메뉴 건너뛰기




Volumn 198, Issue , 2012, Pages 25-46

Respiration and autonomic regulation and orexin

Author keywords

Almorexant; Blood pressure; Chemoreception; Orexin

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; ALMOREXANT; CARBON DIOXIDE; OREXIN; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; OREXIN A; OREXIN B; OXYGEN; STRESS HORMONE;

EID: 84863883078     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-59489-1.00004-5     Document Type: Chapter
Times cited : (73)

References (116)
  • 2
    • 58149313606 scopus 로고    scopus 로고
    • The hypocretins as sensors for metabolism and arousal
    • Adamantidis A., de Lecea L. The hypocretins as sensors for metabolism and arousal. The Journal of Physiology 2009, 587:33-40.
    • (2009) The Journal of Physiology , vol.587 , pp. 33-40
    • Adamantidis, A.1    de Lecea, L.2
  • 4
    • 0015074594 scopus 로고
    • Origin and regulation of spontaneous deep breaths
    • Bartlett D.J. Origin and regulation of spontaneous deep breaths. Respiration Physiology 1973, 12:230-238.
    • (1973) Respiration Physiology , vol.12 , pp. 230-238
    • Bartlett, D.J.1
  • 5
    • 79851498092 scopus 로고    scopus 로고
    • Sleep related changes in blood pressure in hypocretin-deficient narcoleptic mice
    • Bastianini S., Silvani A., Berteotti C., Elghozi J.L., Franzini C., Lenzi P., et al. Sleep related changes in blood pressure in hypocretin-deficient narcoleptic mice. Sleep 2011, 34:213-218.
    • (2011) Sleep , vol.34 , pp. 213-218
    • Bastianini, S.1    Silvani, A.2    Berteotti, C.3    Elghozi, J.L.4    Franzini, C.5    Lenzi, P.6
  • 6
    • 24944446762 scopus 로고    scopus 로고
    • Hypocretins (orexins) and sleep-wake disorders
    • Baumann C.R., Bassetti C.L. Hypocretins (orexins) and sleep-wake disorders. Lancet Neurology 2005, 4:673-682.
    • (2005) Lancet Neurology , vol.4 , pp. 673-682
    • Baumann, C.R.1    Bassetti, C.L.2
  • 7
    • 75449095217 scopus 로고    scopus 로고
    • The role of hypocretin in driving arousal and goal-oriented behaviors
    • Boutrel B., Cannella N., de Lecea L. The role of hypocretin in driving arousal and goal-oriented behaviors. Brain Research 2009, 1314:103-111.
    • (2009) Brain Research , vol.1314 , pp. 103-111
    • Boutrel, B.1    Cannella, N.2    de Lecea, L.3
  • 11
    • 0033588184 scopus 로고    scopus 로고
    • Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
    • Chemelli R.M., Willie J.T., Sinton C.M., Elmquist J.K., Scammell T., Lee C., et al. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation. Cell 1999, 98:437-451.
    • (1999) Cell , vol.98 , pp. 437-451
    • Chemelli, R.M.1    Willie, J.T.2    Sinton, C.M.3    Elmquist, J.K.4    Scammell, T.5    Lee, C.6
  • 14
    • 0022852157 scopus 로고
    • Sleep apnea in narcolepsy
    • Chokroverty S. Sleep apnea in narcolepsy. Sleep 1986, 9:250-253.
    • (1986) Sleep , vol.9 , pp. 250-253
    • Chokroverty, S.1
  • 16
    • 0142122405 scopus 로고    scopus 로고
    • Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla
    • Ciriello J., Li Z., de Oliveira C.V. Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla. Brain Research 2003, 991:84-95.
    • (2003) Brain Research , vol.991 , pp. 84-95
    • Ciriello, J.1    Li, Z.2    de Oliveira, C.V.3
  • 18
    • 77949570581 scopus 로고    scopus 로고
    • + dialysis in the caudal ventrolateral medulla (Loeschcke's area) increases ventilation in wakefulness
    • + dialysis in the caudal ventrolateral medulla (Loeschcke's area) increases ventilation in wakefulness. Respiratory Physiology & Neurobiology 2010, 171:46-53.
    • (2010) Respiratory Physiology & Neurobiology , vol.171 , pp. 46-53
    • da Silva, G.S.1    Li, A.2    Nattie, E.3
  • 19
    • 75749108530 scopus 로고    scopus 로고
    • A decade of Hypocretins: Past, present and future of the neurobiology of arousal
    • de Lecea L. A decade of Hypocretins: Past, present and future of the neurobiology of arousal. Acta Physiologica (Oxford, England) 2009, 198:203-208.
    • (2009) Acta Physiologica (Oxford, England) , vol.198 , pp. 203-208
    • de Lecea, L.1
  • 21
    • 0142058834 scopus 로고    scopus 로고
    • Cardiovascular responses to hypocretin-1 in nucleus ambiguus of the ovariectomized female rat
    • de Oliveira C.V., Ciriello J. Cardiovascular responses to hypocretin-1 in nucleus ambiguus of the ovariectomized female rat. Brain Research 2003, 986:148-156.
    • (2003) Brain Research , vol.986 , pp. 148-156
    • de Oliveira, C.V.1    Ciriello, J.2
  • 23
    • 35648987905 scopus 로고    scopus 로고
    • Contribution of orexin in hypercapnic chemoreflex: Evidence from genetic and pharmacological disruption and supplementation studies in mice
    • Deng B.S., Nakamura A., Zhang W., Yanagisawa M., Fukuda Y., Kuwaki T. Contribution of orexin in hypercapnic chemoreflex: Evidence from genetic and pharmacological disruption and supplementation studies in mice. Journal of Applied Physiology 2007, 103:1772-1779.
    • (2007) Journal of Applied Physiology , vol.103 , pp. 1772-1779
    • Deng, B.S.1    Nakamura, A.2    Zhang, W.3    Yanagisawa, M.4    Fukuda, Y.5    Kuwaki, T.6
  • 25
    • 65449121472 scopus 로고    scopus 로고
    • Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness
    • Dias M.B., Li A., Nattie E.E. Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness. The Journal of Physiology 2009, 587:2059-2067.
    • (2009) The Journal of Physiology , vol.587 , pp. 2059-2067
    • Dias, M.B.1    Li, A.2    Nattie, E.E.3
  • 26
    • 74449083517 scopus 로고    scopus 로고
    • The orexin receptor 1 (OX1R) in the rostral medullary raphe contributes to the hypercapnic chemoreflex in wakefulness, during the active period of the diurnal cycle
    • Dias M.B., Li A., Nattie E. The orexin receptor 1 (OX1R) in the rostral medullary raphe contributes to the hypercapnic chemoreflex in wakefulness, during the active period of the diurnal cycle. Respiratory Physiology & Neurobiology 2010, 170:96-102.
    • (2010) Respiratory Physiology & Neurobiology , vol.170 , pp. 96-102
    • Dias, M.B.1    Li, A.2    Nattie, E.3
  • 27
    • 0026480346 scopus 로고
    • In vitro responses of caudal hypothalamic neurons to hypoxia and hypercapnia
    • Dillon G.H., Waldrop T.G. In vitro responses of caudal hypothalamic neurons to hypoxia and hypercapnia. Neuroscience 1992, 51:941-950.
    • (1992) Neuroscience , vol.51 , pp. 941-950
    • Dillon, G.H.1    Waldrop, T.G.2
  • 30
    • 35248884442 scopus 로고    scopus 로고
    • Activation of Orexin B receptors in the pontine Kolliker-Fuse nucleus modulates pre-inspiratory hypoglossal motor activity in rat
    • Dutschmann M., Kron M., Morschel M., Gestreau C. Activation of Orexin B receptors in the pontine Kolliker-Fuse nucleus modulates pre-inspiratory hypoglossal motor activity in rat. Respiratory Physiology & Neurobiology 2007, 159:232-235.
    • (2007) Respiratory Physiology & Neurobiology , vol.159 , pp. 232-235
    • Dutschmann, M.1    Kron, M.2    Morschel, M.3    Gestreau, C.4
  • 34
    • 55149112578 scopus 로고    scopus 로고
    • The dual role of the orexin/hypocretin system in modulating wakefulness and respiratory drive
    • Gestreau C., Bevengut M., Dutschmann M. The dual role of the orexin/hypocretin system in modulating wakefulness and respiratory drive. Current Opinion in Pulmonary Medicine 2008, 14:512-518.
    • (2008) Current Opinion in Pulmonary Medicine , vol.14 , pp. 512-518
    • Gestreau, C.1    Bevengut, M.2    Dutschmann, M.3
  • 35
    • 84859161481 scopus 로고    scopus 로고
    • Respiratory regulation in narcolepsy
    • Han F. Respiratory regulation in narcolepsy. Sleep & breathing = Schlaf & Atmung 2011, 16:241-245.
    • (2011) Sleep & breathing = Schlaf & Atmung , vol.16 , pp. 241-245
    • Han, F.1
  • 37
    • 0034992322 scopus 로고    scopus 로고
    • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
    • Hara J., Beuckmann C.T., Nambu T., Willie J.T., Chemelli R.M., Sinton C.M., et al. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron 2001, 30:345-354.
    • (2001) Neuron , vol.30 , pp. 345-354
    • Hara, J.1    Beuckmann, C.T.2    Nambu, T.3    Willie, J.T.4    Chemelli, R.M.5    Sinton, C.M.6
  • 38
    • 18144370824 scopus 로고    scopus 로고
    • Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions
    • Hara J., Yanagisawa M., Sakurai T. Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions. Neuroscience Letters 2005, 380:239-242.
    • (2005) Neuroscience Letters , vol.380 , pp. 239-242
    • Hara, J.1    Yanagisawa, M.2    Sakurai, T.3
  • 39
    • 0035925698 scopus 로고    scopus 로고
    • Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord
    • Hervieu G.J., Cluderay J.E., Harrison D.C., Roberts J.C., Leslie R.A. Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord. Neuroscience 2001, 103:777-797.
    • (2001) Neuroscience , vol.103 , pp. 777-797
    • Hervieu, G.J.1    Cluderay, J.E.2    Harrison, D.C.3    Roberts, J.C.4    Leslie, R.A.5
  • 40
    • 0141463751 scopus 로고    scopus 로고
    • Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats
    • Hirota K., Kushikata T., Kudo M., Kudo T., Smart D., Matsuki A. Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats. Brain Research 2003, 981:143-150.
    • (2003) Brain Research , vol.981 , pp. 143-150
    • Hirota, K.1    Kushikata, T.2    Kudo, M.3    Kudo, T.4    Smart, D.5    Matsuki, A.6
  • 43
    • 77957016202 scopus 로고    scopus 로고
    • Medullary serotonin neurons and their roles in central respiratory chemoreception
    • Hodges M.R., Richerson G.B. Medullary serotonin neurons and their roles in central respiratory chemoreception. Respiratory Physiology & Neurobiology 2010, 173:256-263.
    • (2010) Respiratory Physiology & Neurobiology , vol.173 , pp. 256-263
    • Hodges, M.R.1    Richerson, G.B.2
  • 45
    • 77954944602 scopus 로고    scopus 로고
    • Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors
    • Huang S.C., Dai Y.W., Lee Y.H., Chiou L.C., Hwang L.L. Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors. The Journal of Pharmacology and Experimental Therapeutics 2010, 334:522-529.
    • (2010) The Journal of Pharmacology and Experimental Therapeutics , vol.334 , pp. 522-529
    • Huang, S.C.1    Dai, Y.W.2    Lee, Y.H.3    Chiou, L.C.4    Hwang, L.L.5
  • 48
    • 27144454353 scopus 로고    scopus 로고
    • From waking to sleeping: Neuronal and chemical substrates
    • Jones B.E. From waking to sleeping: Neuronal and chemical substrates. Trends in Pharmacological Sciences 2005, 26:578-586.
    • (2005) Trends in Pharmacological Sciences , vol.26 , pp. 578-586
    • Jones, B.E.1
  • 49
    • 33846492891 scopus 로고    scopus 로고
    • Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus
    • Kannan H., Shirasaka T., Watanabe S., Yu N.S., Kuitake T., Takasaki M. Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus. Masui. The Japanese Journal of Anesthesiology 2007, 56:30-39.
    • (2007) Masui. The Japanese Journal of Anesthesiology , vol.56 , pp. 30-39
    • Kannan, H.1    Shirasaka, T.2    Watanabe, S.3    Yu, N.S.4    Kuitake, T.5    Takasaki, M.6
  • 53
    • 53849114680 scopus 로고    scopus 로고
    • Orexinergic modulation of breathing across vigilance states
    • Kuwaki T. Orexinergic modulation of breathing across vigilance states. Respiratory Physiology & Neurobiology 2008, 164:204-212.
    • (2008) Respiratory Physiology & Neurobiology , vol.164 , pp. 204-212
    • Kuwaki, T.1
  • 55
    • 79953739393 scopus 로고    scopus 로고
    • Orexin links emotional stress to autonomic functions
    • Kuwaki T. Orexin links emotional stress to autonomic functions. Autonomic Neuroscience: Basic & Clinical 2011, 161:20-27.
    • (2011) Autonomic Neuroscience: Basic & Clinical , vol.161 , pp. 20-27
    • Kuwaki, T.1
  • 57
    • 53049083582 scopus 로고    scopus 로고
    • Emotional and state-dependent modification of cardiorespiratory function: Role of orexinergic neurons
    • Kuwaki T., Zhang W., Nakamura A., Deng B.S. Emotional and state-dependent modification of cardiorespiratory function: Role of orexinergic neurons. Autonomic Neuroscience: Basic & Clinical 2008, 142:11-16.
    • (2008) Autonomic Neuroscience: Basic & Clinical , vol.142 , pp. 11-16
    • Kuwaki, T.1    Zhang, W.2    Nakamura, A.3    Deng, B.S.4
  • 60
    • 0037163848 scopus 로고    scopus 로고
    • 2 dialysis in one chemoreceptor site, the RTN: Stimulus intensity and sensitivity in the awake rat
    • 2 dialysis in one chemoreceptor site, the RTN: Stimulus intensity and sensitivity in the awake rat. Respiratory Physiology & Neurobiology 2002, 133:11-22.
    • (2002) Respiratory Physiology & Neurobiology , vol.133 , pp. 11-22
    • Li, A.1    Nattie, E.2
  • 61
    • 79251504455 scopus 로고    scopus 로고
    • Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle
    • Li A., Nattie E. Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle. The Journal of Physiology 2010, 588:2935-2944.
    • (2010) The Journal of Physiology , vol.588 , pp. 2935-2944
    • Li, A.1    Nattie, E.2
  • 62
    • 0032870171 scopus 로고    scopus 로고
    • CO(2) microdialysis in retrotrapezoid nucleus of the rat increases breathing in wakefulness but not in sleep
    • Li A., Randall M., Nattie E.E. CO(2) microdialysis in retrotrapezoid nucleus of the rat increases breathing in wakefulness but not in sleep. Journal of Applied Physiology 1999, 87:910-919.
    • (1999) Journal of Applied Physiology , vol.87 , pp. 910-919
    • Li, A.1    Randall, M.2    Nattie, E.E.3
  • 66
    • 0037086827 scopus 로고    scopus 로고
    • Pressor response to microinjection of orexin/hypocretin into rostral ventrolateral medulla of awake rats
    • Machado B.H., Bonagamba L.G., Dun S.L., Kwok E.H., Dun N.J. Pressor response to microinjection of orexin/hypocretin into rostral ventrolateral medulla of awake rats. Regulatory Peptides 2002, 104:75-81.
    • (2002) Regulatory Peptides , vol.104 , pp. 75-81
    • Machado, B.H.1    Bonagamba, L.G.2    Dun, S.L.3    Kwok, E.H.4    Dun, N.J.5
  • 67
    • 38449109952 scopus 로고    scopus 로고
    • Respiratory long-term facilitation: Too much or too little of a good thing?
    • Mahamed S., Mitchell G.S. Respiratory long-term facilitation: Too much or too little of a good thing?. Advances in Experimental Medicine and Biology 2008, 605:224-227.
    • (2008) Advances in Experimental Medicine and Biology , vol.605 , pp. 224-227
    • Mahamed, S.1    Mitchell, G.S.2
  • 69
    • 1642471928 scopus 로고    scopus 로고
    • Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity
    • Martins P.J., D'Almeida V., Pedrazzoli M., Lin L., Mignot E., Tufik S. Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regulatory Peptides 2004, 117:155-158.
    • (2004) Regulatory Peptides , vol.117 , pp. 155-158
    • Martins, P.J.1    D'Almeida, V.2    Pedrazzoli, M.3    Lin, L.4    Mignot, E.5    Tufik, S.6
  • 70
    • 0035571117 scopus 로고    scopus 로고
    • Central orexin-A augments sympathoadrenal outflow in conscious rabbits
    • Matsumura K., Tsuchihashi T., Abe I. Central orexin-A augments sympathoadrenal outflow in conscious rabbits. Hypertension 2001, 37:1382-1387.
    • (2001) Hypertension , vol.37 , pp. 1382-1387
    • Matsumura, K.1    Tsuchihashi, T.2    Abe, I.3
  • 71
    • 0038460863 scopus 로고    scopus 로고
    • Neural regulation of blood pressure by leptin and the related peptides
    • Matsumura K., Tsuchihashi T., Fujii K., Iida M. Neural regulation of blood pressure by leptin and the related peptides. Regulatory Peptides 2003, 114:79-86.
    • (2003) Regulatory Peptides , vol.114 , pp. 79-86
    • Matsumura, K.1    Tsuchihashi, T.2    Fujii, K.3    Iida, M.4
  • 72
    • 0036891958 scopus 로고    scopus 로고
    • Effect of hypoxic episode number and severity on ventilatory long-term facilitation in awake rats
    • McGuire M., Zhang Y., White D.P., Ling L. Effect of hypoxic episode number and severity on ventilatory long-term facilitation in awake rats. Journal of Applied Physiology 2002, 93:2155-2161.
    • (2002) Journal of Applied Physiology , vol.93 , pp. 2155-2161
    • McGuire, M.1    Zhang, Y.2    White, D.P.3    Ling, L.4
  • 73
    • 19544376694 scopus 로고    scopus 로고
    • Behavioral correlates of activity in identified hypocretin/orexin neurons
    • Mileykovskiy B.Y., Kiyashchenko L.I., Siegel J.M. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron 2005, 46:787-798.
    • (2005) Neuron , vol.46 , pp. 787-798
    • Mileykovskiy, B.Y.1    Kiyashchenko, L.I.2    Siegel, J.M.3
  • 76
    • 33846151399 scopus 로고    scopus 로고
    • Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice
    • Nakamura A., Zhang W., Yanagisawa M., Fukuda Y., Kuwaki T. Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice. Journal of Applied Physiology 2007, 102:241-248.
    • (2007) Journal of Applied Physiology , vol.102 , pp. 241-248
    • Nakamura, A.1    Zhang, W.2    Yanagisawa, M.3    Fukuda, Y.4    Kuwaki, T.5
  • 78
    • 79251526911 scopus 로고    scopus 로고
    • Distinguished lecture: Central chemoreception: Then ... and now
    • Nattie E., Comroe Julius H. distinguished lecture: Central chemoreception: Then ... and now. Journal of Applied Physiology 2011, 110:1-8.
    • (2011) Journal of Applied Physiology , vol.110 , pp. 1-8
    • Nattie, E.1    Comroe, J.H.2
  • 79
    • 66149145268 scopus 로고    scopus 로고
    • Central chemoreception is a complex system function that involves multiple brain stem sites
    • Nattie E., Li A. Central chemoreception is a complex system function that involves multiple brain stem sites. Journal of Applied Physiology 2009, 106:1464-1466.
    • (2009) Journal of Applied Physiology , vol.106 , pp. 1464-1466
    • Nattie, E.1    Li, A.2
  • 80
    • 77951959293 scopus 로고    scopus 로고
    • Central chemoreception in wakefulness and sleep: Evidence for a distributed network and a role for orexin
    • Nattie E., Li A. Central chemoreception in wakefulness and sleep: Evidence for a distributed network and a role for orexin. Journal of Applied Physiology 2010, 108:1417-1424.
    • (2010) Journal of Applied Physiology , vol.108 , pp. 1417-1424
    • Nattie, E.1    Li, A.2
  • 81
    • 34547619452 scopus 로고    scopus 로고
    • A comparative analysis of the distribution of immunoreactive orexin A and B in the brains of nocturnal and diurnal rodents
    • Nixon J.P., Smale L. A comparative analysis of the distribution of immunoreactive orexin A and B in the brains of nocturnal and diurnal rodents. Behavioral and Brain Functions 2007, 3:28.
    • (2007) Behavioral and Brain Functions , vol.3 , pp. 28
    • Nixon, J.P.1    Smale, L.2
  • 83
    • 70450191682 scopus 로고    scopus 로고
    • The mechanism of dead-in-bed syndrome and other sudden unexplained nocturnal deaths
    • Parekh B. The mechanism of dead-in-bed syndrome and other sudden unexplained nocturnal deaths. Current Diabetes Reviews 2009, 5:210-215.
    • (2009) Current Diabetes Reviews , vol.5 , pp. 210-215
    • Parekh, B.1
  • 84
    • 68349105188 scopus 로고    scopus 로고
    • Mechanisms of the blunting of the sympatho-adrenal response: A theory
    • Parekh B. Mechanisms of the blunting of the sympatho-adrenal response: A theory. Current Diabetes Reviews 2009, 5:79-91.
    • (2009) Current Diabetes Reviews , vol.5 , pp. 79-91
    • Parekh, B.1
  • 85
    • 0033826856 scopus 로고    scopus 로고
    • A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
    • Peyron C., Faraco J., Rogers W., Ripley B., Overeem S., Charnay Y., et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nature Medicine 2000, 6:991-997.
    • (2000) Nature Medicine , vol.6 , pp. 991-997
    • Peyron, C.1    Faraco, J.2    Rogers, W.3    Ripley, B.4    Overeem, S.5    Charnay, Y.6
  • 88
    • 79960937702 scopus 로고    scopus 로고
    • Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition
    • Ray R.S., Corcoran A.E., Brust R.D., Kim J.C., Richerson G.B., Nattie E., et al. Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition. Science 2011, 333:637-642.
    • (2011) Science , vol.333 , pp. 637-642
    • Ray, R.S.1    Corcoran, A.E.2    Brust, R.D.3    Kim, J.C.4    Richerson, G.B.5    Nattie, E.6
  • 89
    • 2642547405 scopus 로고    scopus 로고
    • Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis
    • Richerson G.B. Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nature Reviews. Neuroscience 2004, 5:449-461.
    • (2004) Nature Reviews. Neuroscience , vol.5 , pp. 449-461
    • Richerson, G.B.1
  • 90
    • 48249109864 scopus 로고    scopus 로고
    • Orexin receptor antagonists: Medicinal chemistry and therapeutic potential
    • Roecker A.J., Coleman P.J. Orexin receptor antagonists: Medicinal chemistry and therapeutic potential. Current Topics in Medicinal Chemistry 2008, 8:977-987.
    • (2008) Current Topics in Medicinal Chemistry , vol.8 , pp. 977-987
    • Roecker, A.J.1    Coleman, P.J.2
  • 91
    • 79958694833 scopus 로고    scopus 로고
    • The role of orexin-1 receptors in physiologic responses evoked by microinjection of PgE2 or muscimol into the medial preoptic area
    • Rusyniak D.E., Zaretsky D.V., Zaretskaia M.V., Dimicco J.A. The role of orexin-1 receptors in physiologic responses evoked by microinjection of PgE2 or muscimol into the medial preoptic area. Neuroscience Letters 2011, 498:162-166.
    • (2011) Neuroscience Letters , vol.498 , pp. 162-166
    • Rusyniak, D.E.1    Zaretsky, D.V.2    Zaretskaia, M.V.3    Dimicco, J.A.4
  • 92
    • 0037067003 scopus 로고    scopus 로고
    • Roles of orexins in regulation of feeding and wakefulness
    • Sakurai T. Roles of orexins in regulation of feeding and wakefulness. Neuroreport 2002, 13:987-995.
    • (2002) Neuroreport , vol.13 , pp. 987-995
    • Sakurai, T.1
  • 94
    • 20244380014 scopus 로고    scopus 로고
    • Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
    • Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., et al. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998, 92:573-585.
    • (1998) Cell , vol.92 , pp. 573-585
    • Sakurai, T.1    Amemiya, A.2    Ishii, M.3    Matsuzaki, I.4    Chemelli, R.M.5    Tanaka, H.6
  • 97
    • 79251497363 scopus 로고    scopus 로고
    • Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex
    • Shahid I.Z., Rahman A.A., Pilowsky P.M. Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex. British Journal of Pharmacology 2011, 162:961-973.
    • (2011) British Journal of Pharmacology , vol.162 , pp. 961-973
    • Shahid, I.Z.1    Rahman, A.A.2    Pilowsky, P.M.3
  • 100
    • 0037144189 scopus 로고    scopus 로고
    • Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure
    • Smith P.M., Connolly B.C., Ferguson A.V. Microinjection of orexin into the rat nucleus tractus solitarius causes increases in blood pressure. Brain Research 2002, 950:261-267.
    • (2002) Brain Research , vol.950 , pp. 261-267
    • Smith, P.M.1    Connolly, B.C.2    Ferguson, A.V.3
  • 102
  • 103
    • 79956083355 scopus 로고    scopus 로고
    • Diaphragm long-term facilitation following acute intermittent hypoxia during wakefulness and sleep
    • Terada J., Mitchell G.S. Diaphragm long-term facilitation following acute intermittent hypoxia during wakefulness and sleep. Journal of Applied Physiology 2011, 110:1299-1310.
    • (2011) Journal of Applied Physiology , vol.110 , pp. 1299-1310
    • Terada, J.1    Mitchell, G.S.2
  • 104
    • 38949190950 scopus 로고    scopus 로고
    • Ventilatory long-term facilitation in mice can be observed during both sleep and wake periods and depends on orexin
    • Terada J., Nakamura A., Zhang W., Yanagisawa M., Kuriyama T., Fukuda Y., et al. Ventilatory long-term facilitation in mice can be observed during both sleep and wake periods and depends on orexin. Journal of Applied Physiology 2008, 104:499-507.
    • (2008) Journal of Applied Physiology , vol.104 , pp. 499-507
    • Terada, J.1    Nakamura, A.2    Zhang, W.3    Yanagisawa, M.4    Kuriyama, T.5    Fukuda, Y.6
  • 107
    • 67649448978 scopus 로고    scopus 로고
    • Orexin/Hypocretin: A neuropeptide at the interface of sleep, energy homeostasis, and reward system
    • Tsujino N., Sakurai T. Orexin/Hypocretin: A neuropeptide at the interface of sleep, energy homeostasis, and reward system. Pharmacological Reviews 2009, 61:162-176.
    • (2009) Pharmacological Reviews , vol.61 , pp. 162-176
    • Tsujino, N.1    Sakurai, T.2
  • 113
    • 21844444542 scopus 로고    scopus 로고
    • Respiratory and cardiovascular actions of orexin-A in mice
    • Zhang W., Fukuda Y., Kuwaki T. Respiratory and cardiovascular actions of orexin-A in mice. Neuroscience Letters 2005, 385:131-136.
    • (2005) Neuroscience Letters , vol.385 , pp. 131-136
    • Zhang, W.1    Fukuda, Y.2    Kuwaki, T.3
  • 115
    • 33744523416 scopus 로고    scopus 로고
    • Multiple components of the defense response depend on orexin: Evidence from orexin knockout mice and orexin neuron-ablated mice
    • Zhang W., Shimoyama M., Fukuda Y., Kuwaki T. Multiple components of the defense response depend on orexin: Evidence from orexin knockout mice and orexin neuron-ablated mice. Autonomic Neuroscience: Basic & Clinical 2006, 126-127:139-145.
    • (2006) Autonomic Neuroscience: Basic & Clinical , pp. 139-145
    • Zhang, W.1    Shimoyama, M.2    Fukuda, Y.3    Kuwaki, T.4
  • 116
    • 61849174758 scopus 로고    scopus 로고
    • Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis
    • Zhang W., Zhang N., Sakurai T., Kuwaki T. Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis. Brain Research 2009, 1262:25-37.
    • (2009) Brain Research , vol.1262 , pp. 25-37
    • Zhang, W.1    Zhang, N.2    Sakurai, T.3    Kuwaki, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.