The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release

PLoS Pathogens

Volumn 7, Issue 6, 2011, Pages

  Raghava, Smita ^a   Giorda, Kristina M ^a   Romano, Fabian B ^a   Heuck, Alejandro P ^a   Hebert, Daniel N ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; LIPID; LIPOSOME; PHOSPHATIDYLETHANOLAMINE; PROTEIN VIROPORIN; PROTEIN VP4; UNCLASSIFIED DRUG; VIRUS PROTEIN; PORIN;

ANIMAL CELL; ARTICLE; BACTERIAL MEMBRANE; BACTERIUM; CELL MEMBRANE; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; ERYTHROCYTE; ESCHERICHIA COLI; FLOTATION; FLUORESCENCE; HEMOLYSIS; HOST CELL; HYDROPHOBICITY; MAMMAL CELL; MEMBRANE BINDING; MEMBRANE DAMAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIMIAN VIRUS 40; VIRUS RELEASE; FLUORESCENT ANTIBODY TECHNIQUE; GENE DELETION; GENETICS; METABOLISM; PHYSIOLOGY; POROSITY; VIROLOGY;

BACTERIA (MICROORGANISMS); MAMMALIA;

CELL MEMBRANE; FLUORESCENT ANTIBODY TECHNIQUE; GLUTATHIONE TRANSFERASE; LIPOSOMES; PHOSPHATIDYLETHANOLAMINES; PORINS; POROSITY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SIMIAN VIRUS 40; VIRAL STRUCTURAL PROTEINS; VIRUS RELEASE;

EID: 79959832190     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002116     Document Type: Article

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