A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold

Journal of Molecular Biology

Volumn 415, Issue 4, 2012, Pages 666-679

  Yang, Jie ^a   Wu, Jian ^a   Steichen, Jon M ^a   Kornev, Alexandr P ^a   Deal, Michael S ^a   Li, Sheng ^a   Sankaran, Banumathi ^b   Woods Jr , Virgil L ^c   Taylor, Susan S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

cAMP dependent protein kinase; catalysis; crystal structure; hydrogen deuterium exchange; ion pair

Indexed keywords

ARGININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUTAMINE; MUTANT PROTEIN; PHOSPHATIDYLINOSITIDE; PROTEIN KINASE; SODIUM CHLORIDE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBSTRATE; EUKARYOTE; FLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

EUKARYOTA; MURINAE;

EID: 84856232223     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.11.035     Document Type: Article

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