The role of orexin-1 receptors in physiologic responses evoked by microinjection of PgE2 or muscimol into the medial preoptic area

Neuroscience Letters

Volumn 498, Issue 2, 2011, Pages 162-166

  Rusyniak, Daniel E ^a   Zaretsky, Dmitry V ^a   Zaretskaia, Maria V ^a   DiMicco, Joseph A ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypothalamus; Microinjection; Muscimol; Orexin; Prostaglandin E2

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; MUSCIMOL; OREXIN 1 RECEPTOR; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BODY TEMPERATURE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DRUG EFFECT; EVOKED RESPONSE; HEART RATE; LOCOMOTION; MALE; MEDIAL PREOPTIC AREA; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BENZOXAZOLES; BLOOD PRESSURE; BODY TEMPERATURE REGULATION; DINOPROSTONE; HEART RATE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICROINJECTIONS; MUSCIMOL; NEUROPEPTIDES; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; UREA;

EID: 79958694833     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.05.006     Document Type: Article

References (38)

1. Boulant J.A. Role of the preoptic-anterior hypothalamus in thermoregulation and fever. Clin. Infect. Dis. 2000, 31:S157-S161.
2. Cerri M., Morrison S.F. Activation of lateral hypothalamic neurons stimulates brown adipose tissue thermogenesis. Neuroscience 2005, 135:627-638.
3. de Lecea L., Kilduff T.S., Peyron C., Gao X.-B., Foye P.E., Danielson P.E., Fukuhara C., Battenberg E.L.F., Gautvik V.T., Bartlett F.S., Frankel W.N., van den Pol A.N., Bloom F.E., Gautvik K.M., Sutcliffe J.G. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:322-327.
4. Gaykema R.P.A., Goehler L.E. Lipopolysaccharide challenge-induced suppression of Fos in hypothalamic orexin neurons: their potential role in sickness behavior. Brain. Behav. Immun. 2009, 23:926-930.
5. Girardier L., Clark M.G., Seydoux J. Thermogenesis associated with spontaneous activity: an important component of thermoregulatory needs in rats. J. Physiol. 1995, 488(Pt 3):779-787.
6. Hunt J.L., Zaretsky D.V., Sarkar S., Dimicco J.A. Dorsomedial hypothalamus mediates autonomic, neuroendocrine, and locomotor responses evoked from the medial preoptic area. Am. J. Physiol. 2010, 298:R130-R140.
7. Ishiwata T., Saito T., Hasegawa H., Yazawa T., Kotani Y., Otokawa M., Aihara Y. Changes of body temperature and thermoregulatory responses of freely moving rats during GABAergic pharmacological stimulation to the preoptic area and anterior hypothalamus in several ambient temperatures. Brain Res. 2005, 1048:32-40.
8. Jones D.N.C., Gartlon J., Parker F., Taylor S.G., Routledge C., Hemmati P., Munton R.P., Ashmeade T.E., Hatcher J.P., Johns A., Porter R.A., Hagan J.J., Hunter A.J., Upton N. Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity. Psychopharmacology (Berl). 2001, 153:210-218.
9. Konsman J.P., Parnet P., Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci. 2002, 25:154-159.
10. Kozak W., Conn C.A., Kluger M.J. Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice. Am. J. Physiol. 1994, 266:R125-135.
11. Kuru M., Ueta Y., Serino R., Nakazato M., Yamamoto Y., Shibuya I., Yamashita H. Centrally administered orexin/hypocretin activates HPA axis in rats. Neuroreport 2000, 11:1977-1980.
12. Monda M., Viggiano A., Mondola P., De Luca V. Inhibition of prostaglandin synthesis reduces hyperthermic reactions induced by hypocretin-1/orexin A. Brain Res. 2001, 909:68-74.
13. Monda M., Viggiano A., Viggiano A., Viggiano E., Messina G., Tafuri D., De Luca V. Sympathetic and hyperthermic reactions by orexin A: role of cerebral catecholaminergic neurons. Regul. Pept. 2007, 139:39-44.
14. Monda M., Viggiano A.N., Viggiano A., Viggiano E., Lanza A., De Luca V. Hyperthermic reactions induced by orexin A: role of the ventromedial hypothalamus. Eur. J. Neurosci. 2005, 22:1169-1175.
15. Morrison S.F., Nakamura K., Madden C.J. Central control of thermogenesis in mammals. Exp. Physiol. 2008, 93:773-797.
16. Nakamura K., Morrison S.F. Central efferent pathways mediating skin cooling-evoked sympathetic thermogenesis in brown adipose tissue. Am. J. Physiol. 2007, 292:R127-R136.
17. Nakamura T., Uramura K., Nambu T., Yada T., Goto K., Yanagisawa M., Sakurai T. Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system. Brain Res. 2000, 873:181-187.
18. Nakamura Y., Nakamura K., Matsumura K., Kobayashi S., Kaneko T., Morrison S.F. Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus. Eur. J. Neurosci. 2005, 22:3137-3146.
19. Osaka T. Blockade of prostaglandin E2-induced thermogenesis by unilateral microinjection of GABAA receptor antagonist into the preoptic area. Brain Res. 2008, 1230:107-114.
20. Osaka T. Cold-induced thermogenesis mediated by GABA in the preoptic area of anesthetized rats. Am. J. Physiol. 2004, 287:R306-R313.
21. Osaka T. Lipopolysaccharide-induced thermogenesis mediated by GABA in the preoptic area of anesthetized rats. J. Therm. Biol. 2006, 31:229-234.
22. Osaka T. Prostaglandin E2 fever mediated by inhibition of the GABAergic transmission in the region immediately adjacent to the organum vasculosum of the lamina terminalis. Pflugers Arch. 2008, 456:837-846.
23. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 1998, Academic Press, New York.
24. Russell S.H., Small C.J., Dakin C.L., Abbott C.R., Morgan D.G., Ghatei M.A., Bloom S.R. The central effects of orexin-A in the hypothalamic-pituitary-adrenal axis in vivo and in vitro in male rats. J. Neuroendocrinol. 2001, 13:561-566.
25. Rusyniak D.E., Zaretskaia M.V., Zaretsky D.V., DiMicco J.A. 3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors. J. Pharmacol. Exp. Ther. 2007, 323:477-487.
26. Rusyniak D.E., Zaretskaia M.V., Zaretsky D.V., DiMicco J.A. Microinjection of muscimol into the dorsomedial hypothalamus suppresses MDMA-evoked sympathetic and behavioral responses. Brain Res. 2008, 1226:116-123.
27. Sakurai T., Nagata R., Yamanaka A., Kawamura H., Tsujino N., Muraki Y., Kageyama H., Kunita S., Takahashi S., Goto K., Koyama Y., Shioda S., Yanagisawa M. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron 2005, 46:297-308.
28. Samson W.K., Bagley S.L., Ferguson A.V., White M.M. Hypocretin/orexin type 1 receptor in brain: role in cardiovascular control and the neuroendocrine response to immobilization stress. Am. J. Physiol. 2007, 292:R382-R387.
29. Samson W.K., Bagley S.L., Ferguson A.V., White M.M. Orexin receptor subtype activation and locomotor behaviour in the rat. Acta Physiol. 2010, 198:313-324.
30. Samson W.K., Gosnell B., Chang J.K., Resch Z.T., Murphy T.C. Cardiovascular regulatory actions of the hypocretins in brain. Brain Res. 1999, 831:248-253.
31. Satoh S., Matsumura H., Fujioka A., Nakajima T., Kanbayashi T., Nishino S., Shigeyoshi Y., Yoneda H. FOS expression in orexin neurons following muscimol perfusion of preoptic area. Neuroreport 2004, 15:1127-1131.
32. Sehic E., Székely M., Ungar A.L., Oladehin A., Blatteis C.M. Hypothalamic prostaglandin E2 during lipopolysaccharide-induced fever in guinea pigs. Brain Res. Bull. 1996, 39:391-399.
33. Shirasaka T., Nakazato M., Matsukura S., Takasaki M., Kannan H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am. J. Physiol. 1999, 277:R1780-1785.
34. Yoshida K., McCormack S., España R.A., Crocker A., Scammell T.E. Afferents to the orexin neurons of the rat brain. J. Comp. Neurol. 2006, 494:845-861.
35. Yoshimichi G., Yoshimatsu H., Masaki T., Sakata T. Orexin-A regulates body temperature in coordination with arousal status. Exp. Biol. Med. 2001, 226:468-476.
36. Zaretskaia M.V., Zaretsky D.V., DiMicco J.A. Role of the dorsomedial hypothalamus in thermogenesis and tachycardia caused by microinjection of prostaglandin E2 into the preoptic area in anesthetized rats. Neurosci. Lett. 2003, 340:1-4.
37. Zaretskaia M.V., Zaretsky D.V., Shekhar A., DiMicco J.A. Chemical stimulation of the dorsomedial hypothalamus evokes non-shivering thermogenesis in anesthetized rats. Brain Res. 2002, 928:113-125.
38. Zaretsky D.V., Hunt J.L., Zaretskaia M.V., DiMicco J.A. Microinjection of prostaglandin E2 and muscimol into the preoptic area in conscious rats: comparison of effects on plasma adrenocorticotrophic hormone (ACTH), body temperature, locomotor activity, and cardiovascular function. Neurosci. Lett. 2006, 397:291-296.