Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy

Biochimica et Biophysica Acta - Biomembranes

Volumn 1808, Issue 6, 2011, Pages 1448-1453

  Cook, Gabriel A ^a   Opella, Stanley J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MC 0307 ^*  (United States)

Author keywords

Hepatitis C virus; Membrane protein; Nuclear magnetic resonance; p7; Secondary structure

Indexed keywords

MEMBRANE PROTEIN; PROTEIN P7; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; HEPATITIS C VIRUS; MICELLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; SOLID STATE;

DEUTERIUM EXCHANGE MEASUREMENT; DEUTERIUM OXIDE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HEPACIVIRUS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHOLIPID ETHERS; PROTEIN STRUCTURE, SECONDARY; VIRAL PROTEINS; WATER;

HEPATITIS C VIRUS;

EID: 79954824393     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.08.010     Document Type: Article

References (37)

1. Q.L. Choo, K.H. Richman, J.H. Han, K. Berger, C. Lee, C. Dong, C. Gallegos, D. Coit, R. Medina-Selby, and P.J. Barr Genetic organization and diversity of the hepatitis C virus Proc Nat Acad Sci U S A 88 1991 2451 2455 (Pubitemid 21916435)
2. J.G. McHutchison, S.C. Gordon, E.R. Schiff, M.L. Shiffman, W.M. Lee, V.K. Rustgi, Z.D. Goodman, M.H. Ling, S. Cort, and J.K. Albrecht Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C Hepatitis Interventional Therapy Group N Engl J Med 339 1998 1485 1492 (Pubitemid 28543496)
3. S.J. Hadziyannis, H. Sette Jr., T.R. Morgan, V. Balan, M. Diago, P. Marcellin, G. Ramadori, H. Bodenheimer Jr., D. Bernstein, M. Rizzetto, S. Zeuzem, P.J. Pockros, A. Lin, and A.M. Ackrill Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose Ann Intern Med 140 2004 346 355
4. A.M. Di Bisceglie, H.S. Conjeevaram, M.W. Fried, R. Sallie, Y. Park, C. Yurdaydin, M. Swain, D.E. Kleiner, K. Mahaney, and J.H. Hoofnagle Ribavirin as therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial Ann Intern Med 123 1995 897 903
5. G.L. Davis, R. Esteban-Mur, V. Rustgi, J. Hoefs, S.C. Gordon, C. Trepo, M.L. Shiffman, S. Zeuzem, A. Craxi, M.H. Ling, and J. Albrecht Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group N Engl J Med 339 1998 1493 1499 (Pubitemid 28543497)
6. M.J. Selby, E. Glazer, F. Masiarz, and M. Houghton Complex processing and protein:protein interactions in the E2:NS2 region of HCV Virology 204 1994 114 122
7. C. Lin, B.D. Lindenbach, B.M. Pragai, D.W. McCourt, and C.M. Rice Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini J Virol 68 1994 5063 5073 (Pubitemid 24226574)
8. M.E. Gonzalez, and L. Carrasco Viroporins FEBS Lett 552 2003 28 34 (Pubitemid 37103005)
9. A. Sakai, M.S. Claire, K. Faulk, S. Govindarajan, S.U. Emerson, R.H. Purcell, and J. Bukh The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences Proc Nat Acad Sci USA 100 2003 11646 11651 (Pubitemid 37205990)
10. T. Harada, N. Tautz, and H.J. Thiel E2-p7 region of the bovine viral diarrhea virus polyprotein: processing and functional studies J Virol 74 2000 9498 9506
11. S. Carrere-Kremer, C. Montpellier-Pala, L. Cocquerel, C. Wychowski, F. Penin, and J. Dubuisson Subcellular localization and topology of the p7 polypeptide of hepatitis C virus J Virol 76 2002 3720 3730 (Pubitemid 34250536)
12. G. Patargias, N. Zitzmann, R. Dwek, and W.B. Fischer Protein-protein interactions: modeling the hepatitis C virus ion channel p7 J Med Chem 49 2006 648 655 (Pubitemid 43157494)
13. S.D. Griffin, L.P. Beales, D.S. Clarke, O. Worsfold, S.D. Evans, J. Jaeger, M.P. Harris, and D.J. Rowlands The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine FEBS Lett 535 2003 34 38 (Pubitemid 36126351)
14. D. Pavlovic, D.C. Neville, O. Argaud, B. Blumberg, R.A. Dwek, W.B. Fischer, and N. Zitzmann The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives Proc Nat Acad Sci USA 100 2003 6104 6108 (Pubitemid 36576938)
15. A. Premkumar, L. Wilson, G.D. Ewart, and P.W. Gage Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride FEBS Lett 557 2004 99 103 (Pubitemid 38115876)
16. P. Luik, C. Chew, J. Aittoniemi, J. Chang, P. Wentworth Jr., R.A. Dwek, P.C. Biggin, C. Venien-Bryan, and N. Zitzmann The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy Proc Nat Acad Sci USA 106 2009 12712 12716
17. N.A. Farrow, R. Muhandiram, A.U. Singer, S.M. Pascal, C.M. Kay, G. Gish, S.E. Shoelson, T. Pawson, J.D. Forman-Kay, and L.E. Kay Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15 N NMR relaxation Biochemistry 33 1994 5984 6003 (Pubitemid 24184605)
18. G. Veglia, A.C. Zeri, C. Ma, and S.J. Opella Deuterium/hydrogen exchange factors measured by solution nuclear magnetic resonance spectroscopy as indicators of the structure and topology of membrane proteins Biophys J 82 2002 2176 2183 (Pubitemid 34280830)
19. T.L. Lau, A.W. Partridge, M.H. Ginsberg, and T.S. Ulmer Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles Biochemistry 47 2008 4008 4016 (Pubitemid 351458115)
20. J. Iwahara, C.D. Schwieters, and G.M. Clore Ensemble approach for NMR structure refinement against (1)H paramagnetic relaxation enhancement data arising from a flexible paramagnetic group attached to a macromolecule J Am Chem Soc 126 2004 5879 5896 (Pubitemid 38621427)
21. R.R. Vold, R.S. Prosser, and A.J. Deese Isotropic solutions of phospholipid bicelles: a new membrane mimetic for high-resolution NMR studies of polypeptides J Biomol NMR 9 1997 329 335 (Pubitemid 127505395)
22. 13C chemical-shift data J Biomol NMR 4 1994 171 180
23. M.F. Mesleh, S. Lee, G. Veglia, D.S. Thiriot, F.M. Marassi, and S.J. Opella Dipolar waves map the structure and topology of helices in membrane proteins J Am Chem Soc 125 2003 8928 8935 (Pubitemid 36886231)
24. M.F. Mesleh, and S.J. Opella Dipolar waves as NMR maps of helices in proteins J Magn Reson 163 2003 288 299
25. M.F. Mesleh, G. Veglia, T.M. DeSilva, F.M. Marassi, and S.J. Opella Dipolar waves as NMR maps of protein structure J Am Chem Soc 124 2002 4206 4207 (Pubitemid 34441543)
26. G.A. Cook, S. Steffer, and S.J. Opella Expression and purification of the membrane protein p7 from HCV Biopolymers Peptide Science 96 2011 32 40
27. R. Estephan, J. Englander, B. Arshava, K.L. Samples, J.M. Becker, and F. Naider Biosynthesis and NMR analysis of a 73-residue domain of a Saccharomyces cerevisiae G protein-coupled receptor Biochemistry 44 2005 11795 11810 (Pubitemid 41262714)
28. G.F. Miozzari, and C. Yanofsky Translation of the leader region of the Escherichia coli tryptophan operon J Bacteriol 133 1978 1457 1466 (Pubitemid 8297007)
29. D.H. Jones, and S.J. Opella Weak alignment of membrane proteins in stressed polyacrylamide gels J Magn Reson 171 2004 258 269
30. Y. Ishii, M.A. Markus, and R. Tycko Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel J Biomol NMR 21 2001 141 151 (Pubitemid 33040162)
31. A.A. De Angelis, and S.J. Opella Bicelle samples for solid-state NMR of membrane proteins Nat Protoc 2 2007 2332 2338
32. S. Mori, C. Abeygunawardana, M.O. Johnson, and P.C. van Zijl Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation J Magn Reson B 108 1995 94 98
33. 15N-enriched proteins J Biomol NMR 3 1993 185 204
34. C.H. Wu, C.V. Grant, G.A. Cook, S.H. Park, and S.J. Opella A strip shield improves the efficiency of a solenoid coil in probes for high field solid-state NMR of lossy biological samples J Magn Reson 200 2009 74 80
35. A.A. Nevzorov, and S.J. Opella A "magic sandwich" pulse sequence with reduced offset dependence for high-resolution separated local field spectroscopy J Magn Reson 164 2003 182 186
36. F. Delaglio, S. Grzesiek, G.W. Vuister, G. Zhu, J. Pfeifer, and A. Bax NMRPipe: a multidimensional spectral processing system based on UNIX pipes J Biomol NMR 6 1995 277 293
37. G.A. Cook, and S.J. Opella NMR studies of p7 protein from hepatitis C virus Eur Biophys J 39 2010 1097 1104