Orexins: A role in medullary sympathetic outflow

Regulatory Peptides

Volumn 96, Issue 1-2, 2000, Pages 65-70

  Dun, Nae J ^a   Le Dun,, Siok ^a   Chen, Chiung Tong ^a   Hwang, Ling Ling ^a   Kwok, Ernest H ^a   Chang, Jaw Kang ^b  

^a East Tennessee State University   (United States)

^b PHOENIX PHARMACEUTICALS INC   (United States)

Author keywords

Fos; Hypertension; Medulla; Obesity; Rostral ventrolateral medulla; Sympathetic preganglionic neurons

Indexed keywords

OREXIN A; OREXIN B;

ADRENERGIC NERVE CELL; CONFERENCE PAPER; ENERGY METABOLISM; FOOD INTAKE; HYPOTHALAMUS NUCLEUS; MEDULLA OBLONGATA; NERVE CONDUCTION; NONHUMAN; OBESITY; PRESSOR RESPONSE; PRIORITY JOURNAL; SPINAL CORD; SYMPATHETIC TONE;

ANIMALS; BLOOD PRESSURE; CARRIER PROTEINS; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NEURONS; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-FOS; SYMPATHETIC NERVOUS SYSTEM; UP-REGULATION;

EID: 0034704435     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(00)00202-0     Document Type: Conference Paper

References (26)

1. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
2. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
3. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation
4. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
5. Orexin A-like immunoreactivity in the rat brain
6. Neurons containing hypocretin (orexin) project to multiple neuronal systems
7. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems
8. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord
9. Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord
10. Hypothalamic orexin A-immunoreactive neurons project to the rat dorsal medulla
11. Rostral ventrolateral medulla: selective projections to the thoracic autonomic cell column from the region containing Cl adrenaline neurons
12. Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rat
13. Cardiovascular regulatory actions of the hypocretins in brain
14. Sympathetic and cardiovascular actions of orexins in conscious rats
15. GABA- and glycine-mediated inhibitory postsynaptic potentials in neonatal rat rostral ventrolateral medulla neurons in vitro
16. 5-HT modulates multiple conductances in immature rat rostral ventrolateral medulla neurones in vitro
17. Orexin A activates locus coeruleus cell firing and increases arousal in the rat
18. Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalalmic peptide, hypocretin/orexin
19. Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR
20. Hemorrhage induces Fos immunoreactivity in rat medullary catecholaminergic neurons
21. c-Fos expression as a marker of central cardiovascular neurons
22. The lateral hypothalamic area revisited: ingestive behavior
23. Distribution of orexin receptor mRNA in the rat brain
24. The hypocretins/orexins: novel hypothalamic neuropeptides involved in different physiological systems
25. Orexins and orexin receptors: implication in feeding behavior
26. Neural mechanisms in human obesity-related hypertension