-
1
-
-
0029107952
-
Modification of membrane permeability by animal viruses
-
Carrasco, L. Modification of membrane permeability by animal viruses. Adv. Virus Res. 45, 61-112 (1995).
-
(1995)
Adv. Virus Res.
, vol.45
, pp. 61-112
-
-
Carrasco, L.1
-
3
-
-
3042839154
-
Vpu: A multifunctional protein that enhances the pathogenesis of human immunodeficiency virus type 1
-
Hout, D. R. et al. Vpu: A multifunctional protein that enhances the pathogenesis of human immunodeficiency virus type 1. Curr. HIV Res. 2, 255-270 (2004).
-
(2004)
Curr. HIV Res.
, vol.2
, pp. 255-270
-
-
Hout, D.R.1
-
4
-
-
69149084106
-
Plugging the holes in hepatitis C virus antiviral therapy
-
Griffin, S. D. Plugging the holes in hepatitis C virus antiviral therapy. Proc. Natl Acad. Sci. USA 106, 12567-12568 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 12567-12568
-
-
Griffin, S.D.1
-
5
-
-
79551687044
-
Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
-
Wang, J., Qiu, J. X., Soto, C. & DeGrado, W. F. Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus. Curr. Opin. Struct. Biol. 21, 68-80 (2011).
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 68-80
-
-
Wang, J.1
Qiu, J.X.2
Soto, C.3
Degrado, W.F.4
-
6
-
-
78650280529
-
Viral channel forming proteins-modeling the target
-
Fischer, W. B. & Hsu, H. J. Viral channel forming proteins-modeling the target. Biochim. Biophys. Acta 1808, 561-571 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 561-571
-
-
Fischer, W.B.1
Hsu, H.J.2
-
7
-
-
0018273255
-
Membrane leakiness after viral infection and a new approach to the development of antiviral agents
-
Carrasco, L. Membrane leakiness after viral infection and a new approach to the development of antiviral agents. Nature 272, 694-699 (1978).
-
(1978)
Nature
, vol.272
, pp. 694-699
-
-
Carrasco, L.1
-
8
-
-
0017102950
-
Sodium ions and the shut-off of host cell protein synthesis by picornaviruses
-
Carrasco, L. & Smith, A. E. Sodium ions and the shut-off of host cell protein synthesis by picornaviruses. Nature 264, 807-809 (1976).
-
(1976)
Nature
, vol.264
, pp. 807-809
-
-
Carrasco, L.1
Smith, A.E.2
-
9
-
-
0026710691
-
Expression of poliovirus nonstructural proteins in Escherichia coli cells. Modification of membrane permeability induced by 2B and 3A
-
Lama, J. & Carrasco, L. Expression of poliovirus nonstructural proteins in Escherichia coli cells. Modification of membrane permeability induced by 2B and 3A. J. Biol. Chem. 267, 15932-15937 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15932-15937
-
-
Lama, J.1
Carrasco, L.2
-
10
-
-
0028918959
-
Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A
-
Doedens, J. R. & Kirkegaard, K. Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14, 894-907 (1995).
-
(1995)
EMBO J
, vol.14
, pp. 894-907
-
-
Doedens, J.R.1
Kirkegaard, K.2
-
11
-
-
0029814801
-
Membrane permeabilization by poliovirus proteins 2B and 2BC
-
Aldabe, R., Barco, A. & Carrasco, L. Membrane permeabilization by poliovirus proteins 2B and 2BC. J. Biol. Chem. 271, 23134-23137 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23134-23137
-
-
Aldabe, R.1
Barco, A.2
Carrasco, L.3
-
12
-
-
0030834131
-
Poliovirus protein 2BC increases cytosolic free calcium concentrations
-
Aldabe, R., Irurzun, A. & Carrasco, L. Poliovirus protein 2BC increases cytosolic free calcium concentrations. J. Virol. 71, 6214-6217 (1997).
-
(1997)
J. Virol.
, vol.71
, pp. 6214-6217
-
-
Aldabe, R.1
Irurzun, A.2
Carrasco, L.3
-
13
-
-
0030928285
-
Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release
-
van Kuppeveld, F. J. et al. Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release. EMBO J. 16, 3519-3532 (1997).
-
(1997)
EMBO J
, vol.16
, pp. 3519-3532
-
-
Van Kuppeveld, F.J.1
-
14
-
-
0029036230
-
A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae
-
Barco, A. & Carrasco, L. A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae. EMBO J. 14, 3349-3364 (1995).
-
(1995)
EMBO J
, vol.14
, pp. 3349-3364
-
-
Barco, A.1
Carrasco, L.2
-
15
-
-
0026612385
-
Influenza virus M2 protein has ion channel activity
-
Pinto, L. H., Holsinger, L. J. & Lamb, R. A. Influenza virus M2 protein has ion channel activity. Cell 69, 517-528 (1992).
-
(1992)
Cell
, vol.69
, pp. 517-528
-
-
Pinto, L.H.1
Holsinger, L.J.2
Lamb, R.A.3
-
16
-
-
0029929748
-
The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus
-
Sakaguchi, T., Leser, G. P. & Lamb, R. A. The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus. J. Cell Biol. 133, 733-747 (1996).
-
(1996)
J. Cell Biol.
, vol.133
, pp. 733-747
-
-
Sakaguchi, T.1
Leser, G.P.2
Lamb, R.A.3
-
17
-
-
33646932780
-
The M2 proton channels of influenza A and B viruses
-
Pinto, L. H. & Lamb, R. A. The M2 proton channels of influenza A and B viruses. J. Biol. Chem. 281, 8997-9000 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 8997-9000
-
-
Pinto, L.H.1
Lamb, R.A.2
-
19
-
-
0347928844
-
Alphavirus 6K proteins form ion channels
-
Melton, J. V. et al. Alphavirus 6K proteins form ion channels. J. Biol. Chem. 277, 46923-46931 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46923-46931
-
-
Melton, J.V.1
-
20
-
-
0037449736
-
Interfacial domains in Sindbis virus 6K protein. Detection and functional characterization
-
Sanz, M. A., Madan, V., Carrasco, L. & Nieva, J. L. Interfacial domains in Sindbis virus 6K protein. Detection and functional characterization. J. Biol. Chem. 278, 2051-2057 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2051-2057
-
-
Sanz, M.A.1
Madan, V.2
Carrasco, L.3
Nieva, J.L.4
-
21
-
-
84904244245
-
-
(ed. Fischer, W.) Kluwer Academic/Plenum Publishers
-
Sanz, M. A., Madan, V., Nieva, J. L. & Carrasco, L. in Viral Membrane Proteins: Structure, Function, and Drug Design (ed. Fischer, W.) 233-244 (Kluwer Academic/Plenum Publishers, 2005).
-
(2005)
Viral Membrane Proteins: Structure, Function, and Drug Design
, pp. 233-244
-
-
Sanz, M.A.1
Madan, V.2
Nieva, J.L.3
Carrasco, L.4
-
22
-
-
0141645622
-
Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV 1
-
Park, S. H. et al. Three-dimensional structure of the channel-forming trans-membrane domain of virus protein "u" (Vpu) from HIV 1. J. Mol. Biol. 333, 409-424 (2003).
-
(2003)
J. Mol. Biol.
, vol.333
, pp. 409-424
-
-
Park, S.H.1
-
23
-
-
38549095979
-
Tetherin inhibits retrovirus release and is antagonized by HIV 1 Vpu
-
Neil, S. J., Zang, T. & Bieniasz, P. D. Tetherin inhibits retrovirus release and is antagonized by HIV 1 Vpu. Nature 451, 425-430 (2008).
-
(2008)
Nature
, vol.451
, pp. 425-430
-
-
Neil, S.J.1
Zang, T.2
Bieniasz, P.D.3
-
24
-
-
0037472806
-
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug Amantadine
-
Griffin, S. D. et al. The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine. FEBS Lett. 535, 34-38 (2003).
-
(2003)
FEBS Lett
, vol.535
, pp. 34-38
-
-
Griffin, S.D.1
-
25
-
-
0038284830
-
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives
-
Pavlovic, D. et al. The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives. Proc. Natl Acad. Sci. USA 100, 6104-6108 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6104-6108
-
-
Pavlovic, D.1
-
26
-
-
34547734952
-
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
-
Jones, C. T., Murray, C. L., Eastman, D. K., Tassello, J. & Rice, C. M. Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. J. Virol. 81, 8374-8383 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 8374-8383
-
-
Jones, C.T.1
Murray, C.L.2
Eastman, D.K.3
Tassello, J.4
Rice, C.M.5
-
27
-
-
34547616693
-
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions
-
Steinmann, E. et al. Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions. PLoS Pathog. 3, 962-971 (2007).
-
(2007)
PLoS Pathog
, vol.3
, pp. 962-971
-
-
Steinmann, E.1
-
28
-
-
34548297405
-
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus
-
Steinmann, E. et al. Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus. Hepatology 46, 330-338 (2007).
-
(2007)
Hepatology
, vol.46
, pp. 330-338
-
-
Steinmann, E.1
-
29
-
-
69149090877
-
The 3 dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy
-
Luik, P. et al. The 3 dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy. Proc. Natl Acad. Sci. USA 106, 12712-12716 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 12712-12716
-
-
Luik, P.1
-
30
-
-
41849116366
-
The interferon-induced protein BST 2 restricts HIV 1 release and is downregulated from the cell surface by the viral Vpu protein
-
Van Damme, N. et al. The interferon-induced protein BST 2 restricts HIV 1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 3, 245-252 (2008).
-
(2008)
Cell Host Microbe
, vol.3
, pp. 245-252
-
-
Van Damme, N.1
-
31
-
-
76249125649
-
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
-
Cady, S. D. et al. Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature 463, 689-692 (2010).
-
(2010)
Nature
, vol.463
, pp. 689-692
-
-
Cady, S.D.1
-
32
-
-
78149341400
-
Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production
-
Wozniak, A. L. et al. Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production. PLoS Pathog. 6, e1001087 (2010).
-
(2010)
PLoS Pathog
, vol.6
-
-
Wozniak, A.L.1
-
33
-
-
0036520341
-
Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV 1 protein Vpu
-
Ewart, G. D., Mills, K., Cox, G. B. & Gage, P. W. Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV 1 protein Vpu. Eur. Biophys. J. 31, 26-35 (2002).
-
(2002)
Eur. Biophys. J.
, vol.31
, pp. 26-35
-
-
Ewart, G.D.1
Mills, K.2
Cox, G.B.3
Gage, P.W.4
-
34
-
-
66149104120
-
Influenza A virus lacking M2 protein as a live attenuated vaccine
-
Watanabe, S., Watanabe, T. & Kawaoka, Y. Influenza A virus lacking M2 protein as a live attenuated vaccine. J. Virol. 83, 5947-5950 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 5947-5950
-
-
Watanabe, S.1
Watanabe, T.2
Kawaoka, Y.3
-
35
-
-
78650373530
-
Modulation of HIV 1 host interaction: Role of the Vpu accessory protein
-
Dube, M., Bego, M. G., Paquay, C. & Cohen, E. A. Modulation of HIV 1 host interaction: role of the Vpu accessory protein. Retrovirology 7, 114 (2010).
-
(2010)
Retrovirology
, vol.7
, pp. 114
-
-
Dube, M.1
Bego, M.G.2
Paquay, C.3
Cohen, E.A.4
-
36
-
-
33747617366
-
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release
-
Lu, W. et al. Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release. Proc. Natl Acad. Sci. USA 103, 12540-12545 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 12540-12545
-
-
Lu, W.1
-
37
-
-
0035915994
-
Human immunodeficiency virus type 1 VPU protein affects Sindbis virus glycoprotein processing and enhances membrane permeabilization
-
Gonzalez, M. E. & Carrasco, L. Human immunodeficiency virus type 1 VPU protein affects Sindbis virus glycoprotein processing and enhances membrane permeabilization. Virology 279, 201-209 (2001).
-
(2001)
Virology
, vol.279
, pp. 201-209
-
-
Gonzalez, M.E.1
Carrasco, L.2
-
38
-
-
70350266403
-
Characterization of determinants important for hepatitis C virus p7 function in morphogenesis by using trans-complementation
-
Brohm, C. et al. Characterization of determinants important for hepatitis C virus p7 function in morphogenesis by using trans-complementation. J. Virol. 83, 11682-11693 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 11682-11693
-
-
Brohm, C.1
-
39
-
-
30044437954
-
Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHlVKu1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques
-
Hout, D. R. et al. Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHlVKu1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques. Virology 344, 541-559 (2006).
-
(2006)
Virology
, vol.344
, pp. 541-559
-
-
Hout, D.R.1
-
40
-
-
0038754497
-
-
(eds Semler B. L. & Wimmer E.) American Society for Microbiology Press
-
Carrasco, L., Guinea, R., Irurzun, A. & Barco, A. in Molecular Biology of Picornaviruses (eds Semler, B. L. & Wimmer, E.) 337-354 (American Society for Microbiology Press, 2002).
-
(2002)
Molecular Biology of Picornaviruses
, pp. 337-354
-
-
Carrasco, L.1
Guinea, R.2
Irurzun, A.3
Barco, A.4
-
41
-
-
77957161828
-
Cell permeabilization by poliovirus 2B viroporin triggers bystander permeabilization in neighbouring cells through a mechanism involving gap junctions
-
Madan, V., Redondo, N. & Carrasco, L. Cell permeabilization by poliovirus 2B viroporin triggers bystander permeabilization in neighbouring cells through a mechanism involving gap junctions. Cell. Microbiol. 12, 1144-1157 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 1144-1157
-
-
Madan, V.1
Redondo, N.2
Carrasco, L.3
-
42
-
-
5644221347
-
The NS3 protein of bluetongue virus exhibits viroporin-like properties
-
Han, Z. Y. & Harty, R. N. The NS3 protein of bluetongue virus exhibits viroporin-like properties. J. Biol. Chem. 279, 43092-43097 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43092-43097
-
-
Han, Z.Y.1
Harty, R.N.2
-
43
-
-
12344312935
-
Requirement of the vesicular system for membrane permeabilization by Sindbis virus
-
Madan, V., Sanz, M. A. & Carrasco, L. Requirement of the vesicular system for membrane permeabilization by Sindbis virus. Virology 332, 307-315 (2005).
-
(2005)
Virology
, vol.332
, pp. 307-315
-
-
Madan, V.1
Sanz, M.A.2
Carrasco, L.3
-
44
-
-
35248821836
-
Coronavirus envelope protein: A small membrane protein with multiple functions
-
Liu, D. X., Yuan, Q. & Liao, Y. Coronavirus envelope protein: a small membrane protein with multiple functions. Cell. Mol. Life Sci. 64, 2043-2048 (2007).
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, pp. 2043-2048
-
-
Liu, D.X.1
Yuan, Q.2
Liao, Y.3
-
45
-
-
33947491509
-
Permeabilization of the plasma membrane by Ebola virus GP2
-
Han, Z. Y., Licata, J. M., Paragas, J. & Harty, R. N. Permeabilization of the plasma membrane by Ebola virus GP2. Virus Genes 34, 273-281 (2007).
-
(2007)
Virus Genes
, vol.34
, pp. 273-281
-
-
Han, Z.Y.1
Licata, J.M.2
Paragas, J.3
Harty, R.N.4
-
46
-
-
77950444850
-
The human polyoma JC virus agnoprotein acts as a viroporin
-
Suzuki, T. et al. The human polyoma JC virus agnoprotein acts as a viroporin. PLoS Pathog. 6, e1000801 (2010).
-
(2010)
PLoS Pathog
, vol.6
-
-
Suzuki, T.1
-
47
-
-
0037174990
-
Viroporin-mediated membrane permeabilization. Pore formation by nonstructural poliovirus 2B protein
-
Agirre, A., Barco, A., Carrasco, L. & Nieva, J. L. Viroporin-mediated membrane permeabilization. Pore formation by nonstructural poliovirus 2B protein. J. Biol. Chem. 277, 40434-40441 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40434-40441
-
-
Agirre, A.1
Barco, A.2
Carrasco, L.3
Nieva, J.L.4
-
49
-
-
0030881872
-
A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity
-
Pinto, L. H. et al. A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity. Proc. Natl Acad. Sci. USA 94, 11301-11306 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 11301-11306
-
-
Pinto, L.H.1
-
50
-
-
0030602182
-
Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV 1 infected cells
-
Schubert, U. et al. Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV 1 infected cells. FEBS Lett. 398, 12-18 (1996).
-
(1996)
FEBS Lett
, vol.398
, pp. 12-18
-
-
Schubert, U.1
-
51
-
-
39749180320
-
Biophysical characterization of Vpu from HIV 1 suggests a channel-pore dualism
-
Mehnert, T. et al. Biophysical characterization of Vpu from HIV 1 suggests a channel-pore dualism. Proteins 70, 1488-1497 (2008).
-
(2008)
Proteins
, vol.70
, pp. 1488-1497
-
-
Mehnert, T.1
-
52
-
-
38049161643
-
Viroporins from RNA viruses induce caspase-dependent apoptosis
-
Madan, V., Castello, A. & Carrasco, L. Viroporins from RNA viruses induce caspase-dependent apoptosis. Cell. Microbiol. 10, 437-451 (2008).
-
(2008)
Cell. Microbiol.
, vol.10
, pp. 437-451
-
-
Madan, V.1
Castello, A.2
Carrasco, L.3
-
53
-
-
0042072321
-
The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability
-
Gonzalez, M. E. & Carrasco, L. The human immunodeficiency virus type 1 Vpu protein enhances membrane permeability. Biochemistry 37, 13710-13719 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 13710-13719
-
-
Gonzalez, M.E.1
Carrasco, L.2
-
54
-
-
33846005485
-
Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro
-
Clarke, D. et al. Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro. J. Biol. Chem. 281, 37057-37068 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 37057-37068
-
-
Clarke, D.1
-
55
-
-
21244447668
-
Viroporin activity of murine hepatitis virus e protein
-
Madan, V., Garcia Mde, J., Sanz, M. A. & Carrasco, L. Viroporin activity of murine hepatitis virus E protein. FEBS Lett. 579, 3607-3612 (2005).
-
(2005)
FEBS Lett
, vol.579
, pp. 3607-3612
-
-
Madan, V.1
Garcia Mde, J.2
Sanz, M.A.3
Carrasco, L.4
-
56
-
-
7444229230
-
SARS coronavirus e protein forms cation-selective ion channels
-
Wilson, L., McKinlay, C., Gage, P. & Ewart, G. SARS coronavirus E protein forms cation-selective ion channels. Virology 330, 322-331 (2004).
-
(2004)
Virology
, vol.330
, pp. 322-331
-
-
Wilson, L.1
McKinlay, C.2
Gage, P.3
Ewart, G.4
-
57
-
-
66249083118
-
Emerging roles for lipids in shaping membrane-protein function
-
Phillips, R., Ursell, T., Wiggins, P. & Sens, P. Emerging roles for lipids in shaping membrane-protein function. Nature 459, 379-385 (2009).
-
(2009)
Nature
, vol.459
, pp. 379-385
-
-
Phillips, R.1
Ursell, T.2
Wiggins, P.3
Sens, P.4
-
58
-
-
0041355327
-
Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein
-
Chami, M., Ferrari, D., Nicotera, P., Paterlini-Brechot, P. & Rizzuto, R. Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein. J. Biol. Chem. 278, 31745-31755 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31745-31755
-
-
Chami, M.1
Ferrari, D.2
Nicotera, P.3
Paterlini-Brechot, P.4
Rizzuto, R.5
-
59
-
-
41149092135
-
Functional analysis of picornavirus 2B proteins: Effects on calcium homeostasis and intracellular protein trafficking
-
de Jong, A. S. et al. Functional analysis of picornavirus 2B proteins: effects on calcium homeostasis and intracellular protein trafficking. J. Virol. 82, 3782-3790 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 3782-3790
-
-
De Jong, A.S.1
-
60
-
-
79952153954
-
Rotavirus disrupts calcium homeostasis by NSP4 viroporin activity
-
Hyser, J. M., Collinson-Pautz, M. R., Utama, B. & Estes, M. K. Rotavirus disrupts calcium homeostasis by NSP4 viroporin activity. mBio 1, e00265 10 (2010).
-
(2010)
MBio
, vol.1
, Issue.10
-
-
Hyser, J.M.1
Collinson-Pautz, M.R.2
Utama, B.3
Estes, M.K.4
-
61
-
-
84863988730
-
-
(eds Ehrenfeld E. Domingo E. & Roos R. P.) American Society for Microbiology Press
-
van Kuppeveld, F. J., Below, G. & Ehrenfeld, E. in The Picornaviruses (eds Ehrenfeld, E., Domingo, E. & Roos, R. P.) 181-193 (American Society for Microbiology Press, 2010).
-
(2010)
The Picornaviruses
, pp. 181-193
-
-
Van Kuppeveld, F.J.1
Below, G.2
Ehrenfeld, E.3
-
62
-
-
55549127168
-
Expression of nonstructural rotavirus protein NSP4 mimics Ca2+ homeostasis changes induced by rotavirus infection in cultured cells
-
Diaz, Y. et al. Expression of nonstructural rotavirus protein NSP4 mimics Ca2+ homeostasis changes induced by rotavirus infection in cultured cells. J. Virol. 82, 11331-11343 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 11331-11343
-
-
Diaz, Y.1
-
63
-
-
67649119618
-
Viral calciomics: Interplays between Ca2+ and virus
-
Zhou, Y., Frey, T. K. & Yang, J. J. Viral calciomics: interplays between Ca2+ and virus. Cell Calcium 46, 1-17 (2009).
-
(2009)
Cell Calcium
, vol.46
, pp. 1-17
-
-
Zhou, Y.1
Frey, T.K.2
Yang, J.J.3
-
64
-
-
0037427474
-
Calcium signaling and apoptosis
-
Hajnoczky, G., Davies, E. & Madesh, M. Calcium signaling and apoptosis. Biochem. Biophys. Res. Commun. 304, 445-454 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 445-454
-
-
Hajnoczky, G.1
Davies, E.2
Madesh, M.3
-
65
-
-
0034598337
-
The HIV 1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
-
Jacotot, E. et al. The HIV 1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J. Exp. Med. 191, 33-46 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 33-46
-
-
Jacotot, E.1
-
66
-
-
77953280422
-
Viral reorganization of the secretory pathway generates distinct organelles for RNA replication
-
Hsu, N. Y. et al. Viral reorganization of the secretory pathway generates distinct organelles for RNA replication. Cell 141, 799-811 (2010).
-
(2010)
Cell
, vol.141
, pp. 799-811
-
-
Hsu, N.Y.1
-
67
-
-
0033798416
-
Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: An autophagy-like origin for virus-induced vesicles
-
Suhy, D. A., Giddings, T. H. Jr & Kirkegaard, K. Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J. Virol. 74, 8953-8965 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 8953-8965
-
-
Suhy, D.A.1
Giddings Jr., T.H.2
Kirkegaard, K.3
-
68
-
-
33744928427
-
The coxsackievirus 2B protein increases efflux of ions from the endoplasmic reticulum and Golgi, thereby inhibiting protein trafficking through the Golgi
-
de Jong, A. S. et al. The coxsackievirus 2B protein increases efflux of ions from the endoplasmic reticulum and Golgi, thereby inhibiting protein trafficking through the Golgi. J. Biol. Chem. 281, 14144-14150 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14144-14150
-
-
De Jong, A.S.1
-
69
-
-
75649122282
-
Subversion of the cellular autophagy pathway by viruses
-
Kirkegaard, K. Subversion of the cellular autophagy pathway by viruses. Curr. Top. Microbiol. Immunol. 335, 323-333 (2009).
-
(2009)
Curr. Top. Microbiol. Immunol.
, vol.335
, pp. 323-333
-
-
Kirkegaard, K.1
-
70
-
-
77954082342
-
The Vpu protein: New concepts in virus release and CD4 down-modulation
-
Ruiz, A., Guatelli, J. C. & Stephens, E. B. The Vpu protein: new concepts in virus release and CD4 down-modulation. Curr. HIV Res. 8, 240-252 (2010).
-
(2010)
Curr. HIV Res.
, vol.8
, pp. 240-252
-
-
Ruiz, A.1
Guatelli, J.C.2
Stephens, E.B.3
-
71
-
-
81055156009
-
HIV 1 Vpu antagonizes BST 2 by interfering mainly with the trafficking of newly synthesized BST 2 to the cell surface
-
Dube, M. et al. HIV 1 Vpu antagonizes BST 2 by interfering mainly with the trafficking of newly synthesized BST 2 to the cell surface. Traffic 12, 1714-1729 (2011).
-
(2011)
Traffic
, vol.12
, pp. 1714-1729
-
-
Dube, M.1
-
72
-
-
79959211941
-
Host factors involved in retroviral budding and release
-
Martin-Serrano, J. & Neil, S. J. Host factors involved in retroviral budding and release. Nature Rev. Microbiol. 9, 519-531 (2011).
-
(2011)
Nature Rev. Microbiol.
, vol.9
, pp. 519-531
-
-
Martin-Serrano, J.1
Neil, S.J.2
-
73
-
-
0001238550
-
Functional role of human immunodeficiency virus type 1 vpu
-
Terwilliger, E. F., Cohen, E. A., Lu, Y. C., Sodroski, J. G. & Haseltine, W. A. Functional role of human immunodeficiency virus type 1 vpu. Proc. Natl Acad. Sci. USA 86, 5163-5167 (1989).
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 5163-5167
-
-
Terwilliger, E.F.1
Cohen, E.A.2
Lu, Y.C.3
Sodroski, J.G.4
Haseltine, W.A.5
-
74
-
-
33646718791
-
The cytoplasmic tail of the influenza A virus M2 protein plays a role in viral assembly
-
Iwatsuki-Horimoto, K. et al. The cytoplasmic tail of the influenza A virus M2 protein plays a role in viral assembly. J. Virol. 80, 5233-5240 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 5233-5240
-
-
Iwatsuki-Horimoto, K.1
-
75
-
-
77957335251
-
Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV 1 release
-
Hsu, K., Han, J., Shinlapawittayatorn, K., Deschenes, I. & Marban, E. Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV 1 release. Biophys. J. 99, 1718-1725 (2010).
-
(2010)
Biophys. J.
, vol.99
, pp. 1718-1725
-
-
Hsu, K.1
Han, J.2
Shinlapawittayatorn, K.3
Deschenes, I.4
Marban, E.5
-
76
-
-
81155152605
-
Background K2P channels KCNK3/9/15 limit the budding of cell membrane-derived vesicles
-
Huang, D. T., Chi, N., Chen, S. C., Lee, T. Y. & Hsu, K. Background K2P channels KCNK3/9/15 limit the budding of cell membrane-derived vesicles. Cell Biochem. Biophys. 61, 585-594 (2011).
-
(2011)
Cell Biochem. Biophys.
, vol.61
, pp. 585-594
-
-
Huang, D.T.1
Chi, N.2
Chen, S.C.3
Lee, T.Y.4
Hsu, K.5
-
77
-
-
38749106195
-
Structure and mechanism of the M2 proton channel of influenza A virus
-
Schnell, J. R. & Chou, J. J. Structure and mechanism of the M2 proton channel of influenza A virus. Nature 451, 591-595 (2008).
-
(2008)
Nature
, vol.451
, pp. 591-595
-
-
Schnell, J.R.1
Chou, J.J.2
-
78
-
-
77957269747
-
Proton and cation transport activity of the M2 proton channel from influenza A virus
-
Leiding, T., Wang, J., Martinsson, J., DeGrado, W. F. & Arskold, S. P. Proton and cation transport activity of the M2 proton channel from influenza A virus. Proc. Natl Acad. Sci. USA 107, 15409-15414 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15409-15414
-
-
Leiding, T.1
Wang, J.2
Martinsson, J.3
Degrado, W.F.4
Arskold, S.P.5
-
79
-
-
77958156306
-
Insight into the mechanism of the influenza A proton channel from a structure in a lipid bilayer
-
Sharma, M. et al. Insight into the mechanism of the influenza A proton channel from a structure in a lipid bilayer. Science 330, 509-512 (2010).
-
(2010)
Science
, vol.330
, pp. 509-512
-
-
Sharma, M.1
-
80
-
-
77956637693
-
Influenza virus M2 protein mediates ESCRT-independent membrane scission
-
Rossman, J. S., Jing, X., Leser, G. P. & Lamb, R. A. Influenza virus M2 protein mediates ESCRT-independent membrane scission. Cell 142, 902-913 (2010).
-
(2010)
Cell
, vol.142
, pp. 902-913
-
-
Rossman, J.S.1
Jing, X.2
Leser, G.P.3
Lamb, R.A.4
-
81
-
-
0027966106
-
Entry of animal viruses and macromolecules into cells
-
Carrasco, L. Entry of animal viruses and macromolecules into cells. FEBS Lett. 350, 151-154 (1994).
-
(1994)
FEBS Lett
, vol.350
, pp. 151-154
-
-
Carrasco, L.1
-
82
-
-
0035017262
-
Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity
-
Watanabe, T., Watanabe, S., Ito, H., Kida, H. & Kawaoka, Y. Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity. J. Virol. 75, 5656-5662 (2001).
-
(2001)
J. Virol.
, vol.75
, pp. 5656-5662
-
-
Watanabe, T.1
Watanabe, S.2
Ito, H.3
Kida, H.4
Kawaoka, Y.5
-
83
-
-
58149390243
-
Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel
-
Griffin, S. et al. Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel. Hepatology 48, 1779-1790 (2008).
-
(2008)
Hepatology
, vol.48
, pp. 1779-1790
-
-
Griffin, S.1
-
84
-
-
0018858406
-
Viral infection permeabilizes mammalian cells to protein toxins
-
Fernandez-Puentes, C. & Carrasco, L. Viral infection permeabilizes mammalian cells to protein toxins. Cell 20, 769-775 (1980).
-
(1980)
Cell
, vol.20
, pp. 769-775
-
-
Fernandez-Puentes, C.1
Carrasco, L.2
-
85
-
-
0042335650
-
Mechanisms of membrane permeabilization by picornavirus 2B viroporin
-
Nieva, J. L., Agirre, A., Nir, S. & Carrasco, L. Mechanisms of membrane permeabilization by picornavirus 2B viroporin. FEBS Lett. 552, 68-73 (2003).
-
(2003)
FEBS Lett
, vol.552
, pp. 68-73
-
-
Nieva, J.L.1
Agirre, A.2
Nir, S.3
Carrasco, L.4
-
86
-
-
0029951824
-
Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication
-
van Kuppeveld, F. J., Galama, J. M., Zoll, J., van den Hurk, P. J. & Melchers, W. J. Coxsackie B3 virus protein 2B contains cationic amphipathic helix that is required for viral RNA replication. J. Virol. 70, 3876-3886 (1996).
-
(1996)
J. Virol.
, vol.70
, pp. 3876-3886
-
-
Van Kuppeveld, F.J.1
Galama, J.M.2
Zoll, J.3
Van Den Hurk, P.J.4
Melchers, W.J.5
-
87
-
-
0031555654
-
Structure-function analysis of coxsackie B3 virus protein 2B
-
van Kuppeveld, F. J., Melchers, W. J., Kirkegaard, K. & Doedens, J. R. Structure-function analysis of coxsackie B3 virus protein 2B. Virology 227, 111-118 (1997).
-
(1997)
Virology
, vol.227
, pp. 111-118
-
-
Van Kuppeveld, F.J.1
Melchers, W.J.2
Kirkegaard, K.3
Doedens, J.R.4
-
88
-
-
80055112699
-
Membrane integration of poliovirus 2B viroporin
-
Martinez-Gil, L. et al. Membrane integration of poliovirus 2B viroporin. J. Virol. 85, 11315-11324 (2011).
-
(2011)
J. Virol.
, vol.85
, pp. 11315-11324
-
-
Martinez-Gil, L.1
-
89
-
-
0031968980
-
Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity
-
Barco, A. & Carrasco, L. Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity. J. Virol. 72, 3560-3570 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 3560-3570
-
-
Barco, A.1
Carrasco, L.2
-
90
-
-
0037428390
-
Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle
-
de Jong, A. S. et al. Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle. J. Biol. Chem. 278, 1012-1021 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1012-1021
-
-
De Jong, A.S.1
-
91
-
-
0036721022
-
Homomultimerization of the coxsackievirus 2B protein in living cells visualized by fluorescence resonance energy transfer microscopy
-
van Kuppeveld, F. J., Melchers, W. J., Willems, P. H. & Gadella, T. W. Jr. Homomultimerization of the coxsackievirus 2B protein in living cells visualized by fluorescence resonance energy transfer microscopy. J. Virol. 76, 9446-9456 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 9446-9456
-
-
Van Kuppeveld, F.J.1
Melchers, W.J.2
Willems, P.H.3
Gadella Jr., T.W.4
-
92
-
-
71849098810
-
Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses
-
Patargias, G., Barke, T., Watts, A. & Fischer, W. B. Model generation of viral channel forming 2B protein bundles from polio and coxsackie viruses. Mol. Membr. Biol. 26, 309-320 (2009).
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 309-320
-
-
Patargias, G.1
Barke, T.2
Watts, A.3
Fischer, W.B.4
-
93
-
-
0025761657
-
Cytolytic pore-forming proteins and peptides: Is there a common structural motif?
-
Ojcius, D. M. & Young, J. D. Cytolytic pore-forming proteins and peptides: is there a common structural motif? Trends Biochem. Sci. 16, 225-229 (1991).
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 225-229
-
-
Ojcius, D.M.1
Young, J.D.2
-
94
-
-
35948993002
-
Plasma membrane-porating domain in poliovirus 2B protein. A short peptide mimics viroporin activity
-
Madan, V. et al. Plasma membrane-porating domain in poliovirus 2B protein. A short peptide mimics viroporin activity. J. Mol. Biol. 374, 951-964 (2007).
-
(2007)
J. Mol. Biol.
, vol.374
, pp. 951-964
-
-
Madan, V.1
-
95
-
-
53249103315
-
Functional and structural characterization of 2B viroporin membranolytic domains
-
Sanchez-Martinez, S. et al. Functional and structural characterization of 2B viroporin membranolytic domains. Biochemistry 47, 10731-10739 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 10731-10739
-
-
Sanchez-Martinez, S.1
-
96
-
-
0036828783
-
Course and outcome of hepatitis C
-
Hoofnagle, J. H. Course and outcome of hepatitis C. Hepatology 36, S21-S29 (2002).
-
(2002)
Hepatology
, vol.36
-
-
Hoofnagle, J.H.1
-
97
-
-
34249024924
-
Replication of hepatitis C virus
-
Moradpour, D., Penin, F. & Rice, C. M. Replication of hepatitis C virus. Nature Rev. Microbiol. 5, 453-463 (2007).
-
(2007)
Nature Rev. Microbiol.
, vol.5
, pp. 453-463
-
-
Moradpour, D.1
Penin, F.2
Rice, C.M.3
-
98
-
-
79952131523
-
Hepatitis C virus P7 - A viroporin crucial for virus assembly and an emerging target for antiviral therapy
-
Steinmann, E. & Pietschmann, T. Hepatitis C virus P7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy. Viruses 2, 2078-2095 (2010).
-
(2010)
Viruses
, vol.2
, pp. 2078-2095
-
-
Steinmann, E.1
Pietschmann, T.2
-
99
-
-
1642450632
-
Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride
-
Premkumar, A., Wilson, L., Ewart, G. D. & Gage, P. W. Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride. FEBS Lett. 557, 99-103 (2004).
-
(2004)
FEBS Lett
, vol.557
, pp. 99-103
-
-
Premkumar, A.1
Wilson, L.2
Ewart, G.D.3
Gage, P.W.4
-
100
-
-
77957789317
-
NMR structure and ion channel activity of the p7 protein from hepatitis C virus
-
Montserret, R. et al. NMR structure and ion channel activity of the p7 protein from hepatitis C virus. J. Biol. Chem. 285, 31446-31461 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 31446-31461
-
-
Montserret, R.1
-
101
-
-
14744276061
-
The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging
-
McCown, M. F. & Pekosz, A. The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging. J. Virol. 79, 3595-3605 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 3595-3605
-
-
McCown, M.F.1
Pekosz, A.2
-
102
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellular M2 ion channel
-
Ichinohe, T., Pang, I. K. & Iwasaki, A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nature Immunol. 11, 404-410 (2010).
-
(2010)
Nature Immunol.
, vol.11
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
103
-
-
84863158307
-
Human annexin A6 interacts with influenza A virus protein M2 and negatively modulates infection
-
Ma, H. et al. Human annexin A6 interacts with influenza A virus protein M2 and negatively modulates infection J. Virol. 86, 1789-1901 (2012).
-
(2012)
J. Virol
, vol.86
, pp. 1789-1901
-
-
Ma, H.1
-
104
-
-
72649105081
-
Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes
-
Gannage, M. et al. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 6, 367-380 (2009).
-
(2009)
Cell Host Microbe
, vol.6
, pp. 367-380
-
-
Gannage, M.1
-
105
-
-
0037062579
-
Bundles consisting of extended transmembrane segments of Vpu from HIV 1: Computer simulations and conductance measurements
-
Cordes, F. S., Tustian, A. D., Sansom, M. S., Watts, A. & Fischer, W. B. Bundles consisting of extended transmembrane segments of Vpu from HIV 1: computer simulations and conductance measurements. Biochemistry 41, 7359-7365 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 7359-7365
-
-
Cordes, F.S.1
Tustian, A.D.2
Sansom, M.S.3
Watts, A.4
Fischer, W.B.5
-
106
-
-
84861209115
-
Cytoplasmic tail determinant in HIV 1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction
-
Kueck, T. & Neil, S. J. A. Cytoplasmic tail determinant in HIV 1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. PLoS Pathog. 8, e1002609 (2011).
-
(2011)
PLoS Pathog
, vol.8
-
-
Kueck, T.1
Neil, S.J.A.2
-
107
-
-
84856946718
-
Transmembrane domain determinants of CD4 downregulation by HIV 1 Vpu
-
Magadan, J. G. & Bonifacino, J. S. Transmembrane domain determinants of CD4 downregulation by HIV 1 Vpu. J. Virol. 86, 757-772 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 757-772
-
-
Magadan, J.G.1
Bonifacino, J.S.2
-
108
-
-
71749086904
-
HIV 1 accessory protein Vpu internalizes cell-surface BST 2/tetherin through transmembrane interactions leading to lysosomes
-
Iwabu, Y. et al. HIV 1 accessory protein Vpu internalizes cell-surface BST 2/tetherin through transmembrane interactions leading to lysosomes. J. Biol. Chem. 284, 35060-35072 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35060-35072
-
-
Iwabu, Y.1
-
109
-
-
70350348675
-
Tetherin inhibits HIV 1 release by directly tethering virions to cells
-
Perez-Caballero, D. et al. Tetherin inhibits HIV 1 release by directly tethering virions to cells. Cell 139, 499-511 (2009).
-
(2009)
Cell
, vol.139
, pp. 499-511
-
-
Perez-Caballero, D.1
-
110
-
-
77956188831
-
BST 2/tetherin: A new component of the innate immune response to enveloped viruses
-
Evans, D. T., Serra-Moreno, R., Singh, R. K. & Guatelli, J. C. BST 2/tetherin: a new component of the innate immune response to enveloped viruses. Trends Microbiol. 18, 388-396 (2010).
-
(2010)
Trends Microbiol
, vol.18
, pp. 388-396
-
-
Evans, D.T.1
Serra-Moreno, R.2
Singh, R.K.3
Guatelli, J.C.4
-
111
-
-
34548392739
-
An interferon-alpha-induced tethering mechanism inhibits HIV 1 and Ebola virus particle release but is counteracted by the HIV 1 Vpu protein
-
Neil, S. J., Sandrin, V., Sundquist, W. I. & Bieniasz, P. D. An interferon-alpha-induced tethering mechanism inhibits HIV 1 and Ebola virus particle release but is counteracted by the HIV 1 Vpu protein. Cell Host Microbe 2, 193-203 (2007).
-
(2007)
Cell Host Microbe
, vol.2
, pp. 193-203
-
-
Neil, S.J.1
Sandrin, V.2
Sundquist, W.I.3
Bieniasz, P.D.4
-
112
-
-
77956996035
-
Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus
-
Acharya, R. et al. Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus. Proc. Natl Acad. Sci. USA 107, 15075-15080 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15075-15080
-
-
Acharya, R.1
-
113
-
-
38349070736
-
Proton transport through influenza A virus M2 protein reconstituted in vesicles
-
Moffat, J. C. et al. Proton transport through influenza A virus M2 protein reconstituted in vesicles. Biophys. J. 94, 434-445 (2008).
-
(2008)
Biophys. J.
, vol.94
, pp. 434-445
-
-
Moffat, J.C.1
-
114
-
-
38749151911
-
Structural basis for the function and inhibition of an influenza virus proton channel
-
Stouffer, A. L. et al. Structural basis for the function and inhibition of an influenza virus proton channel. Nature 451, 596-599 (2008).
-
(2008)
Nature
, vol.451
, pp. 596-599
-
-
Stouffer, A.L.1
-
115
-
-
77957299044
-
Oligomerization state and supramolecular structure of the HIV 1 Vpu protein transmembrane segment in phospholipid bilayers
-
Lu, J. X., Sharpe, S., Ghirlando, R., Yau, W. M. & Tycko, R. Oligomerization state and supramolecular structure of the HIV 1 Vpu protein transmembrane segment in phospholipid bilayers. Protein Sci. 19, 1877-1896 (2010).
-
(2010)
Protein Sci
, vol.19
, pp. 1877-1896
-
-
Lu, J.X.1
Sharpe, S.2
Ghirlando, R.3
Yau, W.M.4
Tycko, R.5
-
116
-
-
0036708437
-
Molecular dynamics investigation of membrane-bound bundles of the channel-forming transmembrane domain of viral protein U from the human immunodeficiency virus HIV 1
-
Lopez, C. F., Montal, M., Blasie, J. K., Klein, M. L. & Moore, P. B. Molecular dynamics investigation of membrane-bound bundles of the channel-forming transmembrane domain of viral protein U from the human immunodeficiency virus HIV 1. Biophys. J. 83, 1259-1267 (2002).
-
(2002)
Biophys. J.
, vol.83
, pp. 1259-1267
-
-
Lopez, C.F.1
Montal, M.2
Blasie, J.K.3
Klein, M.L.4
Moore, P.B.5
-
117
-
-
79954824393
-
Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy
-
Cook, G. A. & Opella, S. J. Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy. Biochim. Biophys. Acta 1808, 1448-1453 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 1448-1453
-
-
Cook, G.A.1
Opella, S.J.2
-
118
-
-
0025988125
-
Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses
-
Kendal, A. P. & Klenk, H. D. Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses. Arch. Virol. 119, 265-273 (1991).
-
(1991)
Arch. Virol.
, vol.119
, pp. 265-273
-
-
Kendal, A.P.1
Klenk, H.D.2
-
119
-
-
34547418131
-
Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system
-
StGelais, C. et al. Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system. Antiviral Res. 76, 48-58 (2007).
-
(2007)
Antiviral Res
, vol.76
, pp. 48-58
-
-
Stgelais, C.1
-
120
-
-
79251559935
-
Combination chemotherapy for influenza
-
Govorkova, E. A. & Webster, R. G. Combination chemotherapy for influenza. Viruses 2, 1510-1529 (2010).
-
(2010)
Viruses
, vol.2
, pp. 1510-1529
-
-
Govorkova, E.A.1
Webster, R.G.2
-
121
-
-
79959569817
-
Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel
-
Foster, T. L. et al. Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel. Hepatology 54, 79-90 (2011).
-
(2011)
Hepatology
, vol.54
, pp. 79-90
-
-
Foster, T.L.1
-
122
-
-
77955554384
-
No beneficial effects of amantadine in treatment of chronic hepatitis C patients
-
van Soest, H. et al. No beneficial effects of amantadine in treatment of chronic hepatitis C patients. Dig. Liver Dis. 42, 496-502 (2010).
-
(2010)
Dig. Liver Dis.
, vol.42
, pp. 496-502
-
-
Van Soest, H.1
-
123
-
-
34247895578
-
The hepatitis C virus life cycle as a target for new antiviral therapies
-
Pawlotsky, J. M., Chevaliez, S. & McHutchison, J. G. The hepatitis C virus life cycle as a target for new antiviral therapies. Gastroenterology 132, 1979-1998 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 1979-1998
-
-
Pawlotsky, J.M.1
Chevaliez, S.2
McHutchison, J.G.3
-
124
-
-
33748714028
-
Hexamethylene amiloride blocks e protein ion channels and inhibits coronavirus replication
-
Wilson, L., Gage, P. & Ewart, G. Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication. Virology 353, 294-306 (2006).
-
(2006)
Virology
, vol.353
, pp. 294-306
-
-
Wilson, L.1
Gage, P.2
Ewart, G.3
-
125
-
-
77951296857
-
A novel Hepatitis C virus p7 ion channel inhibitor, BIT225, inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interferon-α 2b and nucleoside analogues
-
Luscombe, C. A. et al. A novel Hepatitis C virus p7 ion channel inhibitor, BIT225, inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interferon-α 2b and nucleoside analogues. Antiviral Res. 86, 144-153 (2010).
-
(2010)
Antiviral Res
, vol.86
, pp. 144-153
-
-
Luscombe, C.A.1
-
126
-
-
75749156935
-
Antiviral efficacy of the novel compound BIT225 against HIV 1 release from human macrophages
-
Khoury, G., Ewart, G., Luscombe, C., Miller, M. & Wilkinson, J. Antiviral efficacy of the novel compound BIT225 against HIV 1 release from human macrophages. Antimicrob. Agents Chemother. 54, 835-845 (2010).
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 835-845
-
-
Khoury, G.1
Ewart, G.2
Luscombe, C.3
Miller, M.4
Wilkinson, J.5
-
127
-
-
79961207692
-
DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71
-
Xie, S. Q. et al. DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71. Cell Res. 21, 1271-1275 (2011).
-
(2011)
Cell Res
, vol.21
, pp. 1271-1275
-
-
Xie, S.Q.1
-
128
-
-
79954611840
-
Development and validation of a high-throughput screening assay for the hepatitis C virus p7 viroporin
-
Gervais, C. et al. Development and validation of a high-throughput screening assay for the hepatitis C virus p7 viroporin. J. Biomol. Screen 16, 363-369 (2011).
-
(2011)
J. Biomol. Screen
, vol.16
, pp. 363-369
-
-
Gervais, C.1
-
129
-
-
79959832190
-
The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release
-
Raghava, S., Giorda, K. M., Romano, F. B., Heuck, A. P. & Hebert, D. N. The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release. PLoS Pathog. 7, e1002116 (2011).
-
(2011)
PLoS Pathog
, vol.7
-
-
Raghava, S.1
Giorda, K.M.2
Romano, F.B.3
Heuck, A.P.4
Hebert, D.N.5
-
130
-
-
84861326301
-
High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors
-
Wetherill, L. F. et al. High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors. J. Virol. 86, 5341-5351 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 5341-5351
-
-
Wetherill, L.F.1
-
131
-
-
84934437445
-
The transmembrane domain of the infectious bronchitis virus e protein is required for efficient virus release
-
Machamer, C. E. & Youn, S. The transmembrane domain of the infectious bronchitis virus E protein is required for efficient virus release. Adv. Exp. Med. Biol. 581, 193-198 (2006).
-
(2006)
Adv. Exp. Med. Biol.
, vol.581
, pp. 193-198
-
-
MacHamer, C.E.1
Youn, S.2
-
132
-
-
33947419673
-
Role of the coronavirus e viroporin protein transmembrane domain in virus assembly
-
Ye, Y. & Hogue, B. G. Role of the coronavirus E viroporin protein transmembrane domain in virus assembly. J. Virol. 81, 3597-3607 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 3597-3607
-
-
Ye, Y.1
Hogue, B.G.2
-
133
-
-
34848924369
-
Regulation of cell death during infection by the severe acute respiratory syndrome coronavirus and other coronaviruses
-
Tan, Y. J., Lim, S. G. & Hong, W. Regulation of cell death during infection by the severe acute respiratory syndrome coronavirus and other coronaviruses. Cell. Microbiol. 9, 2552-2561 (2007).
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 2552-2561
-
-
Tan, Y.J.1
Lim, S.G.2
Hong, W.3
-
134
-
-
0034008733
-
A potassium channel protein encoded by chlorella virus PBCV 1
-
Plugge, B. et al. A potassium channel protein encoded by chlorella virus PBCV 1. Science 287, 1641-1644 (2000).
-
(2000)
Science
, vol.287
, pp. 1641-1644
-
-
Plugge, B.1
-
135
-
-
78650261371
-
Viral proteins function as ion channels
-
Wang, K., Xie, S. Q. & Sun, B. Viral proteins function as ion channels. Biochim. Biophys. Acta 1808, 510-515 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 510-515
-
-
Wang, K.1
Xie, S.Q.2
Sun, B.3
-
136
-
-
84863986411
-
Classical swine fever virus p7 protein is a viroporin involved in virulence in swine
-
Gladue, D. P. et al. Classical swine fever virus p7 protein is a viroporin involved in virulence in swine. J. Virol. 86, 6778-6791 (2012).
-
(2012)
J. Virol.
, vol.86
, pp. 6778-6791
-
-
Gladue, D.P.1
-
137
-
-
0038347950
-
Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes
-
Mould, J. A. et al. Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes. Dev. Cell 5, 175-184 (2003).
-
(2003)
Dev. Cell
, vol.5
, pp. 175-184
-
-
Mould, J.A.1
-
138
-
-
9044243753
-
Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers
-
Piller, S. C., Ewart, G. D., Premkumar, A., Cox, G. B. & Gage, P. W. Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers. Proc. Natl Acad. Sci. USA 93, 111-115 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 111-115
-
-
Piller, S.C.1
Ewart, G.D.2
Premkumar, A.3
Cox, G.B.4
Gage, P.W.5
-
139
-
-
77952673390
-
Effects of human T cell leukemia virus type 1 (HTLV 1) p13 on mitochondrial K+ permeability: A new member of the viroporin family?
-
Silic-Benussi, M., Marin, O., Biasiotto, R., D'Agostino, D. M. & Ciminale, V. Effects of human T cell leukemia virus type 1 (HTLV 1) p13 on mitochondrial K+ permeability: a new member of the viroporin family? FEBS Lett. 584, 2070-2075 (2010).
-
(2010)
FEBS Lett
, vol.584
, pp. 2070-2075
-
-
Silic-Benussi, M.1
Marin, O.2
Biasiotto, R.3
D'Agostino, D.M.4
Ciminale, V.5
|