The endogenous opioid system in cocaine addiction: What lessons have opioid peptide and receptor knockout mice taught us?

British Journal of Pharmacology

Volumn 166, Issue 7, 2012, Pages 1993-2014

  Yoo, Ji Hoon ^a   Kitchen, Ian ^a   Bailey, Alexis ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

addiction; opioid receptors (MOPr); cocaine; opioid receptors (KOPr); knockout (KO); opioid; pharmacotherapy; preprodynorphin (PDYN); relapse

Indexed keywords

ACETYLCYSTEINE; BETA ENDORPHIN; BUPRENORPHINE; COCAINE; DELTA OPIATE RECEPTOR; DOPAMINE; ENDORPHIN; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; MESSENGER RNA; MU OPIATE RECEPTOR; NALTREXONE; OPIATE RECEPTOR; PREPRODYNORPHIN; PREPROENKEPHALIN; PROOPIOMELANOCORTIN;

ABSENCE OF SIDE EFFECTS; BIPOLAR DISORDER; BRAIN LEVEL; BRAIN REGION; COCAINE DEPENDENCE; DOPAMINERGIC SYSTEM; DRUG EFFICACY; DRUG EXPOSURE; GENE EXPRESSION REGULATION; GENE INACTIVATION; HEROIN DEPENDENCE; HUMAN; KNOCKOUT MOUSE; LONG TERM EXPOSURE; NEUROCHEMISTRY; NEUROMODULATION; NEUROPATHOLOGY; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RELAPSE; REVIEW; REWARD; TREATMENT OUTCOME; WITHDRAWAL SYNDROME;

EID: 84863661820     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01952.x     Document Type: Review

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