Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xL

Current Neurovascular Research

Volumn 9, Issue 1, 2012, Pages 20-31

  Wang, Shaohui ^a,b   Chong, Zhao Zhong ^a,b   Shang, Yan Chen ^a,b   Maiese, Kenneth ^a,b  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b New Jersey Medical School University Hospital Cancer Center   (United States)

Author keywords

Akt1; Apoptosis; Bax; Bim; Brain; Cytochrome c; GSK 3 ; Mitochondria; Nervous system; Oxidative stress; PI 3 K; WISP; Wnt1

Indexed keywords

BIM PROTEIN; CASPASE 3; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B; UNCLASSIFIED DRUG; WNT1 INDUCIBLE SIGNALING PATHWAY PROTEIN 1; WNT1 PROTEIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA DEGRADATION; ENZYME ACTIVATION; HIPPOCAMPUS; MEMBRANE DEPOLARIZATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NERVE CELL; NERVE DEGENERATION; NERVE INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

EID: 84863230670     PISSN: 15672026     EISSN: 18755739     Source Type: Journal    
DOI: 10.2174/156720212799297137     Document Type: Article

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