Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways

Oxidative Medicine and Cellular Longevity

Volumn 3, Issue 2, 2010, Pages 153-165

  Chong, Zhao Zhong ^a   Shang, Yan Chen ^a   Hou, Jinling ^a   Maiese, Kenneth ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; Apoptosis; Dickkopf; Oxidative stress; Phosphatidylserine; Protein kinase B; Stroke; Wingless

Indexed keywords

AKT; APOPTOSIS; APOPTOTIC; APOPTOTIC PATHWAYS; CELLULAR PROTECTION; CELLULAR TARGETS; CEREBRAL ISCHEMIA; CYTOCHROME C; ENDOGENOUS EXPRESSION; EXPERIMENTAL MODELS; GENOMIC DNA; IN-VITRO; MITOCHONDRIAL MEMBRANES; NERVOUS SYSTEM; NEURODEGENERATIVE DISEASE; NEUROPROTECTION; OVER-EXPRESSION; OXIDANT STRESS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHATIDYLSERINE; PROTEIN KINASE B; RECOMBINANT PROTEIN;

CELL DEATH; CELL MEMBRANES; GENES; PROTEINS; SIGNALING;

OXIDATIVE STRESS;

CYTOCHROME C; DICKKOPF 1 PROTEIN; GENOMIC DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLSERINE; PROTEIN ANTIBODY; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; WNT1 ANTIBODY; WNT1 PROTEIN;

AKT1 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DAMAGE; DNA DEGRADATION; ENZYME RELEASE; GENE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CELLS, CULTURED; DNA FRAGMENTATION; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; WNT1 PROTEIN;

EID: 77953706370     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.4161/oxim.3.2.11758     Document Type: Article

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