Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury

Journal of Vascular Research

Volumn 39, Issue 2, 2002, Pages 131-147

  Chong, Zhao Zhong ^a   Lin, Shi Hua ^a   Maiese, Kenneth ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Cerebrovascular endothelial cells; Cytochrome c; DNA fragmentation; Mitogen activated protein kinase; Nitric oxide; Phosphatidylserine

Indexed keywords

CASPASE 3; CASPASE 8; CYSTEINE PROTEINASE; CYTOCHROME C; DNA FRAGMENT; FREE RADICAL; GENOMIC DNA; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PHOSPHATIDYLSERINE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; STRESS ACTIVATED PROTEIN KINASE; TRYPAN BLUE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA DEGRADATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; BRAIN; CASPASE 1; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL SURVIVAL; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYTOCHROME C GROUP; DNA FRAGMENTATION; ENDOTHELIUM, VASCULAR; FREE RADICALS; IN SITU NICK-END LABELING; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NIACINAMIDE; NITRIC OXIDE; PHOSPHATIDYLSERINES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036254579     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057762     Document Type: Article

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