Protein kinase C-θ mediates negative feedback on regulatory T cell function

Science

Volumn 328, Issue 5976, 2010, Pages 372-376

  Zanin Zhorov, Alexandra ^a   Ding, Yi ^a   Kumari, Sudha ^a   Attur, Mukundan ^a   Hippen, Keli L ^b   Brown, Maryanne ^c   Blazar, Bruce R ^b   Abramson, Steven B ^a   Lafaille, Juan J ^a   Dustin, Michael L ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C THETA; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

BIOCHEMISTRY; CYTOLOGY; DISEASE CONTROL; DISEASE TREATMENT; ENZYME ACTIVITY; IMMUNE SYSTEM; PROTEIN; TUMOR;

ANIMAL EXPERIMENT; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; COLITIS; CONTROLLED STUDY; CYTOKINE RELEASE; EFFECTOR CELL; ENZYME ACTIVATION; HUMAN; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RHEUMATOID ARTHRITIS;

ADOLESCENT; ADULT; AGED; ANIMALS; ARTHRITIS, RHEUMATOID; COLITIS; ENZYME INHIBITORS; FEEDBACK, PHYSIOLOGICAL; HUMANS; IMMUNOLOGICAL SYNAPSES; INFLAMMATION; INTERFERON-GAMMA; ISOENZYMES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MIDDLE AGED; PROTEIN KINASE C; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

ERAGROSTIS TEF; MUS;

EID: 77951158406     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1186068     Document Type: Article

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