Wnt-1 dependent activation of the survival factor NF-κB in PC12 cells

Journal of Neuroscience Research

Volumn 61, Issue 1, 2000, Pages 21-32

  Bournat, J C ^a   Brown, A M C ^b,c   Soler, Alejandro Peralta ^a  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Apoptosis; GSK 3 ; NF B; PC12 cells; Wnt 1

Indexed keywords

CASEIN KINASE I; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ADHESION; CELL DEATH; CELL DIFFERENTIATION; CELL SURVIVAL; COMPETITIVE INHIBITION; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC REGULATION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSCRIPTION REGULATION;

EID: 0034235776     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20000701)61:1<21::AID-JNR3>3.0.CO;2-7     Document Type: Article

References (67)

1. Andersen DJ. 1993. Molecular control of cell fate in the neural crest. Annu Rev Neurosci 16:129-158.
2. Baeuerle P, Baltimore D. 1988a. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53:211-217.
3. Baeuerle P, Baltimore D. 1988b. IκB: a specific inhibitor of the NF-κB transcription factor. Science 242:540-546.
4. Baeuerle P, Baltimore D. 1996. NF-κB: Ten years after. Cell 87:13-20.
5. Baldwin AS. 1996. The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol 14:649-681.
6. 2+ accumulation. Proc Natl Acad Sci USA 92:9328-9332.
7. Batistatou A, Greene LA. 1991. Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol 115:461-471.
8. Beals CR, Sheridan CM, Turck CW, Gardner P, Crabtree GR. 1997. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275:1930-1933.
9. Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. 1999. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286: 1358-1362.
10. Bradley RS, Cowin P, Brown AMC. 1993. Expression of Wnt-1 in PCI2 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J Cell Biol 123:1857-1865.
11. Cadigan KM, Nusse R. 1997. Wnt signaling: a common theme in animal development. Genes Dev 11:3286-3305.
12. Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC. 1996. Wingless inactivates glycogen synthase kinase-3 via an intracellular pathway that involves a protein kinase C. EMBO J 15:4526-4536.
13. Dale TC. 1998. Signal transduction by the Wnt family of ligands. Biochem J 329:209-223.
14. Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: a play in three Akts. Genes Dev 13:2905-2927.
15. deGroot RP, Auwerx J, Bourouis M, Sassone-Corsi P. 1992. Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy. Oncogene 7:841-847.
16. Diaz-Meco MT, Municio MM, Frutos S, Sanchez P, Lozano J, Sanz L, Moscat J. 1996. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isotorms of protein kinase C. Cell 86:777-786.
17. Diehl JA, Cheng M. Roussel MF, Sherr CJ. 1998. Glycogen synthase kinase-3 ßregulates cyclin D1 proteolysis and subcellular localization. Genes Dev 12:3499-3511.
18. D'Mello SR, Anelli R, Calissano P, 1994. Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons. Exp Cell Res 211:332-338.
19. Dominguez I, Itoh K, Sokol SY. 1995. Role of glycogen synthase kinase 3β as a negative regulator of dorsoventral axis formation in Xenopus embryos. Proc Natl Acad Sci USA 92:8498-8502.
20. Dorsky RI, Moon RT, Raible DW. 1998. Control of neural crest cell fate by the Wnt signaling pathway. Nature 396:370-373.
21. Echelard Y, Vassileva G, McMahon AP. 1994. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development 120:2213-2224.
22. Fiol CJ, Williams JS, Chou C-H, Wang QM, Roach PJ, Andriasani OM. 1994. A secondary phosphorylation of CREB341 at Ser129 is required for this cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression. J Biol Chem 269: 32187-32193.
23. Giarre M, Semenov MV. Brown AMC. 1998. Wnt signaling stabilizes the dual-function protein β-catenin in diverse cell types. Ann NY Acad Sci 857:43-55.
24. Greene LA. 1978. Nerve growth factor prevents the death and stimulates neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J Cell Biol 78:747-755.
25. Greene LA, Tischler AS. 1976. Establishment of a noradrenergic clonal cell line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428.
26. 2+ / calmodulin-dependent protein kinase activity. Neurosci 57:9-20.
27. Hara K, Yonezawa K, Sakaue H. Ando A, Kotani K, Kitamura T, Kitamura Y, Ueda H, Stephens L, Jackson TR, Hawkins P, Dhand R, Clark AE, Holman GD, Waterfield MD, Kasuga M. 1994. 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for Ras activation in CHO cells. Proc Natl Acad Sci USA 91:7415-7419.
28. Hedgepeth CM, Conrad LJ, Zhang J, Huang H-C, Lee VMY, Klein PS. 1997. Activation ot the Wnt signaling pathway: a molecular mechanism for lithium action. Dev Biol 185:82-91.
29. Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, Schulze-Osthoff K, Droge W, Schmitz ML. 1998. Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of Iκ B-α and Iκ B-β. J Biol Chem 273:1288-1297.
30. Ikeya M, Lee SMK, Johnson JE, McMahon AP, Takada S, 1997. Wnt signaling required for expansion of neural crest and CNS progenitors. Nature 389:966-970.
31. Issack PS, Ziff EB. 1998. Altered expression of helix-loop-helix transcriptional regulators and cyclin D1 in Wnt-1-transformed PC12 cells. Cell Growth Differ 9:837-845.
32. Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H, Baeuerle PA. 1995. Selective recognition of the activated form of transcription factor NF-κB by a monoclonal antibody. Biol Chem Hoppe Seyler 376:9-16.
33. Kimura K, Hattori S, Kabuyama Y, Shizawa Y, Takayagani J, Nakamura S, Toki S, Matsuda Y, Onodera K, Fukui Y. 1994. Neurite outgrowth of PC12 cells is suppressed by worttmannin, a specific inhibitor of phosphatidylinositol 3-kinase. J Biol Chem 269:18961-18967.
34. Körner M, Tarantino N, Pleskoff O, Lee LM, Debré P. 1994. Activation of nuclear factor κB in human neuroblastoma cell lines. J Neurochem 62:1716-1726.
35. Lezoualc'h F, Sagara Y, Holsboer F, Behl C. 1998. High constitutive NF-κB activity mediates resistance to oxidative stress in neuronal cells. J Neurosci 18:3224-3232.
36. McMahon AP, Bradley A. 1990. The Wnt-1 (int-1) proto-oncogene is required tor development of a large region of the mouse brain. Cell 62:1073-1085.
37. Mizukami Y, Hirata T, Yoshida K. 1997. Nuclear translocation of PKC zeta during ischemia and its inhibition by wortmannin, an inhibitor of phosphatidylinositol 3-kinase. FEBS Lett 401:247-251.
38. Nakanishi H, Brewer KA, Exton JH. 1993. Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-triphosphate. J Biol Chem 268:13-16.
39. Natarajan K, Singh S, Burke Jr TR, Grumberger D, Aggarwal BB. 1996. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc Natl Acid Sci USA 93:9090-9095.
40. Nikolakaki E, Coffer PJ, Hemelsoet R, Woodgett JR, Defize LHK. 1993. Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells. Oncogene 8:833-840.
41. Nonaka S, Hough CJ, Chuang D-M. 1998. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci USA 95:2642-2647.
42. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. 1999. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401:82-85.
43. Pap M, Cooper GM. 1998. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J Biol Chem 273:19929-19932.
44. Parrizas M, Saltiel AR, LeRoith D. 1997. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways. J Biol Chem 272:154-161.
45. Peralta Soler A, Marano CW, Bryans M, Miller RD, Garulacan LA, Mauldin SK, Stamato TD, Mullin JM. 1999. Activation of NF-κB is necessary for the restoration of the barrier function of an epithelium undergoing TNF-α-induced apoptosis. Fur J Cell Biol 78:56-66.
46. Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, Collins T, Gerritsen ME. 1997. Novel inhibitors of cytokine-induced IκBα phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272:21096-21103.
47. Romashkova JA, Makarov SS. 1999. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401:86-90.
48. Rukenstein A, Rydel RE, Greene LA. 1991. Multiple agents rescue PC12 cells from serum-free death by translation- and transcription-independent mechanisms. J Neurosci 11:2552-2563.
49. Shackleford GM, Varmus HE. 1987. Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos. Cell 50:89-95.
50. Shackleford GM, Willert K, Wang J, Varmus HE. 1993. The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Neuron 11:865-875.
51. Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R. Ben-Ze'ev A. 1999. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 96:5522-5527.
52. Soler RM, Egea J, Mintening GM, Sanz-Rodriguez C, Iglesias M. Comella JX. 1998. Calmodulin is involved in membrane depolarization-mediated survival of motor neurons by phosphatidylnositol-3 kinase- and MAPK-independent pathways. J Neurosci 18:1230-1239.
53. Stambolic V, Ruel L, Woodgett JR. 1996. Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signaling in intact cells. Curr Biol 6:1664-1668.
54. Taglialatela G, Robinson R, Perez-Polo JR. 1997. Inhibition of nuclear factor κ B (NFκB) activity induces nerve growth factor-resistant apoptosis in PC12 cells. J Neurosci Res 47:155-162.
55. Thomas KR, Capecchi MR. 1990. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346:847-850.
56. Toker A, Meyer M, Reddy KK, Falck JR, Aneja R, Aneja S, Parra A, Burns DJ, Ballas LM, Cantley LC. 1994. Activation of protein kinase C family members by the novel polyphosphoinositide PtdIns-3,4-P2 and PtdIns-3,4,5-P3. J Biol Chem 269:32358-32367.
57. Tong L, Perez-Polo JR. 1995. Transcription factor DNA binding activity in PC12 cells undergoing apoptosis after glucose deprivation. Neurosci Lett 191:137-140.
58. Tong L, Perez-Polo JR. 1996. Effect of nerve growth factor on AP-1, NF-κB, and Oct DNA binding activity in apoptotic PC12 cells: extrinsic and intrinsic elements. J Neurosci Res 45:1-12.
59. Traenckner EBM, Pahl HL, Henkel T, Schmidt KN, Wilk S, Baeuerle PA. 1995. Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α: proteolysis and NF-κB activation in response to diverse stimuli. EMBO J 14:2876-2883.
60. Volonté C, Ciotti MT, Merlo D. 1994. LiCl promotes survival of GABAergic neurons from cerebellum and cerebral cortex: LiCl induces survival of GABAergic neurons. Neurosci Lett 172:6-10.
61. Wigler M, Pellicer A, Silverstein A, Axel R. 1978. Biochemical transfer of single-copy eukaryotic genes using total cellular DNA as donor. Cell 14:725-731.
62. Wilkinson DG, Bailes JA, McMahon AP. 1987. Expression of the protooncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell 50:79-80.
63. Wodarz A, Nusse R. 1998. Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 14:59-88.
64. Wood JN. 1995. Regulation of NF-κB activity in rat dorsal root ganglia and PC12 cells by tumor necrosis factor and nerve growth factor. Neurosci Lett 192:41-44.
65. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270: 1326-1330.
66. Yao R, Cooper GM. 1995. Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267:2003-2006.
67. Yano S, Tokumitsu H, Soderling TR. 1998. Calcium promotes cell survival through CaM-kinase activation of the protein-kinase-B pathway. Nature 398:584-587.