-
1
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
S. Wild, G. Roglic, A. Green, R. Sicree and H. King (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
Roglic, G.2
Green, A.3
Sicree, R.4
King, H.5
-
2
-
-
0024467521
-
Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle
-
L. Rossetti and M. R. Lauglin (1989) Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle. J Clin Invest 84: 892-899.
-
(1989)
J Clin Invest
, vol.84
, pp. 892-899
-
-
Rossetti, L.1
Lauglin, M.R.2
-
3
-
-
0020312546
-
Mast cell degranulation, hepatic glycogen depletion, and hyperglycemia in Compound 48/80 or pilocarpinetreated rats
-
R. V. Dimlich, S. F. Townsend and F. D. Reilly (1982) Mast cell degranulation, hepatic glycogen depletion, and hyperglycemia in Compound 48/80 or pilocarpinetreated rats. Hepatology 2: 372-378.
-
(1982)
Hepatology
, vol.2
, pp. 372-378
-
-
Dimlich, R.V.1
Townsend, S.F.2
Reilly, F.D.3
-
4
-
-
14944381279
-
Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications
-
J. Zdychova and R. Komers (2005) Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications. Physiol Res 54: 1-16.
-
(2005)
Physiol Res
, vol.54
, pp. 1-16
-
-
Zdychova, J.1
Komers, R.2
-
5
-
-
38549178550
-
Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice
-
S. Kagawa, Y. Soeda, H. Ishihara, T. Oya, M. Sasahara, S. Yaguchi, R. Oshita, T. Wada, H. Tsuneki and T. Sasaoka (2008) Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice. Endocrinology 149: 642-650.
-
(2008)
Endocrinology
, vol.149
, pp. 642-650
-
-
Kagawa, S.1
Soeda, Y.2
Ishihara, H.3
Oya, T.4
Sasahara, M.5
Yaguchi, S.6
Oshita, R.7
Wada, T.8
Tsuneki, H.9
Sasaoka, T.10
-
6
-
-
70549095123
-
Glucose metabolism and programmed cell death: An evolutionary and mechanistic perspective
-
A. King and E. Gottlieb (2009) Glucose metabolism and programmed cell death: an evolutionary and mechanistic perspective. Curr Opin Cell Biol 21: 885-893.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 885-893
-
-
King, A.1
Gottlieb, E.2
-
7
-
-
0034329593
-
Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase
-
P. B. Iynedjian, R. A. Roth, M. Fleischmann and A. Gjinovci (2000) Activation of protein kinase B/cAkt in hepatocytes is sufficient for the induction of expression of the gene encoding glucokinase. Biochem J 351: 621-627.
-
(2000)
Biochem J
, vol.351
, pp. 621-627
-
-
Iynedjian, P.B.1
Roth, R.A.2
Fleischmann, M.3
Gjinovci, A.4
-
8
-
-
0347356334
-
Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory elementbinding protein 1 (SREBP1) mRNAs in hepatocytes
-
P. G. Ribaux and P. B. Iynedjian (2003) Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory elementbinding protein 1 (SREBP1) mRNAs in hepatocytes. Biochem J 376: 697-705.
-
(2003)
Biochem J
, vol.376
, pp. 697-705
-
-
Ribaux, P.G.1
Iynedjian, P.B.2
-
9
-
-
0030827388
-
Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats
-
A. Krook, Y. Kawano, X. M. Song, S. Efendic, R. A. Roth, H. Wallberg-Henriksson and J. R. Zierath (1997) Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats. Diabetes 46: 2110-2114.
-
(1997)
Diabetes
, vol.46
, pp. 2110-2114
-
-
Krook, A.1
Kawano, Y.2
Song, X.M.3
Efendic, S.4
Roth, R.A.5
Wallberg-Henriksson, H.6
Zierath, J.R.7
-
10
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
A. Krook, R. A. Roth, X. J. Jiang, J. R. Zierath and H. Wallberg-Henriksson (1998) Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47: 1281-1286.
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
11
-
-
25444432767
-
Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction
-
S. Varma, B. K. Lal, R. F. Zheng, J. W. Breslin, S. Saito, P. J. Pappas, R. W. Hobson and W. N. Duran (2005) Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction. Am J Physiol-Heart C 289: H1744-H1751.
-
(2005)
Am J Physiol-Heart C
, vol.289
-
-
Varma, S.1
Lal, B.K.2
Zheng, R.F.3
Breslin, J.W.4
Saito, S.5
Pappas, P.J.6
Hobson, R.W.7
Duran, W.N.8
-
12
-
-
34547444891
-
Mechanistic insights into diabetes mellitus and oxidative stress
-
K. Maiese, Z. Z. Chong and Y. C. Shang (2007) Mechanistic insights into diabetes mellitus and oxidative stress. Curr Med Chem 14: 1729-1738.
-
(2007)
Curr Med Chem
, vol.14
, pp. 1729-1738
-
-
Maiese, K.1
Chong, Z.Z.2
Shang, Y.C.3
-
13
-
-
64249131013
-
Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats
-
J. Singh and P. Kakkar (2009) Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol 123: 22-26.
-
(2009)
J Ethnopharmacol
, vol.123
, pp. 22-26
-
-
Singh, J.1
Kakkar, P.2
-
14
-
-
19944374769
-
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
-
W. J. Kong, J. Wei, P. Abidi, M. H. Lin, S. Inaba, C. Li, Y. L. Wang, Z. Z. Wang, S. Y. Si, H. N. Pan, S. K. Wang, J. D. Wu, Y. Wang, Z. R. Li, J. W. Liu and J. D. Jiang (2004) Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med 10: 1344-1351.
-
(2004)
Nat Med
, vol.10
, pp. 1344-1351
-
-
Kong, W.J.1
Wei, J.2
Abidi, P.3
Lin, M.H.4
Inaba, S.5
Li, C.6
Wang, Y.L.7
Wang, Z.Z.8
Si, S.Y.9
Pan, H.N.10
Wang, S.K.11
Wu, J.D.12
Wang, Y.13
Li, Z.R.14
Liu, J.W.15
Jiang, J.D.16
-
15
-
-
33749327046
-
Effects of berberine on diabetes induced by alloxan and a highfat/ high-cholesterol diet in rats
-
L. Q. Tang, W. Wei, L. M. Chen and S. Liu (2006) Effects of berberine on diabetes induced by alloxan and a highfat/ high-cholesterol diet in rats. J Ethnopharmacol 108: 109-115.
-
(2006)
J Ethnopharmacol
, vol.108
, pp. 109-115
-
-
Tang, L.Q.1
Wei, W.2
Chen, L.M.3
Liu, S.4
-
16
-
-
42949145899
-
Efficacy of berberine in patients with type 2 diabetes mellitus
-
J. Yin, H. Xing and H. Ye (2008) Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism 57: 712-717.
-
(2008)
Metabolism
, vol.57
, pp. 712-717
-
-
Yin, J.1
Xing, H.2
Ye, H.3
-
17
-
-
47549100864
-
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine
-
Y. F. Zhang, X. Y. Li, D. J. Zou, W. Liu, J. L. Yang, N. Zhu, L. Huo, M. A. Wang, J. Hong, P. H. Wu, G. G. Ren and G. Ning (2008) Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocr Metab 93: 2559-2565.
-
(2008)
J Clin Endocr Metab
, vol.93
, pp. 2559-2565
-
-
Zhang, Y.F.1
Li, X.Y.2
Zou, D.J.3
Liu, W.4
Yang, J.L.5
Zhu, N.6
Huo, L.7
Wang, M.A.8
Hong, J.9
Wu, P.H.10
Ren, G.G.11
Ning, G.12
-
18
-
-
56749132290
-
Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase
-
H. A. Jung, N. Y. Yoon, H. J. Bae, B. S. Min and J. S. Choi (2008) Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase. Arch Pharm Res 31: 1405-1412.
-
(2008)
Arch Pharm Res
, vol.31
, pp. 1405-1412
-
-
Jung, H.A.1
Yoon, N.Y.2
Bae, H.J.3
Min, B.S.4
Choi, J.S.5
-
19
-
-
44949179681
-
Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose
-
W. H. Liu, P. Q. Liu, S. Tao, Y. H. Deng, X. J. Li, T. Lan, X. Y. Zhang, F. F. Guo, W. G. Huang, F. Y. Chen, H. Q. Huang and S. F. Zhou (2008) Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose. Arch Biochem Biophys 475: 128-134.
-
(2008)
Arch Biochem Biophys
, vol.475
, pp. 128-134
-
-
Liu, W.H.1
Liu, P.Q.2
Tao, S.3
Deng, Y.H.4
Li, X.J.5
Lan, T.6
Zhang, X.Y.7
Guo, F.F.8
Huang, W.G.9
Chen, F.Y.10
Huang, H.Q.11
Zhou, S.F.12
-
20
-
-
33751172922
-
Inhibition of phosphorylation of p38 MAPK involved in the protection of nephropathy by emodin in diabetic rats
-
J. P. Wang, H. Q. Huang, P. Q. Liu, F. T. Tang, J. Qin, W. G. Huang, F. Y. Chen, F. F. Guo, W. H. Liu and B. Yang (2006) Inhibition of phosphorylation of p38 MAPK involved in the protection of nephropathy by emodin in diabetic rats. Eur J Pharmacol 553: 297-303.
-
(2006)
Eur J Pharmacol
, vol.553
, pp. 297-303
-
-
Wang, J.P.1
Huang, H.Q.2
Liu, P.Q.3
Tang, F.T.4
Qin, J.5
Huang, W.G.6
Chen, F.Y.7
Guo, F.F.8
Liu, W.H.9
Yang, B.10
-
21
-
-
38849090672
-
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance
-
A. V. Chibalin, Y. Leng, E. Vieira, A. Krook, M. Bjoernholm, Y. C. Long, O. Kotova, Z. H. Zhong, F. Sakane, T. Steiler, C. Nylen, J. J. Wang, M. Laakso, M. K. Topham, M. Gilbert, H. Wallberg-Henriksson and J. R. Zierath (2008) Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell 132: 375-386.
-
(2008)
Cell
, vol.132
, pp. 375-386
-
-
Chibalin, A.V.1
Leng, Y.2
Vieira, E.3
Krook, A.4
Bjoernholm, M.5
Long, Y.C.6
Kotova, O.7
Zhong, Z.H.8
Sakane, F.9
Steiler, T.10
Nylen, C.11
Wang, J.J.12
Laakso, M.13
Topham, M.K.14
Gilbert, M.15
Wallberg-Henriksson, H.16
Zierath, J.R.17
-
22
-
-
0036724133
-
Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition
-
G. Patane, M. Anello, S. Piro, R. Vigneri, F. Purrello and A. M. Rabuazzo (2002) Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition. Diabetes 51: 2749-2756.
-
(2002)
Diabetes
, vol.51
, pp. 2749-2756
-
-
Patane, G.1
Anello, M.2
Piro, S.3
Vigneri, R.4
Purrello, F.5
Rabuazzo, A.M.6
-
23
-
-
0034055787
-
Insulin resistance in fat cells from obese Zucker rats-evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4
-
E. Carvalho, C. Rondinone and U. Smith (2000) Insulin resistance in fat cells from obese Zucker rats-evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4. Mol Cell Biochem 206: 7-16.
-
(2000)
Mol Cell Biochem
, vol.206
, pp. 7-16
-
-
Carvalho, E.1
Rondinone, C.2
Smith, U.3
-
25
-
-
34250740323
-
Akt/ PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator
-
X. Li, B. Monks, Q. Ge and M. J. Birnbaum (2007) Akt/ PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. Nature 447: 1012-1016.
-
(2007)
Nature
, vol.447
, pp. 1012-1016
-
-
Li, X.1
Monks, B.2
Ge, Q.3
Birnbaum, M.J.4
-
26
-
-
77950894143
-
A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity
-
J. L. Buescher and C. J. Phiel (2010) A noncatalytic domain of glycogen synthase kinase-3 (GSK-3) is essential for activity. J Biol Chem 285: 7957-7963.
-
(2010)
J Biol Chem
, vol.285
, pp. 7957-7963
-
-
Buescher, J.L.1
Phiel, C.J.2
-
28
-
-
65649100104
-
Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development
-
T. Force and J. R. Woodgett (2009) Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development. J Biol Chem 284: 9643-9647.
-
(2009)
J Biol Chem
, vol.284
, pp. 9643-9647
-
-
Force, T.1
Woodgett, J.R.2
-
29
-
-
63249126579
-
Targeting Hepatic Glucokinase in Type 2 Diabetes Weighing the Benefits and Risks
-
L. Agius (2009) Targeting Hepatic Glucokinase in Type 2 Diabetes Weighing the Benefits and Risks. Diabetes 58: 18-20.
-
(2009)
Diabetes
, vol.58
, pp. 18-20
-
-
Agius, L.1
-
30
-
-
4544332211
-
Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY)
-
J. L. McKinney, H. N. Cao, J. F. Robinson, D. L. Metzger, D. C. Riddell, S. R. Sanderson, D. Pacaud, J. Ho and R. A. Hegele (2004) Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY). Clin Invest Med 27: 135-141.
-
(2004)
Clin Invest Med
, vol.27
, pp. 135-141
-
-
McKinney, J.L.1
Cao, H.N.2
Robinson, J.F.3
Metzger, D.L.4
Riddell, D.C.5
Sanderson, S.R.6
Pacaud, D.7
Ho, J.8
Hegele, R.A.9
-
31
-
-
70350741368
-
Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia
-
K. K. Osbak, K. Colclough, C. Saint-Martin, N. L. Beer, C. Bellanne-Chantelot, S. Ellard and A. L. Gloyn (2009) Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia. Hum Mutat 30: 1512-1526.
-
(2009)
Hum Mutat
, vol.30
, pp. 1512-1526
-
-
Osbak, K.K.1
Colclough, K.2
Saint-Martin, C.3
Beer, N.L.4
Bellanne-Chantelot, C.5
Ellard, S.6
Gloyn, A.L.7
-
32
-
-
0028985868
-
Clinical characteristics of subjects with a missense mutation in glucokinase
-
R. C. Page, A. T. Hattersley, J. C. Levy, B. Barrow, P. Patel, D. Lo, J. S. Wainscoat, M. A. Permutt, G. I. Bell and R. C. Turner (1995) Clinical characteristics of subjects with a missense mutation in glucokinase. Diabet Med 12: 209-217.
-
(1995)
Diabet Med
, vol.12
, pp. 209-217
-
-
Page, R.C.1
Hattersley, A.T.2
Levy, J.C.3
Barrow, B.4
Patel, P.5
Lo, D.6
Wainscoat, J.S.7
Permutt, M.A.8
Bell, G.I.9
Turner, R.C.10
-
33
-
-
0032556969
-
Familial hyperinsulinism caused by an activating glucokinase mutation
-
B. Glaser, P. Kesavan, M. Heyman, E. Davis, A. Cuesta, A. Buchs, C. A. Stanley, P. S. Thornton, M. A. Permutt, F. M. Matschinsky and K. C. Herold (1998) Familial hyperinsulinism caused by an activating glucokinase mutation. N Engl J Med 338: 226-230.
-
(1998)
N Engl J Med
, vol.338
, pp. 226-230
-
-
Glaser, B.1
Kesavan, P.2
Heyman, M.3
Davis, E.4
Cuesta, A.5
Buchs, A.6
Stanley, C.A.7
Thornton, P.S.8
Permutt, M.A.9
Matschinsky, F.M.10
Herold, K.C.11
-
34
-
-
70350148368
-
Effects of Alloxan-Induced Diabetes on the Expression of Insulin Signal Transmission Molecules
-
G. Yili, P. Hong and S. Xiqun (2009) Effects of Alloxan-Induced Diabetes on the Expression of Insulin Signal Transmission Molecules. Wuhan Univ J Nat Sci 14: 447-451.
-
(2009)
Wuhan Univ J Nat Sci
, vol.14
, pp. 447-451
-
-
Yili, G.1
Hong, P.2
Xiqun, S.3
-
35
-
-
77954214500
-
Berberine inhibits PTP1B activity and mimics insulin action
-
C.H. Chen, Y.B. Zhang, C. Huang (2010) Berberine inhibits PTP1B activity and mimics insulin action. Biochem Bioph Res Co 397: 543-547.
-
(2010)
Biochem Bioph Res Co
, vol.397
, pp. 543-547
-
-
Chen, C.H.1
Zhang, Y.B.2
Huang, C.3
|