Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 29, 2012, Pages 11681-11686

  Bowman, Gregory R ^a   Geissler, Phillip L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Molecular dynamics; Native state dynamics

Indexed keywords

AMINO ACID; BETA LACTAMASE; INTERLEUKIN 2; RIBONUCLEASE H;

ARTICLE; BINDING SITE; COMPUTER SIMULATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROBABILITY; PROTEIN FOLDING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; BETA-LACTAMASES; INTERLEUKIN-2; MODELS, CHEMICAL; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN FOLDING; RIBONUCLEASE H;

EID: 84863939894     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209309109     Document Type: Article

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