Lack of μ-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking exon 1 or exons 2 and 3 of the MOR-1 gene

Journal of Pharmacological Sciences

Volumn 93, Issue 4, 2003, Pages 423-429

  Mizoguchi, Hirokazu ^a   Wu, Hsiang En ^a   Narita, Minoru ^b   Sora, Ichiro ^c   Hall, F Scott ^d   Uhl, George R ^d   Loh, Horace H ^e   Nagase, Hiroshi ^f   Tseng, Leon F ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b HOSHI UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^e UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^f TORAY INDUSTRIES INC   (Japan)

Author keywords

Opioid receptor; Exon; G protein activation; Knockout mice; Spinal cord

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; DELTA OPIATE RECEPTOR AGONIST; ENDOMORPHIN 1; ENDOMORPHIN 2; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); KAPPA OPIATE RECEPTOR AGONIST; MORPHINE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; EXON; GENE SEQUENCE; GENETIC CODE; MOUSE; NOCICEPTION; NONHUMAN; SPINAL CORD; WILD TYPE;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANIMALS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; EXONS; FENTANYL; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MICE; MICE, KNOCKOUT; MORPHINE DERIVATIVES; OLIGOPEPTIDES; OPIOID PEPTIDES; RADIOLIGAND ASSAY; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; SPINAL CORD;

EID: 1042292682     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.93.423     Document Type: Article

References (22)

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