Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 334, Issue 2, 2010, Pages 522-529

  Huang, Shang Cheng ^a   Dai, Yu Wen E ^a   Lee, Yen Hsien ^a   Chiou, Lih Chu ^b   Hwang, Ling Ling ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

(2) 1 (3,4 DIHYDRO 6,7 DIMETHOXY 2(1H) ISOQUINOLINYL) 3,3 DIMETHYL 2 [(4 PYRIDINYLMETHYL)AMINO] 1-BUTANONE HYDROCHLORIDE; 1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; BLOCKING AGENT; OREXIN; OREXIN 2 RECEPTOR; OREXIN A; OREXIN B; TCS OX2 29; TETRODOTOXIN; UNCLASSIFIED DRUG;

ARTERIAL PRESSURE; ARTICLE; BRAIN NERVE CELL; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DEPOLARIZATION; ELECTROPHYSIOLOGY; FEMALE; HEART RATE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; ZONA INCERTA;

ACTION POTENTIALS; ANIMALS; BLOOD PRESSURE; FEMALE; HEART RATE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEDULLA OBLONGATA; NEURONS; NEUROPEPTIDES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE;

EID: 77954944602     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.167791     Document Type: Article

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