Downregulation of κ-opioid receptors in basolateral amygdala and septum of rats withdrawn for 14 days from an escalating dose "Binge" cocaine administration paradigm

Synapse

Volumn 61, Issue 10, 2007, Pages 820-826

  Bailey, Alexis ^a,b   Gianotti, Robert ^a   Ho, Ann ^a   Kreek, Mary J ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Escalating "binge" cocaine administration; Opioid receptor; Withdrawal

Indexed keywords

COCAINE; KAPPA OPIATE RECEPTOR; NALOXONE; OPIATE RECEPTOR;

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BRAIN; COCAINE DEPENDENCE; CONTROLLED STUDY; DYSPHORIA; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SEPTUM PELLUCIDUM; SEROTONINERGIC NERVE CELL;

AMYGDALA; ANALYSIS OF VARIANCE; ANIMALS; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; BENZOFURANS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE UPTAKE INHIBITORS; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; MALE; NEUROPROTECTIVE AGENTS; PYRROLIDINES; RATS; RATS, INBRED F344; RECEPTORS, OPIOID, KAPPA; SEPTUM OF BRAIN; TRITIUM;

EID: 34548257746     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20436     Document Type: Article

References (42)

1. Adams DH, Hanson GR, Keefe KA. 2003. Distinct effects of methamphetamine and cocaine on preprodynorphin messenger RNA in rat striatal patch and matrix. J Neurochem 84:87-93.
2. 2A receptor gene. J Neurosci 22:9210-9220.
3. Bailey A, Gianotti R, Kreek MJ. 2005. Persistent upregulation of μ-opioid but not adenosine receptors in brains of long term withdrawn escalating dose "binge" cocaine treated rats. Synapse 57:160-166.
4. Battaglia G, Sharkey J, Kuhar MJ, de Souza EB. 1991. Neuroanatomical specificity and time course of alterations in rat brain serotonergic pathways induced by NDMA (3,4-methylenedioxymethamphetamine): Assessment using autoradiography. Synapse 8:249-260.
5. Becker A, Grecksch G, Kraus J, Loh HH, Schroeder H, Hollt V. 2002. Rewarding effects of ethanol and cocaine in μ opioid receptor-deficient mice. Naunyn Schmiedebergs Arch Pharmacol 365:296-302.
6. Carboni E, Imperato A, Perezzani L, Di-Chiara G. 1989. Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats. Neuroscience 28:653-661.
7. Collins SL, Kunko PM, Ladenheim B, Cadet JL, Carroll FI, Izenwasser S. 2002. Chronic cocaine increases κ-opioid receptor density: lack of effect by selective dopamine uptake inhibitors. Synapse 45:153-158.
8. Crawford D, McDougall SA, Bolanos CA, Hall S, Berger SP. 1995. The effects of the κ agonist U-50,488 on cocaine-induced conditioned and unconditioned behaviors and Fos immunoreactivity. Psychopharmacology 120:392-399.
9. Di-Chiara G, Imperato A. 1988. Opposite effects of μ- and κ opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J Pharmacol Exp Ther 244:1067-1080.
10. Gawin F. 1991. Cocaine addiction: Psychology and neurophysiology. Science 251:1580-1586.
11. Hammer RP, Pires WS, Markou A, Koob GF. 1993. Withdrawal following cocaine self-administration decreases regional metabolic rate in critical brain regions. Synapse 14:73-80.
12. Hurd YL, Herkenham M. 1993. Molecular alterations in the neostriatum of human cocaine addicts. Synapse 13:357-369.
13. Hurd YL, Brown EE, Finlay JM, Fibiger HC, Gerfen CR. 1992. Cocaine self-administration differentially alters mRNA expression of striatal peptides. Mol Brain Res 13:165-170.
14. Kitchen I, Slowe S, Matthes H, Kieffer B. 1997. Quantitative autoradiographic mapping of μ, δ and κ opioid receptors in knockout mice lacking the μ-opioid receptor gene. Brain Res 778:73-88.
15. Kreek MJ, LaForge KS, Butelman E. 2002. Pharmacotherapy of addictions. Nat Rev 1:710-726.
16. Kuzmin AV, Semenova S, Gerrits MA, Zvartau EE, Van Ree JM. 1997. κ-Opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice. Eur J Pharmacol 321:265-271.
17. Liu-Chen LY. 2004. Agonist-induced regulation and trafficking of kappa opioid receptors. Life Sci 75:511-536.
18. Maisonneuve IM, Kreek MJ. 1994. Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study. J Pharmacol Exp Ther 268:916-921.
19. Maisonneuve IM, Ho A, Kreek MJ. 1995. Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: An in vivo microdialysis study. J Pharmacol Exp Ther 272:652-657.
20. McLaughlin DP, Marton-Popovici M, Chavjin C. 2003. κ-Opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. J Neurosci 23:5674-5683.
21. Paxinos G, Watson C. 1986. The rat brain in stereotaxic coordinates. San Diego, CA: Academic Press.
22. Pomperiani M, Palacios JM, Mengood G. 1994. Distribution of the serotin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors. Brain Res Mol Brain Res 23:163-178.
23. Rosin A, Kitchen I, Georgieva J. 2003. Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: An autoradiographyic study. Brain Res 978:1-13.
24. Schluger JH, Borg L, Ho A, Kreek MJ. 2001. Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction. Neuropsychopharmacology 24:568-575.
25. Sharpe LG, Pilotte NS, Shippenberg TS, Goodman CB, London ED. 2000. Autoradiographic evidence that prolonged withdrawal from intermittent cocaine reduces μ-opioid receptor expression in limbic regions of the rat brain. Synapse 37:292-297.
26. 3H]bremazocine binding in single and combinatorial opioid receptor knockout mice. Eur J Pharmacol 414:189-195.
27. Sivam SP. 1989. Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. J Pharmacol Exp Ther 250:818-824.
28. Smiley PL, Johnson M, Bush L, Gibb JW, Hanson GR. 1990. Effects of cocaine on extrapyramidal and limbic dynorphin systems. J Pharmacol Exp Ther 253:938-943.
29. Spanagel R, Herz A, Shippenberg TS. 1992. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci USA 89:2046-2050.
30. Spangler R, Unterwald EM, Kreek MJ. 1993. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Mol Brain Res 19:323-327.
31. 1 receptor in the rat nucleus accumbens. J Neurochem 87:1478-1484.
32. Turchan J, Przewlocka B, Lason W, Przewlocki R. 1998. Effects of repeated psychostimulant administration on the prodynorphin system activity and κ opioid receptor density in the rat brain. Neuroscience 85:1051-1059.
33. Turchan J, Przewlocka B, Toth G, Laso W, Borsodi A, Przewlocki R. 1999. The effect of repeated administration of morphine, cocaine and ethanol on μ and δ opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience 91:971-977.
34. Unterwald EM, Horne-King J, Kreek MJ. 1992. Chronic cocaine alters brain μ opioid receptors. Brain Res 584:314-318.
35. Unterwald EM, Rubenfeld JM, Kreek MJ. 1994. Repeated cocaine administration upregulates κ and μ, but not δ, opioid receptors. Neuroreport 5:1613-1616.
36. Werme M, Thoren P, Olson L, Brene S. 2000. Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen. Eur J Neurosci 12:2967-2974.
37. Wise RA. 1996. Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19:319-340.
38. Xi ZX, Ramamoorthy S, Baker DA, Shen H, Samuvel DJ, Kalivas PW. 2002. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. J Pharmacol Exp Ther 303:608-615.
39. Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW. 2003. GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. J Neurosci 23:3498-3505.
40. Zhang Y, Butelman E, Schlussman SD, Ho A, Kreek MJ. 2004a. Effect of the endogenous κ opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced preference in C57BL/6J mice. Psychopharmacology 172:422-429.
41. Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ. 2004b. Effect of the κ opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Neuropsychopharmacology 173:146-152.
42. Zhou Y, Bendor JT, Yuferov V, Schlussman SD, Ho A, Kreek MJ. 2005. Amygdalar vasopressin mRNA increases in acute cocaine withdrawal: evidence for opioid receptor modulation. Neuroscience 134:1391-1397.