Persistent upregulation of μ-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose "binge" cocaine-treated rats

Synapse

Volumn 57, Issue 3, 2005, Pages 160-166

  Bailey, Alexis ^a,b   Gianotti, Robert ^a   Ho, Ann ^a   Kreek, Mary Jeanne ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

Opioid receptor; Escalating "binge" cocaine administration; Withdrawal

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE RECEPTOR; COCAINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MU OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CINGULATE GYRUS; COCAINE DEPENDENCE; CONTROLLED STUDY; FRONTAL CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; RECEPTOR BINDING; RECEPTOR UPREGULATION;

ADENOSINE; ANALGESICS, OPIOID; ANIMALS; AUTORADIOGRAPHY; BEHAVIOR, ANIMAL; BRAIN; BRAIN MAPPING; COCAINE; DOPAMINE UPTAKE INHIBITORS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; MALE; PHENETHYLAMINES; PROTEIN BINDING; RATS; RATS, INBRED F344; RECEPTORS, OPIOID, MU; RECEPTORS, PURINERGIC P1; SUBSTANCE WITHDRAWAL SYNDROME; TRITIUM; UP-REGULATION; XANTHINES;

EID: 22544472116     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.20168     Document Type: Article

References (47)

1. Adams DH, Hanson GR, Keefe KA. 2003. Distinct effects of methamphetamine and cocaine on preprodynorphin messenger RNA in rat striatal patch and matrix. J Neurochem 84:87-93.
2. 2A receptor gene. J Neurosci 22:9210-9220.
3. Bailey A, Matthes H, Kieffer B, Slowe S, Hourani SM, Kitchen I. 2002b. Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains and spinal cords of mice deficient in the μ-opioid receptor gene. Brain Res 943:68-79.
4. 2A adenosine receptor knockout mice. J Neurochem 88:827-834.
5. Bailey A, Yuferov V, Bendor J, Schlussman SD, Zhou Y, Ho A, Kreek MJ. 2005. Immediate withdrawal from chronic "binge" cocaine administartion increases μ-opioid receptor mRNA levels in rat frontal cortex. Brain Res Mol Brain Res 137:258-262.
6. Baldo BA, Koob GF, Markou A. 1999. Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats. J Neurosci 19:11017-11026.
7. Becker A, Grecksch G, Kraus J, Loh HH, Schroeder H, Hollt V. 2002. Rewarding effects of ethanol and cocaine in μ opioid receptor-deficient mice. Naunyn Schmiedebergs Arch Pharmacol 365:296-302.
8. Carboni E, Imperato A, Perezzani L, Di-Chiara G. 1989. Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats. Neuroscience 28:653-661.
9. 2A adenosine receptors. Neuroscience 97:195-204.
10. Collins SL, Kunko PM, Ladenheim B, Cadet JL, Carroll FI, Izenwasser S. 2002. Chronic cocaine increases kappa-opioid receptor density: lack of effect by selective dopamine uptake inhibitors. Synapse 45:153-158.
11. Gerrits MA, Patkina N, Zvartau EE, van-Ree JM. 1995. Opioid blockade attenuates acquisition and expression of cocaine-induced place preference conditioning in rats. Psychopharmacology 119:92-98.
12. 3H)dopamine in rat brain tissue slices. Biochem Pharmacol 24:847-852.
13. Houdi AA, Bardo MT, Van-Loon GR. 1989. Opioid mediation of cocaine-induced hyperactivity and reinforcement. Brain Res 497:195-198.
14. Kurd YL, Brown EE, Finlay JM, Fibiger HC, Gerfen CR. 1992. Cocaine self-administration differentially alters mRNA expression of striatal peptides. Brain Res Mol Brain Res 13:165-170.
15. Hurd YL, Herkenham M. 1993. Molecular alterations in the neostriatum of human cocaine addicts. Synapse 13:357-369.
16. 2 receptors in rat brain. J Pharmacol Exp Ther 251:888-893.
17. Kitchen I, Slowe S, Matthes H, Kieffer B. 1997. Quantitative autoradiographic mapping of μ, δ and κ opioid receptors in knockout mice lacking the μ-opioid receptor gene. Brain Res 778:73-88.
18. Kiyatkin EA, Brown PL. 2003. Naloxone depresses cocaine self-administration and delays its initiation on the following day. Neuroreport 14:251-255.
19. Knapp CM, Foye MM, Cottam N, Ciraulo DA, Kornetsky C. 2001. Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav 68:797-803.
20. Kreek MJ, LaForge KS, Butelman E. 2002. Pharmacotherapy of addictions. Nat Rev Drug Discov 1:710-726.
21. Kuzmin AV, Gerrits MA, van Ree JM, Zvartau EE. 1997. Naloxone inhibits the reinforcing and motivational aspects of cocaine addiction in mice. Life Sci 60:257-264.
22. 1 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 336:204-210.
23. Maisonneuve IM, Ho A, Kreek MJ. 1995. Chronic administration of a cocaine "binge" alters basal extracellular levels in male rats: an in vivo microdialysis study. J Pharmacol Exp Ther 272:652-657.
24. Manzoni O, Pujalte D, Williams J, Bockaert J. 1998. Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. J Neurosci 18:7996-8002.
25. Paxinos G, Watson C. 1986. The rat brain in stereotaxic coordinates. San Diego, California: Academic Press.
26. Poleszak E, Malec D. 2002. Adenosine receptor ligands and cocaine in conditioned place preference (CPP) test in rats. Pol J Pharmacol 54:119-126.
27. Rosin A, Kitchen I, Georgieva J. 2003. Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study. Brain Res 978:1-13.
28. Schluger JH, Bodner G, Gunduz M, Ho A, Kreek MJ. 1998. Abnormal metyrapone tests during cocaine abstinence. In: Harris LS, editor. Problems of Drug Dependence, 1997; Proceedings of the 59th Annual Scientific Meeting of CPDD. Washington, DC National Institute of Drug Abuse Research Monographs Series, p 105.
29. Schluger JH, Borg L, Ho A, Kreek MJ. 2001. Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction. Neuropsychopharmacology 24:568-575.
30. Sharpe LG, Pilotte NS, Shippenberg TS, Goodman CB, London ED. 2000. Autoradiographic evidence that prolonged withdrawal from intermittent cocaine reduces mu-opioid receptor expression in limbic regions of the rat brain. Synapse 37:292-297.
31. Sivam SP. 1989. Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. J Pharmacol Exp Ther 250:818-824.
32. Smiley PL, Johnson M, Bush L, Gibb JW, Hanson GR. 1990. Effects of cocaine on extrapyramidal and limbic dynorphin systems. J Pharmacol Exp Ther 253:938-943.
33. Spangler R, Unterwald EM, Kreek MJ. 1993. "Binge" cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Brain Res Mol Brain Res 19:323-327.
34. 1 receptor in the rat nucleus accumbens. J Neurochem 87:1478-1484.
35. Toda S, McGinty JF, Kalivas PW. 2002. Repeated cocaine administration alters the expression of genes in corticolimbic circuitry after a 3-week withdrawal: a DNA macroarray study. J Neurochem 82:1290-1299.
36. Turchan J, Przewlocka B, Lason W, Przewlocki R. 1998. Effects of repeated psychostimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain. Neuroscience 85:1051-1059.
37. Turchan J, Przewlocka B, Toth G, Laso W, Borsodi A, Przewlocki R. 1999. The effect of repeated administration of morphine, cocaine and ethanol on μ and δ opioid receptor density in the nucleus accumbens and striatum of the rat. Neuroscience 91:971-977.
38. Unterwald EM. 2001. Regulation of opioid receptors by cocaine. Ann NY Acad Sci 937:74-92.
39. Unterwald EM, Home-King J, Kreek MJ. 1992. Chronic cocaine alters brain μ opioid receptors. Brain Res 584:314-318.
40. Unterwald EM, Rubenfeld JM, Kreek MJ. 1994. Repeated cocaine administration upregulates κ and μ, but not δ, opioid receptors. Neuroreport 5:1613-1616.
41. Unterwald EM, Anton B, To T, Lam H, Evans CJ. 1998. Quantitative immunolocalization of mu opioid receptors: regulation by naltrexone. Neuroscience 85:897-905.
42. Werme M, Thoren P, Olson L, Brene S. 2000. Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen. Eur J Neurosci 12:2967-2974.
43. Wise RA. 1996. Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19:319-340.
44. Xi ZX, Ramamoorthy S, Baker DA, Shen H, Samuvel DJ, Kalivas PW. 2002. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. J Pharmacol Exp Ther 303:608-615.
45. Xi ZX, Ramamoorthy S, Shen H, Lake R, Samuvel DJ, Kalivas PW. 2003. GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. J Neurosci 23:3498-3505.
46. Yeadon M, Kitchen I. 1988. Comparative binding of μ and δ selective ligands in whole brain and pons/medulla homogenates from rat: affinity profiles of fentanyl derivatives. Neuropharmacology 27:345-348.
47. Zubieta JK, Gorelick DA, Stauffer R, Ravert HT, Dannals RF, Frost JJ. 1996. Increased μ opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine craving. Nat Med 2:1225-1229.