Chronic cocaine-induced cardiac oxidative stress and mitogen-activated protein kinase activation: The role of Nox2 oxidase

Journal of Pharmacology and Experimental Therapeutics

Volumn 328, Issue 1, 2009, Pages 99-106

  Fan, Lampson ^a   Sawbridge, David ^a   George, Vinoj ^a   Teng, Lei ^a   Bailey, Alexis ^a   Kitchen, Ian ^a   Li, Jian Mei ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; BISINDOLYLMALEIMIDE; COCAINE; DIPHENYLIODONIUM SALT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE METHYL ESTER; OXIPURINOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ROTENONE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TIRON; TROPONIN I; CYBB PROTEIN, RAT; MEMBRANE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CELL DEATH; CHEMOLUMINESCENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; HEART CELL CULTURE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL LINE; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEART; HEART MUSCLE; HEART MUSCLE CELL; MALE; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; CELL LINE; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HEART; IN SITU NICK-END LABELING; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; MYOCYTES, CARDIAC; NADPH OXIDASE; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TRANSFECTION;

EID: 59149107397     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.145201     Document Type: Article

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