메뉴 건너뛰기




Volumn 72, Issue 5, 1998, Pages 3560-3570

Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN; VIRUS RNA;

EID: 0031968980     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.5.3560-3570.1998     Document Type: Article
Times cited : (33)

References (51)
  • 1
    • 0029814801 scopus 로고    scopus 로고
    • Membrane permeabilization by poliovirus proteins 2B and 2BC
    • Aldabe, R., A. Barco, and L. Carrasco. 1996. Membrane permeabilization by poliovirus proteins 2B and 2BC. J. Biol. Chem. 271:23134-23137.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23134-23137
    • Aldabe, R.1    Barco, A.2    Carrasco, L.3
  • 2
    • 0028812170 scopus 로고
    • Induction of membrane proliferation by poliovirus proteins 2C and 2BC
    • Aldabe, R., and L. Carrasco. 1995. Induction of membrane proliferation by poliovirus proteins 2C and 2BC. Biochem. Biophys. Res. Commun. 206:64-76.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 64-76
    • Aldabe, R.1    Carrasco, L.2
  • 3
    • 0030834131 scopus 로고    scopus 로고
    • Poliovirus protein 2BC increases cytosolic free calcium concentrations
    • Aldabe, R., A. Irurzun, and L. Carrasco. 1997. Poliovirus protein 2BC increases cytosolic free calcium concentrations. J. Virol. 71:6214-6217.
    • (1997) J. Virol. , vol.71 , pp. 6214-6217
    • Aldabe, R.1    Irurzun, A.2    Carrasco, L.3
  • 4
    • 0024453841 scopus 로고
    • Guanidine-resistant mutants of poliovirus have distinct mutations in peptide 2C
    • Baltera, R. F. J., and D. R. Tershak. 1989. Guanidine-resistant mutants of poliovirus have distinct mutations in peptide 2C. J. Virol. 63:4441-4444.
    • (1989) J. Virol. , vol.63 , pp. 4441-4444
    • Baltera, R.F.J.1    Tershak, D.R.2
  • 5
    • 0024095176 scopus 로고
    • Organelle assembly in yeast: Characterization of yeast mutants defective in vacuolar biogenesis and protein sorting
    • Banta, L. M., J. S. Robinson, D. J. Klionsky, and S. D. Emr. 1988. Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J. Cell Biol. 107:1369-1383.
    • (1988) J. Cell Biol. , vol.107 , pp. 1369-1383
    • Banta, L.M.1    Robinson, J.S.2    Klionsky, D.J.3    Emr, S.D.4
  • 6
    • 0029036230 scopus 로고
    • A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae
    • Barco, A., and L. Carrasco. 1995. A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae. EMBO J. 14:3349-3364.
    • (1995) EMBO J. , vol.14 , pp. 3349-3364
    • Barco, A.1    Carrasco, L.2
  • 7
    • 0030911736 scopus 로고    scopus 로고
    • The yeast Saccharomyces cerevisiae as a genetic system for obtaining variants of poliovirus protease 2A*
    • Barco, A., I. Ventoso, and L. Carrasco. 1997. The yeast Saccharomyces cerevisiae as a genetic system for obtaining variants of poliovirus protease 2A*. J. Biol. Chem. 272:12683-12691.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12683-12691
    • Barco, A.1    Ventoso, I.2    Carrasco, L.3
  • 8
    • 0023039399 scopus 로고
    • Genetic complementation among poliovirus mutants derived from an infectious cDNA clone
    • Bernstein, H. D., P. Sarnow, and D. Baltimore. 1986. Genetic complementation among poliovirus mutants derived from an infectious cDNA clone. J. Virol. 60:1040-1049.
    • (1986) J. Virol. , vol.60 , pp. 1040-1049
    • Bernstein, H.D.1    Sarnow, P.2    Baltimore, D.3
  • 9
    • 0023415083 scopus 로고
    • Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography
    • Bienz, K., D. Egger, and L. Pasamontes. 1987. Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography. Virology 160:220-226.
    • (1987) Virology , vol.160 , pp. 220-226
    • Bienz, K.1    Egger, D.2    Pasamontes, L.3
  • 10
    • 0018914644 scopus 로고
    • Kinetics and location of poliovirus macromolecular synthesis in correlation to virus-induced cytopathology
    • Bienz, K., D. Egger, Y. Rasser, and W. Bossart. 1980. Kinetics and location of poliovirus macromolecular synthesis in correlation to virus-induced cytopathology. Virology 100:390-399.
    • (1980) Virology , vol.100 , pp. 390-399
    • Bienz, K.1    Egger, D.2    Rasser, Y.3    Bossart, W.4
  • 11
    • 0021069227 scopus 로고
    • Intracellular distribution of poliovirus proteins and the induction of virus-specific cytoplasmic structures
    • Bienz, K., D. Egger, Y. Rasser, and W. Bossart. 1983. Intracellular distribution of poliovirus proteins and the induction of virus-specific cytoplasmic structures. Virology 131:39-48.
    • (1983) Virology , vol.131 , pp. 39-48
    • Bienz, K.1    Egger, D.2    Rasser, Y.3    Bossart, W.4
  • 12
    • 0025236535 scopus 로고
    • Structural organization of poliovirus RNA replication is mediated by viral proteins of the P2 genomic region
    • Bienz, K., D. Egger, M. Troxler, and L. Pasamontes. 1990. Structural organization of poliovirus RNA replication is mediated by viral proteins of the P2 genomic region. J. Virol. 64:1156-1163.
    • (1990) J. Virol. , vol.64 , pp. 1156-1163
    • Bienz, K.1    Egger, D.2    Troxler, M.3    Pasamontes, L.4
  • 13
    • 0014675182 scopus 로고
    • Membranous structures associated with translation and transcription of poliovirus RNA
    • Caliguiri, L. A., and I. Tamm. 1969. Membranous structures associated with translation and transcription of poliovirus RNA. Science 166:885-886.
    • (1969) Science , vol.166 , pp. 885-886
    • Caliguiri, L.A.1    Tamm, I.2
  • 14
    • 0018273255 scopus 로고
    • Membrane leakiness after viral infection and a new approach to the development of antiviral agents
    • Carrasco, L. 1978. Membrane leakiness after viral infection and a new approach to the development of antiviral agents. Nature 272:694-699.
    • (1978) Nature , vol.272 , pp. 694-699
    • Carrasco, L.1
  • 15
    • 0029107952 scopus 로고
    • Modification of membrane permeability by animal viruses
    • Carrasco, L. 1995. Modification of membrane permeability by animal viruses. Adv. Virus Res. 45:61-112.
    • (1995) Adv. Virus Res. , vol.45 , pp. 61-112
    • Carrasco, L.1
  • 16
    • 85054257991 scopus 로고
    • The regulation of translation in picornavirus-infected cells
    • L. Carrasco (ed.), CRC Press, Inc., Boca Raton, Fla.
    • Carrasco, L., and J. L. Castrillo. 1987. The regulation of translation in picornavirus-infected cells, p. 115-146. In L. Carrasco (ed.), Mechanisms of viral toxicity in animal cells. CRC Press, Inc., Boca Raton, Fla.
    • (1987) Mechanisms of Viral Toxicity in Animal Cells , pp. 115-146
    • Carrasco, L.1    Castrillo, J.L.2
  • 17
    • 0024581644 scopus 로고
    • Modification of membrane permeability by animal viruses
    • Carrasco, L., M. J. Otero, and J. L. Castrillo. 1989. Modification of membrane permeability by animal viruses. Pharmacol. Ther. 40:171-212.
    • (1989) Pharmacol. Ther. , vol.40 , pp. 171-212
    • Carrasco, L.1    Otero, M.J.2    Castrillo, J.L.3
  • 18
    • 0000615498 scopus 로고
    • Plasmid vectors carrying the replication origin of filamentous single-stranded phages
    • Cesareni, G., and J. A. H. Murray. 1987. Plasmid vectors carrying the replication origin of filamentous single-stranded phages. Genet. Eng. 9:135-153.
    • (1987) Genet. Eng. , vol.9 , pp. 135-153
    • Cesareni, G.1    Murray, J.A.H.2
  • 20
    • 0028037893 scopus 로고
    • Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells
    • Cho, M. W., N. Teterina, D. Egger, K. Bienz, and E. Ehrenfeld. 1994. Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells. Virology 202:129-145.
    • (1994) Virology , vol.202 , pp. 129-145
    • Cho, M.W.1    Teterina, N.2    Egger, D.3    Bienz, K.4    Ehrenfeld, E.5
  • 21
    • 0000115806 scopus 로고
    • Electron microscopic study of the formation of poliovirus
    • Dales, S., H. J. Eggers, I. Tamm, and G. E. Palade. 1965. Electron microscopic study of the formation of poliovirus. Virology 26:379-389.
    • (1965) Virology , vol.26 , pp. 379-389
    • Dales, S.1    Eggers, H.J.2    Tamm, I.3    Palade, G.E.4
  • 22
    • 0028918959 scopus 로고
    • Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A
    • Doedens, J. R., and K. Kirkegaard. 1995. Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14:894-907.
    • (1995) EMBO J. , vol.14 , pp. 894-907
    • Doedens, J.R.1    Kirkegaard, K.2
  • 23
    • 0029063814 scopus 로고
    • Amino terminal regions of poliovirus 2C protein mediate membrane binding
    • Echeverri, A. C., and A. Dasgupta. 1995. Amino terminal regions of poliovirus 2C protein mediate membrane binding. Virology 208:540-553.
    • (1995) Virology , vol.208 , pp. 540-553
    • Echeverri, A.C.1    Dasgupta, A.2
  • 24
    • 0019444481 scopus 로고
    • Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast
    • Esmon, B., P. Novick, and R. Schekman. 1981. Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast. Cell 25:451-460.
    • (1981) Cell , vol.25 , pp. 451-460
    • Esmon, B.1    Novick, P.2    Schekman, R.3
  • 25
    • 0024433708 scopus 로고
    • Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation
    • Franzusoff, A., and R. Schekman. 1989. Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation. EMBO J. 8:2695-2702.
    • (1989) EMBO J. , vol.8 , pp. 2695-2702
    • Franzusoff, A.1    Schekman, R.2
  • 26
    • 0025261685 scopus 로고
    • A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses
    • Gorbalenya, A. E., E. V. Koonin, and Y. I. Wolf. 1990. A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses. FEBS Lett. 262:145-148.
    • (1990) FEBS Lett. , vol.262 , pp. 145-148
    • Gorbalenya, A.E.1    Koonin, E.V.2    Wolf, Y.I.3
  • 27
    • 0027531853 scopus 로고
    • Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway
    • Graham, T. R., P. A. Scott, and S. D. Emr. 1993. Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway. EMBO J. 12:869-877.
    • (1993) EMBO J. , vol.12 , pp. 869-877
    • Graham, T.R.1    Scott, P.A.2    Emr, S.D.3
  • 28
    • 0025328822 scopus 로고
    • Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena
    • Guinea, R., and L. Carrasco. 1990. Phospholipid biosynthesis and poliovirus genome replication, two coupled phenomena. EMBO J. 9:2011-2016.
    • (1990) EMBO J. , vol.9 , pp. 2011-2016
    • Guinea, R.1    Carrasco, L.2
  • 29
    • 0029067810 scopus 로고
    • Enhanced intracellular calcium concentration during poliovirus infection
    • Irurzun, A., J. Arroyo, A. Alvarez, and L. Carrasco. 1995. Enhanced intracellular calcium concentration during poliovirus infection. J. Virol. 69:5142-5146.
    • (1995) J. Virol. , vol.69 , pp. 5142-5146
    • Irurzun, A.1    Arroyo, J.2    Alvarez, A.3    Carrasco, L.4
  • 30
    • 0027247673 scopus 로고
    • Enhancement of phospholipase C activity during poliovirus infection
    • Irurzun, A., L. Perez, and L. Carrasco. 1993. Enhancement of phospholipase C activity during poliovirus infection. J. Gen. Virol. 74:1063-1071.
    • (1993) J. Gen. Virol. , vol.74 , pp. 1063-1071
    • Irurzun, A.1    Perez, L.2    Carrasco, L.3
  • 31
    • 0025835611 scopus 로고
    • Three poliovirus 2B mutants exhibit noncomplementable defects in viral RNA amplification and display dosage-dependent dominance over wild-type poliovirus
    • Johnson, K., and P. Sarnow. 1991. Three poliovirus 2B mutants exhibit noncomplementable defects in viral RNA amplification and display dosage-dependent dominance over wild-type poliovirus. J. Virol. 65:4341-4349.
    • (1991) J. Virol. , vol.65 , pp. 4341-4349
    • Johnson, K.1    Sarnow, P.2
  • 32
    • 0018409607 scopus 로고
    • The cytoskeletal framework and poliovirus metabolism
    • Lenk, R., and S. Penman. 1979. The cytoskeletal framework and poliovirus metabolism. Cell 16:289-301.
    • (1979) Cell , vol.16 , pp. 289-301
    • Lenk, R.1    Penman, S.2
  • 33
    • 0023724339 scopus 로고
    • Isolation of poliovirus 2C mutants defective in viral RNA synthesis
    • Li, J. P., and D. Baltimore. 1988. Isolation of poliovirus 2C mutants defective in viral RNA synthesis. J. Virol. 62:4016-4021.
    • (1988) J. Virol. , vol.62 , pp. 4016-4021
    • Li, J.P.1    Baltimore, D.2
  • 34
    • 0025213458 scopus 로고
    • An intragenic revertant of a poliovirus 2C mutant has an uncoating defect
    • Li, J. P., and D. Baltimore. 1990. An intragenic revertant of a poliovirus 2C mutant has an uncoating defect. J. Virol. 64:1102-1107.
    • (1990) J. Virol. , vol.64 , pp. 1102-1107
    • Li, J.P.1    Baltimore, D.2
  • 35
    • 0028355633 scopus 로고
    • Biochemical studies on poliovirus polypeptide 2C: Evidence for ATPase activity
    • Mirzayan, C., and E. Wimmer. 1994. Biochemical studies on poliovirus polypeptide 2C: evidence for ATPase activity. Virology 199:176-187.
    • (1994) Virology , vol.199 , pp. 176-187
    • Mirzayan, C.1    Wimmer, E.2
  • 36
    • 0022623016 scopus 로고
    • Guanidine-selected mutants of poliovirus: Mapping of point mutations to polypeptide 2C
    • Pincus, S. E., D. C. Diamond, E. A. Emini, and E. Wimmer. 1986. Guanidine-selected mutants of poliovirus: mapping of point mutations to polypeptide 2C. J. Virol. 57:638-646.
    • (1986) J. Virol. , vol.57 , pp. 638-646
    • Pincus, S.E.1    Diamond, D.C.2    Emini, E.A.3    Wimmer, E.4
  • 37
    • 0023001243 scopus 로고
    • Production of guanidine-resistant and -dependent poliovirus mutants from cloned cDNA: Mutations in polypeptide 2C are directly responsible for altered guanidine sensitivity
    • Pincus, S. E., and E. Wimmer. 1986. Production of guanidine-resistant and -dependent poliovirus mutants from cloned cDNA: mutations in polypeptide 2C are directly responsible for altered guanidine sensitivity. J. Virol. 60:793-796.
    • (1986) J. Virol. , vol.60 , pp. 793-796
    • Pincus, S.E.1    Wimmer, E.2
  • 38
    • 0027537974 scopus 로고
    • Poliovirus protein 2C has ATPase and GTPase activities
    • Rodríguez, P. L., and L. Carrasco. 1993. Poliovirus protein 2C has ATPase and GTPase activities. J. Biol. Chem. 268:8105-8110.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8105-8110
    • Rodríguez, P.L.1    Carrasco, L.2
  • 39
    • 0028925901 scopus 로고
    • Poliovirus protein 2C contains two regions involved in RNA binding activity
    • Rodríguez, P. L., and L. Carrasco. 1995. Poliovirus protein 2C contains two regions involved in RNA binding activity. J. Biol. Chem. 270:10105-10112.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10105-10112
    • Rodríguez, P.L.1    Carrasco, L.2
  • 42
    • 0030925288 scopus 로고    scopus 로고
    • Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179
    • Sandoval, I. V., and L. Carrasco. 1997. Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179. J. Virol. 71:4679-4693.
    • (1997) J. Virol. , vol.71 , pp. 4679-4693
    • Sandoval, I.V.1    Carrasco, L.2
  • 43
    • 0029794678 scopus 로고    scopus 로고
    • Cellular origin and ultrastructure of membranes induced during poliovirus infection
    • Schlegel, A., T. H. Giddings, M. S. Ladinsky, and K. Kirkegaard. 1996. Cellular origin and ultrastructure of membranes induced during poliovirus infection. J. Virol. 70:6576-6588.
    • (1996) J. Virol. , vol.70 , pp. 6576-6588
    • Schlegel, A.1    Giddings, T.H.2    Ladinsky, M.S.3    Kirkegaard, K.4
  • 45
    • 0029951824 scopus 로고    scopus 로고
    • Coxsackie B3 virus protein 2B contains a cationic amphipathic helix that is required for viral RNA replication
    • van Kuppeveld, F. J. M., J. M. D. Galama, J. Zoll, P. J. J. C. Van den Hurk, and W. J. G. Melchers. 1996. Coxsackie B3 virus protein 2B contains a cationic amphipathic helix that is required for viral RNA replication. J. Virol. 70:3876-3886.
    • (1996) J. Virol. , vol.70 , pp. 3876-3886
    • Van Kuppeveld, F.J.M.1    Galama, J.M.D.2    Zoll, J.3    Van Den Hurk, P.J.J.C.4    Melchers, W.J.G.5
  • 46
    • 0028871749 scopus 로고
    • Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: A moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis
    • van Kuppeveld, F. J. M., J. M. D. Galama, J. Zoll, J. J. C. van den Hurk, and W. J. G. Melchers. 1995. Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis. J. Virol. 69:7782-7790.
    • (1995) J. Virol. , vol.69 , pp. 7782-7790
    • Van Kuppeveld, F.J.M.1    Galama, J.M.D.2    Zoll, J.3    Van Den Hurk, J.J.C.4    Melchers, W.J.G.5
  • 49
    • 0027732208 scopus 로고
    • Overexpression of the ER-membrane protein P-450 CYP52A3 mimics sec mutant characteristics in Saccharomyces cerevisiae
    • Wiedmann, B., P. Silver, W.-H. Schunck, and M. Wiedmann. 1993. Overexpression of the ER-membrane protein P-450 CYP52A3 mimics sec mutant characteristics in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1153: 267-276.
    • (1993) Biochim. Biophys. Acta , vol.1153 , pp. 267-276
    • Wiedmann, B.1    Silver, P.2    Schunck, W.-H.3    Wiedmann, M.4
  • 50
    • 0023788653 scopus 로고
    • Increased amounts of HMG-CoA reductase induce "Karmellae": A proliferation of stacked membrane pairs surrounding the yeast nucleus
    • Wright, R., M. Basson, L. D'Ari, and J. Rine. 1988. Increased amounts of HMG-CoA reductase induce "Karmellae": a proliferation of stacked membrane pairs surrounding the yeast nucleus. J. Cell Biol. 107:101-114.
    • (1988) J. Cell Biol. , vol.107 , pp. 101-114
    • Wright, R.1    Basson, M.2    D'Ari, L.3    Rine, J.4
  • 51
    • 0000856498 scopus 로고
    • Two nuclear mutations that block mitochondrial protein import in yeast
    • Yaffe, M. P., and G. Schatz. 1984. Two nuclear mutations that block mitochondrial protein import in yeast. Proc. Natl. Acad. Sci. USA 81:4819-4823.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4819-4823
    • Yaffe, M.P.1    Schatz, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.