Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus P7 protein in vitro

Journal of Biological Chemistry

Volumn 281, Issue 48, 2006, Pages 37057-37068

  Clarke, Dean ^a   Griffin, Stephen ^a   Beales, Lucy ^a   Gelais, Corine St ^a   Burgess, Stan ^a   Harris, Mark ^a   Rowlands, David ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; BACTERIAL EXPRESSION SYSTEM; ION CHANNEL COMPLEX;

ANTIBIOTICS; BIOASSAY; DERIVATIVES; ENZYME INHIBITION; SUGARS; SYNTHESIS (CHEMICAL); VIRUSES;

PROTEINS;

AMANTADINE; DETERGENT; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; ION CHANNEL; LIPOSOME; N LAURYL SARCOSINE; OLIGOMER; PEPTIDES AND PROTEINS; PROTEIN FLAG; PROTEIN P17; SARCOSINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; HEPATITIS C VIRUS; HYDROPHOBICITY; IN VITRO STUDY; LIPID BILAYER; MASS SPECTROMETRY; NONHUMAN; OLIGOMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; STOICHIOMETRY; TRANSMISSION ELECTRON MICROSCOPY;

AMANTADINE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; GLUTATHIONE TRANSFERASE; ION CHANNELS; LIPID BILAYERS; MICROSCOPY, ELECTRON, TRANSMISSION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SWINE; VIRAL PROTEINS;

BACTERIA (MICROORGANISMS); HEPATITIS C VIRUS;

EID: 33846005485     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602434200     Document Type: Article

References (40)

1. Pawlotsky, J. M. (2003) Curr. Opin. Infect. Dis. 16, 587-592
2. Simmonds, P. (1997) Gut 40, 291-293
3. Deltenre, P., Henrion, J., Canva, V., Dharancy, S., Texier, F., Louvet, A., De Maeght, S., Paris, J. C., and Mathurin, P. (2004) J. Hepatol. 41, 462-473
4. Choo, Q. L., Kuo, G., Weiner, A. J., Overby, L. R., Bradley, D. W., and Houghton, M. (1989) Science 244, 359-362
5. Lohmann, V., Koch, J. O., and Bartenschlager, R. (1996) J. Hepatol. 24, 11-19
6. Moradpour, D., Gosert, R., Egger, D., Penin, F., Blum, H. E., and Bienz, K. (2003) Antiviral Res. 60, 103-109
7. Lin, C., Lindenbach, B. D., Pragai, B. M., McCourt, D. W., and Rice, C. M. (1994) J. Virol. 68, 5063-5073
8. Carrere-Kremer, S., Montpellier-Pala, C., Cocquerel, L., Wychowski, C., Penin, F., and Dubuisson, J. (2002) J. Virol. 76, 3720-3730
9. Griffin, S. D., Beales, L. P., Clarke, D. S., Worsfold, O., Evans, S. D., Jaeger, J., Harris, M. P., and Rowlands, D. J. (2003) FEBS Lett. 535, 34-38
10. Pavlovic, D., Neville, D. C., Argaud, O., Blumberg, B., Dwek, R. A., Fischer, W. B., and Zitzmann, N. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 6104-6108
11. Premkumar, A., Wilson, L., Ewart, G. D., and Gage, P. W. (2004) FEBS Lett. 557, 99-103
12. Sakai, A., Claire, M. S., Faulk, K., Govindarajan, S., Emerson, S. U., Purcell, R. H., and Bukh, J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 11646-11651
13. Harada, T., Tautz, N., and Thiel, H. J. (2000) J. Virol. 74, 9498-9506
14. Gonzalez, M. E., and Carrasco, L. (2003) FEBS Lett. 552, 28-34
15. Hay, A. J., Wolstenholme, A. J., Skehel, J. J., and Smith, M. H. (1985) EMBO J. 4, 3021-3024
16. Griffin, S. D., Harvey, R., Clarke, D. S., Barclay, W. S., Harris, M., and Rowlands, D. J. (2004) J. Gen. Virol. 85, 451-461
17. Pinto, L. H., Dieckmann, G. R., Gandhi, C. S., Papworth, C. G., Braman, J., Shaughnessy, M. A., Lear, J. D., Lamb, R. A., and DeGrado, W. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11301-11306
18. Song, Z., Kovacs, F. A., Wang, J., Denny, J. K., Shekar, S. C., Quine, J. R., and Cross, T. A. (2000) Biophys. J. 79, 767-775
19. Salom, D., Hill, B. R., Lear, J. D., and DeGrado, W. F. (2000) Biochemistry 39, 14160-14170
20. Stouffer, A. L., Nanda, V., Lear, J. D., and DeGrado, W. F. (2005) J. Mol. Biol. 347, 169-179
21. Sakaguchi, T., Tu, Q., Pinto, L. H., and Lamb, R. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5000-5005
22. Duff, K. C., and Ashley, R. H. (1992) Virology 190, 485-489
23. Pinto, L. H., Holsinger, L. J., and Lamb, R. A. (1992) Cell 69, 517-528
24. Tang, Y., Zaitseva, F., Lamb, R. A., and Pinto, L. H. (2002) J. Biol. Chem. 277, 39880-39886
25. Wang, J., Kim, S., Kovacs, F., and Cross, T. A. (2001) Protein Sci. 10, 2241-2250
26. Yanagi, M., St Claire, M., Shapiro, M., Emerson, S. U., Purcell, R. H., and Bukh, J. (1998) Virology 244, 161-172
27. Griffin, S., Clarke, D., McCormick, C., Rowlands, D., and Harris, M. (2005) J. Virol. 79, 15525-15536
28. Frank J. (2005) Three-Dimensional Electron Microscopy of Macromolecular Assemblies, Visualization of Biological Molecules in Their Native State, Oxford University Press, Oxford, UK
29. Burgess, S. A., Walker, M. L., White, H. D., and Trinick, J. (1997) J. Cell Biol. 139, 675-681
30. Botting, C. H. (2000) Rapid Commun. Mass Spectrom. 14, 2030-2033
31. Holsinger, L. J., and Lamb, R. A. (1991) Virology 183, 32-43
32. Kukol, A., and Arkin, I. T. (1999) Biophys. J. 77, 1594-1601
33. Agirre, A., Barco, A., Carrasco, L., and Nieva, J. L. (2002) J. Biol. Chem. 277, 40434-40441
34. de Jong, A. S., Melchers, W. J., Glaudemans, D. H., Willems, P. H., and van Kuppeveld, F. J. (2004) J. Biol. Chem. 279, 19924-19935
35. Lindenbach, B. D., Evans, M. J., Syder, A. J., Wolk, B., Tellinghuisen, T. L., Liu, C. C., Maruyama, T., Hynes, R. O., Burton, D. R., McKeating, J. A., and Rice, C. M. (2005) Science 309, 623-626
36. Wakita, T., Pietschmann, T., Kato, T., Date, T., Miyamoto, M., Zhao, Z., Murthy, K., Habermann, A., Krausslich, H. G., Mizokami, M., Bartenschlager, R., and Liang, T. J. (2005) Nat. Med. 11, 791-796
37. Zhong, J., Gastaminza, P., Cheng, G., Kapadia, S., Kato, T., Burton, D. R., Wieland, S. F., Uprichard, S. L., Wakita, T., and Chisari, F. V. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 9294-9299
38. Gurezka, R., Laage, R., Brosig, B., and Langosch, D. (1999) J. Biol. Chem. 274, 9265-9270
39. Russ, W. P., and Engelman, D. M. (2000) J. Mol. Biol. 296, 911-919
40. Orzaez, M., Lukovic, D., Abad, C., Perez-Paya, E., and Mingarro, I. (2005) FEBS Lett. 579, 1633-1638