Induced fit or conformational selection? the role of the semi-closed state in the maltose binding protein

Biochemistry

Volumn 50, Issue 48, 2011, Pages 10530-10539

  Bucher, Denis ^a   Grant, Barry J ^a,b   McCammon, J Andrew ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCELERATED MOLECULAR DYNAMICS; BIOLOGICAL PROCESS; CONFORMATIONAL CHANGE; CONFORMATIONAL SELECTION; CONFORMATIONAL STATE; DRUG DISCOVERY; ENERGY METHOD; ENZYMATIC ACTIVITIES; FLEXIBLE DOCKING; FREE ENERGY CHANGE; INDUCED FIT; LIGAND RECOGNITION; MALTOSE BINDING PROTEINS; NATURALLY OCCURRING; RECOGNITION MECHANISM; RECOGNITION PROCESS; RELATIVE ENERGIES; SIDE-CHAINS; STABLE STATE; THERMODYNAMIC FORCES; THERMODYNAMIC INTEGRATION; TIME-SCALES;

EXPERIMENTS; FREE ENERGY; LIGANDS; MALTOSE; MOLECULAR DYNAMICS; PROTEINS;

BINDING ENERGY;

MALTOSE BINDING PROTEIN;

ADAPTIVELY BIASED FORCE; AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; CONFORMATION; CONFORMATIONAL SELECTION; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; THERMODYNAMIC INTEGRATION FREE ENERGY METHOD; VIBRATION;

BINDING SITES; COMPUTER SIMULATION; LIGANDS; MALTOSE-BINDING PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; THERMODYNAMICS; TRISACCHARIDES;

EID: 82455171948     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201481a     Document Type: Article

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