Contribution of hydrogen bonds to the conformational stability of human lysozyme: Calorimetry and X-ray analysis of six Ser → Ala mutants

Biochemistry

Volumn 38, Issue 20, 1999, Pages 6623-6629

  Takano, Kazufumi ^a   Yamagata, Yuriko ^a   Kubota, Masahiro ^a   Funahashi, Jun ^a   Fujii, Satoshi ^a,b   Yutani, Katsuhide ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; LYSOZYME; MUTANT PROTEIN; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ENTHALPY; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME STABILITY; HUMAN; HYDROGEN BOND; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ALANINE; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLOGRAPHY, X-RAY; ENERGY TRANSFER; ENZYME STABILITY; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MURAMIDASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0033580613     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9901228     Document Type: Article

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