Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area

Alcoholism: Clinical and Experimental Research

Volumn 33, Issue 6, 2009, Pages 1033-1043

  Jarjour, Samuel ^a,b   Bai, Li ^b   Gianoulakis, Christina ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

Author keywords

Endorphin; Alcohol; Dynorphin A1 8; In vivo microdialysis; Met enkephalin

Indexed keywords

ALCOHOL; BETA ENDORPHIN; DYNORPHIN[1-8]; METENKEPHALIN; OPIATE PEPTIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; DOSE RESPONSE; MALE; MESENCEPHALON; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; REINFORCEMENT; VENTRAL TEGMENTUM;

ALCOHOLISM; ANIMALS; BETA-ENDORPHIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNORPHINS; ENKEPHALIN, METHIONINE; ETHANOL; INJECTIONS, INTRAPERITONEAL; MALE; MESENCEPHALON; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; VENTRAL TEGMENTAL AREA;

EID: 66549117005     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.00924.x     Document Type: Article

References (82)

1. Akil H, Bronstein D, Mansour A (1988) Overview of the endogenous opioid systems: anatomical, biochemical, and functional issues. in Endorphins, Opiates and Biochemical Processes (Rodgers RJ, Cooper SJ eds), pp 1 23. John Wiley & Sons Ltd., Chichester.
2. Akil H, Owens C, Gutstein H, Taylor L, Curran E, Watson SJ (1998) Endogenous opioids: overview and current issues. Drug Alcohol Depend 51 : 127 140. (Pubitemid 28353761)
3. Akil H, Watson SJ, Young E, Lewis ME, Khachaturian H, Walker JM (1984) Endogenous opioids: biology and function. Annu Rev Neurosci 7 : 223 255. (Pubitemid 14155298)
4. Altshuler HL, Phillips PE, Feinhandler DA (1980) Iteration of ethanol self-administration by naltrexone. Life Sci 26 : 679 688.
5. Angelogianni P, Gianoulakis C (1993) Chronic ethanol increases proopiomelanocortin gene expression in the hypothalamus. Neuroendocrinology 57 : 106 114. (Pubitemid 23091894)
6. Bals-Kubik R, Herz A, Shippenberg TS (1989) Evidence that the aversive effects of opioid antagonists and κ-agonists are centrally mediated. Psychopharmacology (Berl) 98 : 203 206. (Pubitemid 19137732)
7. Bechtholt AJ, Cunningham CL (2005) Ethanol-induced conditioned place preference is expressed through a ventral tegmental area dependent mechanism. Behav Neurosc 119 : 213 223. (Pubitemid 40279511)
8. Blanchard BA, Steindorf S, Wang S, Glick SD (1993) Sex differences in ethanol-induced dopamine release in nucleus accumbens and in ethanol consumption in rats. Alcohol Clin Exp Res 17 : 968 973. (Pubitemid 24000512)
9. Bronstein DM, Schafer MK, Watson SJ, Akil H (1992) Evidence that beta-endorphinis synthesized in cells in the nucleus tractus solitarious: detection of POMC mRNA. Brain Res 587 : 269 275.
10. Charnes ME (1989) Ethanol and opioid receptor signalling. Experientia 45 : 518 528.
11. Chefer VI, Czyzyk T, Bolan EA, Moron J, Pintar JE, Shippenberg TS (2005) Endogenous κ-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine. J Neurosci 25 : 5029 5037. (Pubitemid 40712846)
12. Dalman FC, O'Malley KL (1999) κ-opioid tolerance and dependence in cultures of dopaminergic midbrain neurons. J Neurosci 19 : 5750 5757. (Pubitemid 29327912)
13. de Waele J-P, Gianoulakis C (1993) Effects of single and repeated exposure to ethanol on hypothalamic β-endorphin and CRH release by the C57BL/6 and DBA/2 strains of mice. Neuroendocrinology 57 : 700 709. (Pubitemid 23223637)
14. de Waele J-P, Gianoulakis C (1994) Enhanced activity of the brain β-endorphin system by free-choice ethanol drinking in C57BW6 but not DBA/2 mice. Eur J Pharmacol 258 : 119 129. (Pubitemid 24174994)
15. de Waele J-P, Papachristou D, Gianoulakis C (1992) The alcohol-preferring C57BL/6 mice present an enhanced sensitivity of the hypothalamic β-endorphin system to ethanol than the alcohol-avoiding DBA/2 mice. J Pharmacol Exp Ther 261 : 788 794.
16. Di Chiara G, Imperato A (1985) Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely-moving rats. Eur J Pharmacol 115 : 131 132. (Pubitemid 16233374)
17. Finley JCW, Maderdrut JL, Petrusz P (1981) The immunocytochemical localization of enkephalin in the central nervous system of the rat. J Comp Neurol 198 : 541 565. (Pubitemid 11109552)
18. Ford CP, Mark GP, Williams JT (2006) Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J Neurosci 26 : 2788 2797. (Pubitemid 43357862)
19. Froehlich JC, Harts J, Lumeng L, Li T-K (1990) Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference. Pharmacol Biochem Behav 35 : 385 390. (Pubitemid 20075583)
20. Froehlich JC, Zweifel M, Harts J, Lumeng L, Li TK (1991) Importance of δ opioid receptors in maintaining high alcohol drinking. Psychopharmacology (Berl) 103 : 467 472.
21. Gee CE, Chen CL, Roberts JL, Thompson R, Watson SJ (1983) Identification of proopiomelanocortin neurons in rat hypothalamus by in situ cDNA-mRNA hybridization. Nature 306 : 374 376. (Pubitemid 14242747)
22. George SR, Rolan L, Lui A, Naranjo CA (1991) Endogenous opioids are involved in the genetically determined high preference for ethanol consumption. Alcohol Clin Exp Res 15 : 668 672.
23. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G (1985) Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348 : 201 203. (Pubitemid 16235764)
24. Gianoulakis C (1990) Characterization of the effects of acute ethanol administration on the release of endorphin peptides by the rat hypothalamus. Eur J Pharmacol 180 : 21 29. (Pubitemid 20140986)
25. Gianoulakis C (2004) Endogenous opioids and addiction to alcohol and other drugs of abuse. Curr Top Med Chem 4 : 39 50. (Pubitemid 38849357)
26. Gianoulakis C, Barcomb A (1987) Effect of acute ethanol in vivo and in vitro on the β-endorphin system in the rat. Life Sci 40 : 19 28. (Pubitemid 17226120)
27. Gianoulakis C, Gupta A (1986) Inbred strains of mice with variable sensitivity to ethanol exhibit differences in the content and processing of β-endorphin. Life Sci 39 : 2315 2325. (Pubitemid 17190201)
28. Heyser CJ, Roberts AJ, Schulteis G, Koob GF (1999) Central administration of an opiate antagonist decreases oral ethanol self-administration in rats. Alcohol Clin Exp Res 23 : 1468 1476. (Pubitemid 29468443)
29. Holter SM, Henniger MS, Lipkowski AW, Spanagel R (2000) κ-opioid receptors and relapse-like drinking in long-term ethanol-experienced rats. Psychopharmacology (Berl) 153 : 93 102. (Pubitemid 32127907)
30. Hubbell CL, Czirr SA, Hunter GA, Beaman CM, LeCann NC, Reid LD (1986) Consumption of ethanol solution is potentiated by morphine and attenuated by naloxone persistently across repeated daily administrations. Alcohol 3 : 39 54. (Pubitemid 16143338)
31. Hyytia P, Sinclair JD (1993) Responding for oral ethanol after naloxone treatment by alcohol-preferring AA rats. Alcohol Clin Exp Res 17 : 631 636. (Pubitemid 23178449)
32. Imperato A, Di Chiara G (1986) Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol. J Pharmacol Exp Ther 239 : 219 228. (Pubitemid 16006360)
33. June HL, McCane SM, Zink RW, Portoghese PS, Li TK, Froehlich JC (1999) The δ2-opioid receptor antagonist naltriben reduces motivated responding for ethanol. Psychopharmacology (Berl) 147 : 81 89. (Pubitemid 30010027)
34. Keith LD, Crabbe JC, Robertson LM, Kendall JW (1986) Ethanol-stimulated endorphin and corticotropin secretion in vitro. Brain Res 367 : 222 229. (Pubitemid 16011680)
35. Khachaturian H, Lewis ME, Schafer MK-H, Watson SJ (1985) Anatomy of the CNS opioid systems. Trends Neurosci 8 : 111 119. (Pubitemid 15116145)
36. Koenig HN, Olive MF (2002) Ethanol consumption patterns and conditioned place preference in mice lacking preproenkephalin. Neurosci Lett 325 : 75 78. (Pubitemid 34607198)
37. Kohl RR, Katner JS, Chernet E, McBride WJ (1998) Ethanol and negative feedback regulation of mesolimbic dopamine release in rats. Psychopharmacology (Berl) 139 : 79 85. (Pubitemid 28416885)
38. Krishnan-Sarin S, Wand GS, Li XW, Portoghese PS, Froehlich JC (1998) Effect of μ opioid receptor blockade on alcohol intake in rats bred for high alcohol drinking. Pharmacol Biochem Behav 59 : 627 635. (Pubitemid 28144202)
39. Lam MP, Marinelli PW, Bai L, Gianoulakis C (2008) Effects of acute ethanol on opioid peptide release in the central amygdale: an in vivo microdialysis study. Psychopharmacology 201 : 261 271.
40. Lê AD, Poulous CX, Quan B, Chow S (1993) The effects of selective blockade of δ and μ opiate receptors on ethanol consumption by C57BL/6 mice in a restricted access paradigm. Brain Res 630 : 330 332. (Pubitemid 23342856)
41. Li X-W, Li T-K, Froehlich JC (1998) Enhanced sensitivity of the nucleus accumbens proenkephalin system to alcohol in rats selectively bred for alcohol preference. Brain Res 794 : 35 47. (Pubitemid 28298863)
42. Lindholm S, Ploj K, Franck J, Nylander I (2000) Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain. Alcohol 22 : 165 171. (Pubitemid 32015909)
43. Lindholm S, Werme M, Brene S, Franck J (2001) The selective κ-opioid receptor agonist U50,488H attenuates voluntary ethanol intake in the rat. Behav Brain Res 120 : 137 146. (Pubitemid 32140981)
44. Lundquist F (1957) The determination of ethyl alcohol in blood and tissues, in Methods of Biochemical Analysis (Glick D ed.), pp 217 251. Interscience Publishers, New York.
45. Maidment NT, Evans CJ (1991) Measurement of extracellular neuropeptides in the brain: microdialysis linked to solid-phase radioimmunoassay with sub-femtomole limits of detection. in Microdialysis in the Neurosciences (Robinson TE, Justice JB Jr. eds), pp 275 302. Elsevier Science Publishers, Amsterdam.
46. Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ (1988) Anatomy of CNS opioid receptors. Trends Neurosci 11 : 308 314. (Pubitemid 18150893)
47. Marinelli PW, Bai L, Quirion R, Gianoulakis C (2005) A microdialysis profile of met-enkephalin release in the rat nucleus accumbens following alcohol administration. Alcohol Clin Exp Res 29 : 1821 1828. (Pubitemid 41579131)
48. Marinelli PW, Lam M, Bai L, Quirion R, Gianoulakis C (2006) A microdialysis profile of dynorphin A(1-8) release in the rat nucleus accumbens following alcohol administration. Alcohol Clin Exp Res 30 : 982 990. (Pubitemid 43823259)
49. Marinelli PW, Quirion R, Gianoulakis C (2003) A microdialysis profile of β-endorphin and catecholamines in the rat nucleus accumbens following alcohol administration. Psychopharmacology (Berl) 169 : 60 67. (Pubitemid 37088615)
50. Marinelli PW, Quirion R, Gianoulakis C (2004) An in vivo profile of β-endorphin release in the arcuate nucleus and nucleus accumbens following exposure to stress or alcohol. Neurosci 127 : 777 784. (Pubitemid 38993178)
51. Méndez M, Leriche M, Calva JC (2001) Acute ethanol administration differentially modulates μ opioid receptors in the rat mesoaccumbens and mesocortical pathways. Mol Brain Res 94 : 148 156. (Pubitemid 32964756)
52. Méndez M, Morales-Mulia M (2006) Ethanol exposure differentially alters pro-enkephalin mRNA expression in regions of the mesocorticolimbic system. Psychopharmacology (Berl) 189 : 117 124. (Pubitemid 44607265)
53. Middaugh LD, Kelley BM, Cuison ER Jr., Groseclose CH (1999) Naltrexone effects on ethanol reward and discrimination in C57BL/6 mice. Alcohol Clin Exp Res 23 : 456 464. (Pubitemid 29144839)
54. Mocsary Z, Bradberry CW (1996) Effect of ethanol on extracellular dopamine in nucleus accumbens: comparison between Lewis and Fischer 344 rat strains. Brain Res 706 : 194 198. (Pubitemid 26046717)
55. Mucha RF, Iversen SD (1984) Reinforcing properties of morphine and naloxone revealed by conditioned place preferences: a procedural examination. Psychopharmacology (Berl) 82 : 241 247. (Pubitemid 14184551)
56. Ng GYK, O'Dowd BF, George SR (1996) Genotypic differences in mesolimbic enkephalin gene expression in DBA/2J and C57BL/6J inbred mice. Eur J Pharmacol 311 : 45 52. (Pubitemid 26298498)
57. Nylander I, Hyytia P, Forsander O, Terenius L (1994) Differences between alcohol-preferring (AA) and alcohol-avoiding (ANA) rats in the prodynorphin and proenkephalin systems. Alcohol Clin Exp Res 18 : 1272 1279. (Pubitemid 24345544)
58. Olive MF, Koenig HN, Nannini MA, Hodge CW (2001) Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine and amphetamine. J Neurosci 21 : RC184.
59. Olson GA, Olson RD, Kastin AJ (1996) Endogenous opiates: 1995. Peptides 17 : 1421 1466. (Pubitemid 27016356)
60. Oswald LM, Wand GS (2004) Opioids and alcoholism. Physiol Behav 81 : 339 358. (Pubitemid 38670094)
61. Paxinos G, Watson C (1998) The Rat Brain in Stereotaxic Coordinates. 4th ed. Academic Press, San Diego.
62. Przewlocka B, Lason W, Przewlocki R (1994) Repeated ethanol differently affects opioid peptide biosynthesis in the rat pituitary. Neuroendocrinology 60 : 331 336. (Pubitemid 24260687)
63. Quirion R, Pert CB (1981) Dynorphins: similar relative potencies on μ, δ, and κ-opiate receptors. Eur J Pharmacol 76 : 467 468. (Pubitemid 12253551)
64. Rahman S, McBride WJ (2001) D1-D2 dopamine receptor interaction within the nucleus accumbens mediates long-loop negative feedback to the ventral tegmental area (VTA). J Neurochem 77 : 1248 1255. (Pubitemid 32523677)
65. Rasmussen DD, Boldt BM, Wilkinson CW, Mitton DR (2002) Chronic daily ethanol and withdrawal: forebrain pro-opiomelanocortin gene expression and implications for dependence, relapse, and deprivation effect. Alcohol Clin Exp Res 26 : 535 546. (Pubitemid 34408720)
66. Rasmussen DD, Bryant CA, Boldt BM, Colasurdo EA, Levin N, Wilkinson CW (1998) Acute alcohol effects on opiomelanocortinergic regulation. Alcohol Clin Exp Res 22 : 789 801. (Pubitemid 28292461)
67. Raynor K, Kong H, Chen Y, Yasuda K, Yu L, Bell GI, Reisine T (1994) Pharmacological characterization of the cloned κ-δ-and μ-opioid receptors. Mol Pharmacol 45 : 330 334.
68. van Ree JM, Smyth DG, Colpaert FC (1979) Dependence creating properties of lipotropin C-fragment (β-endorphin): evidence for its internal control of behavior. Life Sci 24 : 495 502. (Pubitemid 9123394)
69. Samson HH, Doyle TF (1985) Oral ethanol-self-administration in the rat: effect of naloxone. Pharmacol Biochem Behav 22 : 92 99.
70. Sar M, Stumpf WE, Miller RJ, Chang K-J, Cuatrecasas P (1978) Immunocytochemical localization of enkephalin in the rat brain and spinal cord. J Comp Neurol 182 : 17 38.
71. Schulz R, Wuster M, Duka T, Herz A (1980) Acute and chronic ethanol treatment changes endorphin levels in brain and pituitary. Psychopharmacology (Berl) 68 : 221 227. (Pubitemid 10124215)
72. Seizinger BR, Bovermann K, Maysinger D, Hollt V, Herz A (1983) Differential effects of acute and chronic ethanol treatment on particular opioid peptide systems in discrete regions of rat brain and pituitary. Pharmacol Biochem Behav 18 : 361 369.
73. Solinas M, Zangen A, Thiriet N, Goldberg SR (2004) β-Endorphin elevations in the ventral tegmental area regulate the discriminative effects of δ-9-tetrahydrocannabinol. Eur J Neurosci 10 : 3183 3192. (Pubitemid 38859535)
74. Stromberg MF, Casale M, Volpicelli JR, O'brien CP (1998) A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and β-funaltrexamine on ethanol consumption in the rat. Alcohol 15 : 281 289. (Pubitemid 28205097)
75. Tizabi Y, Copeland RL Jr., Louis VA, Taylor RE (2002) Effects of combined systemic alcohol and central nicotine administration into ventral tegmental area on dopamine release in the nucleus accumbens. Alcohol Clin Exp Res 26 : 394 399. (Pubitemid 34225846)
76. Van Wolfswinkel L, van Ree JM (1985) Effects of morphine and naloxone on thresholds of ventral tegmental electrical self stimulation. Naunyn Schmiedeberg's Arch Pharmacol 330 : 84 92. (Pubitemid 15045269)
77. Volpicelli JR, Davis MA, Olgin JE (1986) Naltrexone blocks the post-shock increase of ethanol consumption. Life Sci 38 : 841 847. (Pubitemid 16165575)
78. Watson SJ, Barchas JD, Li CH (1977) β-lipotropin: localization of cells and axons in rat brain by immunocytochemistry. Proc Natl Acad Sci U S A 74 : 5155 5158. (Pubitemid 8239065)
79. Yan Q-S (1999) Extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis. Alcohol 19 : 1 7. (Pubitemid 29415265)
80. Yim HJ, Robinson DL, White M, Jaworski JN, Randall PK, Lancaster FE, Gonzales RA (2000) Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. Alcohol Clin Exp Res 24 : 781 788. (Pubitemid 30421727)
81. Yoshida M, Yokoo H, Tanaka T, Mizoguchi K, Emoto H, Ishii H, Tanaka M (1993) Facilitatory modulation of mesolimbic dopamine neuronal activity by a mu-opioid agonist and nicotine as examined with in vivo microdialysis. Brain Res 624 : 277 280. (Pubitemid 23281829)
82. Zakarian S, Smyth DG (1982) Distribution of beta-endorphin-related peptides in rat pituitary and brain. Biochem J 202 : 561 571.