Safety and efficacy of high-protein diets for weight loss

Proceedings of the Nutrition Society

Volumn 71, Issue 2, 2012, Pages 339-349

  Johnstone, Alexandra M ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Appetite; Body composition; High protein diet; Metabolic profile; Weight loss

Indexed keywords

BIOLOGICAL MARKER;

ANTIOXIDANT ACTIVITY; APPETITE; BLOOD PRESSURE; BODY COMPOSITION; BODY WEIGHT; BONE; CARDIOVASCULAR RISK; COGNITION; CONFERENCE PAPER; DIET SUPPLEMENTATION; EXERCISE; FOLLOW UP; HUMAN; HYPERLIPIDEMIA; INTESTINE; KIDNEY FUNCTION; LOW CARBOHYDRATE DIET; MACRONUTRIENT; MENTAL FUNCTION; OSTEOPOROSIS; PROTEIN DIET; STRESS; WEIGHT CHANGE; WEIGHT REDUCTION;

APPETITE; BONE AND BONES; CARDIOVASCULAR SYSTEM; DIET, REDUCING; DIETARY PROTEINS; ENERGY INTAKE; GASTROINTESTINAL TRACT; HUMANS; KIDNEY; OBESITY; SATIETY RESPONSE; TREATMENT OUTCOME; WEIGHT LOSS;

EID: 84860859846     PISSN: 00296651     EISSN: 14752719     Source Type: Journal    
DOI: 10.1017/S0029665112000122     Document Type: Conference Paper

References (109)

1. Henderson et al. (2003) The National Diet and Nutrition Survey: Adults Aged 19 to 64 Years, vol 2: Energy, Protein, Carbohydrate, fat and Alcohol Intake. London: The Stationery Office.
2. Gardner CD, Kiazand A, Alhassan S et al. (2007) Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: the A TO Z Weight Loss Study: a randomized trial. JAMA 297, 969-977.
3. Wyld B, Harrison A & Noakes M (2010) The CSIRO Total Wellbeing Diet Book 1: sociodemographic differences and impact on weight loss and well-being in Australia. Public Health Nutr 13, 2105-2110.
4. Trumbo P, Schlicker S, Yates AA et al. (2002) Food and Nutrition Board of the Institute of Medicine, The National Academies. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. Food and Nutrition Board, Institute of Medicine, The National Academies, Washington DC, USA. J Am Diet Assoc 102, 1621-1630.
5. St Jeor ST, Howard BV, Prewitt TE et al. (2001) Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. Dietary protein and weight reduction: a statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. Circulation 104, 1869-1874.
6. Astrup A (2005) The satiating power of protein - a key to obesity prevention? Am J Clin Nutr 82, 1-2.
7. Astrup A, Meinert Larsen T & Harper A (2004) Atkins and other low-carbohydrate diets: hoax or an effective tool for weight loss? Lancet 364, 897-899.
8. Russell WR, Gratz SW, Duncan S et al. (2011) High protein, reduced carbohydrate weight loss diets promote metabolite profiles likely to be detrimental to colonic health. Am J Clin Nutr 93, 1062-1072.
9. World Cancer Research Fund (1997) Food, Nutrition, and the Prevention of Cancer: a Global Perspective. Washington, DC: WCRF/AICR.
10. Department of Health (1991) Dietary Reference Values for Food, Energy and Nutrients for the United Kingdom, pp. 78-84. London: HMSO.
11. Scheppach W, Bingham S, Boutron-Ruault MC et al. (1999) WHO consensus statement on the role of nutrition in colorectal cancer. Eur J Cancer Prev 8, 57-62.
12. Chief Medical Officer?s Committee on Medical Aspects of Food (1994) Nutritional Aspects of the Development of Cancer. No. 48. London: HMSO.
13. FAO (2006a) World agriculture: towards 2030/2050 Interim Report. Rome: FAO.
14. FAO (2006b) FAO statistical databases. Rome: FAO; available at http://faostat.fao.org/default.aspx
15. Livewell (2011) A balance of healthy and sustainable food choices. A Commissioned Report for World Wildlife Fund; available at http://assets.wwf.org. uk/downloads/ livewell-report-jan11.pdf
16. Lambert CP, Frank LL & EVans WJ (2004) Macronutrient considerations for the sport of bodybuilding. Sports Med 34, 317-327.
17. Poortmans JR & Dellalieux O (2000) Do regular high protein diets have potential health risks on kidney function in athletes? Int J Sport Nur Exerc Metab 10, 28-38.
18. Brandle E, Sieberth HG & Hautmann RE (1996) Effect of chronic dietary protein intake on the renal function in healthy subjects. Eur J Clin Nutr 50, 734-740.
19. Johnstone AM, Horgan GW, Murison SD et al. (2008) Hunger and appetite response to a high-protein ketogenic diet in obese men feeding ad libitum. Am J Clin Nutr 87, 44-55.
20. Johnstone AM, Lobley GE, Horgan GW et al. (2011) Effects of a high-protein, low-carbohydrate weight loss diet on antioxidant status, endothelial function and plasma indices of cardio-metabolic profile. Br J Nutr 106, 282-291.
21. Wycherley TP, Noakes M, Clifton PM et al. (2010) A highprotein diet with resistance exercise training improves weight loss and body composition in overweight and obese patients with type 2 diabetes. Diabetes Care 33, 969-976.
22. Krieger JW, Sitren HS, Daniels MJ et al. (2006) Effects of variation in protein and carbohydrate intake on body mass and composition during energy restriction: a metaregression 1. Am J Clin Nutr 83, 260-274.
23. Clifton PM, Noakes M, Keogh J et al. (2003) Effect of an energy reduced high protein red meat diet on weight loss and metabolic parameters in obese women. Asia Pac J Clin Nutr 12, Suppl., S10.
24. Larsen RN, Mann NJ, Maclean E et al. (2011) The effect of high-protein, low-carbohydrate diets in the treatment of type 2 diabetes: a 12 month randomised controlled trial. Diabetologia 54, 731-740.
25. Due A, Toubro S & Skov AR (2004) Effect of normal-fat diets, either medium or high in protein, on body weight in overweight subjects: a randomised 1-year trial. Int J Obes Relat Metab Disord 28, 1283-1290.
26. Clifton P (2006) The science behind weight loss diets - a brief review. Aust Fam Physician 35, 580-582.
27. Clifton P (2006) Value of high-protein diet is clearer than drawbacks. Nature 439, 266.
28. Larsen TM, Dalskov S, Van Baak M et al. (2010) The Diet, Obesity and Genes (Diogenes) Dietary Study in eight European countries - a comprehensive design for long-term intervention. Obes Rev 11, 76-91.
29. Gilbert JA, Bendsen NT, Tremblay A et al. (2011) Effect of proteins from different sources on body composition. Nutr Metab Cardiovasc Dis 21, Suppl. 2, B16-31.
30. Lejeune MP, Kovacs EM & Westerterp-Plantenga MS (2005) Additional protein intake limits weight regain after weight loss in humans. Br J Nutr 93, 281e9.
31. Claessens M, Van Baak MA, Monsheimer S et al. (2009) The effect of a low-fat, high-protein or high-carbohydrate ad libitum diet on weight loss maintenance and metabolic risk factors. Int J Obes (Lond) 33, 296-304.
32. Layman DK, EVans EM, Erickson D et al. (2009) A moderate- protein diet produces sustained weight loss and longterm changes in body composition and blood lipids in obese adults. J Nutr 139, 514-521.
33. Westerterp-Plantenga MS (2003) The significance of protein in food intake and body weight regulation. Curr Opin Clin Nutr Metab Care 6, 635-638.
34. Halton TL & Hu FB (2004) The effects of high protein diets on thermogenesis, satiety and weight loss: a critical review. J Am Coll Nutr 23, 373-385.
35. Geliebter A (1979) Effects of equicaloric loads of protein, fat, and carbohydrate on food intake in the rat and man. Physiol Behav 22, 267-273.
36. De Graaf C, Hulshof T, Weststrate JA et al. (1992) Short term effects of different amounts of protein, fats and carbohydrate on satiety. Am J Clin Nutr 55, 33-38.
37. Veldhorst MA, Nieuwenhuizen AG, Hochstenbach- Waelen A et al. (2009c) Dose-dependent satiating effect of whey relative to casein or soy. Physiol Behav 96, 675-682.
38. Veldhorst MA, Nieuwenhuizen AG, Hochstenbach-Waelen A et al. (2009a) Effects of high and normal soyprotein breakfasts on satiety and subsequent energy intake, including amino acid and ?satiety? hormone responses. Eur J Nutr 48, 92-100.
39. Veldhorst MA, Nieuwenhuizen AG, Hochstenbach-Waelen A et al. (2009b) Effects of complete whey-protein breakfasts versus whey without GMP-breakfasts on energy intake and satiety. Appetite 52, 388-395.
40. McCrory MA, Fuss PJ, Saltzman E et al. (2000) Dietary determinants of energy intake and weight regulation in healthy adults. J Nutr 130, 2S Suppl., 276S-279S.
41. Rolls BJ, Rowe EA, Rolls ET et al. (1981) Variety in a meal enhances food intake in man. Physiol Behav 26, 215-221.
42. Stubbs RJ, Johnstone AM, Mazlan N et al. (2001) Effect of altering the variety of sensorially distinct foods, of the same macronutrient content, on food intake and body weight in men. Eur J Clin Nutr 55, 19-28.
43. Nickols-Richardson SM, Coleman MD, Volpe JJ et al. (2005) Perceived hunger is lower and weight loss is greater in overweight premenopausal women consuming a lowcarbohydrate/ high-protein vs high-carbohydrate/low-fat diet. J Am Diet Assoc 105, 1433-1437.
44. Hetherington MM, Pirie LM & Nabb S (2002) Stimulus satiation: effects of repeated exposure to foods on pleasantness and intake. Appetite 38, 19-28.
45. Kerstetter JE, O?Brien KO & Insogna KL (2003) Dietary protein, calcium metabolism, and skeletal homeostasis revisited. Am J Clin Nutr 78, 3 Suppl., 584S-592S.
46. Cao JJ, Johnson LK & Hunt JR (2011) A diet high in meat protein and potential renal acid load increases fractional calcium absorption and urinary calcium excretion without affecting markers of bone resorption or formation in postmenopausal women. J Nutr 141, 391-397.
47. Marcason W (2010) What is the effect of a high-protein diet on bone health? J Am Diet Assoc 110, 812.
48. Darling AL, Millward DJ, Torgerson DJ et al. (2009) Dietary protein and bone health: a systematic review and meta-analysis. Am J Clin Nutr 90, 1674-1692.
49. Munger RG, Cerhan JR & Chiu BC (1999) Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women. Am J Clin Nutr 69, 147-152.
50. Cao JJ & Nielsen FH (2010) Acid diet (high-meat protein) effects on calcium metabolism and bone health. Curr Opin Clin Nutr Metab Care 13, 698-702.
51. Friedman AN (2004) High-protein diets: potential effects on the kidney in renal health and disease. Am J Kidney Dis 44, 950-962.
52. Lentine K & Wrone EM (2004) New insights into protein intake and progression of renal disease. Curr Opin Nephrol Hypertens 13, 333-336.
53. Frank H, Graf J, Amann-Gassner U et al. (2009/2010) Effect of short-term high-protein compared with normalprotein diets on renal hemodynamics and associated variables in healthy young men. Am J Clin Nutr 90, 1509- 1516 (Epublication 7 October 2009). Erratum in: Am J Clin Nutr 91, 494. Graf, Juliane [corrected to Graf, Julia].
54. Brenner BM, Lawler EV & Mackenzie HS (1996) The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 49, 1774-1777.
55. Eisenstein J, Roberts SB, Dallal G et al. (2002) High protein weight loss diets: are they safe and do they work? A review of the experimental and epidemiologic data. Nutr Rev 60, 189-200.
56. Kim Y & Linkswiler HM (1979) Effect of level of protein intake on calcium metabolism and on parathyroid and renal function in the adult human male. J Nutr 109, 1399-1404.
57. Schutte SA, Zemel MB & Linkswiler HM (1980) Studies on the mechanism of protein induced hypercalciuria in older men and women. J Nutr 110, 305-315.
58. Hegsted M & Linkswiler HM (1981) Long term effects of level of protein intake on calcium metabolism in young adult women. J Nutr 111, 244-251.
59. Rodriquez-Iturbe B, Herrera J & Garcia R (1988) Relationship between glomerular filtration rate and renal blood flow at different levels of protein induced hyperfiltration in man. Clin Sci 74, 11-15.
60. Skov AR, Toubro S, Bulow J et al. (1999) Changes in renal function during weight loss induced by high vs low protein diets in overweight subjects. Int J Obes (Lond) 23, 1170-1177.
61. Curhan GC, Willett WC, Rimm EB et al. (1993) A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med 328, 833-838.
62. Breslau NA, Brinkley L, Hill KD et al. (1988) Relationship of animal protein rich diet to kidney stone formation and calcium metabolism. J Clin Endocrinol Metab 66, 140-146.
63. Hess B, Ackermann D, Essig M et al. (1995) Renal mass and serum calcitriol in male idiopathic calcium renal stone formers: role of protein intake. J Clin Endocrinol Metab 80, 1916-1921.
64. Hiatt RA, Ettinger B, Caan B et al. (1996) Randomized controlled trial of a low animal protein, high fiber diet in the prevention of recurrent calcium oxalate kidney stones. Am J Epidemiol 44, 25-33.
65. Brinkworth GD, Buckley JD, Noakes M et al. (2010) Renal function following long-term weight loss in individuals with abdominal obesity on a very-low-carbohydrate diet vs high-carbohydrate diet. J Am Diet Assoc 110, 633-638.
66. Li Z, Treyzon L, Chen S et al. (2010) Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial. Nutr J 31, 72.
67. Knight EL, Stampfer MJ, Hankinson SE et al. (2003) The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency. Ann Intern Med 138, 460-467.
68. Beasley JM, Aragaki AK, Lacroix AZ et al. (2011) Higher biomarker-calibrated protein intake is not associated with impaired renal function in postmenopausal women. J Nutr 141, 1502-1507.
69. Bowen J, Noakes M & Clifton PM (2005) Effect of calcium and dairy foods in high protein, energy-restricted diets on weight loss and metabolic parameters in overweight adults. Int J Obes (Lond) 29, 957-965.
70. Hu FB, Stampfer MJ, Manson JE et al. (1999) Dietary protein and risk of ischemic heart disease in women. Am J Clin Nutr 70, 221-227.
71. Iso H, Stampfer MJ, Manson JE et al. (2001) Prospective study of fat and protein intake and risk of intraparenchymal hemorrhage in women. Circulation 103, 856-863.
72. Obarzanek E, Velletri PA & Cutler JA (1996) Dietary protein and blood pressure. JAMA 275, 1598-1603.
73. Liu L, Ikeda K, SulliVan DH et al. (2002) Epidemiological evidence of the association between dietary protein intake and blood pressure: a meta-analysis of published data. Hypertens Res 25, 689-695.
74. Farnsworth E, Luscombe ND, Noakes M et al. (2003) Effect of a high protein, energy restricted diet on body composition, glycaemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women. Am J Clin Nutr 78, 31-94.
75. Parker B, Noakes M, Luscombe ND et al. (2002) Effect of a high protein, high monounsaturated fat weight loss diet on glycaemic control and lipid levels in type 2 diabetes. Diabetes Care 25, 425-430.
76. Wolfe BM & GioVannetti PM (1991) Short-term effects of substituting protein for carbohydrate in the diets of moderately hypercholesterolemic human subjects. Metabolism 40, 338-343.
77. Wolfe BM & PichéLA (1999) Replacement of carbohydrate by protein in a conventional-fat diet reduces cholesterol and triglyceride concentrations in healthy normolipidemic subjects. Clin Invest Med 22, 140-148.
78. Jenkins DJ, Kendall CW, Vidgen E et al. (2001) Highprotein diets in hyperlipidemia: effect of wheat gluten on serum lipids, uric acid, and renal function. Am J Clin Nutr 74, 57-63.
79. Alford BB, Blankenship AC & Hagen RD (1990) The effects of variations in carbohydrate, protein, and fat content of the diet upon weight loss, blood values, and nutrient intake of adult obese women. J Am Diet Assoc 90, 534-540.
80. Noakes M, Keogh JB, Foster PR et al. (2005) Effect of an energy restricted, high protein, low fat diet relative to a conventional high carbohydrate, low fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women. Am J Clin Nutr 81, 1298-1306.
81. Jenkins DJ, Wolever TM, Taylor RH et al. (1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34, 362-366.
82. Franzese TA (2000) Medical nutrition therapy for rheumatic disorders. In: Krause?s Food, Nutrition and Diet Therapy, 10th ed., pp. 970-986 [LK Mahan and S Escott-Stump, editors]. Philadelphia, PA: WB Saunders.
83. De Stefani E, Correa P, Boffetta P et al. (2004) Dietary patterns and risk of gastric cancer: a case-control study in Uruguay. Gastric Cancer 7, 211-220.
84. Rai A, Mohapatra SC & Shukla HS (2004) A review of association of dietary factors in gallbladder cancer. Indian J Cancer 41, 147-151.
85. Lagiou P, Olsen J & Trichopoulos D (2005) Consumption of vegetables and fruits and risk of breast cancer. JAMA 293, 2209.
86. Watzl B (2005) Consumption of vegetables and fruits and risk of breast cancer. JAMA 293, 2209-2210.
87. Vainio H & Miller AB (2003) Primary and secondary prevention in colorectal cancer. Acta Oncol 42, 809-815.
88. Chen MS, Chen D & Dou QP (2004) Inhibition of proteasome activity by various fruits and vegetables is associated with cancer cell death. In Vivo 18, 73-80.
89. Key TJ, Schatzkin A, Willett WC et al. (2004) Diet, nutrition and the prevention of cancer. Public Health Nutr 7, 187-200.
90. Adam-Perrot A, Clifton P & Brouns F (2006) Low-carbohydrate diets: nutritional and physiological aspects. Obes Rev 7, 49-58.
91. Chao A, Thun MJ, Connell CJ et al. (2005) Meat consumption and risk of colorectal cancer. JAMA 293, 172-182.
92. Norat T, Bingham S, Ferrari P et al. (2005) Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition. J Natl Cancer Inst 97, 906-916.
93. Campos FG, Logullo Waitzberg AG, Kiss DR et al. (2005) Diet and colorectal cancer: current evidence for etiology and prevention. Nutr Hosp 20, 18-25.
94. Balder HF, Goldbohm RA & Van den Brandt PA (2005) Dietary patterns associated with male lung cancer risk in the Netherlands Cohort Study. Cancer Epidemiol Biomarkers Prev 14, 483-490.
95. Sandhu MS, White IR & McPherson K (2001) Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach. Cancer Epidemiol Biomarkers Prev 10, 439-446.
96. Truswell AS (1999) Report of an expert workshop on meat intake and colorectal cancer risk convened in December 1998 in Adelaide, South Australia. Eur J Cancer Prev 8, 175-178.
97. National Academy of Sciences (1989) Diet and Health, p. 40. Washington, DC: National Academy Press.
98. Institute of Medicine (2002) Dietary Reference Intakes: Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academies Press.
99. US Department of Agriculture, US Department of Health and Human Services (2005) Dietary Guidelines for Americans, 6th ed. Washington, DC: US Government Printing Office.
100. Duncan SH, Lobley GE, Holtrop G et al. (2008) Human colonic microbiota associated with diet, obesity and weight loss. Int J Obes (Lond) 32, 1720-1724.
101. Brinkworth GD, Noakes M, Clifton PM et al. (2009) Comparative effects of very low-carbohydrate, high-fat and high-carbohydrate, low-fat weight-loss diets on bowel habit and faecal short-chain fatty acids and bacterial populations. Br J Nutr 101, 1493-1502.
102. Polivy J & Herman CP (1985) Dieting and bingeing: a casual analysis. Am Psychol 40, 193-201.
103. Stunkard AJ & Rush J (1974) Dieting and depression reexamined. Ann Intern Med 81, 526-533.
104. French SA & Jeffery RW (1994) Consequences of dieting to lose weight: effects on physical and mental health. Health Psychol 13, 195-212.
105. Lissner L, Odell PM, D?Agostino RB et al. (1991) Variability of body weight and health outcomes in the Framingham population. N Engl J Med 324, 1839-1844.
106. Wilson GT (1993) Relation of dieting and voluntary weight loss to psychological functioning and binge eating. Ann Intern Med 119(7 pt 2), 727-730.
107. Wooley SC & Wooley OW (1984) Should obesity be treated at all? In: Eating and Its Disorders, pp. 185-192 [AJ Stunkard & E Stellar, editors]. New York, USA: Raven Press.
108. Garner DM & Wooley SC (1991) Confronting the failure of behavioural and dietary treatments for obesity. Clin Psychol Rev 11, 729-780.
109. Lemmens SG, Born JM, Martens EA et al. (2011) Influence of consumption of a high-protein vs. highcarbohydrate meal on the physiological cortisol and psychological mood response in men and women. PLoS ONE 6, e16826.