Evidence Implicating Matrix Metalloproteinases in the Mechanism Underlying Accumulation of IL-1β and Neuronal Apoptosis in the Neocortex of HIV/gp120-Exposed Rats

International Review of Neurobiology

Volumn 82, Issue , 2007, Pages 407-421

  Russo, Rossella ^a,b   Siviglia, Elisa ^c   Gliozzi, Micaela ^c   Amantea, Diana ^a   Paoletti, Annamaria ^d   Berliocchi, Laura ^a,e   Bagetta, G ^a   Corasaniti, M Tiziana ^c,e  

^a UNIVERSITY OF CALABRIA   (Italy)

^b BURNHAM INSTITUTE   (United States)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d INSTITUTE OF NEUROLOGICAL SCIENCES   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDE; ENZYME INHIBITOR; GELATINASE A; GELATINASE B; GLYCOPROTEIN GP 120; ILOMASTAT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MATRIX METALLOPROTEINASE;

ANIMAL; APOPTOSIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; METABOLISM; NEOCORTEX; NERVE CELL; PATHOLOGY; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; REVIEW; WISTAR RAT;

ANIMALS; APOPTOSIS; CASPASE 1; DIPEPTIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIV ENVELOPE PROTEIN GP120; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; NEOCORTEX; NEURONS; RATS; RATS, WISTAR;

EID: 34547403610     PISSN: 00747742     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7742(07)82023-X     Document Type: Review

References (50)

1. Adair J.C., Charlie J., Dencoff J.E., Kaye J.A., Quinn J.F., Camicioli R.M., Stetler-Stevenson W.G., and Rosenberg G.A. Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease. Stroke 35 (2004) 159-162
2. Allan S.M., Tyrrell P.J., and Rothwell N.J. Interleukin-1 and neuronal injury. Nat. Rev. Immunol. 5 (2005) 629-640
3. Bagetta G., Corasaniti M.T., Berliocchi L., Navarra M., Finazzi-Agro A., and Nisticó G. HIV-1 gp120 produces DNA fragmentation in the cerebral cortex of rat. Biochem. Biophys. Res. Commun. 211 (1995) 130-136
4. Bagetta G., Corasaniti M.T., Malorni W., Rainaldi G., Berliocchi L., Finazzi-Agro A., and Nisticó G. The HIV-1 gp120 causes ultrastructural changes typical of apoptosis in the rat cerebral cortex. Neuroreport 7 (1996) 1722-1724
5. Bagetta G., Corasaniti M.T., Berliocchi L., Nistico R., Giammarioli A.M., Malorni W., Aloe L., and Finazzi-Agro A. Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat. Neuroscience 89 (1999) 1051-1066
6. Cerretti D.P., Kozlosky C.J., Mosley B., Nelson N., Van Ness K., Greenstreet T.A., March C.J., Kronheim S.R., Druck T., Cannizzaro L.A., Huebner K., and Black R.A. Molecular cloning of the interleukin-1 beta converting enzyme. Science 256 (1992) 97-100
7. Chauvet N., Palin K., Verrier D., Poole S., Dantzer R., and Lestage J. Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide. Eur. J. Neurosci. 14 (2001) 609-617
8. Conant K., McArthur J.C., Griffin D.E., Sjulson L., Wahl L.M., and Irani D.N. Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia. Ann. Neurol. 46 (1999) 391-398
9. Corasaniti M.T., Turano P., Bilotta A., Malorni W., Stringaro A.R., Nisticó R., Finazzi-Agro A., and Bagetta G. Evidence that increases of mitochondrial immunoreactive IL-1beta by HIV-1 gp120 implicate in situ cleavage of pro-IL-1beta in the neocortex of rat. J. Neurochem. 78 (2001) 611-618
10. Corasaniti M.T., Maccarrone M., Nisticò R., Malorni W., Rotiroti D., and Bagetta G. Exploitation of the HIV-1 coat protein, gp120, in neurodegenerative studies in vivo. J. Neurochem. 79 (2001) 1-8
11. Corasaniti M.T., Piccirilli S., Paoletti A., Nisticó R., Stringaro A., Malorni W., Finazzi-Agró A., and Bagetta G. Evidence that the HIV-1 coat protein gp120 causes neuronal apoptosis in the neocortex of rat via a mechanism involving CXCR4 chemokine receptor. Neurosci. Lett. 312 (2001) 67-70
12. Corasaniti M.T., Russo R., Amantea D., Gliozzi M., Siviglia E., Stringaro A.R., Malorni W., Melino G., and Bagetta G. Neuroprotection by the caspase-1 inhibitor Ac-YVAD-(acyloxy)mk in experimental neuroAIDS is independent from IL-1beta generation. Cell Death Differ. 12 (2005) 999-1001
13. Deb S., and Gottschall P.E. Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides. J. Neurochem. 66 (1996) 1641-1647
14. Dinarello C.A. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann. N. Y. Acad. Sci. 856 (1998) 1-11
15. Fantuzzi G., Ku G., Harding M.W., Livingston D.J., Sipe J.D., Kuida K., Flavell R.A., and Dinarello C.A. Response to local inflammation of IL-1 beta-converting enzyme-deficient mice. J. Immunol. 158 (1997) 1818-1824
16. Garcia-Calvo M., Peterson E.P., Leiting B., Ruel R., Nicholson D.W., and Thornberry N.A. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J. Biol. Chem. 273 (1998) 32608-32613
17. Gasche Y., Soccal P.M., Kanemitsu M., and Copin J.C. Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain. Front. Biosci. 11 (2006) 1289-1301
18. Gavrieli Y., Sherman Y., and Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119 (1992) 493-501
19. Gendelman H.E., Grant I., Lipton S.A., Everall I., and Swindells S. "The Neurology of AIDS,". 2nd (2005), Oxford University Press, London
20. Gijbels K., Masure S., Carton H., and Opdenakker G. Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J. Neuroimmunol. 41 (1992) 29-34
21. Gottschall P.E., and Yu X. Cytokines regulate gelatinase A and B (Matrix Metalloproteinases 2 and 9) activity in cultured rat astrocytes. J. Neurochem. 64 (1995) 1513-1520
22. Gu Z., Kaul M., Yan B., Kridel S.J., Cui J., Strongin A., Smith J.W., Liddington R.C., and Lipton S.A. S-nitrosylation of matrix metalloproteinases: Signaling pathway to neuronal cell death. Science 297 (2002) 1186-1190
23. Hagan P., Poole S., Bristow A.F., Tilders F., and Silverstein F.S. Intracerebral NMDA injection stimulates production of interleukin-1β in perinatal rat brain. J. Neurochem. 67 (1996) 2215-2218
24. Kaul M., Garden G.A., and Lipton S.A. Pathways to neuronal injury and apoptosis in HIV associated dementia. Nature 410 (2001) 988-994
25. Levy D.E., Lapierre F., Liang W., Ye W., Lange C.W., Li X., Grobelny D., Casabonne M., Tyrrell D., Holme K., Nadzan A., and Galardy R.E. Matrix metalloproteinase inhibitors: A structure-activity study. J. Med. Chem. 41 (1998) 199-223
26. Lipton S.A., and Gendelman H.E. Dementia associated with the acquired immunodeficiency syndrome. New Engl. J. Med. 332 (1995) 934-940
27. Liuzzi G.M., Mastroianni C.M., Santacroce M.P., Fanelli M., D'Agostino C., Vullo V., and Riccio P. Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases. J. Neurovirol. 6 (2000) 156-163
28. Lukes A., Mun-Bryce S., Lukes M., and Rosenberg G.A. Extracellular matrix degradation by metalloproteinases and central nervous system diseases. Mol. Neurobiol. 19 (1999) 267-284
29. Marshall D.C., Wyss-Coray T., and Abraham C.R. Induction of matrix metalloproteinase-2 in human immunodeficiency virus-1 glycoprotein 120 transgenic mouse brains. Neurosci. Lett. 254 (1998) 97-100
30. Masliah E., Ge N., Achim C.L., Hansen L.A., and Wiley C.A. Selective neuronal vulnerability in HIV encephalitis. J. Neuropathol. Exp. Neurol. 51 (1992) 585-593
31. Mathiak G., Grass G., Herzmann T., Luebke T., Zetina C.C., Bohlen S.A., Neville L.F., and Hoelscher A.H. Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses. Br. J. Pharmacol. 131 (2000) 383-386
32. Milligan C.E., Prevette D., Yaginuma H., Homma S., Cardwell C., Fritz L.C., Tomaselli K.J., Oppenheim R.W., and Schwartz L.M. Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron 15 (1995) 385-393
33. Nylander-Lundqvist E., Back O., and Egelrud T. IL-1 beta activation in human epidermis. J. Immunol. 157 (1996) 1699-1704
34. Paxinos G., and Watson C. "The Rat Brain in Stereotaxic Coordinates." (1998), Academic Press, San Diego, CA
35. Planas A.M., Sole S., and Justicia C. Expression and activation of matrix metalloproteinase-2 and -9 in rat brain after transient focal cerebral ischemia. Neurobiol. Dis. 8 (2001) 834-846
36. Price R.W., and Brew B.J. The AIDS dementia complex. J. Infect. Dis. 158 (1988) 1079-1083
37. Rano T.A., Timkey T., Peterson E.P., Rotonda J., Nicholson D.W., Becker J.W., Chapman K.T., and Thornberry N.A. A combinatorial approach for determining protease specificities: Application to interleukin-1beta converting enzyme (ICE). Chem. Biol. 4 (1997) 149-155
38. Rosenberg G.A. Matrix metalloproteinases in neuroinflammation. Glia 39 (2002) 279-291
39. Rosenberg G.A., Dencoff J.E., Correa Jr. N., Reiners M., and Ford C.C. Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: Relation to blood-brain barrier injury. Neurology 46 (1996) 1626-1632
40. Rothwell N.J., and Luheshi G.N. Interleukin 1 in the brain: Biology, pathology and therapeutic target. Trends Neurosci. 23 (2000) 618-625
41. Schonbeck U., Mach F., and Libby P. Generation of biologically active IL-1 beta by matrix metalloproteinases: A novel caspase-1-independent pathway of IL-1 beta processing. J. Immunol. 161 (1998) 3340-3346
42. Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., Elliston K.O., Ayala J.M., et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356 (1992) 768-774
43. Toggas S.M., Masliah E., Rockenstein E.M., Rall G.F., Abraham C.R., and Mucke L. Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature 367 (1994) 188-193
44. Vecil G.G., Larsen P.H., Corley S.M., Herx L.M., Besson A., Goodyer C.G., and Yong V.W. Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo. J. Neurosci. Res. 61 (2000) 212-224
45. Visse R., and Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry. Circ. Res. 92 (2003) 827-839
46. Wu C.Y., Hsieh H.L., Jou M.J., and Yang C.M. Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-kappa B in interleukin-1beta-induced matrix metalloproteinase-9 expression in rat brain astrocytes. J. Neurochem. 90 (2004) 1477-1488
47. Xie Z., Singh M., and Singh K. Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1beta. J. Biol. Chem. 279 (2004) 39513-39519
48. Yao C., Karabasil M.R., Purwanti N., Li X., Akamatsu T., Kanamori N., and Hosoi K. Tissue Kallikrein mK13 is a candidate processing enzyme for the precursor of interleukin-1beta in the submandibular gland of mice. J. Biol. Chem. 281 (2006) 7968-7976
49. Yong V.W. Metalloproteinases: Mediators of pathology and regeneration in the CNS. Nat. Rev. Neurosci. 6 (2005) 931-944
50. Zhang J.W., and Gottschall P.E. Zymographic measurement of gelatinase activity in brain tissue after detergent extraction and affinity-support purification. J. Neurosci. Methods 76 (1997) 15-20