The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

FEBS Letters

Volumn 535, Issue 1-3, 2003, Pages 34-38

  Griffin, Stephen D C ^a   Beales, Lucy P ^a   Clarke, Dean S ^a   Worsfold, Oliver ^b   Evans, Stephen D ^a   Jaeger, Joachim ^a   Harris, Mark P G ^a   Rowlands, David J ^a   Klenk, Hans Dieter ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b FUJIREBIO INC   (Japan)

^c University of Leeds ^*

Author keywords

Amantadine; Antiviral therapy; Flavivirus; Hepatitis C virus; p7; Viroporin

Indexed keywords

AMANTADINE; CALCIUM CHANNEL; PROTEIN P7; UNCLASSIFIED DRUG; VIRUS PROTEIN;

CONFERENCE PAPER; CONTROLLED STUDY; CROSS LINKING; DRUG EFFECT; ESCHERICHIA COLI; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID MEMBRANE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION;

ESCHERICHIA COLI; FLAVIVIRUS; HEPATITIS C VIRUS;

EID: 0037472806     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)03851-6     Document Type: Conference Paper

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