The quiescent cellular state is Arf/p53-Dependent and associated with H2AX downregulation and genome stability

International Journal of Molecular Sciences

Volumn 13, Issue 5, 2012, Pages 6492-6506

  Yoshioka, Ken Ichi ^a   Atsumi, Yuko ^a,b   Fukuda, Hirokazu ^a   Masutani, Mitsuko ^a   Teraoka, Hirobumi ^c  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Arf p53; Cancer; Genome stability; H2AX; Immortality; Senescence; Tetraploidy

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; DNA; PROTEIN P53; CYCLIN DEPENDENT KINASE INHIBITOR 2A; H2AFX PROTEIN, HUMAN; HISTONE; TP53 PROTEIN, HUMAN;

CARCINOGENESIS; CELL TRANSFORMATION; CHROMOSOME TRANSLOCATION; DISEASE ASSOCIATION; DNA SEQUENCE; DOWN REGULATION; GENE MUTATION; GENE REARRANGEMENT; GENOMIC INSTABILITY; HUMAN; MICROSATELLITE INSTABILITY; MOUSE; NONHUMAN; REGULATORY MECHANISM; REVIEW; TETRAPLOIDY; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; MUTATION; NEOPLASMS; TETRAPLOIDY; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84861535987     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13056492     Document Type: Review

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