Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle

Journal of Physiology

Volumn 588, Issue 15, 2010, Pages 2935-2944

  Li, Aihua ^a   Nattie, Eugene ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; ((2R) 2 ((1S) 6,7 DIMETHOXY 1 (2 (4 TRIFLUOROMETHYLPHENYL) ETHYL) 3,4 DIHYDRO 1H ISOQUINOLIN 2 YL) N METHYL 2 PHENYLACETAMIDE); ((2R)-2-((1S)-6,7-DIMETHOXY-1-(2-(4-TRIFLUOROMETHYLPHENYL)-ETHYL)-3,4-DIHYDRO-1H-ISOQUINOLIN-2-YL)-N-METHYL-2-PHENYLACETAMIDE); ACETAMIDE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; ISOQUINOLINE DERIVATIVE; NEUROPEPTIDE RECEPTOR; OREXIN RECEPTORS;

ALERTNESS; ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CHEMORECEPTOR; CIRCADIAN RHYTHM; CONTROLLED STUDY; LIGHT DARK CYCLE; MALE; METABOLIC RATE; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING; REM SLEEP; WAKEFULNESS; ANIMAL; BRAIN; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACETAMIDES; ANIMALS; BRAIN; CHEMORECEPTOR CELLS; CIRCADIAN RHYTHM; ISOQUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; WAKEFULNESS;

EID: 79251504455     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.191288     Document Type: Article

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