T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand

Nature

Volumn 436, Issue 7050, 2005, Pages 578-582

  Choudhuri, Kaushik ^a   Wiseman, David ^a   Brown, Marion H ^a   Gould, Keith ^b   Van Der Merwe, P Anton ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CELL CULTURE; COMPLEXATION; HISTOLOGY; IMMUNOLOGY; SIGNALING;

ANTIGEN-PRESENTING CELLS (APC); IMMUNE RESPONSES; SIGNALLING; T-CELL ANTIGEN RECEPTOR (TCR);

CELLS;

CD45 ANTIGEN; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR; ANTIGEN; HISTOCOMPATIBILITY ANTIGEN; LIGAND; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE;

IMMUNE RESPONSE;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; ANIMAL; CATTLE; CELL LINE; CHEMISTRY; CHO CELL; HAMSTER; IMMUNOLOGY; KINETICS; LYMPHOCYTE ACTIVATION; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ANIMALIA;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS; ANTIGENS, CD45; CATTLE; CELL LINE; CHO CELLS; CRICETINAE; HISTOCOMPATIBILITY ANTIGENS; KINETICS; LIGANDS; LYMPHOCYTE ACTIVATION; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 23144455728     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03843     Document Type: Article

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