Effects of high-dose methadone maintenance on cocaine place conditioning, cocaine self-administration, and mu-opioid receptor mRNA expression in the rat brain

Neuropsychopharmacology

Volumn 31, Issue 7, 2006, Pages 1462-1474

  Leri, Francesco ^a   Zhou, Yan ^b   Goddard, Benjamin ^a   Cummins, Erin ^a   Kreek, Mary Jeanne ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cocaine; Hypothalamic pituitary adrenal axis; Methadone; mRNA; Mu opioid receptor; Proopiomelanocortin peptide

Indexed keywords

COCAINE; MESSENGER RNA; METHADONE; MU OPIATE RECEPTOR; PROOPIOMELANOCORTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; COCAINE DEPENDENCE; CONDITIONING; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG SELF ADMINISTRATION; FRONTAL CORTEX; MALE; METHADONE TREATMENT; NONHUMAN; NUCLEUS ACCUMBENS; OSMOTIC PUMP; PLACE PREFERENCE; PRIORITY JOURNAL; QUANTITATIVE STUDY; RAT; REINFORCEMENT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; COCAINE; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENE EXPRESSION; MALE; METHADONE; NARCOTICS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; RNA, MESSENGER; SELF ADMINISTRATION;

EID: 33745204845     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300927     Document Type: Article

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