Molecular dynamics simulations of the Bcl-2 protein to predict the structure of its unordered flexible loop domain

Journal of Molecular Modeling

Volumn 18, Issue 5, 2012, Pages 1885-1906

  Raghav, Pawan Kumar ^a   Verma, Yogesh Kumar ^a   Gangenahalli, Gurudutta U ^a  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Apoptosis; Bcl 2; Essential dynamics; Flexible loop domain; Loop modeling; MD simulations

Indexed keywords

ASPARTIC ACID; BH3 PROTEIN; BINDING PROTEIN; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PRESENILIN 1; PROTEIN BCL 2; PROTEIN BH1; PROTEIN BH2; PROTEIN BH4; PROTEIN FKBP38; PROTEIN KINASE C; SERINE; STRESS ACTIVATED PROTEIN KINASE 1; THREONINE; UBIQUITIN; UNCLASSIFIED DRUG;

ACCURACY; APOPTOSIS; ARTICLE; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; QUALITY CONTROL; REGULATORY MECHANISM; SIMULATION;

AMINO ACID SEQUENCE; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; DATABASES, PROTEIN; HUMANS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84861233732     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-011-1201-6     Document Type: Article

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