
Science
, vol.328
, pp. 368-372
-
-
Peisajovich, S.G.1
Garbarino, J.E.2
Wei, P.3
Lim, W.A.4
-
89
-
-
0141757323
-
Reprogramming control of an allosteric signaling switch through modular recombination
-
doi:10.1126/science.1085945
-
Dueber, J. E., Yeh, B. J., Chak, K. & Lim, W. A. 2003 Reprogramming control of an allosteric signaling switch through modular recombination. Science 301, 1904-1908. (doi:10.1126/science.1085945)
-
(2003)
Science
, vol.301
, pp. 1904-1908
-
-
Dueber, J.E.1
Yeh, B.J.2
Chak, K.3
Lim, W.A.4
-
90
-
-
77956141521
-
Phosphotyrosine signaling: Evolving a new cellular communication system
-
doi:10.1016/j.cell.2010.08.023
-
Lim, W. A. & Pawson, T. 2010 Phosphotyrosine signaling: evolving a new cellular communication system. Cell 142, 661-667. (doi:10.1016/j.cell.2010.08.023)
-
(2010)
Cell
, vol.142
, pp. 661-667
-
-
Lim, W.A.1
Pawson, T.2
-
91
-
-
0028859279
-
Protein modules and signalling networks
-
doi:10.1038/373573a0
-
Pawson, T. 1995 Protein modules and signalling networks. Nature 373, 573-580. (doi:10.1038/373573a0)
-
(1995)
Nature
, vol.373
, pp. 573-580
-
-
Pawson, T.1
-
92
-
-
0035575586
-
SH2 domains, interaction modules and cellular wiring
-
doi:10.1016/S0962-8924(01)02154-7
-
Pawson, T., Gish, G. D. & Nash, P. 2001 SH2 domains, interaction modules and cellular wiring. Trends Cell. Biol. 11, 504-511. (doi:10.1016/S0962-8924(01)02154-7)
-
(2001)
Trends Cell. Biol.
, vol.11
, pp. 504-511
-
-
Pawson, T.1
Gish, G.D.2
Nash, P.3
-
93
-
-
68749107059
-
Protein sectors: Evolutionary units of threedimensional structure
-
doi:10. 1016/j.cell.2009.07.038
-
Halabi, N., Rivoire, O., Leibler, S. & Ranganathan, R. 2009 Protein sectors: evolutionary units of threedimensional structure. Cell 138, 774-786. (doi:10. 1016/j.cell.2009.07.038)
-
(2009)
Cell
, vol.138
, pp. 774-786
-
-
Halabi, N.1
Rivoire, O.2
Leibler, S.3
Ranganathan, R.4
-
94
-
-
77957274298
-
An interdomain sector mediating allostery in Hsp70 molecular chaperones
-
doi:10. 1038/msb.2010.65
-
Smock, R. G., Rivoire, O., Russ, W. P., Swain, J. F., Leibler, S., Ranganathan, R. & Gierasch, L. M. 2010 An interdomain sector mediating allostery in Hsp70 molecular chaperones. Mol. Syst. Biol. 6, 414. (doi:10. 1038/msb.2010.65)
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 414
-
-
Smock, R.G.1
Rivoire, O.2
Russ, W.P.3
Swain, J.F.4
Leibler, S.5
Ranganathan, R.6
Gierasch, L.M.7
-
95
-
-
34548815693
-
Modular architecture of protein structures and allosteric communications: Potential implications for signaling proteins and regulatory linkages
-
doi:10.1186/gb-2007-8-5-r92
-
Del Sol, A., Arauzo-Bravo, M. J., Amoros, D. & Nussinov, R. 2007 Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages. Genome Biol. 8, R92. (doi:10.1186/gb-2007-8-5-r92)
-
(2007)
Genome Biol.
, vol.8
-
-
Del Sol, A.1
Arauzo-Bravo, M.J.2
Amoros, D.3
Nussinov, R.4
-
96
-
-
38049029758
-
The modular organization of domain structures: Insights into protein-protein binding
-
doi:10. 1371/journal.pcbi.0030239
-
del Sol, A. & Carbonell, P. 2007 The modular organization of domain structures: insights into protein-protein binding. PLoS Comput. Biol. 3, e239. (doi:10. 1371/journal.pcbi.0030239)
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
del Sol, A.1
Carbonell, P.2
-
97
-
-
64849101493
-
Protein dynamism and evolvability
-
(doi:10.1126/science.1169375)
-
Tokuriki, N. & Tawfik, D. S. 2009 Protein dynamism and evolvability. Science 324, 203-207. (doi:10.1126/science.
-
(2009)
Science
, vol.324
, pp. 203-207
-
-
Tokuriki, N.1
Tawfik, D.S.2
|