Decrease of D2 receptor binding but increase in D 2-stimulated G-protein activation, dopamine transporter binding and behavioural sensitization in brains of mice treated with a chronic escalating dose 'binge' cocaine administration paradigm

European Journal of Neuroscience

Volumn 28, Issue 4, 2008, Pages 759-770

  Bailey, A ^a   Metaxas, A ^a   Yoo, J H ^a   McGee, T ^a   Kitchen, I ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

35S GTP S; Autoradiography; Locomotion; Stereotypy

Indexed keywords

COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); SODIUM CHLORIDE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; DOPAMINE UPTAKE INHIBITOR; MAZINDOL; QUINELORANE; QUINOLINE DERIVATIVE; RACLOPRIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BEHAVIOR; BRAIN; C57BL 6 MOUSE; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; DENSITY; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG DEPENDENCE; DRUG DOSE ESCALATION; DRUG EFFECT; DRUG USE; INJECTION; LOCOMOTION; MALE; MOUSE; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE ANALYSIS; RAT; SCORING SYSTEM; SENSITIZATION; STEREOTYPY; ADDICTION; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; HUMAN; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MALE; MAZINDOL; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PROTEIN BINDING; QUINOLINES; RACLOPRIDE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SUBSTANCE-RELATED DISORDERS;

EID: 49249132504     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06369.x     Document Type: Article

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