-
1
-
-
0022930702
-
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
-
Sen R., Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism. Cell 1986, 47:921-928.
-
(1986)
Cell
, vol.47
, pp. 921-928
-
-
Sen, R.1
Baltimore, D.2
-
2
-
-
0035883151
-
NF-kappaB signaling pathways in mammalian and insect innate immunity
-
Silverman N., Maniatis T. NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev 2001, 15:2321-2342.
-
(2001)
Genes Dev
, vol.15
, pp. 2321-2342
-
-
Silverman, N.1
Maniatis, T.2
-
3
-
-
4444376712
-
Signaling to NF-kappaB
-
Hayden M.S., Ghosh S. Signaling to NF-kappaB. Genes Dev 2004, 18:2195-2224.
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
4
-
-
77953496625
-
The NF-kappaB family of transcription factors and its regulation
-
Oeckinghaus A., Ghosh S. The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 2009, 1:a000034.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
Oeckinghaus, A.1
Ghosh, S.2
-
5
-
-
33750466230
-
Introduction to NF-kappaB: players, pathways, perspectives
-
Gilmore T.D. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 2006, 25:6680-6684.
-
(2006)
Oncogene
, vol.25
, pp. 6680-6684
-
-
Gilmore, T.D.1
-
6
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
Vallabhapurapu S., Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 2009, 27:693-733.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
7
-
-
77957570183
-
Inhibiting NF-kappaB activation by small molecules as a therapeutic strategy
-
Gupta S.C., Sundaram C., Reuter S., Aggarwal B.B. Inhibiting NF-kappaB activation by small molecules as a therapeutic strategy. Biochim Biophys Acta 2010, 1799:775-787.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 775-787
-
-
Gupta, S.C.1
Sundaram, C.2
Reuter, S.3
Aggarwal, B.B.4
-
8
-
-
0034084163
-
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
-
Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 2000, 18:621-663.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
9
-
-
0030756303
-
A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription
-
Li Z., Nabel G.J. A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription. Mol Cell Biol 1997, 17:6184-6190.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6184-6190
-
-
Li, Z.1
Nabel, G.J.2
-
10
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
-
Hoffmann A., Levchenko A., Scott M.L., Baltimore D. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 2002, 298:1241-1245.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
11
-
-
77956137185
-
IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response
-
Rao P., Hayden M.S., Long M., et al. IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response. Nature 2010, 466:1115-1119.
-
(2010)
Nature
, vol.466
, pp. 1115-1119
-
-
Rao, P.1
Hayden, M.S.2
Long, M.3
-
12
-
-
33846323310
-
A fourth IkappaB protein within the NF-kappaB signaling module
-
Basak S., Kim H., Kearns J.D., et al. A fourth IkappaB protein within the NF-kappaB signaling module. Cell 2007, 128:369-381.
-
(2007)
Cell
, vol.128
, pp. 369-381
-
-
Basak, S.1
Kim, H.2
Kearns, J.D.3
-
13
-
-
0026598520
-
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding
-
Hatada E.N., Nieters A., Wulczyn F.G., et al. The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding. Proc Natl Acad Sci U S A 1992, 89:2489-2493.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 2489-2493
-
-
Hatada, E.N.1
Nieters, A.2
Wulczyn, F.G.3
-
14
-
-
0027222103
-
The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites
-
Franzoso G., Bours V., Azarenko V., et al. The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites. EMBO J 1993, 12:3893-3901.
-
(1993)
EMBO J
, vol.12
, pp. 3893-3901
-
-
Franzoso, G.1
Bours, V.2
Azarenko, V.3
-
15
-
-
0027446955
-
The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers
-
Bours V., Franzoso G., Azarenko V., et al. The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers. Cell 1993, 72:729-739.
-
(1993)
Cell
, vol.72
, pp. 729-739
-
-
Bours, V.1
Franzoso, G.2
Azarenko, V.3
-
16
-
-
0029665444
-
Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo
-
Caamano J.H., Perez P., Lira S.A., Bravo R. Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo. Mol Cell Biol 1996, 16:1342-1348.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1342-1348
-
-
Caamano, J.H.1
Perez, P.2
Lira, S.A.3
Bravo, R.4
-
17
-
-
0035918188
-
Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs
-
Haruta H., Kato A., Todokoro K. Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs. J Biol Chem 2001, 276:12485-12488.
-
(2001)
J Biol Chem
, vol.276
, pp. 12485-12488
-
-
Haruta, H.1
Kato, A.2
Todokoro, K.3
-
18
-
-
77951877914
-
IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors
-
Okamoto K., Iwai Y., Oh-Hora M., et al. IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors. Nature 2010, 464:1381-1385.
-
(2010)
Nature
, vol.464
, pp. 1381-1385
-
-
Okamoto, K.1
Iwai, Y.2
Oh-Hora, M.3
-
19
-
-
0345826149
-
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
-
Epub 2003 Dec 2024
-
Zhou H., Wertz I., O'Rourke K., et al. Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature 2004, 427:167-171. Epub 2003 Dec 2024.
-
(2004)
Nature
, vol.427
, pp. 167-171
-
-
Zhou, H.1
Wertz, I.2
O'Rourke, K.3
-
20
-
-
0037208074
-
Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor
-
Weil R., Schwamborn K., Alcover A., Bessia C., Di Bartolo V., Israel A. Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor. Immunity 2003, 18:13-26.
-
(2003)
Immunity
, vol.18
, pp. 13-26
-
-
Weil, R.1
Schwamborn, K.2
Alcover, A.3
Bessia, C.4
Di Bartolo, V.5
Israel, A.6
-
21
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu S., Matsuzawa A., Zhang W., et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol 2008, 9:1364-1370.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
-
23
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben U., Cao Y., Xiao G., et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 2001, 293:1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
-
24
-
-
2942731516
-
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
Liao G., Zhang M., Harhaj E.W., Sun S.C. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem 2004, 279:26243-26250.
-
(2004)
J Biol Chem
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
Sun, S.C.4
-
25
-
-
42149110830
-
Control of canonical NF-kappaB activation through the NIK-IKK complex pathway
-
Zarnegar B., Yamazaki S., He J.Q., Cheng G. Control of canonical NF-kappaB activation through the NIK-IKK complex pathway. Proc Natl Acad Sci U S A 2008, 105:3503-3508.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3503-3508
-
-
Zarnegar, B.1
Yamazaki, S.2
He, J.Q.3
Cheng, G.4
-
26
-
-
0035504081
-
Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer
-
Catz S.D., Johnson J.L. Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer. Oncogene 2001, 20:7342-7351.
-
(2001)
Oncogene
, vol.20
, pp. 7342-7351
-
-
Catz, S.D.1
Johnson, J.L.2
-
27
-
-
0029814063
-
Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells
-
Wu M., Lee H., Bellas R.E., et al. Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells. EMBO J 1996, 15:4682-4690.
-
(1996)
EMBO J
, vol.15
, pp. 4682-4690
-
-
Wu, M.1
Lee, H.2
Bellas, R.E.3
-
28
-
-
20144389296
-
EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX
-
Grimm T., Schneider S., Naschberger E., et al. EBV latent membrane protein-1 protects B cells from apoptosis by inhibition of BAX. Blood 2005, 105:3263-3269.
-
(2005)
Blood
, vol.105
, pp. 3263-3269
-
-
Grimm, T.1
Schneider, S.2
Naschberger, E.3
-
29
-
-
44849106875
-
Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression
-
Wang Z., Zhang B., Yang L., Ding J., Ding H.F. Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression. JBiol Chem 2008, 283:10698-10706.
-
(2008)
JBiol Chem
, vol.283
, pp. 10698-10706
-
-
Wang, Z.1
Zhang, B.2
Yang, L.3
Ding, J.4
Ding, H.F.5
-
30
-
-
0032516651
-
IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival
-
Wu M.X., Ao Z., Prasad K.V., Wu R., Schlossman S.F. IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science 1998, 281:998-1001.
-
(1998)
Science
, vol.281
, pp. 998-1001
-
-
Wu, M.X.1
Ao, Z.2
Prasad, K.V.3
Wu, R.4
Schlossman, S.F.5
-
31
-
-
33745494351
-
Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation
-
Wegener E., Oeckinghaus A., Papadopoulou N., et al. Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation. Mol Cell 2006, 23:13-23.
-
(2006)
Mol Cell
, vol.23
, pp. 13-23
-
-
Wegener, E.1
Oeckinghaus, A.2
Papadopoulou, N.3
-
32
-
-
0037490078
-
The MAGUK family protein CARD11 is essential for lymphocyte activation
-
Hara H., Wada T., Bakal C., et al. The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity 2003, 18:763-775.
-
(2003)
Immunity
, vol.18
, pp. 763-775
-
-
Hara, H.1
Wada, T.2
Bakal, C.3
-
33
-
-
33846235557
-
The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway
-
Epub 2006 Dec 2028
-
Blonska M., Pappu B.P., Matsumoto R., et al. The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway. Immunity 2007, 26:55-66. Epub 2006 Dec 2028.
-
(2007)
Immunity
, vol.26
, pp. 55-66
-
-
Blonska, M.1
Pappu, B.P.2
Matsumoto, R.3
-
34
-
-
34248157637
-
Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1
-
Medeiros R.B., Burbach B.J., Mueller K.L., et al. Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1. Science 2007, 316:754-758.
-
(2007)
Science
, vol.316
, pp. 754-758
-
-
Medeiros, R.B.1
Burbach, B.J.2
Mueller, K.L.3
-
35
-
-
0038620475
-
2+ mobilization and NFAT cell activation in primary mouse T cells
-
2+ mobilization and NFAT cell activation in primary mouse T cells. J Exp Med 2003, 197:1525-1535.
-
(2003)
J Exp Med
, vol.197
, pp. 1525-1535
-
-
Pfeifhofer, C.1
Kofler, K.2
Gruber, T.3
-
36
-
-
18844473151
-
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
-
Sun Z., Arendt C.W., Ellmeier W., et al. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 2000, 404:402-407.
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
-
37
-
-
33847345465
-
+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B
-
+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J Immunol 2007, 178:2932-2939.
-
(2007)
J Immunol
, vol.178
, pp. 2932-2939
-
-
Saibil, S.D.1
Jones, R.G.2
Deenick, E.K.3
-
38
-
-
0026332710
-
Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element
-
Verweij C.L., Geerts M., Aarden L.A. Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-κB-like response element. J Biol Chem 1991, 266:14179-14182.
-
(1991)
J Biol Chem
, vol.266
, pp. 14179-14182
-
-
Verweij, C.L.1
Geerts, M.2
Aarden, L.A.3
-
39
-
-
0027410856
-
The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65
-
Ghosh P., Tan T.H., Rice N.R., Sica A., Young H.A. The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65. Proc Natl Acad Sci U S A 1993, 90:1696-1700.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1696-1700
-
-
Ghosh, P.1
Tan, T.H.2
Rice, N.R.3
Sica, A.4
Young, H.A.5
-
40
-
-
0346195644
-
C-Rel is required for chromatin remodeling across the IL-2 gene promoter
-
Rao S., Gerondakis S., Woltring D., Shannon M.F. c-Rel is required for chromatin remodeling across the IL-2 gene promoter. J Immunol 2003, 170:3724-3731.
-
(2003)
J Immunol
, vol.170
, pp. 3724-3731
-
-
Rao, S.1
Gerondakis, S.2
Woltring, D.3
Shannon, M.F.4
-
41
-
-
33745224579
-
Regulation of naive T cell function by the NF-kappaB2 pathway
-
Ishimaru N., Kishimoto H., Hayashi Y., Sprent J. Regulation of naive T cell function by the NF-kappaB2 pathway. Nat Immunol 2006, 7:763-772.
-
(2006)
Nat Immunol
, vol.7
, pp. 763-772
-
-
Ishimaru, N.1
Kishimoto, H.2
Hayashi, Y.3
Sprent, J.4
-
42
-
-
0030925372
-
Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB
-
Boothby M.R., Mora A.L., Scherer D.C., Brockman J.A., Ballard D.W. Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB. J Exp Med 1997, 185:1897-1907.
-
(1997)
J Exp Med
, vol.185
, pp. 1897-1907
-
-
Boothby, M.R.1
Mora, A.L.2
Scherer, D.C.3
Brockman, J.A.4
Ballard, D.W.5
-
43
-
-
0842300359
-
NF-kappaB controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes
-
Stanic A.K., Bezbradica J.S., Park J.J., et al. NF-kappaB controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes. J Immunol 2004, 172:2265-2273.
-
(2004)
J Immunol
, vol.172
, pp. 2265-2273
-
-
Stanic, A.K.1
Bezbradica, J.S.2
Park, J.J.3
-
44
-
-
0141678951
-
Mature T cells depend on signaling through the IKK complex
-
Schmidt-Supprian M., Courtois G., Tian J., et al. Mature T cells depend on signaling through the IKK complex. Immunity 2003, 19:377-389.
-
(2003)
Immunity
, vol.19
, pp. 377-389
-
-
Schmidt-Supprian, M.1
Courtois, G.2
Tian, J.3
-
45
-
-
0038375851
-
Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation
-
Egawa T., Albrecht B., Favier B., et al. Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation. Curr Biol 2003, 13:1252-1258.
-
(2003)
Curr Biol
, vol.13
, pp. 1252-1258
-
-
Egawa, T.1
Albrecht, B.2
Favier, B.3
-
46
-
-
17744386318
-
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure
-
Ruland J., Duncan G.S., Elia A., et al. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell 2001, 104:33-42.
-
(2001)
Cell
, vol.104
, pp. 33-42
-
-
Ruland, J.1
Duncan, G.S.2
Elia, A.3
-
47
-
-
0345374583
-
Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase
-
Epub 2003 Oct 1523
-
Ruefli-Brasse A.A., French D.M., Dixit V.M. Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase. Science 2003, 302:1581-1584. Epub 2003 Oct 1523.
-
(2003)
Science
, vol.302
, pp. 1581-1584
-
-
Ruefli-Brasse, A.A.1
French, D.M.2
Dixit, V.M.3
-
48
-
-
33846235157
-
Bcl10/Malt1 signaling is essential for TCR-induced NF-kappaB activation in thymocytes but dispensable for positive or negative selection
-
Jost P.J., Weiss S., Ferch U., et al. Bcl10/Malt1 signaling is essential for TCR-induced NF-kappaB activation in thymocytes but dispensable for positive or negative selection. J Immunol 2007, 178:953-960.
-
(2007)
J Immunol
, vol.178
, pp. 953-960
-
-
Jost, P.J.1
Weiss, S.2
Ferch, U.3
-
49
-
-
36549075040
-
Induction of tolerance by adoptive transfer of Treg cells
-
Nagahama K., Nishimura E., Sakaguchi S. Induction of tolerance by adoptive transfer of Treg cells. Methods Mol Biol 2007, 380:431-442.
-
(2007)
Methods Mol Biol
, vol.380
, pp. 431-442
-
-
Nagahama, K.1
Nishimura, E.2
Sakaguchi, S.3
-
50
-
-
54349086262
-
Differential requirement of PKC-theta in the development and function of natural regulatory T cells
-
Epub 2008 Oct 2008
-
Gupta S., Manicassamy S., Vasu C., Kumar A., Shang W., Sun Z. Differential requirement of PKC-theta in the development and function of natural regulatory T cells. Mol Immunol 2008, 46:213-224. Epub 2008 Oct 2008.
-
(2008)
Mol Immunol
, vol.46
, pp. 213-224
-
-
Gupta, S.1
Manicassamy, S.2
Vasu, C.3
Kumar, A.4
Shang, W.5
Sun, Z.6
-
51
-
-
1842480966
-
+ regulatory and natural killer-like T cells on signals leading to NF-{kappa}B activation
-
+ regulatory and natural killer-like T cells on signals leading to NF-{kappa}B activation. Proc Natl Acad Sci U S A 2004, 16:4566-4571.
-
(2004)
Proc Natl Acad Sci U S A
, vol.16
, pp. 4566-4571
-
-
Schmidt-Supprian, M.1
Tian, J.2
Grant, E.P.3
-
53
-
-
65549114796
-
Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery
-
Barnes M.J., Krebs P., Harris N., et al. Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. PLoS Biol 2009, 7:e51.
-
(2009)
PLoS Biol
, vol.7
-
-
Barnes, M.J.1
Krebs, P.2
Harris, N.3
-
55
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng Y., Josefowicz S., Chaudhry A., Peng X.P., Forbush K., Rudensky A.Y. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010, 463:808-812.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
56
-
-
71749088574
-
Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor
-
Long M., Park S.G., Strickland I., Hayden M.S., Ghosh S. Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity 2009, 31:921-931.
-
(2009)
Immunity
, vol.31
, pp. 921-931
-
-
Long, M.1
Park, S.G.2
Strickland, I.3
Hayden, M.S.4
Ghosh, S.5
-
58
-
-
77951158406
-
Protein kinase C-theta mediates negative feedback on regulatory T cell function
-
Zanin-Zhorov A., Ding Y., Kumari S., et al. Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science 2010, 328:372-376.
-
(2010)
Science
, vol.328
, pp. 372-376
-
-
Zanin-Zhorov, A.1
Ding, Y.2
Kumari, S.3
-
59
-
-
77955230058
-
Inflammation and the balance of Treg and Th17 cells in transplant rejection and tolerance
-
Hanidziar D., Koulmanda M. Inflammation and the balance of Treg and Th17 cells in transplant rejection and tolerance. Curr Opin Organ Transplant 2010, 15:411-415.
-
(2010)
Curr Opin Organ Transplant
, vol.15
, pp. 411-415
-
-
Hanidziar, D.1
Koulmanda, M.2
-
60
-
-
0041589416
-
T cell-intrinsic requirement for NF-kappa B induction in postdifferentiation IFN-gamma production and clonal expansion in a Th1 response
-
Corn R.A., Aronica M.A., Zhang F., et al. T cell-intrinsic requirement for NF-kappa B induction in postdifferentiation IFN-gamma production and clonal expansion in a Th1 response. J Immunol 2003, 171:1816-1824.
-
(2003)
J Immunol
, vol.171
, pp. 1816-1824
-
-
Corn, R.A.1
Aronica, M.A.2
Zhang, F.3
-
61
-
-
77954903767
-
Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli
-
Balasubramani A., Shibata Y., Crawford G.E., Baldwin A.S., Hatton R.D., Weaver C.T. Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. Immunity 2010, 33:35-47.
-
(2010)
Immunity
, vol.33
, pp. 35-47
-
-
Balasubramani, A.1
Shibata, Y.2
Crawford, G.E.3
Baldwin, A.S.4
Hatton, R.D.5
Weaver, C.T.6
-
62
-
-
23444461535
-
Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation
-
Corn R.A., Hunter C., Liou H.C., Siebenlist U., Boothby M.R. Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation. J Immunol 2005, 175:2102-2110.
-
(2005)
J Immunol
, vol.175
, pp. 2102-2110
-
-
Corn, R.A.1
Hunter, C.2
Liou, H.C.3
Siebenlist, U.4
Boothby, M.R.5
-
63
-
-
17144433112
-
Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions
-
Franzoso G., Carlson L., Scharton-Kersten T., et al. Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions. Immunity 1997, 6:479-490.
-
(1997)
Immunity
, vol.6
, pp. 479-490
-
-
Franzoso, G.1
Carlson, L.2
Scharton-Kersten, T.3
-
64
-
-
26444476013
-
Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responses
-
Marsland B.J., Nembrini C., Schmitz N., et al. Innate signals compensate for the absence of PKC-{theta} during in vivo CD8(+) T cell effector and memory responses. Proc Natl Acad Sci U S A 2005, 102:14374-14379.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14374-14379
-
-
Marsland, B.J.1
Nembrini, C.2
Schmitz, N.3
-
65
-
-
67649213521
-
Role of IL-4 and Th2 responses in allograft rejection and tolerance
-
Tay S.S., Plain K.M., Bishop G.A. Role of IL-4 and Th2 responses in allograft rejection and tolerance. Curr Opin Organ Transplant 2009, 14:16-22.
-
(2009)
Curr Opin Organ Transplant
, vol.14
, pp. 16-22
-
-
Tay, S.S.1
Plain, K.M.2
Bishop, G.A.3
-
66
-
-
0035222187
-
A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation
-
Das J., Chen C.H., Yang L., Cohn L., Ray P., Ray A. A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation. Nat Immunol 2001, 2:45-50.
-
(2001)
Nat Immunol
, vol.2
, pp. 45-50
-
-
Das, J.1
Chen, C.H.2
Yang, L.3
Cohn, L.4
Ray, P.5
Ray, A.6
-
67
-
-
77952522130
-
PI(3,4,5)P3 regulates the interaction between Akt and B23 in the nucleus
-
Kwon I.S., Lee K.H., Choi J.W., Ahn J.Y. PI(3,4,5)P3 regulates the interaction between Akt and B23 in the nucleus. BMB Rep 2010, 43:127-132.
-
(2010)
BMB Rep
, vol.43
, pp. 127-132
-
-
Kwon, I.S.1
Lee, K.H.2
Choi, J.W.3
Ahn, J.Y.4
-
68
-
-
3242790172
-
Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
-
Marsland B.J., Soos T.J., Spath G., Littman D.R., Kopf M. Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J Exp Med 2004, 200:181-189.
-
(2004)
J Exp Med
, vol.200
, pp. 181-189
-
-
Marsland, B.J.1
Soos, T.J.2
Spath, G.3
Littman, D.R.4
Kopf, M.5
-
69
-
-
8444243253
-
Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C theta
-
Salek-Ardakani S., So T., Halteman B.S., Altman A., Croft M. Differential regulation of Th2 and Th1 lung inflammatory responses by protein kinase C theta. J Immunol 2004, 173:6440-6447.
-
(2004)
J Immunol
, vol.173
, pp. 6440-6447
-
-
Salek-Ardakani, S.1
So, T.2
Halteman, B.S.3
Altman, A.4
Croft, M.5
-
70
-
-
33744910592
-
CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma
-
Medoff B.D., Seed B., Jackobek R., et al. CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma. J Immunol 2006, 176:7272-7277.
-
(2006)
J Immunol
, vol.176
, pp. 7272-7277
-
-
Medoff, B.D.1
Seed, B.2
Jackobek, R.3
-
71
-
-
77956805951
-
Memory Th1/Th2 cell generation controlled by Schnurri-2
-
Nakayama T., Kimura M.Y. Memory Th1/Th2 cell generation controlled by Schnurri-2. Adv Exp Med Biol 2010, 684:1-10.
-
(2010)
Adv Exp Med Biol
, vol.684
, pp. 1-10
-
-
Nakayama, T.1
Kimura, M.Y.2
-
72
-
-
34250848216
-
I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis
-
Greve B., Weissert R., Hamdi N., et al. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. J Immunol 2007, 179:179-185.
-
(2007)
J Immunol
, vol.179
, pp. 179-185
-
-
Greve, B.1
Weissert, R.2
Hamdi, N.3
-
73
-
-
33947204489
-
TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis
-
Marsland B.J., Nembrini C., Grun K., et al. TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis. J Immunol 2007, 178:3466-3473.
-
(2007)
J Immunol
, vol.178
, pp. 3466-3473
-
-
Marsland, B.J.1
Nembrini, C.2
Grun, K.3
-
74
-
-
79952769599
-
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in gammadelta T cells
-
Powolny-Budnicka I., Riemann M., Tanzer S., Schmid R.M., Hehlgans T., Weih F. RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in gammadelta T cells. Immunity 2011, 34:364-374.
-
(2011)
Immunity
, vol.34
, pp. 364-374
-
-
Powolny-Budnicka, I.1
Riemann, M.2
Tanzer, S.3
Schmid, R.M.4
Hehlgans, T.5
Weih, F.6
-
75
-
-
77749245828
-
C-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells
-
Visekruna A., Huber M., Hellhund A., et al. c-Rel is crucial for the induction of Foxp3(+) regulatory CD4(+) T cells but not T(H)17 cells. Eur J Immunol 2010, 40:671-676.
-
(2010)
Eur J Immunol
, vol.40
, pp. 671-676
-
-
Visekruna, A.1
Huber, M.2
Hellhund, A.3
-
76
-
-
70349243737
-
The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression
-
Jana S., Jailwala P., Haribhai D., et al. The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression. Eur J Immunol 2009, 39:2571-2583.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2571-2583
-
-
Jana, S.1
Jailwala, P.2
Haribhai, D.3
-
77
-
-
79955021405
-
High TCR stimuli prevent induced regulatory T cell differentiation in a NF-{kappa}B-dependent manner
-
Molinero L.L., Miller M.L., Evaristo C., Alegre M.L. High TCR stimuli prevent induced regulatory T cell differentiation in a NF-{kappa}B-dependent manner. J Immunol 2011.
-
(2011)
J Immunol
-
-
Molinero, L.L.1
Miller, M.L.2
Evaristo, C.3
Alegre, M.L.4
-
78
-
-
34648846165
-
Cellular mechanisms underlying acute graft rejection: time for reassessment
-
Epub 2007 Aug 2027
-
Alegre M.L., Florquin S., Goldman M. Cellular mechanisms underlying acute graft rejection: time for reassessment. Curr Opin Immunol 2007, 19:563-568. Epub 2007 Aug 2027.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 563-568
-
-
Alegre, M.L.1
Florquin, S.2
Goldman, M.3
-
80
-
-
34547917955
-
Inactivation of T-cell receptor-mediated integrin activation prolongs allograft survival in ADAP-deficient mice
-
Tian J., Pabst O., Romermann D., et al. Inactivation of T-cell receptor-mediated integrin activation prolongs allograft survival in ADAP-deficient mice. Transplantation 2007, 84:400-406.
-
(2007)
Transplantation
, vol.84
, pp. 400-406
-
-
Tian, J.1
Pabst, O.2
Romermann, D.3
-
81
-
-
70949090307
-
ADAP deficiency combined with costimulation blockade synergistically protects intestinal allografts
-
Tian J., Rodriguez-Barbosa J.I., Pabst O., et al. ADAP deficiency combined with costimulation blockade synergistically protects intestinal allografts. Transpl Int 2010, 23:71-79.
-
(2010)
Transpl Int
, vol.23
, pp. 71-79
-
-
Tian, J.1
Rodriguez-Barbosa, J.I.2
Pabst, O.3
-
82
-
-
0033023431
-
C-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function
-
Liou H.C., Jin Z., Tumang J., Andjelic S., Smith K.A., Liou M.L. c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. Int Immunol 1999, 11:361-371.
-
(1999)
Int Immunol
, vol.11
, pp. 361-371
-
-
Liou, H.C.1
Jin, Z.2
Tumang, J.3
Andjelic, S.4
Smith, K.A.5
Liou, M.L.6
-
83
-
-
0036284362
-
Qualitative differences between naive and memory T cells
-
Berard M., Tough D.F. Qualitative differences between naive and memory T cells. Immunology 2002, 106:127-138.
-
(2002)
Immunology
, vol.106
, pp. 127-138
-
-
Berard, M.1
Tough, D.F.2
-
84
-
-
77951232521
-
Recent progress and new perspectives in studying T cell responses to allografts
-
Valujskikh A., Baldwin W.M., Fairchild R.L. Recent progress and new perspectives in studying T cell responses to allografts. Am J Transplant 2010, 10:1117-1125.
-
(2010)
Am J Transplant
, vol.10
, pp. 1117-1125
-
-
Valujskikh, A.1
Baldwin, W.M.2
Fairchild, R.L.3
-
85
-
-
54049097968
-
+CD44hi T cells bypasses Bcl10: an implication of differential NF-kappaB dependence of naive and memory T cells during T cell receptor-mediated responses
-
+CD44hi T cells bypasses Bcl10: an implication of differential NF-kappaB dependence of naive and memory T cells during T cell receptor-mediated responses. J Biol Chem 2008, 283:24392-24399.
-
(2008)
J Biol Chem
, vol.283
, pp. 24392-24399
-
-
Zeng, H.1
Chen, Y.2
Yu, M.3
-
87
-
-
0042532322
-
Heterologous immunity provides a potent barrier to transplantation tolerance
-
Adams A.B., Williams M.A., Jones T.R., et al. Heterologous immunity provides a potent barrier to transplantation tolerance. J Clin Invest 2003, 111:1887-1895.
-
(2003)
J Clin Invest
, vol.111
, pp. 1887-1895
-
-
Adams, A.B.1
Williams, M.A.2
Jones, T.R.3
-
88
-
-
4444293184
-
Toll-like receptors and other links between innate and acquired alloimmunity
-
Goldstein D.R. Toll-like receptors and other links between innate and acquired alloimmunity. Curr Opin Immunol 2004, 16:538-544.
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 538-544
-
-
Goldstein, D.R.1
-
89
-
-
0141678952
-
TRAF6 is a critical factor for dendritic cell maturation and development
-
Kobayashi T., Walsh P.T., Walsh M.C., et al. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity 2003, 19:353-363.
-
(2003)
Immunity
, vol.19
, pp. 353-363
-
-
Kobayashi, T.1
Walsh, P.T.2
Walsh, M.C.3
-
90
-
-
0036199656
-
Dendritic cell development and survival require distinct NF-kappaB subunits
-
Ouaaz F., Arron J., Zheng Y., Choi Y., Beg A.A. Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity 2002, 16:257-270.
-
(2002)
Immunity
, vol.16
, pp. 257-270
-
-
Ouaaz, F.1
Arron, J.2
Zheng, Y.3
Choi, Y.4
Beg, A.A.5
-
91
-
-
33749240553
-
Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant
-
Andreakos E., Williams R.O., Wales J., Foxwell B.M., Feldmann M. Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant. Proc Natl Acad Sci U S A 2006, 103:14459-14464.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14459-14464
-
-
Andreakos, E.1
Williams, R.O.2
Wales, J.3
Foxwell, B.M.4
Feldmann, M.5
-
93
-
-
0035870086
-
Differential NF-kappaB and IkappaB gene expression during development of cardiac allograft rejection versus CD154 monoclonal antibody-induced tolerance
-
Csizmadia V., Gao W., Hancock S.A., et al. Differential NF-kappaB and IkappaB gene expression during development of cardiac allograft rejection versus CD154 monoclonal antibody-induced tolerance. Transplantation 2001, 71:835-840.
-
(2001)
Transplantation
, vol.71
, pp. 835-840
-
-
Csizmadia, V.1
Gao, W.2
Hancock, S.A.3
-
94
-
-
41149097203
-
Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation
-
Ma L., Xiang Z., Sherrill T.P., et al. Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation. Transplantation 2008, 85:903-910.
-
(2008)
Transplantation
, vol.85
, pp. 903-910
-
-
Ma, L.1
Xiang, Z.2
Sherrill, T.P.3
-
95
-
-
33748490733
-
TLR engagement prevents transplantation tolerance
-
Chen L., Wang T., Zhou P., et al. TLR engagement prevents transplantation tolerance. Am J Transplant 2006, 6:2282-2291.
-
(2006)
Am J Transplant
, vol.6
, pp. 2282-2291
-
-
Chen, L.1
Wang, T.2
Zhou, P.3
-
97
-
-
0038587747
-
The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
-
Chen L.W., Egan L., Li Z.W., Greten F.R., Kagnoff M.F., Karin M. The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med 2003, 9:575-581.
-
(2003)
Nat Med
, vol.9
, pp. 575-581
-
-
Chen, L.W.1
Egan, L.2
Li, Z.W.3
Greten, F.R.4
Kagnoff, M.F.5
Karin, M.6
-
98
-
-
2942547578
-
Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury
-
Onai Y., Suzuki J., Kakuta T., et al. Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. Cardiovasc Res 2004, 63:51-59.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 51-59
-
-
Onai, Y.1
Suzuki, J.2
Kakuta, T.3
-
99
-
-
1342280338
-
In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats
-
Cao C.C., Ding X.Q., Ou Z.L., et al. In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats. Kidney Int 2004, 65:834-845.
-
(2004)
Kidney Int
, vol.65
, pp. 834-845
-
-
Cao, C.C.1
Ding, X.Q.2
Ou, Z.L.3
-
100
-
-
0038779477
-
Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1
-
Tsuchihashi S., Tamaki T., Tanaka M., et al. Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: the role of heme oxygenase-1. Surgery 2003, 133:556-567.
-
(2003)
Surgery
, vol.133
, pp. 556-567
-
-
Tsuchihashi, S.1
Tamaki, T.2
Tanaka, M.3
-
101
-
-
20144388823
-
Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury
-
Luedde T., Assmus U., Wustefeld T., et al. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. J Clin Invest 2005, 115:849-859.
-
(2005)
J Clin Invest
, vol.115
, pp. 849-859
-
-
Luedde, T.1
Assmus, U.2
Wustefeld, T.3
-
102
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
Tsung A., Sahai R., Tanaka H., et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 2005, 201:1135-1143.
-
(2005)
J Exp Med
, vol.201
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
-
103
-
-
77951257601
-
Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury
-
Rusai K., Sollinger D., Baumann M., et al. Toll-like receptors 2 and 4 in renal ischemia/reperfusion injury. Pediatr Nephrol 2010, 25:853-860.
-
(2010)
Pediatr Nephrol
, vol.25
, pp. 853-860
-
-
Rusai, K.1
Sollinger, D.2
Baumann, M.3
-
104
-
-
67650091216
-
Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema
-
Zanotti G., Casiraghi M., Abano J.B., et al. Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. Am J Physiol Lung Cell Mol Physiol 2009, 297:L52-L63.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
-
-
Zanotti, G.1
Casiraghi, M.2
Abano, J.B.3
-
105
-
-
21744437585
-
Inhibition of nuclear factor kappaB by IkappaB superrepressor gene transfer ameliorates ischemia-reperfusion injury after experimental lung transplantation
-
Ishiyama T., Dharmarajan S., Hayama M., Moriya H., Grapperhaus K., Patterson G.A. Inhibition of nuclear factor kappaB by IkappaB superrepressor gene transfer ameliorates ischemia-reperfusion injury after experimental lung transplantation. J Thorac Cardiovasc Surg 2005, 130:194-201.
-
(2005)
J Thorac Cardiovasc Surg
, vol.130
, pp. 194-201
-
-
Ishiyama, T.1
Dharmarajan, S.2
Hayama, M.3
Moriya, H.4
Grapperhaus, K.5
Patterson, G.A.6
-
106
-
-
77955716367
-
Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
-
Ben Mkaddem S., Pedruzzi E., Werts C., et al. Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury. Cell Death Differ 2010, 17:1474-1485.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1474-1485
-
-
Ben Mkaddem, S.1
Pedruzzi, E.2
Werts, C.3
-
107
-
-
0034663755
-
Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction
-
Smiley S.T., Csizmadia V., Gao W., Turka L.A., Hancock W.W. Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction. Transplantation 2000, 70:415-419.
-
(2000)
Transplantation
, vol.70
, pp. 415-419
-
-
Smiley, S.T.1
Csizmadia, V.2
Gao, W.3
Turka, L.A.4
Hancock, W.W.5
-
108
-
-
0036853624
-
Molecular profiling of the role of the NF-kappaB family of transcription factors during alloimmunity
-
Finn P.W., He H., Ma C., et al. Molecular profiling of the role of the NF-kappaB family of transcription factors during alloimmunity. J Leukoc Biol 2002, 72:1054-1062.
-
(2002)
J Leukoc Biol
, vol.72
, pp. 1054-1062
-
-
Finn, P.W.1
He, H.2
Ma, C.3
-
109
-
-
0036677311
-
Enforced c-REL deficiency prolongs survival of islet allografts1
-
Yang H., Thomas D., Boffa D.J., et al. Enforced c-REL deficiency prolongs survival of islet allografts1. Transplantation 2002, 74:291-298.
-
(2002)
Transplantation
, vol.74
, pp. 291-298
-
-
Yang, H.1
Thomas, D.2
Boffa, D.J.3
-
110
-
-
0037296110
-
Impaired NF-kB activation in T cells permits tolerance to primary heart allografts and to secondary donor skin grafts
-
Zhou P., Hwang K.W., Palucki D.A., et al. Impaired NF-kB activation in T cells permits tolerance to primary heart allografts and to secondary donor skin grafts. Am J Transplant 2003, 3:139-147.
-
(2003)
Am J Transplant
, vol.3
, pp. 139-147
-
-
Zhou, P.1
Hwang, K.W.2
Palucki, D.A.3
-
111
-
-
14844347541
-
Transplantation tolerance in NF-kappaB-impaired mice is not due to regulation but is prevented by transgenic expression of Bcl-xL
-
Zhou P., Balin S.J., Mashayekhi M., Hwang K.W., Palucki D.A., Alegre M.L. Transplantation tolerance in NF-kappaB-impaired mice is not due to regulation but is prevented by transgenic expression of Bcl-xL. J Immunol 2005, 174:3447-3453.
-
(2005)
J Immunol
, vol.174
, pp. 3447-3453
-
-
Zhou, P.1
Balin, S.J.2
Mashayekhi, M.3
Hwang, K.W.4
Palucki, D.A.5
Alegre, M.L.6
-
112
-
-
67651154525
-
Fas mediates cardiac allograft acceptance in mice with impaired T cell-intrinsinc NF-kB signaling
-
Accepted with minor revisions
-
Molinero L.L., Wang Y., Zhou P., Yagita H., Alegre M.L. Fas mediates cardiac allograft acceptance in mice with impaired T cell-intrinsinc NF-kB signaling. Transpl Int 2009, Accepted with minor revisions.
-
(2009)
Transpl Int
-
-
Molinero, L.L.1
Wang, Y.2
Zhou, P.3
Yagita, H.4
Alegre, M.L.5
-
113
-
-
37549065563
-
Epidermal Langerhans cells play a major role in skin allograft rejection in mice with NF-kB-impaired T cells
-
Molinero L., Zhou P., Wang Y., et al. Epidermal Langerhans cells play a major role in skin allograft rejection in mice with NF-kB-impaired T cells. Am J Transplant 2008, 8:21-31.
-
(2008)
Am J Transplant
, vol.8
, pp. 21-31
-
-
Molinero, L.1
Zhou, P.2
Wang, Y.3
-
114
-
-
47949130474
-
A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection
-
Manicassamy S., Yin D., Zhang Z., Molinero L.L., Alegre M.L., Sun Z. A critical role for protein kinase C-theta-mediated T cell survival in cardiac allograft rejection. J Immunol 2008, 181:513-520.
-
(2008)
J Immunol
, vol.181
, pp. 513-520
-
-
Manicassamy, S.1
Yin, D.2
Zhang, Z.3
Molinero, L.L.4
Alegre, M.L.5
Sun, Z.6
-
115
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
Chin A.I., Dempsey P.W., Bruhn K., Miller J.F., Xu Y., Cheng G. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 2002, 416:190-194.
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
Cheng, G.6
-
116
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K., Hernandez L.D., Galan J.E., Janeway C.A., Medzhitov R., Flavell R.A. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002, 110:191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway, C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
117
-
-
0347093172
-
Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation
-
Ruefli-Brasse A.A., Lee W.P., Hurst S., Dixit V.M. Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation. J Biol Chem 2004, 279:1570-1574.
-
(2004)
J Biol Chem
, vol.279
, pp. 1570-1574
-
-
Ruefli-Brasse, A.A.1
Lee, W.P.2
Hurst, S.3
Dixit, V.M.4
-
118
-
-
44249107560
-
RIP2 is required for NOD signaling but not for Th1 cell differentiation and cellular allograft rejection
-
Fairhead T., Lian D., McCully M.L., Garcia B., Zhong R., Madrenas J. RIP2 is required for NOD signaling but not for Th1 cell differentiation and cellular allograft rejection. Am J Transplant 2008, 8:1143-1150.
-
(2008)
Am J Transplant
, vol.8
, pp. 1143-1150
-
-
Fairhead, T.1
Lian, D.2
McCully, M.L.3
Garcia, B.4
Zhong, R.5
Madrenas, J.6
-
119
-
-
78649881910
-
Nuclear factor-kappaB inducing kinase is required for graft-versus-host disease
-
Sanchez-Valdepenas C., Casanova L., Colmenero I., et al. Nuclear factor-kappaB inducing kinase is required for graft-versus-host disease. Haematologica 2010, 95:2111-2118.
-
(2010)
Haematologica
, vol.95
, pp. 2111-2118
-
-
Sanchez-Valdepenas, C.1
Casanova, L.2
Colmenero, I.3
-
120
-
-
0037105629
-
Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig
-
Bonham C.A., Peng L., Liang X., et al. Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig. J Immunol 2002, 169:3382-3391.
-
(2002)
J Immunol
, vol.169
, pp. 3382-3391
-
-
Bonham, C.A.1
Peng, L.2
Liang, X.3
-
122
-
-
33646421393
-
Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines
-
Blanco B., Perez-Simon J.A., Sanchez-Abarca L.I., et al. Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines. Blood 2006, 107:3575-3583.
-
(2006)
Blood
, vol.107
, pp. 3575-3583
-
-
Blanco, B.1
Perez-Simon, J.A.2
Sanchez-Abarca, L.I.3
-
123
-
-
67650767034
-
+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population
-
+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population. Haematologica 2009, 94:975-983.
-
(2009)
Haematologica
, vol.94
, pp. 975-983
-
-
Blanco, B.1
Perez-Simon, J.A.2
Sanchez-Abarca, L.I.3
-
124
-
-
67649586605
-
Abrogation of anti-HLA antibodies via proteasome inhibition
-
Trivedi H.L., Terasaki P.I., Feroz A., et al. Abrogation of anti-HLA antibodies via proteasome inhibition. Transplantation 2009, 87:1555-1561.
-
(2009)
Transplantation
, vol.87
, pp. 1555-1561
-
-
Trivedi, H.L.1
Terasaki, P.I.2
Feroz, A.3
-
125
-
-
33645694582
-
Immunosuppression: evolution in practice and trends, 1994-2004
-
Meier-Kriesche H.U., Li S., Gruessner R.W., et al. Immunosuppression: evolution in practice and trends, 1994-2004. Am J Transplant 2006, 6:1111-1131.
-
(2006)
Am J Transplant
, vol.6
, pp. 1111-1131
-
-
Meier-Kriesche, H.U.1
Li, S.2
Gruessner, R.W.3
-
126
-
-
0032230316
-
A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids
-
Wissink S., van Heerde E.C., vand der Burg B., van der Saag P.T. A dual mechanism mediates repression of NF-kappaB activity by glucocorticoids. Mol Endocrinol 1998, 12:355-363.
-
(1998)
Mol Endocrinol
, vol.12
, pp. 355-363
-
-
Wissink, S.1
van Heerde, E.C.2
vand der Burg, B.3
van der Saag, P.T.4
-
127
-
-
0028895152
-
Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin
-
Nadler S.G., Eversole A.C., Tepper M.A., Cleaveland J.S. Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin. Ther Drug Monit 1995, 17:700-703.
-
(1995)
Ther Drug Monit
, vol.17
, pp. 700-703
-
-
Nadler, S.G.1
Eversole, A.C.2
Tepper, M.A.3
Cleaveland, J.S.4
-
128
-
-
0024837470
-
The effects of deoxyspergualin on human lymphocyte proliferation in vitro
-
Kerr P.G., Atkins R.C. The effects of deoxyspergualin on human lymphocyte proliferation in vitro. Transplant Proc 1989, 21:3765-3766.
-
(1989)
Transplant Proc
, vol.21
, pp. 3765-3766
-
-
Kerr, P.G.1
Atkins, R.C.2
-
129
-
-
0029960987
-
Deoxyspergualin: mechanism of action and pharmacokinetics
-
Ramos E.L., Nadler S.G., Grasela D.M., Kelley S.L. Deoxyspergualin: mechanism of action and pharmacokinetics. Transplant Proc 1996, 28:873-875.
-
(1996)
Transplant Proc
, vol.28
, pp. 873-875
-
-
Ramos, E.L.1
Nadler, S.G.2
Grasela, D.M.3
Kelley, S.L.4
-
130
-
-
0026667296
-
In vivo and in vitro mechanisms of cardiac allograft acceptance in the rat after short treatment with 15-deoxyspergualin
-
Jiang H., Takahara S., Kyo M., et al. In vivo and in vitro mechanisms of cardiac allograft acceptance in the rat after short treatment with 15-deoxyspergualin. Transplant Int 1992, 5:139-144.
-
(1992)
Transplant Int
, vol.5
, pp. 139-144
-
-
Jiang, H.1
Takahara, S.2
Kyo, M.3
-
131
-
-
0026729602
-
Extended functional survival of murine islet allografts with 15- deoxyspergualin
-
Kaufman D.B., Field M.J., Gruber S.A., et al. Extended functional survival of murine islet allografts with 15- deoxyspergualin. TransplantProc 1992, 24:1045-1047.
-
(1992)
TransplantProc
, vol.24
, pp. 1045-1047
-
-
Kaufman, D.B.1
Field, M.J.2
Gruber, S.A.3
-
132
-
-
0026095591
-
Effect of FK-506 on heart allograft survival in the highly sensitized recipient rats as compared with ciclosporin and 15-deoxyspergualin
-
Jiang H., Takahara S., Kyo M., Kokado Y., Ishibashi M., Sonoda T. Effect of FK-506 on heart allograft survival in the highly sensitized recipient rats as compared with ciclosporin and 15-deoxyspergualin. Eur Surg Res 1991, 23:201-205.
-
(1991)
Eur Surg Res
, vol.23
, pp. 201-205
-
-
Jiang, H.1
Takahara, S.2
Kyo, M.3
Kokado, Y.4
Ishibashi, M.5
Sonoda, T.6
-
133
-
-
0028200718
-
Partial inhibition of allograft arteriosclerosis (chronic rejection) by 15-deoxyspergualin
-
Raisanen-Sokolowski A., Yilmaz S., Tufveson G., Hayry P. Partial inhibition of allograft arteriosclerosis (chronic rejection) by 15-deoxyspergualin. Transplantation 1994, 57:1772-1777.
-
(1994)
Transplantation
, vol.57
, pp. 1772-1777
-
-
Raisanen-Sokolowski, A.1
Yilmaz, S.2
Tufveson, G.3
Hayry, P.4
-
134
-
-
0037307921
-
Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance
-
Min W.P., Zhou D., Ichim T.E., et al. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. J Immunol 2003, 170:1304-1312.
-
(2003)
J Immunol
, vol.170
, pp. 1304-1312
-
-
Min, W.P.1
Zhou, D.2
Ichim, T.E.3
-
135
-
-
29144482355
-
Accumulation of T cells with potent regulatory properties and restricted Vbeta7-TCR rearrangements in tolerated allografts
-
Heslan J.M., Beriou G., Le Luduec J.B., et al. Accumulation of T cells with potent regulatory properties and restricted Vbeta7-TCR rearrangements in tolerated allografts. Transplantation 2005, 80:1476-1484.
-
(2005)
Transplantation
, vol.80
, pp. 1476-1484
-
-
Heslan, J.M.1
Beriou, G.2
Le Luduec, J.B.3
-
136
-
-
79951992393
-
Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile
-
Le Texier L., Thebault P., Lavault A., et al. Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile. Am J Transplant 2011, 11:429-438.
-
(2011)
Am J Transplant
, vol.11
, pp. 429-438
-
-
Le Texier, L.1
Thebault, P.2
Lavault, A.3
-
137
-
-
0037469068
-
Monotherapy with LF 15-0195, an analogue of 15-deoxyspergualin, significantly prolongs renal allograft survival in monkeys
-
Yang H., Chen G., Kanai N., et al. Monotherapy with LF 15-0195, an analogue of 15-deoxyspergualin, significantly prolongs renal allograft survival in monkeys. Transplantation 2003, 75:1166-1171.
-
(2003)
Transplantation
, vol.75
, pp. 1166-1171
-
-
Yang, H.1
Chen, G.2
Kanai, N.3
-
138
-
-
67650527333
-
Long-term outcome of ABO-incompatible living-donor liver transplantation: a single-center experience
-
Kawagishi N., Takeda I., Miyagi S., et al. Long-term outcome of ABO-incompatible living-donor liver transplantation: a single-center experience. J Hepatobiliary Pancreat Surg 2009, 16:468-472.
-
(2009)
J Hepatobiliary Pancreat Surg
, vol.16
, pp. 468-472
-
-
Kawagishi, N.1
Takeda, I.2
Miyagi, S.3
|