메뉴 건너뛰기




Volumn 32, Issue 30, 2012, Pages 10423-10437

Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN [1-40]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CASPASE 3; GLIAL FIBRILLARY ACIDIC PROTEIN; NEURON SPECIFIC NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

EID: 84864271370     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5491-11.2012     Document Type: Article
Times cited : (53)

References (77)
  • 1
    • 70450184309 scopus 로고    scopus 로고
    • Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice
    • Anderson J, Sandhir R, Hamilton ES, Berman NE (2009) Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice. J Neurotrauma 26:1557-1566.
    • (2009) J Neurotrauma , vol.26 , pp. 1557-1566
    • Anderson, J.1    Sandhir, R.2    Hamilton, E.S.3    Berman, N.E.4
  • 2
    • 33646373685 scopus 로고    scopus 로고
    • Traumatic brain injury in mice deficient in Bid: Effects on histopathology and functional outcome
    • Bermpohl D, You Z, Korsmeyer SJ, Moskowitz MA, Whalen MJ (2006) Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome. J Cereb Blood Flow Metab 26:625-633.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 625-633
    • Bermpohl, D.1    You, Z.2    Korsmeyer, S.J.3    Moskowitz, M.A.4    Whalen, M.J.5
  • 3
    • 1842728419 scopus 로고    scopus 로고
    • Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease betasecretase (BACE-1)
    • Blasko I, Beer R, Bigl M, Apelt J, Franz G, Rudzki D, Ransmayr G, Kampfl A, Schliebs R (2004) Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease betasecretase (BACE-1). J Neural Transm 111:523-536.
    • (2004) J Neural Transm , vol.111 , pp. 523-536
    • Blasko, I.1    Beer, R.2    Bigl, M.3    Apelt, J.4    Franz, G.5    Rudzki, D.6    Ransmayr, G.7    Kampfl, A.8    Schliebs, R.9
  • 5
    • 59049087888 scopus 로고    scopus 로고
    • MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1
    • Boissonneault V, Plante I, Rivest S, Provost P (2009) MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1. J Biol Chem 284:1971-1981.
    • (2009) J Biol Chem , vol.284 , pp. 1971-1981
    • Boissonneault, V.1    Plante, I.2    Rivest, S.3    Provost, P.4
  • 6
    • 34248178463 scopus 로고    scopus 로고
    • Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides
    • Bourne KZ, Ferrari DC, Lange-Dohna C, Rossner S, Wood TG, Perez-Polo JR (2007) Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides. J Neurosci Res 85:1194-1204.
    • (2007) J Neurosci Res , vol.85 , pp. 1194-1204
    • Bourne, K.Z.1    Ferrari, D.C.2    Lange-Dohna, C.3    Rossner, S.4    Wood, T.G.5    Perez-Polo, J.R.6
  • 7
    • 3242770404 scopus 로고    scopus 로고
    • Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma
    • Chen XH, Siman R, Iwata A, Meaney DF, Trojanowski JQ, Smith DH (2004) Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma. Am J Pathol 165:357-371.
    • (2004) Am J Pathol , vol.165 , pp. 357-371
    • Chen, X.H.1    Siman, R.2    Iwata, A.3    Meaney, D.F.4    Trojanowski, J.Q.5    Smith, D.H.6
  • 8
    • 61649120633 scopus 로고    scopus 로고
    • A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury
    • Chen XH, Johnson VE, Uryu K, Trojanowski JQ, Smith DH (2009) A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury. Brain Pathol 19:214-223.
    • (2009) Brain Pathol , vol.19 , pp. 214-223
    • Chen, X.H.1    Johnson, V.E.2    Uryu, K.3    Trojanowski, J.Q.4    Smith, D.H.5
  • 10
    • 0347356360 scopus 로고    scopus 로고
    • Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1
    • Christensen MA, Zhou W, Qing H, Lehman A, Philipsen S, Song W (2004) Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1. Mol Cell Biol 24:865-874.
    • (2004) Mol Cell Biol , vol.24 , pp. 865-874
    • Christensen, M.A.1    Zhou, W.2    Qing, H.3    Lehman, A.4    Philipsen, S.5    Song, W.6
  • 13
    • 57649217285 scopus 로고    scopus 로고
    • The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology
    • Cole SL, Vassar R (2008) The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology. J Biol Chem 283:29621-29625.
    • (2008) J Biol Chem , vol.283 , pp. 29621-29625
    • Cole, S.L.1    Vassar, R.2
  • 19
    • 79955577221 scopus 로고    scopus 로고
    • Prevalence, management and outcomes of traumatic brain injury patients admitted to an Irish intensive care unit
    • Frohlich S, Johnson P, Moriarty J (2011) Prevalence, management and outcomes of traumatic brain injury patients admitted to an Irish intensive care unit. Ir J Med Sci 180:423-427.
    • (2011) Ir J Med Sci , vol.180 , pp. 423-427
    • Frohlich, S.1    Johnson, P.2    Moriarty, J.3
  • 20
    • 0036718272 scopus 로고    scopus 로고
    • Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease
    • Fukumoto H, Cheung BS, Hyman BT, Irizarry MC (2002) Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 59:1381-1389.
    • (2002) Arch Neurol , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 22
    • 14744306422 scopus 로고    scopus 로고
    • Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: More than a focal brain injury
    • Hall ED, Sullivan PG, Gibson TR, Pavel KM, Thompson BM, Scheff SW (2005) Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: more than a focal brain injury. J Neurotrauma 22:252-265.
    • (2005) J Neurotrauma , vol.22 , pp. 252-265
    • Hall, E.D.1    Sullivan, P.G.2    Gibson, T.R.3    Pavel, K.M.4    Thompson, B.M.5    Scheff, S.W.6
  • 23
    • 15744380393 scopus 로고    scopus 로고
    • GGA proteins mediate the recycling pathway of memapsin 2 (BACE)
    • He X, Li F, Chang WP, Tang J (2005) GGA proteins mediate the recycling pathway of memapsin 2 (BACE). J Biol Chem 280:11696-11703.
    • (2005) J Biol Chem , vol.280 , pp. 11696-11703
    • He, X.1    Li, F.2    Chang, W.P.3    Tang, J.4
  • 25
    • 41549124453 scopus 로고    scopus 로고
    • Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo
    • Hirata-Fukae C, Sidahmed EH, Gooskens TP, Aisen PS, Dewachter I, Devijver H, Van Leuven F, Matsuoka Y (2008) Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo. Neurosci Lett 435:186-189.
    • (2008) Neurosci Lett , vol.435 , pp. 186-189
    • Hirata-Fukae, C.1    Sidahmed, E.H.2    Gooskens, T.P.3    Aisen, P.S.4    Dewachter, I.5    Devijver, H.6    van Leuven, F.7    Matsuoka, Y.8
  • 26
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
    • Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G (2002) Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann Neurol 51:783-786.
    • (2002) Ann Neurol , vol.51 , pp. 783-786
    • Holsinger, R.M.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 27
    • 10044250141 scopus 로고    scopus 로고
    • Head injury and dementia
    • Jellinger KA (2004) Head injury and dementia. Curr Opin Neurol 17: 719-723.
    • (2004) Curr Opin Neurol , vol.17 , pp. 719-723
    • Jellinger, K.A.1
  • 28
    • 79961158069 scopus 로고    scopus 로고
    • Traumatic brain injury and amyloid-beta pathology: A link to Alzheimer's disease?
    • Johnson VE, Stewart W, Smith DH (2010) Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer's disease? Nat Rev Neurosci 11:361-370.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 361-370
    • Johnson, V.E.1    Stewart, W.2    Smith, D.H.3
  • 30
    • 0036799487 scopus 로고    scopus 로고
    • Multiple caspases are activated after traumatic brain injury: Evidence for involvement in functional outcome
    • Knoblach SM, Nikolaeva M, Huang X, Fan L, Krajewski S, Reed JC, Faden AI (2002) Multiple caspases are activated after traumatic brain injury: evidence for involvement in functional outcome. J Neurotrauma 19: 1155-1170.
    • (2002) J Neurotrauma , vol.19 , pp. 1155-1170
    • Knoblach, S.M.1    Nikolaeva, M.2    Huang, X.3    Fan, L.4    Krajewski, S.5    Reed, J.C.6    Faden, A.I.7
  • 32
    • 4344681535 scopus 로고    scopus 로고
    • Expression of the Alzheimer protease BACE1 is suppressed via its 5'- untranslated region
    • Lammich S, Schöbel S, Zimmer AK, Lichtenthaler SF, Haass C (2004) Expression of the Alzheimer protease BACE1 is suppressed via its 5'- untranslated region. EMBO Rep 5:620-625.
    • (2004) EMBO Rep , vol.5 , pp. 620-625
    • Lammich, S.1    Schöbel, S.2    Zimmer, A.K.3    Lichtenthaler, S.F.4    Haass, C.5
  • 33
    • 24644453571 scopus 로고    scopus 로고
    • The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death
    • LeBlanc AC (2005) The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death. Curr Alzheimer Res 2:389-402.
    • (2005) Curr Alzheimer Res , vol.2 , pp. 389-402
    • Leblanc, A.C.1
  • 34
    • 13844265969 scopus 로고    scopus 로고
    • BACE over expression alters the subcellular processing of APP and inhibits Abeta deposition in vivo
    • Lee EB, Zhang B, Liu K, Greenbaum EA, Doms RW, Trojanowski JQ, Lee VM (2005) BACE over expression alters the subcellular processing of APP and inhibits Abeta deposition in vivo. J Cell Biol 168:291-302.
    • (2005) J Cell Biol , vol.168 , pp. 291-302
    • Lee, E.B.1    Zhang, B.2    Liu, K.3    Greenbaum, E.A.4    Doms, R.W.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 37
    • 10944234871 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor 1 and its signaling intermediates are recruited to lipid rafts in the traumatized brain
    • Lotocki G, Alonso OF, Dietrich WD, Keane RW (2004) Tumor necrosis factor receptor 1 and its signaling intermediates are recruited to lipid rafts in the traumatized brain. J Neurosci 24:11010-11016.
    • (2004) J Neurosci , vol.24 , pp. 11010-11016
    • Lotocki, G.1    Alonso, O.F.2    Dietrich, W.D.3    Keane, R.W.4
  • 40
    • 34250641977 scopus 로고    scopus 로고
    • Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region
    • Mihailovich M, Thermann R, Grohovaz F, Hentze MW, Zacchetti D (2007) Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region. Nucleic Acids Res 35:2975-2985.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2975-2985
    • Mihailovich, M.1    Thermann, R.2    Grohovaz, F.3    Hentze, M.W.4    Zacchetti, D.5
  • 41
    • 1842610004 scopus 로고    scopus 로고
    • Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons
    • Ninan I, Arancio O (2004) Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron 42:129-141.
    • (2004) Neuron , vol.42 , pp. 129-141
    • Ninan, I.1    Arancio, O.2
  • 45
    • 65549158252 scopus 로고    scopus 로고
    • Traumatic brain injury alters expression of hippocampal microRNAs: Potential regulators of multiple pathophysiological processes
    • Redell JB, Liu Y, Dash PK (2009) Traumatic brain injury alters expression of hippocampal microRNAs: potential regulators of multiple pathophysiological processes. J Neurosci Res 87:1435-1448.
    • (2009) J Neurosci Res , vol.87 , pp. 1435-1448
    • Redell, J.B.1    Liu, Y.2    Dash, P.K.3
  • 46
  • 47
    • 25444479179 scopus 로고    scopus 로고
    • High β-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels. Implications for the treatment of Alzheimer disease
    • Rockenstein E, Mante M, Alford M, Adame A, Crews L, Hashimoto M, Esposito L, Mucke L, Masliah E (2005) High β-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels. Implications for the treatment of Alzheimer disease. J Biochem 280:32957-32967.
    • (2005) J Biochem , vol.280 , pp. 32957-32967
    • Rockenstein, E.1    Mante, M.2    Alford, M.3    Adame, A.4    Crews, L.5    Hashimoto, M.6    Esposito, L.7    Mucke, L.8    Masliah, E.9
  • 49
    • 1542357687 scopus 로고    scopus 로고
    • Differential utilization of upstream AUGs in the beta-secretase mRNA suggests that a shunting mechanism regulates translation
    • Rogers GW Jr, Edelman GM, Mauro VP (2004) Differential utilization of upstream AUGs in the beta-secretase mRNA suggests that a shunting mechanism regulates translation. Proc Natl Acad Sci U S A 101: 2794-2799.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2794-2799
    • Rogers Jr., G.W.1    Edelman, G.M.2    Mauro, V.P.3
  • 50
    • 33747347875 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of BACE1 expression-implications for Alzheimer's disease
    • Rossner S, Sastre M, Bourne K, Lichtenthaler SF (2006) Transcriptional and translational regulation of BACE1 expression-implications for Alzheimer's disease. Prog Neurobiol 79:95-111.
    • (2006) Prog Neurobiol , vol.79 , pp. 95-111
    • Rossner, S.1    Sastre, M.2    Bourne, K.3    Lichtenthaler, S.F.4
  • 51
    • 0037085571 scopus 로고    scopus 로고
    • NF-kappaB and IkappaBalpha expression following traumatic brain injury to the immature rat brain
    • Sanz O, Acarin L, González B, Castellano B (2002) NF-kappaB and IkappaBalpha expression following traumatic brain injury to the immature rat brain. J Neurosci Res 67:772-780.
    • (2002) J Neurosci Res , vol.67 , pp. 772-780
    • Sanz, O.1    Acarin, L.2    González, B.3    Castellano, B.4
  • 54
    • 0036470514 scopus 로고    scopus 로고
    • Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death
    • Singleton RH, Zhu J, Stone JR, Povlishock JT (2002) Traumatically induced axotomy adjacent to the soma does not result in acute neuronal death. J Neurosci 22:791-802.
    • (2002) J Neurosci , vol.22 , pp. 791-802
    • Singleton, R.H.1    Zhu, J.2    Stone, J.R.3    Povlishock, J.T.4
  • 60
    • 0242412504 scopus 로고    scopus 로고
    • Caspase activation increases betaamyloid generation independently of caspase cleavage of the betaamyloid precursor protein (APP)
    • Tesco G, Koh YH, Tanzi RE (2003) Caspase activation increases betaamyloid generation independently of caspase cleavage of the betaamyloid precursor protein (APP). J Biol Chem 278:46074-46080.
    • (2003) J Biol Chem , vol.278 , pp. 46074-46080
    • Tesco, G.1    Koh, Y.H.2    Tanzi, R.E.3
  • 65
    • 70350455062 scopus 로고    scopus 로고
    • The beta-secretase enzyme BACE in health and Alzheimer's disease: Regulation, cell biology, function, and therapeutic potential
    • Vassar R, Kovacs DM, Yan R, Wong PC (2009) The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential. J Neurosci 29:12787-12794.
    • (2009) J Neurosci , vol.29 , pp. 12787-12794
    • Vassar, R.1    Kovacs, D.M.2    Yan, R.3    Wong, P.C.4
  • 66
    • 28044458281 scopus 로고    scopus 로고
    • Energy inhibition elevates β-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: Possible early events in Alzheimer's disease pathogenesis
    • Velliquette RA, O'Connor T, Vassar R (2005) Energy inhibition elevates β-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis. J Neurosci 25:10874-10883.
    • (2005) J Neurosci , vol.25 , pp. 10874-10883
    • Velliquette, R.A.1    O'Connor, T.2    Vassar, R.3
  • 68
    • 20444377260 scopus 로고    scopus 로고
    • GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network
    • Wahle T, Prager K, Raffler N, Haass C, Famulok M, Walter J (2005) GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network. Mol Cell Neurosci 29:453-461.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 453-461
    • Wahle, T.1    Prager, K.2    Raffler, N.3    Haass, C.4    Famulok, M.5    Walter, J.6
  • 70
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G, Huang Q, Rigoutsos I, Nelson PT (2008) The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28:1213-1223.
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5    Huang, Q.6    Rigoutsos, I.7    Nelson, P.T.8
  • 72
    • 0034666112 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury
    • Wang X, Jung J, Asahi M, Chwang W, Russo L, Moskowitz MA, Dixon CE, Fini ME, Lo EH (2000) Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury. J Neurosci 20:7037-7042.
    • (2000) J Neurosci , vol.20 , pp. 7037-7042
    • Wang, X.1    Jung, J.2    Asahi, M.3    Chwang, W.4    Russo, L.5    Moskowitz, M.A.6    Dixon, C.E.7    Fini, M.E.8    Lo, E.H.9
  • 73
    • 2142815707 scopus 로고    scopus 로고
    • Increased betasecretase activity and expression in rats following transient cerebral ischemia
    • Wen Y, Onyewuchi O, Yang S, Liu R, Simpkins JW (2004) Increased betasecretase activity and expression in rats following transient cerebral ischemia. Brain Res 1009:1-8.
    • (2004) Brain Res , vol.1009 , pp. 1-8
    • Wen, Y.1    Onyewuchi, O.2    Yang, S.3    Liu, R.4    Simpkins, J.W.5
  • 76
    • 79958754195 scopus 로고    scopus 로고
    • Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats
    • Zhao JB, Zhang Y, Li GZ, Su XF, Hang CH (2011) Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats. Neurosci Lett 498:147-152.
    • (2011) Neurosci Lett , vol.498 , pp. 147-152
    • Zhao, J.B.1    Zhang, Y.2    Li, G.Z.3    Su, X.F.4    Hang, C.H.5
  • 77
    • 33646244775 scopus 로고    scopus 로고
    • Leaky scanning and reinitiation regulate BACE1 gene expression
    • Zhou W, Song W (2006) Leaky scanning and reinitiation regulate BACE1 gene expression. Mol Cell Biol 26:3353-3364.
    • (2006) Mol Cell Biol , vol.26 , pp. 3353-3364
    • Zhou, W.1    Song, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.